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T2-weighted imaging-based radiomic-clinical machine learning model for predicting the differentiation of colorectal adenocarcinoma 被引量:1
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作者 Hui-Da Zheng Qiao-Yi Huang +4 位作者 Qi-Ming Huang Xiao-Ting Ke Kai Ye Shu Lin Jian-Hua Xu 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第3期819-832,共14页
BACKGROUND The study on predicting the differentiation grade of colorectal cancer(CRC)based on magnetic resonance imaging(MRI)has not been reported yet.Developing a non-invasive model to predict the differentiation gr... BACKGROUND The study on predicting the differentiation grade of colorectal cancer(CRC)based on magnetic resonance imaging(MRI)has not been reported yet.Developing a non-invasive model to predict the differentiation grade of CRC is of great value.AIM To develop and validate machine learning-based models for predicting the differ-entiation grade of CRC based on T2-weighted images(T2WI).METHODS We retrospectively collected the preoperative imaging and clinical data of 315 patients with CRC who underwent surgery from March 2018 to July 2023.Patients were randomly assigned to a training cohort(n=220)or a validation cohort(n=95)at a 7:3 ratio.Lesions were delineated layer by layer on high-resolution T2WI.Least absolute shrinkage and selection operator regression was applied to screen for radiomic features.Radiomics and clinical models were constructed using the multilayer perceptron(MLP)algorithm.These radiomic features and clinically relevant variables(selected based on a significance level of P<0.05 in the training set)were used to construct radiomics-clinical models.The performance of the three models(clinical,radiomic,and radiomic-clinical model)were evaluated using the area under the curve(AUC),calibration curve and decision curve analysis(DCA).RESULTS After feature selection,eight radiomic features were retained from the initial 1781 features to construct the radiomic model.Eight different classifiers,including logistic regression,support vector machine,k-nearest neighbours,random forest,extreme trees,extreme gradient boosting,light gradient boosting machine,and MLP,were used to construct the model,with MLP demonstrating the best diagnostic performance.The AUC of the radiomic-clinical model was 0.862(95%CI:0.796-0.927)in the training cohort and 0.761(95%CI:0.635-0.887)in the validation cohort.The AUC for the radiomic model was 0.796(95%CI:0.723-0.869)in the training cohort and 0.735(95%CI:0.604-0.866)in the validation cohort.The clinical model achieved an AUC of 0.751(95%CI:0.661-0.842)in the training cohort and 0.676(95%CI:0.525-0.827)in the validation cohort.All three models demonstrated good accuracy.In the training cohort,the AUC of the radiomic-clinical model was significantly greater than that of the clinical model(P=0.005)and the radiomic model(P=0.016).DCA confirmed the clinical practicality of incorporating radiomic features into the diagnostic process.CONCLUSION In this study,we successfully developed and validated a T2WI-based machine learning model as an auxiliary tool for the preoperative differentiation between well/moderately and poorly differentiated CRC.This novel approach may assist clinicians in personalizing treatment strategies for patients and improving treatment efficacy. 展开更多
