Objective:To investigate the effect of high-intensity interval training on blood glucose control, adipocytokine secretion and oxidative stress response in patients with T2DM.Methods: A total of 92 patients with newly ...Objective:To investigate the effect of high-intensity interval training on blood glucose control, adipocytokine secretion and oxidative stress response in patients with T2DM.Methods: A total of 92 patients with newly diagnosed T2DM who were treated in this hospital between July 2016 and July 2017 were divided into the control group (n=46) and HIIT group (n=46) by random number table method. Control group received conventional hypoglycemic therapy, HIIT group received hypoglycemic combined with high-intensity interval training therapy, and the intervention lasted for 3 months. The differences in blood glucose control, adipocytokine secretion and oxidative stress response were compared between the two groups before and after intervention.Results: Before intervention, the differences in blood glucose index levels in peripheral blood as well as the contents of adipocytokines and oxidative stress indexes in serum were not statistically significant between the two groups of patients. After 3 months of intervention, blood glucose indexes FPG, FINS and 2hPBG levels in peripheral blood of HIIT group were lower than those of control group;adipocytokine APN content in serum was higher than that of control group whereas LEP, Resistin and CHEM contents were lower than those of control group;oxidative stress indexes MDA and ROS contents in serum were lower than those of control group whereas T-AOC content was higher than that of control group. Conclusion: Routine hypoglycemic therapy combined with high-intensity interval training can further control the blood glucose levels, regulate the secretion of adipocytokines and reduce the systemic oxidative stress response.展开更多
As a development direction of urban rail transit system,the train autonomous circumambulate system(TACS)can operate in a safer,more efficient,and more economical mode.However,most urban rail transit systems transmit s...As a development direction of urban rail transit system,the train autonomous circumambulate system(TACS)can operate in a safer,more efficient,and more economical mode.However,most urban rail transit systems transmit signals through industrial,scientific,and medical(ISM)frequency bands or narrow frequency bands,which cannot meet the requirements of TACS.As a promising solution,the 5th generation(5G)mobile communication provides more services for the future urban rail transit systems,and covers the shortages of exiting communication technologies in terms of capacity and reliability.In this paper,we first briefly review the research status of current train control system and introduce its limitations.Next,we propose a novel network architecture,and present new technologies and requirements of the proposed architecture for TACS.Some potential challenges are then discussed to give insights for further research of TACS.展开更多
文摘Objective:To investigate the effect of high-intensity interval training on blood glucose control, adipocytokine secretion and oxidative stress response in patients with T2DM.Methods: A total of 92 patients with newly diagnosed T2DM who were treated in this hospital between July 2016 and July 2017 were divided into the control group (n=46) and HIIT group (n=46) by random number table method. Control group received conventional hypoglycemic therapy, HIIT group received hypoglycemic combined with high-intensity interval training therapy, and the intervention lasted for 3 months. The differences in blood glucose control, adipocytokine secretion and oxidative stress response were compared between the two groups before and after intervention.Results: Before intervention, the differences in blood glucose index levels in peripheral blood as well as the contents of adipocytokines and oxidative stress indexes in serum were not statistically significant between the two groups of patients. After 3 months of intervention, blood glucose indexes FPG, FINS and 2hPBG levels in peripheral blood of HIIT group were lower than those of control group;adipocytokine APN content in serum was higher than that of control group whereas LEP, Resistin and CHEM contents were lower than those of control group;oxidative stress indexes MDA and ROS contents in serum were lower than those of control group whereas T-AOC content was higher than that of control group. Conclusion: Routine hypoglycemic therapy combined with high-intensity interval training can further control the blood glucose levels, regulate the secretion of adipocytokines and reduce the systemic oxidative stress response.
基金This work was supported in part by the National Natural Science Foundation of China(U2001213,61971191 and 61661021)in part by the Beijing Natural Science Foundation under Grant L182018 and L201011,in part by National Key Research and Development Project(2020YFB1807204)+1 种基金in part by the open project of Shanghai Institute of Microsystem and Information Technology(20190910)in part by the Key project of Natural Science Foundation of Jiangxi Province(20202ACBL202006).
文摘As a development direction of urban rail transit system,the train autonomous circumambulate system(TACS)can operate in a safer,more efficient,and more economical mode.However,most urban rail transit systems transmit signals through industrial,scientific,and medical(ISM)frequency bands or narrow frequency bands,which cannot meet the requirements of TACS.As a promising solution,the 5th generation(5G)mobile communication provides more services for the future urban rail transit systems,and covers the shortages of exiting communication technologies in terms of capacity and reliability.In this paper,we first briefly review the research status of current train control system and introduce its limitations.Next,we propose a novel network architecture,and present new technologies and requirements of the proposed architecture for TACS.Some potential challenges are then discussed to give insights for further research of TACS.
