BACKGROUND Tailgut cysts are defined as congenital cysts that develop in the rectosacral space from the residue of the primitive tail.As a congenital disease,caudal cysts are very rare,and their canceration is even ra...BACKGROUND Tailgut cysts are defined as congenital cysts that develop in the rectosacral space from the residue of the primitive tail.As a congenital disease,caudal cysts are very rare,and their canceration is even rarer,which makes the disease prone to misdiagnosis and delayed treatment.We describe a case of caudal cyst with adenocarcinogenesis and summarize in detail the characteristics of cases with analytical value reported since 1990.CASE SUMMARY A 35-year-old woman found a mass in her lower abdomen 2 mo ago.She was asymptomatic at that time and was not treated because of the coronavirus disease 2019 pandemic.Two weeks ago,the patient developed abdominal distension and right waist discomfort and came to our hospital.Except for the high level of serum carcinoembryonic antigen,the medical history and laboratory tests were not remarkable.Magnetic resonance imaging showed a well-defined,slightly lobulated cystic-solid mass with a straight diameter of approximately 10 cm×9 cm in the presacral space,slightly high signal intensity on T2-weighted imaging,and moderate signal intensity on T1-weighted imaging.The mass was completely removed by laparoscopic surgery.Histopathological examination showed that the lesion was an intestinal mucinous adenocarcinoma,and the multidisciplinary team decided to implement postoperative chemotherapy.The patient recovered well,the tumor marker levels returned to normal,and tumor-free survival has been achieved thus far.CONCLUSION The case and literature summary can help clinicians and researchers develop appropriate examination and therapeutic methods for diagnosis and treatment of this rare disease.展开更多
Tailgut cyst is a rare congenital cystic lesion arising from the remnants of the embryonic postanal gut. It occurs exclusively within the retrorectal space and rarely in the perirenal area or in the subcutaneous tissu...Tailgut cyst is a rare congenital cystic lesion arising from the remnants of the embryonic postanal gut. It occurs exclusively within the retrorectal space and rarely in the perirenal area or in the subcutaneous tissue. A prerectal and retrovesical location of tailgut cyst is extremely rare. To the best of our knowledge, only three cases have been reported in the English literature. We experienced an unusual case of tailgut cyst developed in the prerectal and retrovesical space in a 14-year-old boy. Abdominal computed tomography demonstrated a prerectal cyst which was located at the anterolateral portion to the rectum. The cyst contained yellowish inspissated mucoid material. Microscopically, the cyst was lined by squamous, columnar, cuboidal and transitional epithelia and the wall was fibrotic with dispersed smooth muscle cells. Although tailgut cyst arising in prerectal area is extremely rare, its possibility should be considered in differential diagnosis of a prerectal and retrovesical cystic mass.展开更多
Retrorectal, developmental tail gut cysts, include dermoid cysts, rectal duplication cysts and retrorectal cyst-hamartomas. Retrorectal cyst-hamartomas （RCH） are derived from remnants of the tail gut, the most cauda...Retrorectal, developmental tail gut cysts, include dermoid cysts, rectal duplication cysts and retrorectal cyst-hamartomas. Retrorectal cyst-hamartomas （RCH） are derived from remnants of the tail gut, the most caudal part of the embryonic hincl gut, which normally involutes by the 8^th wk of embryonic development （3-8 mm stage）. They have specific radiological and histopathological features that distinguish them from other similar formations （dermoid cysts, enteric duplication cysts and teratomas）. We report a patient with adenosquamous carcinoma arising within RCH, who underwent complete resection of the cyst through anterior laparotomy, and reached complete （recurrencefree for 14 mo, so far） functional recovery. The cyst was incidentally discovered during hysterectomy 12 years ago. Diagnostic, therapeutic arid histopathological aspects of this rare case are discussed. The mentioned pedod between diagnosis and surgical treatment suggests that RCH, given enough time, can develop malignant degeneration, and should be resected at the time of diagnosis.展开更多
BACKGROUND Retrorectal hamartomas or tailgut cysts(TCs)are rare.In most cases,they are asymptomatic and benign;however,rarely,they undergo malignant transformation,mainly in the form of adenocarcinoma.CASE SUMMARY A 5...BACKGROUND Retrorectal hamartomas or tailgut cysts(TCs)are rare.In most cases,they are asymptomatic and benign;however,rarely,they undergo malignant transformation,mainly in the form of adenocarcinoma.CASE SUMMARY A 55-year-old woman presented to our hospital with lower back pain.On magnetic resonance imaging,a large pelvic mass was found,which was located on the right of the ischiorectal fossa,extending to the minor pelvis.The patient underwent extensive surgical resection of the lesion through the right buttock.Histological examination confirmed the diagnosis of a retrorectal mucinous adenocarcinoma originating from a TC.Surgical resection of the tumour was complete,and the patient recovered without complications.The pilonidal sinus was then excised.One year later,semi-annual positron emission tomographycomputed tomography and magnetic resonance imaging scans did not reveal any evidence of local recurrence or metastatic disease.CONCLUSION Preoperative recognition,histological diagnosis,and treatment of TCs pose significant challenges.In addition,the possibility of developing invasive mucinous adenocarcinoma,although rare,should be considered.展开更多