关键词 Radiomics Colorectal cancer Differentiation grade Machine learning t2-weighted imaging
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退行性颈脊髓病MRI T2WI髓内高信号评价方法的研究进展
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作者 窦一博 魏磊鑫 +2 位作者 黄迟 王永立 曹鹏 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2024年第2期196-200,共5页
退行性颈脊髓病(degenerative cervical myelopathy,DCM)是全球范围内成人发生慢性脊髓神经功能障碍的最主要原因[1、2],包括脊髓型颈椎病(cervical spondylotic myelopathy,CSM)、颈椎后纵韧带骨化症(ossification of posterior longit... 退行性颈脊髓病(degenerative cervical myelopathy,DCM)是全球范围内成人发生慢性脊髓神经功能障碍的最主要原因[1、2],包括脊髓型颈椎病(cervical spondylotic myelopathy,CSM)、颈椎后纵韧带骨化症(ossification of posterior longitudinal ligament,OPLL)等。临床上,DCM患者常于磁共振(magnetic resonance imaging,MRI)T2加权像(T2-weighted image,T2WI)上出现髓内高信号(increased signal intensity,ISI)表现,其发生率可高达58%至85%[3]。ISI反映了脊髓组织的水肿、炎症、出血、缺血、坏死及胶质增生等一系列急慢性病理改变[4~7],具有重要的临床意义和科研价值。 展开更多
关键词 颈椎后纵韧带骨化症 脊髓型颈椎病 t2wi 颈脊髓病 髓内高信号 t2加权像 胶质增生 科研价值
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磁共振T2WI联合DWI对原发性直肠癌术前肿瘤分期及局部浸润程度的评估
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作者 孟葳 李丹丹 +1 位作者 陈静娴 单琴志 《影像技术》 CAS 2024年第6期60-64,共5页
目的:探讨磁共振T2WI联合DWI在原发性直肠癌术前肿瘤分期及局部浸润程度评估中的临床价值。方法:回顾性分析2022年1月至2024年5月期间,南方医科大学顺德医院收治的112例确诊为直肠癌患者的MRI资料,包括T2WI和DWI序列。以病理检查结果为... 目的:探讨磁共振T2WI联合DWI在原发性直肠癌术前肿瘤分期及局部浸润程度评估中的临床价值。方法:回顾性分析2022年1月至2024年5月期间,南方医科大学顺德医院收治的112例确诊为直肠癌患者的MRI资料,包括T2WI和DWI序列。以病理检查结果为金标准,评估MRI诊断的准确性。结果:MRI术前T、N分期诊断与术后病理诊断结果高度一致(P>0.05)。相较于单独的磁共振T2WI,磁共振T2WI联合DWI在评估肿瘤浸润和淋巴结转移方面表现出更高的准确性(P<0.05)。两者在检测直肠环周切缘(Circumferential Resection Margin,CRM)等异常病变方面无显著差异(P>0.05)。结论:磁共振T2WI联合DWI在直肠癌术前分期及局部浸润程度评估中具有较高的鉴别效能,为制定个性化治疗方案提供了有力支持。 展开更多
关键词 磁共振 t2wi DWI 原发性直肠癌 术前肿瘤分期 局部浸润程度
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基于宫颈癌术前T2WI影像组学特征预测近期预后的研究
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作者 陈薇 祝江红 +3 位作者 张新龙 邱玲琍 董婷 祝海峰 《宜春学院学报》 2024年第3期49-52,共4页
目的:探讨宫颈癌术前磁共振T2WI矢状位图的影像特征对近期预后的预测作用,构建并验证SVM预测模型。方法:回顾性选取2020年6月至2022年6月在我院接受宫颈癌手术治疗的患者80例,统计患者2年内预后情况,根据患者预后情况分为良好组(n=40)... 目的:探讨宫颈癌术前磁共振T2WI矢状位图的影像特征对近期预后的预测作用,构建并验证SVM预测模型。方法:回顾性选取2020年6月至2022年6月在我院接受宫颈癌手术治疗的患者80例,统计患者2年内预后情况,根据患者预后情况分为良好组(n=40)和不良组(n=40),再按7:3比例分为建模集(n=56)和验证集(n=24),收集患者术前MR-T2WI矢状位图的影像组学特征,使用单变量曲线下面积(Area under curve,AUC)分析及五折交叉验证的最低绝对收缩和选择算子LASSO回归算法进行特征筛选,以此构建SVM支持向量机预测模型。结果:SVM支持向量机结果显示,影响近期预后不良的前6位特征是灰度游程矩阵运行熵、灰度尺寸区域数量、灰度共生矩阵差异熵、一阶特征平均绝对偏差、运行长度不均匀度标准化、最大行2D直径,模型AUC为0.765,最佳截断值0.536对应的灵敏度、特异度分别为0.667、0.828。结论:基于宫颈癌术前T2WI影像组学特征构建的SVM支持向量机模型具有较好的预测效能,可为临床预防宫颈癌术后预后不良提供参考。 展开更多
关键词 宫颈癌 t2wi 影像组学 近期预后 预测模型
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磁共振DWI序列联合T2WI压脂序列对肛瘘的诊断价值
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作者 蔡邵媛 《现代医用影像学》 2024年第6期1090-1092,共3页
目的:研究肛瘘患者行磁共振DWI序列+T2WI压脂序列诊断的效果。方法:数据取自本院2021年1月1日至2022年12月31日收治122例肛瘘患者,均行磁共振检查的DWI序列、T2WI压脂序列扫描,以病理结果为“金标准”,分析诊断结果。结果:DWI序列的确... 目的:研究肛瘘患者行磁共振DWI序列+T2WI压脂序列诊断的效果。方法:数据取自本院2021年1月1日至2022年12月31日收治122例肛瘘患者,均行磁共振检查的DWI序列、T2WI压脂序列扫描,以病理结果为“金标准”,分析诊断结果。结果:DWI序列的确诊率为83.50%(86/103),T2WI压脂序列的确诊率为88.35%(91/103),联合扫描确诊率为97.09%(100/103),较单一扫描,联合扫描的诊断确诊率更高;P<0.05(具统计学意义)。结论:磁共振DWI序列+T2WI压脂序列诊断肛瘘可提高准确性、诊断效能,清晰显示内、外瘘口,为术前诊疗提供数据、值得推广。 展开更多
