BZ13-2 oil field is a deep submerged strongly volatile reservoir in Bohai Sea. This oil reservoir has the characteristics of high gas oil ratio and small difference in formation pressure and saturation point pressure....BZ13-2 oil field is a deep submerged strongly volatile reservoir in Bohai Sea. This oil reservoir has the characteristics of high gas oil ratio and small difference in formation pressure and saturation point pressure. It usually adopts gas injection development to avoid crude oil degassing and fast decreasing production capacity. However, the phase characteristics and miscibility mechanism of this high-temperature and high-pressure fluid after gas injection are not clear. Therefore, it is necessary to study the feasibility of CO<sub>2</sub> injection to improve oil recovery in near critical volatile oil reservoirs through CO<sub>2</sub> injection experiments. In the early stage of the depletion experiment, the content of heavy components in the remaining oil increased significantly, so the depletion method is not conducive to the development of such reservoirs. With the increase of CO<sub>2</sub> injection, the volumetric expansion coefficient of formation crude oil increases significantly, while the saturation pressure and formation crude oil viscosity remain basically unchanged. The minimum miscible pressure experiment shows that CO<sub>2</sub> injection under formation pressure conditions can achieve multiphase miscibility. Based on experimental research results, the BZ13-2 oilfield is suitable for early gas injection development and can significantly improve recovery.展开更多
In order to realize steady-state operation of the neutral beam injection（NBI） system with high beam energy,an accurate thermal analysis and a prediction about working conditions of heat-removal structures inside hig...In order to realize steady-state operation of the neutral beam injection（NBI） system with high beam energy,an accurate thermal analysis and a prediction about working conditions of heat-removal structures inside high-heat-flux（HHF） components in the system are key issues.In this paper,taking the HHF ion dump with swirl tubes in NBI system as an example,an accurate thermal dynamic simulation method based on computational fluid dynamics（CFD） and the finite volume method is presented to predict performance of the HHF component.In this simulation method,the Eulerian multiphase method together with some empirical corrections about the inter-phase transfer model and the wall heat flux partitioning model are considered to describe the subcooled boiling.The reliability of the proposed method is validated by an experimental example with subcooled boiling inside swirl tube.The proposed method provides an important tool for the refined thermal and flow dynamic analysis of HHF components,and can be extended to study the thermal design of other complex HHF engineering structures in a straightforward way.The simulation results also verify that the swirl tube is a promising heat removing structure for the HHF components of the NBI system.展开更多
Ultrasonic seismic model experiment plays an important role in engineering multi wave seismic prospecting(EMSP), which has been used to do the complex engineering seismic exploration. It is introduced that the applic...Ultrasonic seismic model experiment plays an important role in engineering multi wave seismic prospecting(EMSP), which has been used to do the complex engineering seismic exploration. It is introduced that the application of the technology in quality test of Yongjiang river submarine tunnel tube foundation in the paper. The material of the model was got from on the spot. The successful test has been made with results of the model experiment.展开更多
A polyethylene tube can be used as a heat exchanger for a low-running-cost?temperature control system. In this system, the flow of temperature-controlled?water in the tube is used as the heat source, and the tube is p...A polyethylene tube can be used as a heat exchanger for a low-running-cost?temperature control system. In this system, the flow of temperature-controlled?water in the tube is used as the heat source, and the tube is placed on the ceiling of a temperature-controlled space using a metal net. Owing to this structure, the tube is deformed by its weight. This deformation has a significant influence on heat transfer and flow characteristics. Therefore, an air injection method, in which air and water are injected simultaneously into the tube, is developed for preventing