Objective:To investigate the clinical diagnostic significance of peripheral blood T-cell test(T-spot test)for tuberculosis(TB)infection combined with erythrocyte sedimentation rate(ESR)in pulmonary TB.Methods:41 patie...Objective:To investigate the clinical diagnostic significance of peripheral blood T-cell test(T-spot test)for tuberculosis(TB)infection combined with erythrocyte sedimentation rate(ESR)in pulmonary TB.Methods:41 patients with a clinical diagnosis of TB during hospitalization from January 2020 to April 2023 in our hospital were selected as the experimental group,and 45 patients without TB(bronchopneumonia patients)were selected as the control group.The diagnostic specificity,sensitivity,and accuracy of the T-spot TB test,ESR test,and the combined test of the two were calculated respectively.Results:The sensitivity,specificity,and accuracy of the T-spot TB test combined with ESR for the diagnosis of TB in the experimental group were significantly higher than the individual results of the T-spot TB test and ESR test alone(P<0.05).Conclusion:The T-spot TB test combined with the ESR test for TB diagnosis has greater clinical value than carrying out the tests individually.展开更多
目的探讨菌阳肺结核患者结核感染T细胞斑点试验(TB infection of T cells spot test,T-SPOT.TB)阴性病例的临床特点及其影响因素。方法选择2014年4月-2016年6月年龄≥16岁疑似肺结核收住我院的患者,于入院次日清晨采血送检T-SPOT.TB,并...目的探讨菌阳肺结核患者结核感染T细胞斑点试验(TB infection of T cells spot test,T-SPOT.TB)阴性病例的临床特点及其影响因素。方法选择2014年4月-2016年6月年龄≥16岁疑似肺结核收住我院的患者,于入院次日清晨采血送检T-SPOT.TB,并完善胸部CT、痰或气管镜刷检涂片抗酸染色、结核杆菌培养、血常规、T细胞亚群等。结果共募集201例菌阳病例,其中34例T-SPOT.TB结果阴性,其中抗酸杆菌涂片痰菌分级4+有9例(26%),≥4个肺野病损的有14例(41%),1~2个肺野病损+大量胸腔积液的有7例(21%),1个肺野病损+抗酸杆菌涂片痰菌分级1+的有8例(24%)。结论肺野严重受损,菌量负荷大、合并大量胸腔积液、轻症患者可能是菌阳肺结核患者T-SPOT.TB阴性的相关危险因素。展开更多
文摘Objective:To investigate the clinical diagnostic significance of peripheral blood T-cell test(T-spot test)for tuberculosis(TB)infection combined with erythrocyte sedimentation rate(ESR)in pulmonary TB.Methods:41 patients with a clinical diagnosis of TB during hospitalization from January 2020 to April 2023 in our hospital were selected as the experimental group,and 45 patients without TB(bronchopneumonia patients)were selected as the control group.The diagnostic specificity,sensitivity,and accuracy of the T-spot TB test,ESR test,and the combined test of the two were calculated respectively.Results:The sensitivity,specificity,and accuracy of the T-spot TB test combined with ESR for the diagnosis of TB in the experimental group were significantly higher than the individual results of the T-spot TB test and ESR test alone(P<0.05).Conclusion:The T-spot TB test combined with the ESR test for TB diagnosis has greater clinical value than carrying out the tests individually.
文摘目的探讨菌阳肺结核患者结核感染T细胞斑点试验(TB infection of T cells spot test,T-SPOT.TB)阴性病例的临床特点及其影响因素。方法选择2014年4月-2016年6月年龄≥16岁疑似肺结核收住我院的患者,于入院次日清晨采血送检T-SPOT.TB,并完善胸部CT、痰或气管镜刷检涂片抗酸染色、结核杆菌培养、血常规、T细胞亚群等。结果共募集201例菌阳病例,其中34例T-SPOT.TB结果阴性,其中抗酸杆菌涂片痰菌分级4+有9例(26%),≥4个肺野病损的有14例(41%),1~2个肺野病损+大量胸腔积液的有7例(21%),1个肺野病损+抗酸杆菌涂片痰菌分级1+的有8例(24%)。结论肺野严重受损,菌量负荷大、合并大量胸腔积液、轻症患者可能是菌阳肺结核患者T-SPOT.TB阴性的相关危险因素。