关键词 磁共振DWI序列 t2wi压脂序列 肛瘘 准确性 诊断效能
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联合应用MR动态增强及T2WI对Ⅰ、Ⅱ期子宫内膜癌的诊断价值
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作者 赵乃星 《现代医用影像学》 2024年第8期1489-1491,共3页
目的:分析联合应用磁共振成像(MRI)动态增强及T2WI对Ⅰ、Ⅱ期子宫内膜癌的诊断价值。方法:选取2018年1月至2023年11月35例子宫内膜癌患者,所有患者术前均行MR动态增强及T2WI检查,以手术病理组织学检查为金标准,评估MR动态增强及T2WI联... 目的:分析联合应用磁共振成像(MRI)动态增强及T2WI对Ⅰ、Ⅱ期子宫内膜癌的诊断价值。方法:选取2018年1月至2023年11月35例子宫内膜癌患者,所有患者术前均行MR动态增强及T2WI检查,以手术病理组织学检查为金标准,评估MR动态增强及T2WI联合应用的诊断价值。结果:手术病理组织学检查发现本组35例患者中按FIGO分期系统有Ⅰ、Ⅱ期25例,Ⅲ、Ⅳ期10例;MR动态增强检查结果为Ⅰ、Ⅱ期27例,Ⅲ、Ⅳ期8例;MR动态增强及T2WI联合应用检查结果为Ⅰ、Ⅱ期26例,Ⅲ、Ⅳ期9例,MR动态增强及T2WI联合应用对Ⅰ、Ⅱ期子宫内膜癌诊断的敏感度、特异度、准确度、阳性预测值、阴性预测值均高于单一MR动态增强检查,差异有统计学意义(P<0.05)。结论:MR动态增强及T2WI联合应用的诊断价值高,能够提高Ⅰ,Ⅱ期子宫内膜癌的诊断准确率,可推广使用。 展开更多
关键词 MR动态增强 t2wi 子宫内膜癌
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不同肠道准备剂在磁共振T2WI直肠高分辨成像中的应用效果比较
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作者 王丹 任静 +3 位作者 陈晓丽 郭玲 郭春玉 陆皓 《中国CT和MRI杂志》 2023年第1期145-147,共3页
目的 比较不同肠道准备剂对T2WI磁共振直肠高分辨成像图像质量的影响。方法 按入组条件筛选2020年6~12月在某三甲肿瘤专科医院行T2WI磁共振直肠高分辨成像的患者84例,按时间先后顺序前42例患者常规使用开塞露行肠道准备,为对照组;后42... 目的 比较不同肠道准备剂对T2WI磁共振直肠高分辨成像图像质量的影响。方法 按入组条件筛选2020年6~12月在某三甲肿瘤专科医院行T2WI磁共振直肠高分辨成像的患者84例,按时间先后顺序前42例患者常规使用开塞露行肠道准备,为对照组;后42例患者使用和爽行肠道准备,为观察组。由同一技师在同一设备使用相同序列行T2WI磁共振直肠高分辨成像,由中心两位具有10年临床诊断经验的正高医师行图像质量评价,得分3分及以上定义为图像满足诊断需要,得分5分为优秀。将优片率(得分5分患者所占比例)与欠佳率(得分1~2分患者所占比例)行统计学分析。结果 对照组5分图像质量4例、占9.52%,图像质量欠佳4例、占9.52%;观察组5分图像质量15例、占35.71%;图像质量欠佳1例、占2.38%。图像质量优片率观察组明显大于对照组,P<0.05;图像质量欠佳率观察组明显小于对照组,P<0.05。结论 使用和爽法行肠道准备较开塞露法能够提高T2WI磁共振直肠高分辨成像图像质量,具有临床可操作性及推广价值。 展开更多
关键词 开塞露 和爽 肠道准备 t2wi高分辨 磁共振直肠成像
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腰椎滑脱症棘间韧带磁共振T2WI、T1WI信号情况及临床意义
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作者 秦鑫 冯志慧 +2 位作者 许海娜 李江平 高波华 《颈腰痛杂志》 2023年第1期77-79,共3页
目的探讨腰椎滑脱症棘间韧带MRI的T2WI、T1WI信号情况及临床意义。方法纳入2018年1月~2021年1月本院收治的80例腰椎滑脱症患者,均采用3.0 T MR扫描,获取T2WI、T1WI影像资料。统计Ⅰ度滑脱、Ⅱ度滑脱、未滑脱节段的棘间韧带T2WI、T1WI信... 目的探讨腰椎滑脱症棘间韧带MRI的T2WI、T1WI信号情况及临床意义。方法纳入2018年1月~2021年1月本院收治的80例腰椎滑脱症患者,均采用3.0 T MR扫描,获取T2WI、T1WI影像资料。统计Ⅰ度滑脱、Ⅱ度滑脱、未滑脱节段的棘间韧带T2WI、T1WI信号情况,并统计各节段棘间韧带退变的MRI分型。结果80例患者中,Ⅰ度滑脱节段52个,Ⅱ度28个,未滑脱节段320个。Ⅱ度滑脱T2WI均为高信号,T1WI高信号6个;Ⅰ度滑脱T2WI高信号34个,T1WI高信号36个;未滑脱T2WI高信号44个,T1WI高信号38个;Ⅱ度滑脱棘间韧带MRI分型以C型为主,Ⅰ度滑脱B型为主,未滑脱A型为主。结论腰椎滑脱症的滑脱节段棘间韧带MRI常见T2WI高信号,滑脱越严重,则棘间韧带退变情况也更加严重,在MRI诊断中应给予重视。 展开更多
关键词 腰椎退变 腰椎滑脱症 棘间韧带 磁共振 t2wi信号 T1WI信号
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联合应用MR动态增强及T2WI对Ⅰ、Ⅱ期子宫内膜癌的诊断价值
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作者 赵乃星 《现代医用影像学》 2024年第8期1489-1491,共3页
目的:分析联合应用磁共振成像(MR)动态增强及T2WI对Ⅰ,Ⅱ期子宫内膜癌的诊断价值。方法:选取2018年1月-2023年11月35例子宫内膜癌患者,所有javascript;患者术前均行MR动态增强及T2WI检查,以手术病理组织学检查为金标准,评估MR动态增强及... 目的:分析联合应用磁共振成像(MR)动态增强及T2WI对Ⅰ,Ⅱ期子宫内膜癌的诊断价值。方法:选取2018年1月-2023年11月35例子宫内膜癌患者,所有javascript;患者术前均行MR动态增强及T2WI检查,以手术病理组织学检查为金标准,评估MR动态增强及T2WI联合应用的诊断价值。结果:手术病理组织学检查发现本组35例患者中按FIGO分期系统分期Ⅰ、Ⅱ期25例,Ⅲ、Ⅳ期10例;MR动态增强检查结果为Ⅰ、Ⅱ期27例,Ⅲ、Ⅳ期8例;MR动态增强及T2WI联合应用检查结果为Ⅰ、Ⅱ期26例,Ⅲ、Ⅳ期9例,MR动态增强及T2WI联合应用对Ⅰ,Ⅱ期子宫内膜癌诊断的敏感度、特异度、准确度、阳性预测值、阴性预测值高于单一MR动态增强检查,差异有统计学意义(P<0.05)。结论:MR动态增强及T2WI联合应用的诊断价值高,能够提高Ⅰ,Ⅱ期子宫内膜癌的诊断准确率,可推广使用。 展开更多
关键词 MR动态增强 t2wi 子宫内膜癌