the deformation of the tube. In this study, bedding metal rods were used instead of a metal net. The influence of the pitch length of the metal rods (5 - 15 cm) and the width of the polyethylene tube 15, 20, 25, 30, and 35 cm was examined experimentally. The length of the polyethylene tube was 178 cm. The air flow rate was 9.5 × 10-5 m3/s. The water flow rates were 60, 80, 100, 120, and 140 mL/min. Results show that the thermal response improved because of air injection. In particular, the temperature at steady state increased, and steady state was attained approximately 1.2 - 3 times faster with air injection than without air injection. The optimum pitch length of the metal rods and the range of the optimum width of the polyethylene tube were 8 cm and 20 - 25 cm, respectively, with and without air injection.展开更多
AIM:To determine the effects of intravitreal resveratrol(RSV)on murine laser-induced choroidal neovascularization(CNV).METHODS:The toxicity of RSV to choroidal endothelial cell(CEC)was measured using thiazolyl blue te...AIM:To determine the effects of intravitreal resveratrol(RSV)on murine laser-induced choroidal neovascularization(CNV).METHODS:The toxicity of RSV to choroidal endothelial cell(CEC)was measured using thiazolyl blue tetrazolium bromide(M一)assay.Effects of RSV on choroidal endothelial cell(CEC)migration were evaluated with a modified Boyden chamber assay,while tube formation was evaluated in a 2-D gel assay.CNV was induced by laser photocoagulation in mice.The effects of intravitreal injection of RSV on CNV development were evaluated by fluorescein angiography(FA),confocal analysis of isolectin B4 labeled choroidal flat mounts,and histologic examination of CNV membranes.Immunostaining was used to analyze the expression and phosphorylation of vascular endothelial growth factor receptor 2(VEGFR2).RESULTS:No significant cell toxicity was observed in CEC if the concentration of RSV was less than 200 pmol/L(P>0.05).RSV inhibited vascular endothelial growth factor(VEGF)-induced CEC migration(P<0.05)and tube formation(P<0.05)invitro.Furthermore,intravitrealinjectionof RSV significantly inhibited laser induced CNV formation in mice.The FA leakage,CNV volume and CNV area analysis revealed that there were 41%,45%,and 58%reduction in RSV-treated eyes(1.691±0.1032,178163±78623μm^3 and 6508±619.0μm^2,respectively)compared with those in control(2.724±0.08447,379676±98382μm3and16576±2646μm^2,respectively;P<0.05).Phospho-VEGFR2expression was much weaker in the sections of CNV lesions in RSV injected mice compared with that in control(P<0.05).CONCLUSION:Intravitreal injection of RSV exerts an inhibitory effect on CNV,which may through suppressing endothelial cell migration,tube formation and VEGFR2 phosphorylation.展开更多
A new approach is demonstrated in which soft experimentation can be performed for MMP measurements, thus replacing the common practice of slim tube displacement laboratory experiments. Recovery potential from oil rese...A new approach is demonstrated in which soft experimentation can be performed for MMP measurements, thus replacing the common practice of slim tube displacement laboratory experiments. Recovery potential from oil reservoirs by miscible flue gas injection was studied by slim tube and field-scale numerical simulation using two flue gases and seven crude oils sampled at different depths in three candidate reservoirs. The soft experimentations were conducted using Eclipse300<sup>TM</sup>, a three-phase compositional simulator. This study investigates minimum miscibility pressure (MMP), a significant miscible gas injection project screening tool. Successful design of the project is contingent to the accurate determination of the MMP. This study evaluates effects of important factors such as injection pressure, oil component composition, and injection gas composition on the MMP and recovery efficiency for slim tube and field-scale displacements. Two applicable MMP correlations were used for comparison and validation purposes.展开更多
目的比较腹腔镜下T管缝合时预置缝线法与传统缝合方法的效果差异。方法回顾性分析2020年6月至2023年9月间空军特色医学中心行腹腔镜T管缝合的患者的临床资料,对照组采用传统的T管缝合方法,研究组采用预置缝线的T管缝合方法:间断缝合,进...目的比较腹腔镜下T管缝合时预置缝线法与传统缝合方法的效果差异。方法回顾性分析2020年6月至2023年9月间空军特色医学中心行腹腔镜T管缝合的患者的临床资料,对照组采用传统的T管缝合方法,研究组采用预置缝线的T管缝合方法:间断缝合,进针和出针时前一针的缝线不打紧,每组24例。比较两组患者T管缝合时间和注水试验阳性率。结果研究组术中T管缝合时间少于对照组[(12.61±0.88)min vs(17.62±0.58)min,t=-23.34,P<0.001],注水试验阳性率低于对照组[0 vs 25%(6/24),P=0.029],差异均有统计学意义。结论应用预置缝线的间断缝合法可提高腹腔镜下T管缝合速度,使缝合更确切,较传统方法有明显优势。展开更多
