Purpose: The object of this study was to compare intraocular pressure measurem ents obtained with the TGDc-01 “PRA”, a new, transpalpebral indentation tonom eter, with those from Goldmann applanation tonometry in no...Purpose: The object of this study was to compare intraocular pressure measurem ents obtained with the TGDc-01 “PRA”, a new, transpalpebral indentation tonom eter, with those from Goldmann applanation tonometry in normal and glaucomatous eyes. Methods and Patients: Forty healthy eyes and 185 eyes suffering from glauc oma were included in the study. For Goldmann tonometry three measurements and fo r the TGDc01 ten measurements were performed in a random order. All participants were placed in an upright position for all measurements. Results: In both group s a systematic increase of intraocular pressure was found within the TGDc-01-m easurements. Therefore, the first 3 measurements of each device were used for fu rther statistical analysis. No learning curve could be demonstrated for the TGDc -01-measurement with normal eyes. Within the group of normal eyes the mean 1OD obtained with the TGDc-01 was 1.84 mmHg lower than the mean 1OD obtained with Goldmann tonometry (two-sided Student’s t-test; P=0.003). In the group of gla ucomatous eyes, the mean intraocular pressure obtained with the Goldmann tonomet ry was 19.7 ±10.1 mmHg, with the TGDC-01 18.1 ±7.1 mmHg (coefficient of correlation r=0.64, P< 0.001). The mean standard deviatio n of intraocular pressure measurements with Goldmann tonometry was 1.2 ±.0.9 mm Hg, with the TGDc01 3.1 ±2.1 mmHg. TGDc-01-measurements over-estimated intra ocular pressure compared to Goldmann tonometry up to values of 16 mmHg and under estimated intraocular pressure at values over 16 mmHg. The difference increased by 5.5 mmHg per 10 mmHg Goldmann tonometry. The probability of success, defined as TGDc-01-recordings within ±3 mmHg of the Goldmann tonometry recordings, wa s less than 53 %between 5 and 20 mmHg and less than 30 %between 20 and 30 mmHg . Intraocular pressure (Goldmann tonometry) over 30 mmHg was always accompanied by TGDc-01-measurements lower than 3 mmHg. Conclusion: In eyes with elevated i ntraocular pressure, the TGDc-01 “PRA”significantly underestimated the intrao cular pressure measurement when compared to the gold standard, Goldmann tonometr y. At present, measurement of the intraocular pressure with the TGDc-01 should not be used for clinical management of patients with glaucoma.展开更多
Background: A recently developed digital tonometer for transpalpebral intraocu lar pressure (IOP) measurement, distributed by Corneal, Inc., allows the noninva sive measurement of IOP for screening purposes. Method: W...Background: A recently developed digital tonometer for transpalpebral intraocu lar pressure (IOP) measurement, distributed by Corneal, Inc., allows the noninva sive measurement of IOP for screening purposes. Method: We measured the IOP of 2 18 eyes in 109 patients of the Interdisciplinary Uveitis Center of the Universit y of Heidelberg with intact corneal epithelium. IOPs were measured first with th e TGDc-01 tonometer, and then by means of Goldmann tonometry. IOPs were recorde d by two independent examiners. The mean of three measurements obtained with the TGDc-01 was taken, whereas only one measurement was performed with the Goldman n tonometer. Results: The mean difference between the TGDc-01 and Goldmann measurementswas 3.7 mmHg. The standard deviation of the differences was ±4.06 mmHg. Thus measu rements acquired with the TGDc-01 may range 4.4 mmHg above or 11.8 mmHg below t he values given by Goldmann tonometry. Conclusion: The IOP values obtained with the TGDc-01 were in poor agreement with Goldmann tonometry. We found a higher v ariation as well as a bias towards lower IOP values with the TGDc-01. It is a q uestion of clinical judgement as to how far these deviating measurements can be accepted for screening purposes. Because the IOPs obtained with the TGDc-01 are generally lower and less accurate than those obtained with the Goldmann tonomet er we believe that the TGDc-01 is not a reliable tool for IOP measurement in cl inical routine.展开更多
