Objective: To study the clinical effect of Taozhi Zhipu Mixture(桃蛭枳朴合剂, TZM) in preventing postoperative intestinal adhesion. Methods: The total of 396 patients who had received abdominal operation were randomly...Objective: To study the clinical effect of Taozhi Zhipu Mixture(桃蛭枳朴合剂, TZM) in preventing postoperative intestinal adhesion. Methods: The total of 396 patients who had received abdominal operation were randomly divided into the treated group (188 cases) and the control group (208 cases). Same treatment was given to both groups except that the treated group received TZM orally or via nasogastric tube. The time of borborygmus recovering and first passing of flatus defecation after operation was recorded. Patients’ gastro intestinal motility was observed by isotope tracing with I 131 capsule. The frequency and intensity of borborygmus were measured by a tracer. All patients had been followed up for 2-3 years. Results: The recovery of borborygmus, the first passing of flatus defecation were much earlier, the I 131 capsule passed gastro intestinal tract more quickly, and the tracer showed higher frequency and intensity of borborygmus in the treated group than those in the control group. Follow up study also showed the treated group was better than the control group in the non adhesion rate and the total effective rate ( P <0.05). Conclusion: TZM has good effect on stimulating postoperational gastro intestinal peristalsis and preventing the occurrence of postoperational intestinal adhesion.展开更多
文摘Objective: To study the clinical effect of Taozhi Zhipu Mixture(桃蛭枳朴合剂, TZM) in preventing postoperative intestinal adhesion. Methods: The total of 396 patients who had received abdominal operation were randomly divided into the treated group (188 cases) and the control group (208 cases). Same treatment was given to both groups except that the treated group received TZM orally or via nasogastric tube. The time of borborygmus recovering and first passing of flatus defecation after operation was recorded. Patients’ gastro intestinal motility was observed by isotope tracing with I 131 capsule. The frequency and intensity of borborygmus were measured by a tracer. All patients had been followed up for 2-3 years. Results: The recovery of borborygmus, the first passing of flatus defecation were much earlier, the I 131 capsule passed gastro intestinal tract more quickly, and the tracer showed higher frequency and intensity of borborygmus in the treated group than those in the control group. Follow up study also showed the treated group was better than the control group in the non adhesion rate and the total effective rate ( P <0.05). Conclusion: TZM has good effect on stimulating postoperational gastro intestinal peristalsis and preventing the occurrence of postoperational intestinal adhesion.