文摘BZ13-2 oil field is a deep submerged strongly volatile reservoir in Bohai Sea. This oil reservoir has the characteristics of high gas oil ratio and small difference in formation pressure and saturation point pressure. It usually adopts gas injection development to avoid crude oil degassing and fast decreasing production capacity. However, the phase characteristics and miscibility mechanism of this high-temperature and high-pressure fluid after gas injection are not clear. Therefore, it is necessary to study the feasibility of CO<sub>2</sub> injection to improve oil recovery in near critical volatile oil reservoirs through CO<sub>2</sub> injection experiments. In the early stage of the depletion experiment, the content of heavy components in the remaining oil increased significantly, so the depletion method is not conducive to the development of such reservoirs. With the increase of CO<sub>2</sub> injection, the volumetric expansion coefficient of formation crude oil increases significantly, while the saturation pressure and formation crude oil viscosity remain basically unchanged. The minimum miscible pressure experiment shows that CO<sub>2</sub> injection under formation pressure conditions can achieve multiphase miscibility. Based on experimental research results, the BZ13-2 oilfield is suitable for early gas injection development and can significantly improve recovery.
基金supported by the Special Program of ITER(International Thermonuclear Experimental Reactor)in China(No.2013GB101002)
文摘In order to realize steady-state operation of the neutral beam injection（NBI） system with high beam energy,an accurate thermal analysis and a prediction about working conditions of heat-removal structures inside high-heat-flux（HHF） components in the system are key issues.In this paper,taking the HHF ion dump with swirl tubes in NBI system as an example,an accurate thermal dynamic simulation method based on computational fluid dynamics（CFD） and the finite volume method is presented to predict performance of the HHF component.In this simulation method,the Eulerian multiphase method together with some empirical corrections about the inter-phase transfer model and the wall heat flux partitioning model are considered to describe the subcooled boiling.The reliability of the proposed method is validated by an experimental example with subcooled boiling inside swirl tube.The proposed method provides an important tool for the refined thermal and flow dynamic analysis of HHF components,and can be extended to study the thermal design of other complex HHF engineering structures in a straightforward way.The simulation results also verify that the swirl tube is a promising heat removing structure for the HHF components of the NBI system.
文摘Ultrasonic seismic model experiment plays an important role in engineering multi wave seismic prospecting(EMSP), which has been used to do the complex engineering seismic exploration. It is introduced that the application of the technology in quality test of Yongjiang river submarine tunnel tube foundation in the paper. The material of the model was got from on the spot. The successful test has been made with results of the model experiment.
文摘A polyethylene tube can be used as a heat exchanger for a low-running-cost?temperature control system. In this system, the flow of temperature-controlled?water in the tube is used as the heat source, and the tube is placed on the ceiling of a temperature-controlled space using a metal net. Owing to this structure, the tube is deformed by its weight. This deformation has a significant influence on heat transfer and flow characteristics. Therefore, an air injection method, in which air and water are injected simultaneously into the tube, is developed for preventing the deformation of the tube. In this study, bedding metal rods were used instead of a metal net. The influence of the pitch length of the metal rods (5 - 15 cm) and the width of the polyethylene tube 15, 20, 25, 30, and 35 cm was examined experimentally. The length of the polyethylene tube was 178 cm. The air flow rate was 9.5 × 10-5 m3/s. The water flow rates were 60, 80, 100, 120, and 140 mL/min. Results show that the thermal response improved because of air injection. In particular, the temperature at steady state increased, and steady state was attained approximately 1.2 - 3 times faster with air injection than without air injection. The optimum pitch length of the metal rods and the range of the optimum width of the polyethylene tube were 8 cm and 20 - 25 cm, respectively, with and without air injection.