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Differential Diagnostic Value of Texture Feature Analysis of Magnetic Resonance T2 Weighted Imaging between Glioblastoma and Primary Central Neural System Lymphoma 被引量:5
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作者 王波涛 刘明霞 陈志晔 《Chinese Medical Sciences Journal》 CAS CSCD 2019年第1期10-17,共8页
Objective To investigate the difference in tumor conventional imaging findings and texture features on T2 weighted images between glioblastoma and primary central neural system(CNS) lymphoma. Methods The pre-operative... Objective To investigate the difference in tumor conventional imaging findings and texture features on T2 weighted images between glioblastoma and primary central neural system(CNS) lymphoma. Methods The pre-operative MRI data of 81 patients with glioblastoma and 28 patients with primary CNS lymphoma admitted to the Chinese PLA General Hospital and Hainan Hospital of Chinese PLA General Hospital were retrospectively collected. All patients underwent plain MR imaging and enhanced T1 weighted imaging to visualize imaging features of lesions. Texture analysis of T2 weighted imaging(T2 WI) was performed by use of GLCM texture plugin of ImageJ software, and the texture parameters including Angular Second Moment(ASM), Contrast, Correlation, Inverse Difference Moment(IDM), and Entropy were measured. Independent sample t-test and Mann-Whitney U test were performed for the between-group comparisons, regression model was established by Binary Logistic regression analysis, and receiver operating characteristic(ROC) curve was plotted to compare the diagnostic efficacy. Results The conventional imaging features including cystic and necrosis changes(P = 0.000), ‘Rosette' changes(P = 0.000) and ‘incision sign'(P = 0.000), except ‘flame-like edema'(P = 0.635), presented significantly statistical difference between glioblastoma and primary CNS lymphoma. The texture features, ASM, Contrast, Correlation, IDM and Entropy, showed significant differences between glioblastoma and primary CNS lympoma(P = 0.006,0.000, 0.002, 0.000, and 0.015 respectively). The area under the ROC curve was 0.671, 0.752, 0.695, 0.720 and 0.646 respectively, and the area under the ROC curve was 0.917 for the combined texture variables(Contrast, cystic and necrosis, ‘Rosette' changes, and ‘incision sign') in the model of Logistic regression. Binary Logistic regression analysis demonstrated that cystic and necrosis changes, ‘Rosette' changes and ‘incision sign' and texture Contrast could be considered as the specific texture variables for the differential diagnosis of glioblastoma and primary CNS lymphoma. Conclusion The texture features of T2 WI and conventional imaging findings may be used to distinguish glioblastoma from primary CNS lymphoma. 展开更多
关键词 GLIOBLASTOMA primary CENTRAL NEURAL system LYMPHOMA texture analysis t2 weighted imaging differential diagnosis
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Asymmetrically hypointense veins on T2~*w imaging and susceptibility-weighted imaging in ischemic stroke 被引量:14
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作者 Ulf Jensen-Kondering Ruwen Bhm 《World Journal of Radiology》 CAS 2013年第4期156-165,共10页
