The bare LiFePO4 and LiFePO4/C composites with network structure were prepared by solid-state reaction. The crystalline structures, morphologies and specific surface areas of the materials were investigated by X-ray d...The bare LiFePO4 and LiFePO4/C composites with network structure were prepared by solid-state reaction. The crystalline structures, morphologies and specific surface areas of the materials were investigated by X-ray diffractometry(XRD), scanning electron microscopy(SEM) and multi-point brunauer emmett and teller(BET) method. The results show that the LiFePO4/C composite with the best network structure is obtained by adding 10% phenolic resin carbon. Its electronic conductivity increases to 2.86×10-2 S/cm. It possesses the highest specific surface area of 115.65 m2/g, which exhibits the highest discharge specific capacity of 164.33 mA·h/g at C/10 rate and 149.12 mA·h/g at 1 C rate. The discharge capacity is completely recovered when C/10 rate is applied again.展开更多
BACKGROUND Hepatitis C virus(HCV)infection progresses through various phases,starting with inflammation and ending with hepatocellular carcinoma.There are several invasive and non-invasive methods to diagnose chronic ...BACKGROUND Hepatitis C virus(HCV)infection progresses through various phases,starting with inflammation and ending with hepatocellular carcinoma.There are several invasive and non-invasive methods to diagnose chronic HCV infection.The invasive methods have their benefits but are linked to morbidity and complications.Thus,it is important to analyze the potential of non-invasive methods as an alternative.Shear wave elastography(SWE)is a non-invasive imaging tool widely validated in clinical and research studies as a surrogate marker of liver fibrosis.Liver fibrosis determination by invasive liver biopsy and non-invasive SWE agree closely in clinical studies and therefore both are gold standards.AIM To analyzed the diagnostic efficacy of non-invasive indices[serum fibronectin,aspartate aminotransferase to platelet ratio index(APRI),alanine aminotransferase ratio(AAR),and fibrosis-4(FIB-4)]in relation to SWE.We have used an Artificial Intelligence method to predict the severity of liver fibrosis and uncover the complex relationship between non-invasive indices and fibrosis severity.METHODS We have conducted a hospital-based study considering 100 untreated patients detected as HCV positive using a quantitative Real-Time Polymerase Chain Reaction assay.We performed statistical and probabilistic analyses to determine the relationship between non-invasive indices and the severity of fibrosis.We also used standard diagnostic methods to measure the diagnostic accuracy for all the subjects.RESULTS The results of our study showed that fibronectin is a highly accurate diagnostic tool for predicting fibrosis stages(mild,moderate,and severe).This was based on its sensitivity(100%,92.2%,96.2%),specificity(96%,100%,98.6%),Youden’s index(0.960,0.922,0.948),area under receiver operating characteristic curve(0.999,0.993,0.922),and Likelihood test(LR+>10 and LR-<0.1).Additionally,our Bayesian Network analysis revealed that fibronectin(>200),AAR(>1),APRI(>3),and FIB-4(>4)were all strongly associated with patients who had severe fibrosis,with a 100% probability.CONCLUSION We have found a strong correlation between fibronectin and liver fibrosis progression in HCV patients.Additionally,we observed that the severity of liver fibrosis increases with an increase in the non-invasive indices that we investigated.展开更多
Tai’an City is rich in tourism resources,and there are many A-class tourist attractions.Based on the functions and characteristics of geographic information system(GIS),as well as the spatial distribution characteris...Tai’an City is rich in tourism resources,and there are many A-class tourist attractions.Based on the functions and characteristics of geographic information system(GIS),as well as the spatial distribution characteristics and distribution structure of tourist attractions,the research methods of nearest-neighbor distance,connectivity,accessibility and closeness analysis are used to analyze road traffi c distribution between tourist attractions in Tai’an City.①The R value of the nearest-neighbor point is 0.27,which proves that tourist attractions in Tai’an City are in the state of clustering,and the spatial distance of tourist attractions in clustering area is small.②Theβindex andγindex of connectivity are 1.42 and 0.58,respectively,indicating that the traffi c network connectivity between tourist attractions is low,there is no dense traffi c network,and the optimal combination of tourism resources in tourist attractions is not high.③The accessibility index Ai is 37.68 km,indicating that the accessibility is low and the traffi c between tourist attractions is not perfect.The research results will provide the reference for scientifi c,systematic and objective comprehensive evaluation of existing A-class scenic areas and traffi c conditions in Tai’an City.展开更多
The Tianlian 1-03 satellite, the third geosynchronous data relay satellite of China, was successfully launched into space on a LM-3C launch vehicle from the Xichang Satellite Launch Center at 23:43 Beijing time on Jul...The Tianlian 1-03 satellite, the third geosynchronous data relay satellite of China, was successfully launched into space on a LM-3C launch vehicle from the Xichang Satellite Launch Center at 23:43 Beijing time on July 25. Twenty-six minutes after the liftoff, the satellite展开更多
基金Project(50672024) supported by the National Natural Science Foundation of ChinaProject(06FJ2006) supported by the Applied Basic Research of Hunan Province, China
文摘The bare LiFePO4 and LiFePO4/C composites with network structure were prepared by solid-state reaction. The crystalline structures, morphologies and specific surface areas of the materials were investigated by X-ray diffractometry(XRD), scanning electron microscopy(SEM) and multi-point brunauer emmett and teller(BET) method. The results show that the LiFePO4/C composite with the best network structure is obtained by adding 10% phenolic resin carbon. Its electronic conductivity increases to 2.86×10-2 S/cm. It possesses the highest specific surface area of 115.65 m2/g, which exhibits the highest discharge specific capacity of 164.33 mA·h/g at C/10 rate and 149.12 mA·h/g at 1 C rate. The discharge capacity is completely recovered when C/10 rate is applied again.
