Introduction: Prostate cancer is the leading urological cancer. It is the most common cancer in men over 50. Objective: To determine the epidemiological, diagnostic and therapeutic characteristics of prostate cancer i...Introduction: Prostate cancer is the leading urological cancer. It is the most common cancer in men over 50. Objective: To determine the epidemiological, diagnostic and therapeutic characteristics of prostate cancer in hospitals in the Thiès region. Patients and Methods: We conducted a descriptive study from January 1<sup>st</sup>, 2015 to December 31<sup>st</sup>, 2020. We included all cases of primary prostate cancer confirmed on histology. Results: We collected data on 318 cases of primary prostate cancer during the study period. Mean patient age was 72.7 years (Range: 49;94 years). Family history of prostate cancer was found in 22 patients (6.91%). The average consultation time was 18.6 months. The circumstances of discovery were dominated by obstructive voiding disorders (97.16%). Digital Rectal examination was suggestive in 55.40% of patients. PSA level was above 20 ng/ml in 76.7% of patients. Prostatic adenocarcinoma was the only histological type (100%). Localized cancer represented 7.2% and locally advanced cancer occurred in 36.5% of cases, while metastatic cancer accounted for 56.3%. Radical prostatectomy was performed in 3.18% of cases. Mortality rate was estimated at 8.50% after 1 year. Conclusion: Prostate cancer is the leading urological cancer in the Thies region. It is characterized by the predominance of locally advanced and metastatic forms.展开更多
Purpose: To describe the epidemiological, clinical and management characteristics of acute coronary syndromes (ACS) in Thies, Senegal. Methods: This was a prospective study that included consecutively from Octobe...Purpose: To describe the epidemiological, clinical and management characteristics of acute coronary syndromes (ACS) in Thies, Senegal. Methods: This was a prospective study that included consecutively from October 1<sup>st</sup>, 2018 to March 03<sup>rd</sup>, 2019, patients aged 18 years or older admitted for an ACS at the DIABCARMET department of the Saint Jean de Dieu Hospital in Thies. Results: Of the 516 patients admitted, 29 had ACS, the prevalence was 5.62%. The average age of the patients was 64.2 ± 11.6 years. Nineteen patients (65.5%) were male and 10 (34.5%) were female, the sex ratio was 1.91. The number of direct admissions was 18 (62%) versus 11 patients (38%) referred. The mode of transport was a private vehicle in 19 patients (65.5%), an ambulance in 7 patients (24.1%) and public transport in 3 patients (10.3%). STEMI (ST segment elevation myocardial infarction) was the most common presentation observed in 19 patients (65.5%). Fifteen patients (51.7%) were admitted before the 12<sup>th</sup> hour. Of the 19 patients with STEMI, 11 (57.9%) had arrived in hospital before the 12<sup>th</sup> hour and 10 patients had streptokinase thrombolysis. No patients received primary PCI. Ten patients (34.5%) had heart failure and five patients (17.2%) died during hospitalization. Conclusion: Delayed consultation and high mortality characterize ACS in Thies. Prevention must be the rule.展开更多
Introduction: Thyroid cancers are malignant cell proliferations developed at the expense of the thyroid gland, and which can spread from a distance. Most cancers appear in the form of anterior cervical swelling. Ultra...Introduction: Thyroid cancers are malignant cell proliferations developed at the expense of the thyroid gland, and which can spread from a distance. Most cancers appear in the form of anterior cervical swelling. Ultrasound and pathological examination allow the diagnosis of certainty. In Thiès, the studies carried out on thyroid cancers essentially focus on clinico-radiological and therapeutic aspects. We propose, through this study, to describe the epidemiological aspects and the morphological characteristics of thyroid cancers at Thiès Regional Hospital Center. Methodology: This is a retrospective, descriptive and analytical study conducted over a period of 3 years and 6 months, from January 2019 to June 2022. All patients