AIM:To review the literature on the assessment of venous vessels to estimate the penumbra on T2*w imaging and susceptibility-weighted imaging (SWI). METHODS:Literature that reported on the assessment of penumbra by T2... AIM:To review the literature on the assessment of venous vessels to estimate the penumbra on T2*w imaging and susceptibility-weighted imaging (SWI). METHODS:Literature that reported on the assessment of penumbra by T2*w imaging or SWI and used a validation method was included. PubMed and relevant stroke and magnetic resonance imaging (MRI) related conference abstracts were searched. Abstracts that had overlapping content with full text articles were excluded. The retrieved literature was scanned for further relevant references. Only clinical literature published in English was considered, patients with Moya-Moya syndrome were disregarded. Data is given as cumulative absolute and relative values, ranges are given where appropriate. RESULTS:Forty-three publications including 1145 patients could be identified. T2*w imaging was used in 16 publications (627 patients), SWI in 26 publications (453 patients). Only one publication used both (65 patients). The cumulative presence of hypointense vessel sign was 54% (range 32%-100%) for T2* (668 patients) and 81% (range 34%-100%) for SWI (334 patients). There was rare mentioning of interrater agreement (6 publications, 210 patients) and reliability (1 publication, 20 patients) but the numbers reported ranged from good to excellent. In most publications (n = 22) perfusion MRI was used as a validation method (617 patients). More patients were scanned in the subacute than in the acute phase (596 patients vs 320 patients). Clinical outcome was reported in 13 publications (521 patients) but was not consistent. CONCLUSION:The low presence of vessels signs on T2*w imaging makes SWI much more promising. More research is needed to obtain formal validation and quantification. 展开更多
关键词 Acute ISCHEMIC stroke Oxygen extraction fraction Susceptibility-weighted imaging t2* PENUMBRA
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3.0T磁共振T2WI联合DCE与DWI对前列腺癌的诊断价值分析 被引量:1
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作者 陈锡军 史学权 《生命科学仪器》 2023年第S01期20-20,共1页
目的:分析前列腺癌诊断过程中,应用3.0T磁共振(MRI)T2WI联合DCE(动态对比增强)与DWI(弥散加权成像)诊断方法的实际诊断价值。方法:在我院2021年12月份至2022年12月份经病理诊断确诊为前列腺癌的患者中选出32例,采用随机抽签法以不同诊... 目的:分析前列腺癌诊断过程中,应用3.0T磁共振(MRI)T2WI联合DCE(动态对比增强)与DWI(弥散加权成像)诊断方法的实际诊断价值。方法:在我院2021年12月份至2022年12月份经病理诊断确诊为前列腺癌的患者中选出32例,采用随机抽签法以不同诊断方式统计诊断结果。T2WI组应用3.0T磁共振T2WI序列诊断方式,DWI+T2WI组应用T2WI序列联合DWI,DCE+DWI+T2WI组应用MRIT2WI序列、DCE联合DWI诊断方式,比较前列腺癌疾病检出率。结果:T2WI组前列腺癌检出率43.75%,DWI+T2WI组检出率59.38%,DCE+DWI+T2WI组中检出率90.63%,数据较高,组间数据比对存在统计学差异(P=0.001)。结论:前列腺癌诊断中3.0TMRIT2WI联合DCE与DWI能获得高精度诊断结果,故此可推广综合诊断方法。 展开更多
关键词 前列腺癌 3.0T磁共振 t2wi序列 DWI DCE
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Three-dimensional time-of-flight magnetic resonance angiography combined with high resolution T2-weighted imaging in preoperative evaluation of microvascular decompression 被引量:2
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作者 Chen Liang Ling Yang +2 位作者 Bin-Bin Zhang Shi-Wen Guo Rui-Chun Li 《World Journal of Clinical Cases》 SCIE 2022年第34期12594-12604,共11页
