Objective For understanding its clinical features and pathogenesis, six cases of Top ofthe Basilar syndrome (TOB-syndrome) were reported. Method The imaging results ofTOB-syndrome were analysed using CT scan and MR Im...Objective For understanding its clinical features and pathogenesis, six cases of Top ofthe Basilar syndrome (TOB-syndrome) were reported. Method The imaging results ofTOB-syndrome were analysed using CT scan and MR Imaging of six cases. Results CT scanand MR Imaging showed that the most important pathological features of TOB-syndrome issymmetrical papilionaceous infarction in bithalamus, whose pathogenesis is disturbance ofblood circulation at the crossing site of the right and left posterior cerebral arteries, and theright and left superior cerebellar arteries, and at the top end of the basilar artery within 2cmin diarnetes. The clinical rnanifestion is the sudden unconsciousness with the dilation of thepupils and the dismovement of the eyeballs as well as the behavior disorder. ConclusionTOB-syndrome often manifested infarction of bithalamus’ brainstem’ cerebellum. Theprognosis of the syndrome is poor, complete recovery is not common.展开更多
目的:探讨TOBS的最佳治疗方案。方法:对明确诊断的28例TOBS患者随机分为治疗组与对照组,各14例,治疗组入院后及时选用尿激酶150 IU加0.9%NaC l溶液100 m l快速静脉滴注,对照组按急性缺血性脑卒中予以治疗。观察两组患者治疗14d后血凝系...目的:探讨TOBS的最佳治疗方案。方法:对明确诊断的28例TOBS患者随机分为治疗组与对照组,各14例,治疗组入院后及时选用尿激酶150 IU加0.9%NaC l溶液100 m l快速静脉滴注,对照组按急性缺血性脑卒中予以治疗。观察两组患者治疗14d后血凝系统、神经功能缺损程度、生存率及出血性不良事件的差异。结果:治疗组经溶栓治疗后血小板计数(PLT)、凝血酶时间(PT)、活化部分凝血活酶时间(APTT)有差异,但均在正常范围,神经功能恢复及生存率明显高于对照组,且无全身性出血等不良事件。结论:符合溶栓治疗适应证的TOBS患者静脉溶栓治疗为首选方法。展开更多
基底动脉尖综合征（top of the basilar artery syndrome,TOBS）是由Caplan于1980年首先发现并命名,是基底动脉尖端缺血或闭塞所致血循环障碍,以丘脑、中脑、小脑、枕叶、颞叶损害为主的一组临床综合征。由于该病发病凶险,症状复杂,易...基底动脉尖综合征（top of the basilar artery syndrome,TOBS）是由Caplan于1980年首先发现并命名,是基底动脉尖端缺血或闭塞所致血循环障碍,以丘脑、中脑、小脑、枕叶、颞叶损害为主的一组临床综合征。由于该病发病凶险,症状复杂,易被误诊、漏诊,且多预后不良,故发病早期尽早诊断、治疗显得尤为重要。现将本院2009-04—2013-01收治的20例TOBS患者分析如下。展开更多
文摘Objective For understanding its clinical features and pathogenesis, six cases of Top ofthe Basilar syndrome (TOB-syndrome) were reported. Method The imaging results ofTOB-syndrome were analysed using CT scan and MR Imaging of six cases. Results CT scanand MR Imaging showed that the most important pathological features of TOB-syndrome issymmetrical papilionaceous infarction in bithalamus, whose pathogenesis is disturbance ofblood circulation at the crossing site of the right and left posterior cerebral arteries, and theright and left superior cerebellar arteries, and at the top end of the basilar artery within 2cmin diarnetes. The clinical rnanifestion is the sudden unconsciousness with the dilation of thepupils and the dismovement of the eyeballs as well as the behavior disorder. ConclusionTOB-syndrome often manifested infarction of bithalamus’ brainstem’ cerebellum. Theprognosis of the syndrome is poor, complete recovery is not common.
文摘目的:探讨TOBS的最佳治疗方案。方法:对明确诊断的28例TOBS患者随机分为治疗组与对照组,各14例,治疗组入院后及时选用尿激酶150 IU加0.9%NaC l溶液100 m l快速静脉滴注,对照组按急性缺血性脑卒中予以治疗。观察两组患者治疗14d后血凝系统、神经功能缺损程度、生存率及出血性不良事件的差异。结果:治疗组经溶栓治疗后血小板计数(PLT)、凝血酶时间(PT)、活化部分凝血活酶时间(APTT)有差异,但均在正常范围,神经功能恢复及生存率明显高于对照组,且无全身性出血等不良事件。结论:符合溶栓治疗适应证的TOBS患者静脉溶栓治疗为首选方法。
文摘基底动脉尖综合征（top of the basilar artery syndrome,TOBS）是由Caplan于1980年首先发现并命名,是基底动脉尖端缺血或闭塞所致血循环障碍,以丘脑、中脑、小脑、枕叶、颞叶损害为主的一组临床综合征。由于该病发病凶险,症状复杂,易被误诊、漏诊,且多预后不良,故发病早期尽早诊断、治疗显得尤为重要。现将本院2009-04—2013-01收治的20例TOBS患者分析如下。
