Background: Hepatocellular carcinoma(HCC) progresses fast and has a poor prognosis, but the growth rate in different TNM stages is not clear. The present study was to estimate the growth rate of HCC with different TNM...Background: Hepatocellular carcinoma(HCC) progresses fast and has a poor prognosis, but the growth rate in different TNM stages is not clear. The present study was to estimate the growth rate of HCC with different TNM stages at diagnosis. Methods: Baseline demographics and tumor characteristics were analyzed for 10145 patients in Surveillance, Epidemiology, and End Results(SEER) Program-registered HCC. Multiple linear regression models were used for age adjustment with patient race, sex, marital status, and HCC grade. Results: The age at diagnosis was younger in Caucasians and males. The adjusted average age of patients with stage I HCC was 65.26 years. The adjusted age of patients with stage II, IIIA, IIIB, and IIIC was-0.17,-0.25,-0.29, and-0.55 adjusted-year younger compared with patients with stage I HCC(all P < 0.001). The adjusted average age of patients with T1 was 65.26 years. The age adjustment was-0.17,-0.26, and-0.55 respectively(all P < 0.001) for T2, T3 or T4 tumors without distant metastases. Conclusions: These findings demonstrated that the more advanced the HCC stage at diagnosis, the younger the age at diagnosis and the faster the HCC growth from tumor occurrence.展开更多
目的分析基于PET/CT鉴别的肺癌患者TNM分期与情绪、睡眠及社会支持度的影响因素。方法选择2022年2月1日-2022年4月1日在本院进行PET/CT检查的100例肺癌患者作为研究对象,应用PET/CT检查肺癌并进行分期,使用HAMD和HAMA分别测量患者的抑...目的分析基于PET/CT鉴别的肺癌患者TNM分期与情绪、睡眠及社会支持度的影响因素。方法选择2022年2月1日-2022年4月1日在本院进行PET/CT检查的100例肺癌患者作为研究对象,应用PET/CT检查肺癌并进行分期,使用HAMD和HAMA分别测量患者的抑郁、焦虑等负性情绪因子,使用PSQI评估患者的睡眠质量情况,使用SSRS评估肺癌患者的社会支持度,并进行数据统计分析。结果三组TNM分期肺癌患者的抑郁、焦虑存在显著差异(P<0.05);睡眠质量间存在显著的差异(15.62±1.37 VS 20.81±2.34 VS 24.69±2.18,P<0.05);在社会支持度方面淋巴转移组、远处转移组和原发肺癌组间差异显著(P<0.05),差异具有统计学意义。结论本研究结果为后续制定更加合理的临床心理护理及治疗方案提供了参考依据。展开更多
基金This study was supported by grants from the Scientific Re-search Subject of Jiangsu Province Health Department(H201661)the Project of Invigorating Health Care through ScienceTech-nology and Education:Jiangsu Provincial Medical Youth Talent(QNRC2016331).
文摘Background: Hepatocellular carcinoma(HCC) progresses fast and has a poor prognosis, but the growth rate in different TNM stages is not clear. The present study was to estimate the growth rate of HCC with different TNM stages at diagnosis. Methods: Baseline demographics and tumor characteristics were analyzed for 10145 patients in Surveillance, Epidemiology, and End Results(SEER) Program-registered HCC. Multiple linear regression models were used for age adjustment with patient race, sex, marital status, and HCC grade. Results: The age at diagnosis was younger in Caucasians and males. The adjusted average age of patients with stage I HCC was 65.26 years. The adjusted age of patients with stage II, IIIA, IIIB, and IIIC was-0.17,-0.25,-0.29, and-0.55 adjusted-year younger compared with patients with stage I HCC(all P < 0.001). The adjusted average age of patients with T1 was 65.26 years. The age adjustment was-0.17,-0.26, and-0.55 respectively(all P < 0.001) for T2, T3 or T4 tumors without distant metastases. Conclusions: These findings demonstrated that the more advanced the HCC stage at diagnosis, the younger the age at diagnosis and the faster the HCC growth from tumor occurrence.
文摘目的分析基于PET/CT鉴别的肺癌患者TNM分期与情绪、睡眠及社会支持度的影响因素。方法选择2022年2月1日-2022年4月1日在本院进行PET/CT检查的100例肺癌患者作为研究对象,应用PET/CT检查肺癌并进行分期,使用HAMD和HAMA分别测量患者的抑郁、焦虑等负性情绪因子,使用PSQI评估患者的睡眠质量情况,使用SSRS评估肺癌患者的社会支持度,并进行数据统计分析。结果三组TNM分期肺癌患者的抑郁、焦虑存在显著差异(P<0.05);睡眠质量间存在显著的差异(15.62±1.37 VS 20.81±2.34 VS 24.69±2.18,P<0.05);在社会支持度方面淋巴转移组、远处转移组和原发肺癌组间差异显著(P<0.05),差异具有统计学意义。结论本研究结果为后续制定更加合理的临床心理护理及治疗方案提供了参考依据。