BACKGROUND Tailgut cyst is a congenital enterogenous cyst that rarely undergoes malignant transformation.Its clinical manifestations mainly correlate to the mass effect caused by the development of cysts and the infec...BACKGROUND Tailgut cyst is a congenital enterogenous cyst that rarely undergoes malignant transformation.Its clinical manifestations mainly correlate to the mass effect caused by the development of cysts and the infections that originate from these.Furthermore,the complete resection of this cyst is curative.We report our diagnostic and treatment experience with one case of malignant transformation of a perianal tailgut cyst,which was initially misdiagnosed as perianal abscess.CASE SUMMARY A 72-year-old woman visited our institution with complaints of a refractory nonhealing lesion on the right hip,which repeatedly broke and suppurated for more than 70 years,and aggravated in 4 mo.The patient was given a diagnosis of refractory perianal abscess with repeated incision and drainage procedures.Computed tomography of the pelvic cavity revealed a giant perianal cyst.Subsequent biopsy revealed a tumor with moderate-to-severe glandular epithelial dysplasia,and suggested that this was derived from the developmental cysts in the posterior rectal space.After further clarifying the nature and extent of the tumor by magnetic resonance imaging,total cystic resection was performed.Postoperative histopathological examination confirmed the malignancy,dictating the investigators to add postoperative chemotherapy to the treatment regimen.CONCLUSION The malignant transformation of perianal tailgut cysts is very uncommon,and this should be differentiated from perianal abscess.Complete surgical removal is curative,and postoperative pathology may determine the necessity of additional postoperative chemotherapy or radiotherapy,which may be beneficial for preventing local recurrence and metastasis.展开更多
Retrorectal cystic hamartomas are rare congenital lesions that can undergo malignant transformation, and adenocarcinoma is the most frequently described histological type. The authors describe a case of a 53-year-old ...Retrorectal cystic hamartomas are rare congenital lesions that can undergo malignant transformation, and adenocarcinoma is the most frequently described histological type. The authors describe a case of a 53-year-old female patient with a localized well-differentiated adenocarcinoma that developed in a retrorectal cystic hamartoma. The patient was submitted to surgery (a Kraske procedure), with an R1 resection, followed by adjuvant radio-chemotherapy. After 23 months of follow up, the patient remains free from disease recurrence. Given the rarity of this entity, this case allows us to reflect on the differential diagnosis, therapeutic approach and patients’ follow-up.展开更多
文摘BACKGROUND Tailgut cysts are defined as congenital cysts that develop in the rectosacral space from the residue of the primitive tail.As a congenital disease,caudal cysts are very rare,and their canceration is even rarer,which makes the disease prone to misdiagnosis and delayed treatment.We describe a case of caudal cyst with adenocarcinogenesis and summarize in detail the characteristics of cases with analytical value reported since 1990.CASE SUMMARY A 35-year-old woman found a mass in her lower abdomen 2 mo ago.She was asymptomatic at that time and was not treated because of the coronavirus disease 2019 pandemic.Two weeks ago,the patient developed abdominal distension and right waist discomfort and came to our hospital.Except for the high level of serum carcinoembryonic antigen,the medical history and laboratory tests were not remarkable.Magnetic resonance imaging showed a well-defined,slightly lobulated cystic-solid mass with a straight diameter of approximately 10 cm×9 cm in the presacral space,slightly high signal intensity on T2-weighted imaging,and moderate signal intensity on T1-weighted imaging.The mass was completely removed by laparoscopic surgery.Histopathological examination showed that the lesion was an intestinal mucinous adenocarcinoma,and the multidisciplinary team decided to implement postoperative chemotherapy.The patient recovered well,the tumor marker levels returned to normal,and tumor-free survival has been achieved thus far.CONCLUSION The case and literature summary can help clinicians and researchers develop appropriate examination and therapeutic methods for diagnosis and treatment of this rare disease.
