通过系统在不同运行模式下的实验研究,分析太阳辐照度、温度等参数对系统光伏光热性能的影响,结果表明光伏热泵组件发电效率比传统光伏组件提高16.4%;在获得同样热水情况下,混联运行比串联运行每天多输出1.7 k Wh的净发电量,热泵平均COP...通过系统在不同运行模式下的实验研究,分析太阳辐照度、温度等参数对系统光伏光热性能的影响,结果表明光伏热泵组件发电效率比传统光伏组件提高16.4%;在获得同样热水情况下,混联运行比串联运行每天多输出1.7 k Wh的净发电量,热泵平均COP从1.9升高到3.4。间接式光伏热泵系统将集热器的热量在蒸发器与冷凝器间进行合理分配后,比直膨式光伏热泵系统具有更好的综合性能。展开更多
Copolymer-1（Cop-1） is a peptide with immunomodulatory properties, approved by the Food and Drug Administration of United States in the treatment of multiple sclerosis. Cop-1 has been shown to exert neuroprotective e...Copolymer-1（Cop-1） is a peptide with immunomodulatory properties, approved by the Food and Drug Administration of United States in the treatment of multiple sclerosis. Cop-1 has been shown to exert neuroprotective effects and induce neurogenesis in cerebral ischemia models. Nevertheless, the mechanism involved in the neurogenic action of this compound remains unknown. The choroid plexus（CP） is a network of cells that constitute the interphase between the immune and central nervous systems, with the ability to mediate neurogenesis through the release of cytokines and growth factors. Therefore, the CP could play a role in Cop-1-induced neurogenesis. In order to determine the participation of the CP in the induction of neurogenesis after Cop-1 immunization, we evaluated the gene expression of various growth factors（brain-derived neurotrophic factor, insulin-like growth factor 1, neurotrophin-3） and cytokines（tumor necrosis factor alpha, interferon-gamma, interleukin-4（IL-4）, IL-10 and IL-17）, in the CP at 14 days after ischemia. Furthermore, we analyzed the correlation between the expression of these genes and neurogenesis. Our results showed that Cop-1 was capable of stimulating an upregulation in the expression of the genes encoding for brain-derived neurotrophic factor, insulin-like growth factor 1, neurotrophin-3 and IL-10 in the CP, which correlated with an increase in neurogenesis in the subventricular and subgranular zone. As well, we observed a downregulation of IL-17 gene expression. This study demonstrates the effect of Cop-1 on the expression of growth factors and IL-10 in the CP, in the same way, presents a possible mechanism involved in the neurogenic effect of Cop-1.展开更多
文摘通过系统在不同运行模式下的实验研究,分析太阳辐照度、温度等参数对系统光伏光热性能的影响,结果表明光伏热泵组件发电效率比传统光伏组件提高16.4%;在获得同样热水情况下,混联运行比串联运行每天多输出1.7 k Wh的净发电量,热泵平均COP从1.9升高到3.4。间接式光伏热泵系统将集热器的热量在蒸发器与冷凝器间进行合理分配后,比直膨式光伏热泵系统具有更好的综合性能。
基金supported by a grant from Universidad Anahuac México Norte(No.201425)
文摘Copolymer-1（Cop-1） is a peptide with immunomodulatory properties, approved by the Food and Drug Administration of United States in the treatment of multiple sclerosis. Cop-1 has been shown to exert neuroprotective effects and induce neurogenesis in cerebral ischemia models. Nevertheless, the mechanism involved in the neurogenic action of this compound remains unknown. The choroid plexus（CP） is a network of cells that constitute the interphase between the immune and central nervous systems, with the ability to mediate neurogenesis through the release of cytokines and growth factors. Therefore, the CP could play a role in Cop-1-induced neurogenesis. In order to determine the participation of the CP in the induction of neurogenesis after Cop-1 immunization, we evaluated the gene expression of various growth factors（brain-derived neurotrophic factor, insulin-like growth factor 1, neurotrophin-3） and cytokines（tumor necrosis factor alpha, interferon-gamma, interleukin-4（IL-4）, IL-10 and IL-17）, in the CP at 14 days after ischemia. Furthermore, we analyzed the correlation between the expression of these genes and neurogenesis. Our results showed that Cop-1 was capable of stimulating an upregulation in the expression of the genes encoding for brain-derived neurotrophic factor, insulin-like growth factor 1, neurotrophin-3 and IL-10 in the CP, which correlated with an increase in neurogenesis in the subventricular and subgranular zone. As well, we observed a downregulation of IL-17 gene expression. This study demonstrates the effect of Cop-1 on the expression of growth factors and IL-10 in the CP, in the same way, presents a possible mechanism involved in the neurogenic effect of Cop-1.
