Domain-domain interactions are important clues to inferring protein-protein interactions. Although about 8 000 domain-domain interactions are discovered so far,they are just the tip of the iceberg. Because domains are...Domain-domain interactions are important clues to inferring protein-protein interactions. Although about 8 000 domain-domain interactions are discovered so far,they are just the tip of the iceberg. Because domains are conservative and commonplace in proteins,domain-domain interactions are discovered based on pairs of domains which significantly co-exist in proteins. Meanwhile,it is realized that:( 1) domain-domain interactions may exist within the same proteins or across different proteins;( 2) only the domain-domain interactions across different proteins can mediate interactions between proteins;( 3) domains have biases to interact with other domains. And then,a novel method is put forward to construct protein-protein interaction network by using domain-domain interactions. The method is validated by experiments and compared with the state- of-art methods in the field. The experimental results suggest that the method is reasonable and effectiveness on constructing Protein-protein interactions network.展开更多
A new algorithm for iterative reconstruction is suggested.It is named simple self-correlative algebraic reconstruction technique (SSART).With numerical simulation experiments,SSART was applied in reconstructing a non-...A new algorithm for iterative reconstruction is suggested.It is named simple self-correlative algebraic reconstruction technique (SSART).With numerical simulation experiments,SSART was applied in reconstructing a non-ideal-bordered field in order to test its reconstructive effect.For contrast,three current representative algebraic reconstruction(ARTs) including basic ART,simultaneous ART (SART) and modified SART (MSART) were simulated simultaneously.The calculated results and reconstructive accuracy are discussed with three kinds of error indexes,namely mean-square error (MSE),absolute value error (AVE) and peak error (PE).As the results,the indexes of reconstructive accuracy are much improved by the proposed SSART.The MSE and PE have been decreased by 63.6% on the order of magnitude 10-4 and 88.9% on the order of magnitude 0-2,respectively,compared to that of ART.It is concluded that SSART is one of the most super iterative reconstructing techniques.展开更多
Quantum digital signature is the quantum scenario of classical digital signature.It makes use of quantum effects to provide unconditionally secure signature.We first present a prototype of quantum signature scheme usi...Quantum digital signature is the quantum scenario of classical digital signature.It makes use of quantum effects to provide unconditionally secure signature.We first present a prototype of quantum signature scheme using single photons and then discuss its extensions.The most important property of the proposed scheme is that it is not necessary for the scheme to use entangled states.The security of the scheme is based on quantum key distribution and quantum one-time pad proved as unconditionally secure.The present scheme is efficient in that it needs only single photons and von Neumann measurement.We also show a quantum circuit for the scheme.展开更多
基金Sponsored by the National Natural Science Foundation of China(Grant No.61271346,61571163,61532014,91335112 and 61402132)the Fundamental Research Funds for the Central Universities(Grant No.DB13AB02)
文摘Domain-domain interactions are important clues to inferring protein-protein interactions. Although about 8 000 domain-domain interactions are discovered so far,they are just the tip of the iceberg. Because domains are conservative and commonplace in proteins,domain-domain interactions are discovered based on pairs of domains which significantly co-exist in proteins. Meanwhile,it is realized that:( 1) domain-domain interactions may exist within the same proteins or across different proteins;( 2) only the domain-domain interactions across different proteins can mediate interactions between proteins;( 3) domains have biases to interact with other domains. And then,a novel method is put forward to construct protein-protein interaction network by using domain-domain interactions. The method is validated by experiments and compared with the state- of-art methods in the field. The experimental results suggest that the method is reasonable and effectiveness on constructing Protein-protein interactions network.
基金This project was supported by China Postdoctoral Science Foun-dation(2004036121) the National Natural Science Foundation ofChina(10404022) Education Bureau of Shandong province(J04A63)
文摘A new algorithm for iterative reconstruction is suggested.It is named simple self-correlative algebraic reconstruction technique (SSART).With numerical simulation experiments,SSART was applied in reconstructing a non-ideal-bordered field in order to test its reconstructive effect.For contrast,three current representative algebraic reconstruction(ARTs) including basic ART,simultaneous ART (SART) and modified SART (MSART) were simulated simultaneously.The calculated results and reconstructive accuracy are discussed with three kinds of error indexes,namely mean-square error (MSE),absolute value error (AVE) and peak error (PE).As the results,the indexes of reconstructive accuracy are much improved by the proposed SSART.The MSE and PE have been decreased by 63.6% on the order of magnitude 10-4 and 88.9% on the order of magnitude 0-2,respectively,compared to that of ART.It is concluded that SSART is one of the most super iterative reconstructing techniques.
基金Supported by the National Natural Science Foundation of Chinaunder Grant No.60472032
文摘Quantum digital signature is the quantum scenario of classical digital signature.It makes use of quantum effects to provide unconditionally secure signature.We first present a prototype of quantum signature scheme using single photons and then discuss its extensions.The most important property of the proposed scheme is that it is not necessary for the scheme to use entangled states.The security of the scheme is based on quantum key distribution and quantum one-time pad proved as unconditionally secure.The present scheme is efficient in that it needs only single photons and von Neumann measurement.We also show a quantum circuit for the scheme.