BACKGROUND Neurovascular compression(NVC) is the main cause of primary trigeminal neuralgia(TN) and hemifacial spasm(HFS). Microvascular decompression(MVD) is an effective surgical method for the treatment of TN and H... BACKGROUND Neurovascular compression(NVC) is the main cause of primary trigeminal neuralgia(TN) and hemifacial spasm(HFS). Microvascular decompression(MVD) is an effective surgical method for the treatment of TN and HFS caused by NVC. The judgement of NVC is a critical step in the preoperative evaluation of MVD, which is related to the effect of MVD treatment. Magnetic resonance imaging(MRI) technology has been used to detect NVC prior to MVD for several years. Among many MRI sequences, three-dimensional time-of-flight magnetic resonance angiography(3D TOF MRA) is the most widely used. However, 3D TOF MRA has some shortcomings in detecting NVC. Therefore, 3D TOF MRA combined with high resolution T2-weighted imaging(HR T2WI) is considered to be a more effective method to detect NVC.AIM To determine the value of 3D TOF MRA combined with HR T2WI in the judgment of NVC, and thus to assess its value in the preoperative evaluation of MVD.METHODS Related studies published from inception to September 2022 based on PubMed, Embase, Web of Science, and the Cochrane Library were retrieved. Studies that investigated 3D TOF MRA combined with HR T2WI to judge NVC in patients with TN or HFS were included according to the inclusion criteria. Studies without complete data or not relevant to the research topics were excluded. The Quality Assessment of Diagnostic Accuracy Studies checklist was used to assess the quality of included studies. The publication bias of the included literature was examined by Deeks’ test. An exact binomial rendition of the bivariate mixed-effects regression model was used to synthesize data. Data analysis was performed using the MIDAS module of statistical software Stata 16.0. Two independent investigators extracted patient and study characteristics, and discrepancies were resolved by consensus. Individual and pooled sensitivities and specificities were calculated. The I_(2) statistic and Q test were used to test heterogeneity. The study was registered on the website of PROSERO(registration No. CRD42022357158).RESULTS Our search identified 595 articles, of which 12(including 855 patients) fulfilled the inclusion criteria. Bivariate analysis showed that the pooled sensitivity and specificity of 3D TOF MRA combined with HR T2WI for detecting NVC were 0.96 [95% confidence interval(CI): 0.92-0.98] and 0.92(95%CI: 0.74-0.98), respectively. The pooled positive likelihood ratio was 12.4(95%CI: 3.2-47.8), pooled negative likelihood ratio was 0.04(95%CI: 0.02-0.09), and pooled diagnostic odds ratio was 283(95%CI: 50-1620). The area under the receiver operating characteristic curve was 0.98(95%CI: 0.97-0.99). The studies showed no substantial heterogeneity(I2 = 0, Q = 0.001 P = 0.50).CONCLUSION Our results suggest that 3D TOF MRA combined with HR T2WI has excellent sensitivity and specificity for judging NVC in patients with TN or HFS. This method can be used as an effective tool for preoperative evaluation of MVD. 展开更多