with thyroid cancer confirmed by histological examination were included. Results: The patients who met the inclusion criteria were fourteen in number (14). The average age of patients was 40, 7 +/- 19 years old with extremes of 08 years and 75 years. Our series reports an 86% majority of women against 14% of men, with a sex ratio of 0.17. The isolated thyroid nodule was the most frequent mode of revelation of papillary thyroid cancers in our series, representing 54.6% of patients. The samplings received at the laboratory were essentially total thyroidectomy specimens. The tumor size varied between 1.5 cm and 14 cm. Papillary thyroid carcinoma was the most frequent histological type, with a frequency of 78.6%, followed by gallbladder carcinoma and squamous cell carcinoma. Conclusion: Thyroid cancers affect young subjects and are discovered at a late stage in our context.展开更多
The stereoselective synthesis of 2-chloro-4-substituted-phenyl-5,5-dimethyl-1,3,2-dioxaphosphorinan-2-(thi)ones is described. Only single trans-isomers were obtained when 1-substituted-phenyl-2,2-dimethyl-1,3-propaned...The stereoselective synthesis of 2-chloro-4-substituted-phenyl-5,5-dimethyl-1,3,2-dioxaphosphorinan-2-(thi)ones is described. Only single trans-isomers were obtained when 1-substituted-phenyl-2,2-dimethyl-1,3-propanediols (1) reacted with POCl3. But the stereoselectivity of cyclization reaction between (1) and PSCl3 depended greatly upon the reaction condition. The configurational assignments and the ratio of cis-/trans- diastereoisomers of the products were performed on the basis of (HNMR)-H-1, (PNMR)-P-31 and IR spectra and confirmed by X-ray diffraction analyses.展开更多
The aim of this work is to map the susceptibility of sites to landslides. To assess the susceptibility of the zone, GIS techniques were used. Susceptibility factors are selected and split into two groups: active and p...The aim of this work is to map the susceptibility of sites to landslides. To assess the susceptibility of the zone, GIS techniques were used. Susceptibility factors are selected and split into two groups: active and passive factors. Passive factors regroup all the intrinsic conditions existing on the field at all times. The active factors or triggering factors are present sporadically and are added to the passive factors to trigger a landslide. With the weighted overlay method using ArcGIS?, four scenarios have been developed. A first scenario where only passive factors are combined and three scenarios for which we have for each scenario the passive factors combined with an active factor. With these different scenarios, five levels of susceptibility are obtained in the zone. These levels range from very low to very high susceptibility. For the different scenarios, the results show that the zone consists mainly of very low to low susceptibility with at least 61% of the area, followed by moderate susceptibility (23.54% to 38.24%) and last land with high susceptibility to very high with less than 1% of the surface. Fields with high to very high susceptibility are located on the slopes of the hills. Among the active factors, only the rainfall significantly modifies the percentage of land susceptible to landslide but remains in the field of moderate susceptibility. The predicted susceptibilities are closer to the observed landslides around the Thies Cliff than to the Dias Horst.展开更多
The diversity of aquatic resources in Thi Nai Lagoon decreased due to the lack of harmonious use and integrated long-term planning on the use of living resources.There remained a lack of mechanisms and regulations for...The diversity of aquatic resources in Thi Nai Lagoon decreased due to the lack of harmonious use and integrated long-term planning on the use of living resources.There remained a lack of mechanisms and regulations for coordination of activities in the lagoon by Binh Dinh Provincial People’s Committee(PPC).The aim of the study was to investgate the aquatic species and water quality in Thi Nai Lagoon,Vietnam.Data were collected at 23 different points on Thi Nai Lagoon,with three replicates at each point.There were 106 species of fish presented on the lagoon