基金Supported by the National Natural Science Foundation of China(No.81703134,No.81770952)Henan Province Nature Science Foundation of China(No.162300410296)Hunan Province Nature Science Foundation of China(No.2018JJ3772)。
文摘AIM:To determine the effects of intravitreal resveratrol(RSV)on murine laser-induced choroidal neovascularization(CNV).METHODS:The toxicity of RSV to choroidal endothelial cell(CEC)was measured using thiazolyl blue tetrazolium bromide(M一)assay.Effects of RSV on choroidal endothelial cell(CEC)migration were evaluated with a modified Boyden chamber assay,while tube formation was evaluated in a 2-D gel assay.CNV was induced by laser photocoagulation in mice.The effects of intravitreal injection of RSV on CNV development were evaluated by fluorescein angiography(FA),confocal analysis of isolectin B4 labeled choroidal flat mounts,and histologic examination of CNV membranes.Immunostaining was used to analyze the expression and phosphorylation of vascular endothelial growth factor receptor 2(VEGFR2).RESULTS:No significant cell toxicity was observed in CEC if the concentration of RSV was less than 200 pmol/L(P>0.05).RSV inhibited vascular endothelial growth factor(VEGF)-induced CEC migration(P<0.05)and tube formation(P<0.05)invitro.Furthermore,intravitrealinjectionof RSV significantly inhibited laser induced CNV formation in mice.The FA leakage,CNV volume and CNV area analysis revealed that there were 41%,45%,and 58%reduction in RSV-treated eyes(1.691±0.1032,178163±78623μm^3 and 6508±619.0μm^2,respectively)compared with those in control(2.724±0.08447,379676±98382μm3and16576±2646μm^2,respectively;P<0.05).Phospho-VEGFR2expression was much weaker in the sections of CNV lesions in RSV injected mice compared with that in control(P<0.05).CONCLUSION:Intravitreal injection of RSV exerts an inhibitory effect on CNV,which may through suppressing endothelial cell migration,tube formation and VEGFR2 phosphorylation.
文摘A new approach is demonstrated in which soft experimentation can be performed for MMP measurements, thus replacing the common practice of slim tube displacement laboratory experiments. Recovery potential from oil reservoirs by miscible flue gas injection was studied by slim tube and field-scale numerical simulation using two flue gases and seven crude oils sampled at different depths in three candidate reservoirs. The soft experimentations were conducted using Eclipse300<sup>TM</sup>, a three-phase compositional simulator. This study investigates minimum miscibility pressure (MMP), a significant miscible gas injection project screening tool. Successful design of the project is contingent to the accurate determination of the MMP. This study evaluates effects of important factors such as injection pressure, oil component composition, and injection gas composition on the MMP and recovery efficiency for slim tube and field-scale displacements. Two applicable MMP correlations were used for comparison and validation purposes.
文摘目的比较腹腔镜下T管缝合时预置缝线法与传统缝合方法的效果差异。方法回顾性分析2020年6月至2023年9月间空军特色医学中心行腹腔镜T管缝合的患者的临床资料,对照组采用传统的T管缝合方法,研究组采用预置缝线的T管缝合方法:间断缝合,进针和出针时前一针的缝线不打紧,每组24例。比较两组患者T管缝合时间和注水试验阳性率。结果研究组术中T管缝合时间少于对照组[(12.61±0.88)min vs(17.62±0.58)min,t=-23.34,P<0.001],注水试验阳性率低于对照组[0 vs 25%(6/24),P=0.029],差异均有统计学意义。结论应用预置缝线的间断缝合法可提高腹腔镜下T管缝合速度,使缝合更确切,较传统方法有明显优势。