文摘Purpose: The object of this study was to compare intraocular pressure measurem ents obtained with the TGDc-01 “PRA”, a new, transpalpebral indentation tonom eter, with those from Goldmann applanation tonometry in normal and glaucomatous eyes. Methods and Patients: Forty healthy eyes and 185 eyes suffering from glauc oma were included in the study. For Goldmann tonometry three measurements and fo r the TGDc01 ten measurements were performed in a random order. All participants were placed in an upright position for all measurements. Results: In both group s a systematic increase of intraocular pressure was found within the TGDc-01-m easurements. Therefore, the first 3 measurements of each device were used for fu rther statistical analysis. No learning curve could be demonstrated for the TGDc -01-measurement with normal eyes. Within the group of normal eyes the mean 1OD obtained with the TGDc-01 was 1.84 mmHg lower than the mean 1OD obtained with Goldmann tonometry (two-sided Student’s t-test; P=0.003). In the group of gla ucomatous eyes, the mean intraocular pressure obtained with the Goldmann tonomet ry was 19.7 ±10.1 mmHg, with the TGDC-01 18.1 ±7.1 mmHg (coefficient of correlation r=0.64, P< 0.001). The mean standard deviatio n of intraocular pressure measurements with Goldmann tonometry was 1.2 ±.0.9 mm Hg, with the TGDc01 3.1 ±2.1 mmHg. TGDc-01-measurements over-estimated intra ocular pressure compared to Goldmann tonometry up to values of 16 mmHg and under estimated intraocular pressure at values over 16 mmHg. The difference increased by 5.5 mmHg per 10 mmHg Goldmann tonometry. The probability of success, defined as TGDc-01-recordings within ±3 mmHg of the Goldmann tonometry recordings, wa s less than 53 %between 5 and 20 mmHg and less than 30 %between 20 and 30 mmHg . Intraocular pressure (Goldmann tonometry) over 30 mmHg was always accompanied by TGDc-01-measurements lower than 3 mmHg. Conclusion: In eyes with elevated i ntraocular pressure, the TGDc-01 “PRA”significantly underestimated the intrao cular pressure measurement when compared to the gold standard, Goldmann tonometr y. At present, measurement of the intraocular pressure with the TGDc-01 should not be used for clinical management of patients with glaucoma.
文摘Background: A recently developed digital tonometer for transpalpebral intraocu lar pressure (IOP) measurement, distributed by Corneal, Inc., allows the noninva sive measurement of IOP for screening purposes. Method: We measured the IOP of 2 18 eyes in 109 patients of the Interdisciplinary Uveitis Center of the Universit y of Heidelberg with intact corneal epithelium. IOPs were measured first with th e TGDc-01 tonometer, and then by means of Goldmann tonometry. IOPs were recorde d by two independent examiners. The mean of three measurements obtained with the TGDc-01 was taken, whereas only one measurement was performed with the Goldman n tonometer. Results: The mean difference between the TGDc-01 and Goldmann measurementswas 3.7 mmHg. The standard deviation of the differences was ±4.06 mmHg. Thus measu rements acquired with the TGDc-01 may range 4.4 mmHg above or 11.8 mmHg below t he values given by Goldmann tonometry. Conclusion: The IOP values obtained with the TGDc-01 were in poor agreement with Goldmann tonometry. We found a higher v ariation as well as a bias towards lower IOP values with the TGDc-01. It is a q uestion of clinical judgement as to how far these deviating measurements can be accepted for screening purposes. Because the IOPs obtained with the TGDc-01 are generally lower and less accurate than those obtained with the Goldmann tonomet er we believe that the TGDc-01 is not a reliable tool for IOP measurement in cl inical routine.