and in different sizes,including 17 mollusc species and 15 crustaceans species.In the dry season,there were 167 phytoplankton species in five divisions,10 classes in 39 orders in 59 families including 77 genus.Zooplankton had eight chordata in 10 classes of 18 orders including 44 families,64 genus and 102 species.Arthropoda had the largest number of species,78 species,accounting for 76.5%of total species.In the rainy season,only 48 species of Arthropoda,Cnidaria,Annelida,Chaetognatha and Rotifer were affected and some were not encountered in the wet season,such as mollusca and chordata.While water quality variables were still good for aquaculture,within permitted limits of TCVN standard and criteria,there were still problems caused by production discharges and living activities of inhabitants around the lagoon,such as sedimentary matters.展开更多
Let F(x):R^m→R^m be an odd,continuously differentiable homogeneous map.The pa- per is devoted to the critical points of the generalized Rayleigh ratio||F(x)||_(l_q^m)/||x||_(l_p^m)and connected with some problems of ...Let F(x):R^m→R^m be an odd,continuously differentiable homogeneous map.The pa- per is devoted to the critical points of the generalized Rayleigh ratio||F(x)||_(l_q^m)/||x||_(l_p^m)and connected with some problems of the approximation theory.We find the lower bound for Kolmogorov n-width d_n(F(Bl_p^m),l_q^m).展开更多
文摘Introduction: Prostate cancer is the leading urological cancer. It is the most common cancer in men over 50. Objective: To determine the epidemiological, diagnostic and therapeutic characteristics of prostate cancer in hospitals in the Thiès region. Patients and Methods: We conducted a descriptive study from January 1<sup>st</sup>, 2015 to December 31<sup>st</sup>, 2020. We included all cases of primary prostate cancer confirmed on histology. Results: We collected data on 318 cases of primary prostate cancer during the study period. Mean patient age was 72.7 years (Range: 49;94 years). Family history of prostate cancer was found in 22 patients (6.91%). The average consultation time was 18.6 months. The circumstances of discovery were dominated by obstructive voiding disorders (97.16%). Digital Rectal examination was suggestive in 55.40% of patients. PSA level was above 20 ng/ml in 76.7% of patients. Prostatic adenocarcinoma was the only histological type (100%). Localized cancer represented 7.2% and locally advanced cancer occurred in 36.5% of cases, while metastatic cancer accounted for 56.3%. Radical prostatectomy was performed in 3.18% of cases. Mortality rate was estimated at 8.50% after 1 year. Conclusion: Prostate cancer is the leading urological cancer in the Thies region. It is characterized by the predominance of locally advanced and metastatic forms.
文摘Purpose: To describe the epidemiological, clinical and management characteristics of acute coronary syndromes (ACS) in Thies, Senegal. Methods: This was a prospective study that included consecutively from October 1<sup>st</sup>, 2018 to March 03<sup>rd</sup>, 2019, patients aged 18 years or older admitted for an ACS at the DIABCARMET department of the Saint Jean de Dieu Hospital in Thies. Results: Of the 516 patients admitted, 29 had ACS, the prevalence was 5.62%. The average age of the patients was 64.2 ± 11.6 years. Nineteen patients (65.5%) were male and 10 (34.5%) were female, the sex ratio was 1.91. The number of direct admissions was 18 (62%) versus 11 patients (38%) referred. The mode of transport was a private vehicle in 19 patients (65.5%), an ambulance in 7 patients (24.1%) and public transport in 3 patients (10.3%). STEMI (ST segment elevation myocardial infarction) was the most common presentation observed in 19 patients (65.5%). Fifteen patients (51.7%) were admitted before the 12<sup>th</sup> hour. Of the 19 patients with STEMI, 11 (57.9%) had arrived in hospital before the 12<sup>th</sup> hour and 10 patients had streptokinase thrombolysis. No patients received primary PCI. Ten patients (34.5%) had heart failure and five patients (17.2%) died during hospitalization. Conclusion: Delayed consultation and high mortality characterize ACS in Thies. Prevention must be the rule.