关键词 Three-dimensional time-of-flight magnetic resonance angiography High resolution t2 weighted imaging Neurovascular compression Microvascular decompression META-ANALYSIS
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高分辨T2WI形态学参数预测直肠癌临床分期的价值
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作者 朱先锋 黄国权 +4 位作者 张虎 汤凯 张晓金 张林杰 杨澜 《沈阳医学院学报》 2023年第5期470-474,共5页
目的:探讨高分辨T2WI(HR-T2WI)形态学参数预测直肠癌临床分期的价值。方法:回顾性分析2019年3月至2022年10月于我院行直肠MRI检查并行手术治疗,经组织病理学证实的78例直肠癌患者的临床资料,根据术后病理分为Ⅰ期(T_(1-2)N_(0)M_(0))、... 目的:探讨高分辨T2WI(HR-T2WI)形态学参数预测直肠癌临床分期的价值。方法:回顾性分析2019年3月至2022年10月于我院行直肠MRI检查并行手术治疗,经组织病理学证实的78例直肠癌患者的临床资料,根据术后病理分为Ⅰ期(T_(1-2)N_(0)M_(0))、Ⅱ期(T3-4N_(0)M_(0))+Ⅲ期(任何T、N1-2M_(0))2组。运用HR-T2WI测量肿瘤最大厚度(MTT)、肿瘤长径(MTL)、肿瘤下缘距肛门距离(DTA)、肿瘤最大截面积(MTA)、肿瘤体积(GTV),并评判肿瘤是否累及肠管全周。采用Spearman检验分析各指标间的相关性;采用受试者工作特征(ROC)曲线分析各参数预测直肠癌临床分期的价值。结果:Ⅰ期、Ⅱ+Ⅲ期患者MTL、GTV、环周受累情况比较差异均有统计学意义(P<0.05);AUC值分别为0.732、0.716、0.791(P<0.05)。MTL和GTV呈正相关(r=0.779,P<0.01)。以MTL>3.65 cm联合环周受累诊断直肠癌临床分期的AUC值为0.842;以GTV>17.96 cm3联合环周受累诊断直肠癌临床分期的AUC值为0.838。结论:HR-T2WI参数MTL、GTV、环周受累在鉴别Ⅰ期、Ⅱ+Ⅲ期直肠癌中价值较高,MTL联合环周受累收益最高,可有效筛选出新辅助放化疗(nCRT)获益者。 展开更多
关键词 磁共振成像 直肠癌 高分辨t2wi 临床分期
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Comparison of Diagnostic Effects of T2-Weighted Imaging,DWI,SWI,and DTI in Acute Cerebral Infarction
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作者 Yu-quan Zheng Xiao-mei Li 《Cardiovascular Innovations and Applications》 2021年第2期283-287,共5页
Objective:To achieve precision medicine,the use of imaging methods to help the clinical detection of cerebral infarction is conducive to the clinical development of a treatment plan and increase of the cure rate and i... Objective:To achieve precision medicine,the use of imaging methods to help the clinical detection of cerebral infarction is conducive to the clinical development of a treatment plan and increase of the cure rate and improvement of the prognosis of patients.Methods:In this work,T2-weighted imaging(T2WI),diffusion-weighted imaging(DWI),susceptibility-weighted imaging(SWI),and diffusion tensor imaging(DTI)examinations were performed on 34 patients with clinically diagnosed cerebral infarction to measure the difference in signal intensity between the lesion and its mirror area and make a comparative analysis by means of the Student-Newman-Keuls method.Results:The detection rate of T2WI was 79%(27/34),the detection rate of DWI was 97%(33/34),the detection rate of SWI was 88%(30/34),and the detection rate of DTI was 94%(32/34).Conclusion:The imaging performance was in the order DWI>DTI>SWI>T2WI for the diagnosis of cerebral infarction,and combined imaging is better than single imaging. 展开更多
关键词 t2-weighted imaging susceptibility-weighted imaging diffusion tensor imaging diffusion-weighted imaging cerebral infarction
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脊髓型颈椎病MRI T2WI高信号与患者手术预后关系的Meta分析 被引量:9
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作者 李凤宁 陈智 +3 位作者 张帆 李全 沈洪兴 侯铁胜 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2011年第1期83-84,共2页
脊髓型颈椎病(cervical spondylotic myelopathy,CSM)是一种退行性疾病,常伴有脊髓损害。Takahashi等首先描述了CSM患者MRI上T2加权像(T2-weighted images,T2WI)可出现脊髓高信号的现象,
