滑坡易发性评价是滑坡灾害防治的重要手段之一,而不合理的滑坡负样本会影响滑坡易发性评价,从而影响到滑坡灾害的防治,因此提供一种合理的负样本选取方法变得尤为关键。以西藏米林市的古滑坡为例,选择高程、坡度、坡向、坡位、距道路距...滑坡易发性评价是滑坡灾害防治的重要手段之一,而不合理的滑坡负样本会影响滑坡易发性评价,从而影响到滑坡灾害的防治,因此提供一种合理的负样本选取方法变得尤为关键。以西藏米林市的古滑坡为例,选择高程、坡度、坡向、坡位、距道路距离、距断层距离、距水系距离、地形起伏度、地层岩性、土地利用类型10类环境因子,使用Relief算法计算环境因子的贡献值并依据贡献值优化选择环境因子;基于环境因子优化的目标空间外向化采样法(target space exteriorization sampling,简称TSES)选择负样本,作为性能优异的随机森林模型的输入变量;之后结合优化的环境因子和正或负样本预测米林市的滑坡易发性,并用混淆矩阵和ROC曲线评价构建模型的性能。为检验环境因子优化的TSES法的有效性和先进性,采用耦合信息量法和TSES法选择滑坡负样本并构建随机森林模型,与环境因子优化的TSES法构建的随机森林模型进行对比研究。结果表明,环境因子优化的TSES法构建的随机森林模型的评价效果较好,其ACC为93.7%、AUC为0.987,均高于耦合信息量、TSES法构成的模型。环境因子优化的TSES法能够提高模型的精度,解决多因子作为约束条件取样中因子选取的问题,为滑坡易发性评价采集负样本提供了新的思路。展开更多
A Taylor series expansion(TSE) based design for minimum mean-square error(MMSE) and QR decomposition(QRD) of multi-input and multi-output(MIMO) systems is proposed based on application specific instruction set process...A Taylor series expansion(TSE) based design for minimum mean-square error(MMSE) and QR decomposition(QRD) of multi-input and multi-output(MIMO) systems is proposed based on application specific instruction set processor(ASIP), which uses TSE algorithm instead of resource-consuming reciprocal and reciprocal square root(RSR) operations.The aim is to give a high performance implementation for MMSE and QRD in one programmable platform simultaneously.Furthermore, instruction set architecture(ISA) and the allocation of data paths in single instruction multiple data-very long instruction word(SIMD-VLIW) architecture are provided, offering more data parallelism and instruction parallelism for different dimension matrices and operation types.Meanwhile, multiple level numerical precision can be achieved with flexible table size and expansion order in TSE ISA.The ASIP has been implemented to a 28 nm CMOS process and frequency reaches 800 MHz.Experimental results show that the proposed design provides perfect numerical precision within the fixed bit-width of the ASIP, higher matrix processing rate better than the requirements of 5G system and more rate-area efficiency comparable with ASIC implementations.展开更多
Objective To expatiate dynamic changes in hamsters infected with scrapie strain 263K, to observe the presence and aggravation of various forms of PrP and PrPSc during incubation period, and to probe primarily the rela...Objective To expatiate dynamic changes in hamsters infected with scrapie strain 263K, to observe the presence and aggravation of various forms of PrP and PrPSc during incubation period, and to probe primarily the relationship between the onset of clinic manifestations and the presence of different PrPSc forms. Methods Hamster-adapted scrapie strain 263K was intracerebrally inoculated into hamsters. Different forms of PrP and PrPSc were monitored dynamically by Western blot and immuno-histochemical assays. The presence of scrapie-associated fibril (SAF) was assayed by electron microscopy analysis (EM) and immune-golden EM. Results PrPSc was initially detected in the brain tissues of the animals in 20 days post-inoculation by immunohistochemistry and 40 days with Western blot. Quantitative evaluations revealed that the amounts of PrP and PrPSc in brain tissues increased along with the incubation. Several high and low molecular masses of PrP were seen in the brains of the long-life span infected animals. Deglycosylation assays identified that the truncated PrP in the infected brains showed similar glycosylation patterns as the full-length PrP. The presence of short fragments was seemed to relate with the onset of clinical conditions. Conclusion These results indicate that infectious agents exist and accumulate in central nerve system prior to the onset of the illness. Various molecular patterns of PrPSc may indwell in brain tissues during the infection.展开更多