文摘Tailgut cyst is a rare congenital cystic lesion arising from the remnants of the embryonic postanal gut. It occurs exclusively within the retrorectal space and rarely in the perirenal area or in the subcutaneous tissue. A prerectal and retrovesical location of tailgut cyst is extremely rare. To the best of our knowledge, only three cases have been reported in the English literature. We experienced an unusual case of tailgut cyst developed in the prerectal and retrovesical space in a 14-year-old boy. Abdominal computed tomography demonstrated a prerectal cyst which was located at the anterolateral portion to the rectum. The cyst contained yellowish inspissated mucoid material. Microscopically, the cyst was lined by squamous, columnar, cuboidal and transitional epithelia and the wall was fibrotic with dispersed smooth muscle cells. Although tailgut cyst arising in prerectal area is extremely rare, its possibility should be considered in differential diagnosis of a prerectal and retrovesical cystic mass.
文摘Retrorectal, developmental tail gut cysts, include dermoid cysts, rectal duplication cysts and retrorectal cyst-hamartomas. Retrorectal cyst-hamartomas （RCH） are derived from remnants of the tail gut, the most caudal part of the embryonic hincl gut, which normally involutes by the 8^th wk of embryonic development （3-8 mm stage）. They have specific radiological and histopathological features that distinguish them from other similar formations （dermoid cysts, enteric duplication cysts and teratomas）. We report a patient with adenosquamous carcinoma arising within RCH, who underwent complete resection of the cyst through anterior laparotomy, and reached complete （recurrencefree for 14 mo, so far） functional recovery. The cyst was incidentally discovered during hysterectomy 12 years ago. Diagnostic, therapeutic arid histopathological aspects of this rare case are discussed. The mentioned pedod between diagnosis and surgical treatment suggests that RCH, given enough time, can develop malignant degeneration, and should be resected at the time of diagnosis.
文摘BACKGROUND Retrorectal hamartomas or tailgut cysts(TCs)are rare.In most cases,they are asymptomatic and benign;however,rarely,they undergo malignant transformation,mainly in the form of adenocarcinoma.CASE SUMMARY A 55-year-old woman presented to our hospital with lower back pain.On magnetic resonance imaging,a large pelvic mass was found,which was located on the right of the ischiorectal fossa,extending to the minor pelvis.The patient underwent extensive surgical resection of the lesion through the right buttock.Histological examination confirmed the diagnosis of a retrorectal mucinous adenocarcinoma originating from a TC.Surgical resection of the tumour was complete,and the patient recovered without complications.The pilonidal sinus was then excised.One year later,semi-annual positron emission tomographycomputed tomography and magnetic resonance imaging scans did not reveal any evidence of local recurrence or metastatic disease.CONCLUSION Preoperative recognition,histological diagnosis,and treatment of TCs pose significant challenges.In addition,the possibility of developing invasive mucinous adenocarcinoma,although rare,should be considered.
文摘BACKGROUND Tailgut cyst is a congenital enterogenous cyst that rarely undergoes malignant transformation.Its clinical manifestations mainly correlate to the mass effect caused by the development of cysts and the infections that originate from these.Furthermore,the complete resection of this cyst is curative.We report our diagnostic and treatment experience with one case of malignant transformation of a perianal tailgut cyst,which was initially misdiagnosed as perianal abscess.CASE SUMMARY A 72-year-old woman visited our institution with complaints of a refractory nonhealing lesion on the right hip,which repeatedly broke and suppurated for more than 70 years,and aggravated in 4 mo.The patient was given a diagnosis of refractory perianal abscess with repeated incision and drainage procedures.Computed tomography of the pelvic cavity revealed a giant perianal cyst.Subsequent biopsy revealed a tumor with moderate-to-severe glandular epithelial dysplasia,and suggested that this was derived from the developmental cysts in the posterior rectal space.After further clarifying the nature and extent of the tumor by magnetic resonance imaging,total cystic resection was performed.Postoperative histopathological examination confirmed the malignancy,dictating the investigators to add postoperative chemotherapy to the treatment regimen.CONCLUSION The malignant transformation of perianal tailgut cysts is very uncommon,and this should be differentiated from perianal abscess.Complete surgical removal is curative,and postoperative pathology may determine the necessity of additional postoperative chemotherapy or radiotherapy,which may be beneficial for preventing local recurrence and metastasis.
文摘Retrorectal cystic hamartomas are rare congenital lesions that can undergo malignant transformation, and adenocarcinoma is the most frequently described histological type. The authors describe a case of a 53-year-old female patient with a localized well-differentiated adenocarcinoma that developed in a retrorectal cystic hamartoma. The patient was submitted to surgery (a Kraske procedure), with an R1 resection, followed by adjuvant radio-chemotherapy. After 23 months of follow up, the patient remains free from disease recurrence. Given the rarity of this entity, this case allows us to reflect on the differential diagnosis, therapeutic approach and patients’ follow-up.