关键词 脊髓型颈椎病 META分析 MRI 高信号 手术预后 t2wi 患者 退行性疾病
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磁共振T2WI压脂序列在Modic改变分型中应用价值研究 被引量:5
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作者 许凤 邹月芬 +1 位作者 徐磊 冯阳 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2014年第11期1609-1613,共5页
目的 :评价在1.5T的MR系统成像仪中T2WI压脂序列在Modic改变分型中的应用价值。方法 :回顾性分析2013年11月~2014年3月间因腰腿痛行腰椎MRI检查的276例患者的MRI资料,进行Modic分型的对比研究。通过双盲法采用两种方法进行分型。分... 目的 :评价在1.5T的MR系统成像仪中T2WI压脂序列在Modic改变分型中的应用价值。方法 :回顾性分析2013年11月~2014年3月间因腰腿痛行腰椎MRI检查的276例患者的MRI资料,进行Modic分型的对比研究。通过双盲法采用两种方法进行分型。分别是方法 1:T1WI、T2WI序列;方法 2:T1WI、T2WI、T2WI-FS序列。2位医师分别采用方法 1、2将Modic改变分型。结果:两位医师分型结果一致率分别为方法 1:98.66%,Kappa=0.925(P〈0.001);方法 2:99.49%,Kappa=0.975(P〈0.001)。采用方法 1、2将终板退变分为ModicⅠ型、Ⅱ型、Ⅲ型、混合型,且两种方法检出个数差异有统计学意义(P〈0.001)。同时对混合型进一步分析亚型,分7个亚型,分别为Ⅰ/Ⅱ、Ⅱ/Ⅰ、Ⅲ/Ⅱ、Ⅱ/Ⅲ、Ⅰ/Ⅲ、Ⅲ/Ⅰ、Ⅰ/Ⅱ/Ⅲ型,其中Ⅰ/Ⅱ型和Ⅱ/Ⅰ型最多。结论:磁共振T2WI压脂序列联合T1WI、T2WI序列能在影像学上提高对ModicⅠ型、混合型的检出率,对Modic改变分型优于传统的T1WI和T2WI序列,还可依改变区域MR信号对混合型进一步分类。 展开更多
关键词 MRI MODIC改变 分型 t2wi压脂序列
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MR高分辨T2WI联合IVIM对直肠癌壁外血管侵犯的预测价值 被引量:7
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作者 傅爱燕 段书峰 +1 位作者 冯峰 尹海兵 《山东医药》 CAS 2020年第10期52-54,共3页
目的探讨MR高分辨T2WI(HR-T2WI)联合基于体素内不相干运动(IVIM)对直肠癌壁外血管侵犯(EMVI)的预测价值。方法选择73例直肠癌患者,患者术前均行HR-T2WI、IVIM检查。两位阅片者分别对有、无IVIM图像进行独立分析。采用Kappa分析比较两位... 目的探讨MR高分辨T2WI(HR-T2WI)联合基于体素内不相干运动(IVIM)对直肠癌壁外血管侵犯(EMVI)的预测价值。方法选择73例直肠癌患者,患者术前均行HR-T2WI、IVIM检查。两位阅片者分别对有、无IVIM图像进行独立分析。采用Kappa分析比较两位阅片者采用两种成像方法诊断直肠癌EMVI的一致性,并分别绘制对应的受试者工作特征(ROC)曲线,采用DeLong检验进行比较。采用χ^2检验对两位阅片者增加IVIM前后诊断直肠癌EMVI的敏感性、阳性预测值进行比较。结果两位阅片者采用MRI HR-T2WI联合IVIM检查较单独HR-T2WI,诊断EMVI一致性提高,诊断EMVI的ROC曲线下面积均增加(P均<0.05),诊断EMVI的敏感性及阳性预测值均提高,但差异无统计学意义。结论HR-T2WI联合IVIM可增强阅片者对直肠癌EMVI的诊断信心,提高阅片者的一致性,同时提升诊断效能。 展开更多
关键词 直肠癌 磁共振成像 高分辨t2wi 体素内不相干运动 壁外血管侵犯
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基于T2WI灰度共生矩阵在鉴别高低级别胶质瘤中的应用 被引量:6
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作者 李烨 盛伟华 +3 位作者 阮娇妮 蔡华亮 黄松 宋黎涛 《中国医学计算机成像杂志》 CSCD 北大核心 2018年第5期430-433,共4页
目的:探讨T2WI灰度共生矩阵参数在鉴别高低级别胶质瘤中的价值。方法:收集54例病理证实为胶质瘤患者,其中高级别胶质瘤31例,低级别胶质瘤27例。在T2WI图像上使用ImageJ软件手动勾画出肿瘤最大层面的ROI,采用基于Matlab编写的软件提出灰... 目的:探讨T2WI灰度共生矩阵参数在鉴别高低级别胶质瘤中的价值。方法:收集54例病理证实为胶质瘤患者,其中高级别胶质瘤31例,低级别胶质瘤27例。在T2WI图像上使用ImageJ软件手动勾画出肿瘤最大层面的ROI,采用基于Matlab编写的软件提出灰度共生矩阵相关纹理特征,包括相关、能量,逆差距和熵,并采用独立样本t检验比较高低级别胶质瘤各特征间的差异,对于有统计学意义的特征绘制受试者工作特征曲线(ROC),并计算界值相应的敏感性和特异性。结果:高级别胶质瘤的纹理特征逆差距有意义较低级别低(P<0.001),高低级别胶质瘤的纹理特征相关性,能量和熵无统计学差异(P=0.261-0.849)。逆差距的ROC曲线下面积为0.895,以0.972为界值鉴别高低级别胶质瘤的敏感性和特异性分别为93.8%和75.0%。结论:基于T2WI灰度共生矩阵可用于鉴别高低级别胶质瘤,逆差距是鉴别二者的重要指标。 展开更多
关键词 胶质瘤 灰度共生矩阵 t2wi
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评估T2WI和超高b值扩散加权成像联合使用对移行区前列腺癌的诊断价值 被引量:6
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作者 郭静 高强 +2 位作者 李军东 马翠萍 徐成 《中国药物与临床》 CAS 2018年第11期1926-1927,共2页
目前认为,第2版前列腺影像报告与数据系统(PI-RADSv2)可为诊断移行区PCa提供半定量标准[1]。PI-RADSv2以T2WI作为诊断移行区PCa的主要序列,DWI为补充序列[2]。本研究通过联合T2WI、常规b值DWI(b值=1000s/mm2)和超高b值DWI(b值=2000s/mm2... 目前认为,第2版前列腺影像报告与数据系统(PI-RADSv2)可为诊断移行区PCa提供半定量标准[1]。PI-RADSv2以T2WI作为诊断移行区PCa的主要序列,DWI为补充序列[2]。本研究通过联合T2WI、常规b值DWI(b值=1000s/mm2)和超高b值DWI(b值=2000s/mm2)对移行区PCa癌进行分析,评价其对移行区PCa的诊断价值。 展开更多
关键词 诊断价值 前列腺癌 移行区 扩散加权成像 联合使用 t2wi B值 t2wi
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