Background: Diabetes means the blood glucose, which is too high or too low. With Type 2 DM, the more common type, the body does not make or use insulin well. In patients with DM, Helicobacter pylori is one of the most...Background: Diabetes means the blood glucose, which is too high or too low. With Type 2 DM, the more common type, the body does not make or use insulin well. In patients with DM, Helicobacter pylori is one of the most common infections worldwide. Available data on the possible association between H. pylori infection and DM are contradictory. There are a few studies in the Middle East, and this study is the pioneer study, in the Medical Services Clinics in Gaza strip. Aims: This study was conducted to reveal the prevalence of H. pylori infection, malnutrition, insulin resistance among T2DM patients, to describe the dietary requirements of T2DM patients, finally to evaluate the current information about diet, and lifestyle in the prevention of H. pylori, and malnutrition. Methodology: A cross-sectional study was conducted in the Medical Services Clinics in Gaza Strip, and there were 129 patients included in this study. Data were collected through hematological information and structured interview questionnaire. Results: Highly significant percentage of H. pylori (70%) among the DM patients includes in the study, but not indicates any significant association between gender and H. pylori status. Conclusion: H. pylori patients should update their sugar level values in the record, and should get exercise and diet plan for every meal.展开更多
Polycystic ovarian syndrome (PCOS) is an endocrine disorder that affects women of reproductive age and is characterized by hyperandrogenism, unpredictable ovulation, and a polycystic ovary shape. It is accompanied by ...Polycystic ovarian syndrome (PCOS) is an endocrine disorder that affects women of reproductive age and is characterized by hyperandrogenism, unpredictable ovulation, and a polycystic ovary shape. It is accompanied by metabolic problems, such as obesity and insulin resistance (IR). Factors contributing to PCOS include genetics, epigenetic changes, environmental factors, oxidative stress, chronic inflammation, mitochondrial dysfunction, and metabolic abnormalities. Insulin resistance is the most prevalent classical phenotype, and metformin was the first insulin-sensitizing drug to be used to study its role. Metformin, derived from galegine, inhibits mitochondrial function, activates AMPK, enhances hepatic insulin sensitivity, and lowers the risk of type 2 diabetes in PCOS patients. It also affects tumor growth, with a 30% reduction in the overall tumor onsets in T2DM patients. Metformin treatment has been linked to low rates of multiple pregnancies, increased fetal concentrations of sex hormone-binding globulin, and decreased levels of inflammatory cytokines. It can reduce the risk of endometrial cancer, type 2 diabetes mellitus, cardiovascular disease, dyslipidemia, and hypertension in women with PCOS.展开更多
文摘Background: Diabetes means the blood glucose, which is too high or too low. With Type 2 DM, the more common type, the body does not make or use insulin well. In patients with DM, Helicobacter pylori is one of the most common infections worldwide. Available data on the possible association between H. pylori infection and DM are contradictory. There are a few studies in the Middle East, and this study is the pioneer study, in the Medical Services Clinics in Gaza strip. Aims: This study was conducted to reveal the prevalence of H. pylori infection, malnutrition, insulin resistance among T2DM patients, to describe the dietary requirements of T2DM patients, finally to evaluate the current information about diet, and lifestyle in the prevention of H. pylori, and malnutrition. Methodology: A cross-sectional study was conducted in the Medical Services Clinics in Gaza Strip, and there were 129 patients included in this study. Data were collected through hematological information and structured interview questionnaire. Results: Highly significant percentage of H. pylori (70%) among the DM patients includes in the study, but not indicates any significant association between gender and H. pylori status. Conclusion: H. pylori patients should update their sugar level values in the record, and should get exercise and diet plan for every meal.
文摘Polycystic ovarian syndrome (PCOS) is an endocrine disorder that affects women of reproductive age and is characterized by hyperandrogenism, unpredictable ovulation, and a polycystic ovary shape. It is accompanied by metabolic problems, such as obesity and insulin resistance (IR). Factors contributing to PCOS include genetics, epigenetic changes, environmental factors, oxidative stress, chronic inflammation, mitochondrial dysfunction, and metabolic abnormalities. Insulin resistance is the most prevalent classical phenotype, and metformin was the first insulin-sensitizing drug to be used to study its role. Metformin, derived from galegine, inhibits mitochondrial function, activates AMPK, enhances hepatic insulin sensitivity, and lowers the risk of type 2 diabetes in PCOS patients. It also affects tumor growth, with a 30% reduction in the overall tumor onsets in T2DM patients. Metformin treatment has been linked to low rates of multiple pregnancies, increased fetal concentrations of sex hormone-binding globulin, and decreased levels of inflammatory cytokines. It can reduce the risk of endometrial cancer, type 2 diabetes mellitus, cardiovascular disease, dyslipidemia, and hypertension in women with PCOS.