文摘BACKGROUND Hepatitis C virus(HCV)infection progresses through various phases,starting with inflammation and ending with hepatocellular carcinoma.There are several invasive and non-invasive methods to diagnose chronic HCV infection.The invasive methods have their benefits but are linked to morbidity and complications.Thus,it is important to analyze the potential of non-invasive methods as an alternative.Shear wave elastography(SWE)is a non-invasive imaging tool widely validated in clinical and research studies as a surrogate marker of liver fibrosis.Liver fibrosis determination by invasive liver biopsy and non-invasive SWE agree closely in clinical studies and therefore both are gold standards.AIM To analyzed the diagnostic efficacy of non-invasive indices[serum fibronectin,aspartate aminotransferase to platelet ratio index(APRI),alanine aminotransferase ratio(AAR),and fibrosis-4(FIB-4)]in relation to SWE.We have used an Artificial Intelligence method to predict the severity of liver fibrosis and uncover the complex relationship between non-invasive indices and fibrosis severity.METHODS We have conducted a hospital-based study considering 100 untreated patients detected as HCV positive using a quantitative Real-Time Polymerase Chain Reaction assay.We performed statistical and probabilistic analyses to determine the relationship between non-invasive indices and the severity of fibrosis.We also used standard diagnostic methods to measure the diagnostic accuracy for all the subjects.RESULTS The results of our study showed that fibronectin is a highly accurate diagnostic tool for predicting fibrosis stages(mild,moderate,and severe).This was based on its sensitivity(100%,92.2%,96.2%),specificity(96%,100%,98.6%),Youden’s index(0.960,0.922,0.948),area under receiver operating characteristic curve(0.999,0.993,0.922),and Likelihood test(LR+>10 and LR-<0.1).Additionally,our Bayesian Network analysis revealed that fibronectin(>200),AAR(>1),APRI(>3),and FIB-4(>4)were all strongly associated with patients who had severe fibrosis,with a 100% probability.CONCLUSION We have found a strong correlation between fibronectin and liver fibrosis progression in HCV patients.Additionally,we observed that the severity of liver fibrosis increases with an increase in the non-invasive indices that we investigated.
基金Natural Science Foundation of Shandong Province,China(ZR2019MD031)Philosophy and Social Science Planning Project of Tai’an City(2020skx035).
文摘Tai’an City is rich in tourism resources,and there are many A-class tourist attractions.Based on the functions and characteristics of geographic information system(GIS),as well as the spatial distribution characteristics and distribution structure of tourist attractions,the research methods of nearest-neighbor distance,connectivity,accessibility and closeness analysis are used to analyze road traffi c distribution between tourist attractions in Tai’an City.①The R value of the nearest-neighbor point is 0.27,which proves that tourist attractions in Tai’an City are in the state of clustering,and the spatial distance of tourist attractions in clustering area is small.②Theβindex andγindex of connectivity are 1.42 and 0.58,respectively,indicating that the traffi c network connectivity between tourist attractions is low,there is no dense traffi c network,and the optimal combination of tourism resources in tourist attractions is not high.③The accessibility index Ai is 37.68 km,indicating that the accessibility is low and the traffi c between tourist attractions is not perfect.The research results will provide the reference for scientifi c,systematic and objective comprehensive evaluation of existing A-class scenic areas and traffi c conditions in Tai’an City.
文摘The Tianlian 1-03 satellite, the third geosynchronous data relay satellite of China, was successfully launched into space on a LM-3C launch vehicle from the Xichang Satellite Launch Center at 23:43 Beijing time on July 25. Twenty-six minutes after the liftoff, the satellite