文摘Introduction: Thyroid cancers are malignant cell proliferations developed at the expense of the thyroid gland, and which can spread from a distance. Most cancers appear in the form of anterior cervical swelling. Ultrasound and pathological examination allow the diagnosis of certainty. In Thiès, the studies carried out on thyroid cancers essentially focus on clinico-radiological and therapeutic aspects. We propose, through this study, to describe the epidemiological aspects and the morphological characteristics of thyroid cancers at Thiès Regional Hospital Center. Methodology: This is a retrospective, descriptive and analytical study conducted over a period of 3 years and 6 months, from January 2019 to June 2022. All patients with thyroid cancer confirmed by histological examination were included. Results: The patients who met the inclusion criteria were fourteen in number (14). The average age of patients was 40, 7 +/- 19 years old with extremes of 08 years and 75 years. Our series reports an 86% majority of women against 14% of men, with a sex ratio of 0.17. The isolated thyroid nodule was the most frequent mode of revelation of papillary thyroid cancers in our series, representing 54.6% of patients. The samplings received at the laboratory were essentially total thyroidectomy specimens. The tumor size varied between 1.5 cm and 14 cm. Papillary thyroid carcinoma was the most frequent histological type, with a frequency of 78.6%, followed by gallbladder carcinoma and squamous cell carcinoma. Conclusion: Thyroid cancers affect young subjects and are discovered at a late stage in our context.
文摘The stereoselective synthesis of 2-chloro-4-substituted-phenyl-5,5-dimethyl-1,3,2-dioxaphosphorinan-2-(thi)ones is described. Only single trans-isomers were obtained when 1-substituted-phenyl-2,2-dimethyl-1,3-propanediols (1) reacted with POCl3. But the stereoselectivity of cyclization reaction between (1) and PSCl3 depended greatly upon the reaction condition. The configurational assignments and the ratio of cis-/trans- diastereoisomers of the products were performed on the basis of (HNMR)-H-1, (PNMR)-P-31 and IR spectra and confirmed by X-ray diffraction analyses.
文摘The aim of this work is to map the susceptibility of sites to landslides. To assess the susceptibility of the zone, GIS techniques were used. Susceptibility factors are selected and split into two groups: active and passive factors. Passive factors regroup all the intrinsic conditions existing on the field at all times. The active factors or triggering factors are present sporadically and are added to the passive factors to trigger a landslide. With the weighted overlay method using ArcGIS?, four scenarios have been developed. A first scenario where only passive factors are combined and three scenarios for which we have for each scenario the passive factors combined with an active factor. With these different scenarios, five levels of susceptibility are obtained in the zone. These levels range from very low to very high susceptibility. For the different scenarios, the results show that the zone consists mainly of very low to low susceptibility with at least 61% of the area, followed by moderate susceptibility (23.54% to 38.24%) and last land with high susceptibility to very high with less than 1% of the surface. Fields with high to very high susceptibility are located on the slopes of the hills. Among the active factors, only the rainfall significantly modifies the percentage of land susceptible to landslide but remains in the field of moderate susceptibility. The predicted susceptibilities are closer to the observed landslides around the Thies Cliff than to the Dias Horst.
文摘The diversity of aquatic resources in Thi Nai Lagoon decreased due to the lack of harmonious use and integrated long-term planning on the use of living resources.There remained a lack of mechanisms and regulations for coordination of activities in the lagoon by Binh Dinh Provincial People’s Committee(PPC).The aim of the study was to investgate the aquatic species and water quality in Thi Nai Lagoon,Vietnam.Data were collected at 23 different points on Thi Nai Lagoon,with three replicates at each point.There were 106 species of fish presented on the lagoon and in different sizes,including 17 mollusc species and 15 crustaceans species.In the dry season,there were 167 phytoplankton species in five divisions,10 classes in 39 orders in 59 families including 77 genus.Zooplankton had eight chordata in 10 classes of 18 orders including 44 families,64 genus and 102 species.Arthropoda had the largest number of species,78 species,accounting for 76.5%of total species.In the rainy season,only 48 species of Arthropoda,Cnidaria,Annelida,Chaetognatha and Rotifer were affected and some were not encountered in the wet season,such as mollusca and chordata.While water quality variables were still good for aquaculture,within permitted limits of TCVN standard and criteria,there were still problems caused by production discharges and living activities of inhabitants around the lagoon,such as sedimentary matters.
文摘Let F(x):R^m→R^m be an odd,continuously differentiable homogeneous map.The pa- per is devoted to the critical points of the generalized Rayleigh ratio||F(x)||_(l_q^m)/||x||_(l_p^m)and connected with some problems of the approximation theory.We find the lower bound for Kolmogorov n-width d_n(F(Bl_p^m),l_q^m).