文摘滑坡易发性评价是滑坡灾害防治的重要手段之一,而不合理的滑坡负样本会影响滑坡易发性评价,从而影响到滑坡灾害的防治,因此提供一种合理的负样本选取方法变得尤为关键。以西藏米林市的古滑坡为例,选择高程、坡度、坡向、坡位、距道路距离、距断层距离、距水系距离、地形起伏度、地层岩性、土地利用类型10类环境因子,使用Relief算法计算环境因子的贡献值并依据贡献值优化选择环境因子;基于环境因子优化的目标空间外向化采样法(target space exteriorization sampling,简称TSES)选择负样本,作为性能优异的随机森林模型的输入变量;之后结合优化的环境因子和正或负样本预测米林市的滑坡易发性,并用混淆矩阵和ROC曲线评价构建模型的性能。为检验环境因子优化的TSES法的有效性和先进性,采用耦合信息量法和TSES法选择滑坡负样本并构建随机森林模型,与环境因子优化的TSES法构建的随机森林模型进行对比研究。结果表明,环境因子优化的TSES法构建的随机森林模型的评价效果较好,其ACC为93.7%、AUC为0.987,均高于耦合信息量、TSES法构成的模型。环境因子优化的TSES法能够提高模型的精度,解决多因子作为约束条件取样中因子选取的问题,为滑坡易发性评价采集负样本提供了新的思路。
基金Supported by the Industrial Internet Innovation and Development Project of Ministry of Industry and Information Technology (No.GHBJ2004)。
文摘A Taylor series expansion(TSE) based design for minimum mean-square error(MMSE) and QR decomposition(QRD) of multi-input and multi-output(MIMO) systems is proposed based on application specific instruction set processor(ASIP), which uses TSE algorithm instead of resource-consuming reciprocal and reciprocal square root(RSR) operations.The aim is to give a high performance implementation for MMSE and QRD in one programmable platform simultaneously.Furthermore, instruction set architecture(ISA) and the allocation of data paths in single instruction multiple data-very long instruction word(SIMD-VLIW) architecture are provided, offering more data parallelism and instruction parallelism for different dimension matrices and operation types.Meanwhile, multiple level numerical precision can be achieved with flexible table size and expansion order in TSE ISA.The ASIP has been implemented to a 28 nm CMOS process and frequency reaches 800 MHz.Experimental results show that the proposed design provides perfect numerical precision within the fixed bit-width of the ASIP, higher matrix processing rate better than the requirements of 5G system and more rate-area efficiency comparable with ASIC implementations.
基金This work was supported by the National Natural Science Foundation of China, No. 39928018, 30070038 and 30130070, National High-tech Research Development Program (863 Program), No. 2001AA215391, and EU Project QLRT, No. 200001441.
文摘Objective To expatiate dynamic changes in hamsters infected with scrapie strain 263K, to observe the presence and aggravation of various forms of PrP and PrPSc during incubation period, and to probe primarily the relationship between the onset of clinic manifestations and the presence of different PrPSc forms. Methods Hamster-adapted scrapie strain 263K was intracerebrally inoculated into hamsters. Different forms of PrP and PrPSc were monitored dynamically by Western blot and immuno-histochemical assays. The presence of scrapie-associated fibril (SAF) was assayed by electron microscopy analysis (EM) and immune-golden EM. Results PrPSc was initially detected in the brain tissues of the animals in 20 days post-inoculation by immunohistochemistry and 40 days with Western blot. Quantitative evaluations revealed that the amounts of PrP and PrPSc in brain tissues increased along with the incubation. Several high and low molecular masses of PrP were seen in the brains of the long-life span infected animals. Deglycosylation assays identified that the truncated PrP in the infected brains showed similar glycosylation patterns as the full-length PrP. The presence of short fragments was seemed to relate with the onset of clinical conditions. Conclusion These results indicate that infectious agents exist and accumulate in central nerve system prior to the onset of the illness. Various molecular patterns of PrPSc may indwell in brain tissues during the infection.
