基于TARGET融合ARCS动机模型的应用统计学课程教学改革研究

学生的学习动机直接关系到课程教学目标的达成,激发学习动机是推动课程教学改革的应有之义。将TARGET和ARCS学习动机模型引入应用统计学课程教学,分析当前教学中存在的动机问题,提出有效激发学生动机的教学方案和实践策略,结果既可促进应用统计学课程教学质量提升,也可为其他相似课程教学设计提供参考借鉴。

A New RCS Statistical Model of Radar Target

In this paper, the drawbacks of conventional target fluctuation models used in radar target modeling are set out. It is usually difficult to statistically model a real target because there are very few parameters which can be used to approximate the probability density function (PDF) of a real target's radar cross section (RCS) in conventional target models. A new method of statistical modeling is suggested, according to which the first nth central moment of real target's RCS, combined with the Legendre orthogonal polynomials, is used to reconstruct the PDF of the target's RCS. The relationship between the coefficients of the Legendre polynomials and the central moments of RCS are deduced mathematically. Through a practical computing example, the error-of-fit is shown as a function of the orders of Legendre coefficients. By comparing the errors-of-fit caused by both the new model and the conventional models, it is concluded that the new nonparametric method for statistical modeling of radar targets is superior.

A Study on the Multi-Compartment Linear Circulation Pharmacokinetic Model for the Targeting Drug Delivery System

By analyzing the observed phenomena and the data collected in the study, a multi-compartment linear circulation model for targeting drug delivery system was developed and the function formulas of the drug concentration-time in blood and target organ by computing were figured out. The drug concentration-time curve for target organ can be plotted with reference to the data of drug concentration in blood according to the model. The pharmacokinetic parameters of the drug in target organ could also be obtained. The practicability of the model was further checked by the curves of drug concentration-time in blood and target organ(liver) of liver-targeting nanoparticles in animal tests. Based on the liver drug concentration-time curves calculated by the function formula of the drug in target organ, the pharmacokinetic behavior of the drug in target organ(liver) was analyzed by statistical moment, and its pharmacokinetic parameters in liver were obtained. It is suggested that the (relative targeting index( can be used for quantitative evaluation of the targeting drug delivery systems.

Analytical models for the penetration of semi-infinite targets by rigid,deformable and erosive long rods

A theoretical study is presented herein on the pen- etration of a semi-infinite target by a spherical-headed long rod for Yp 〉 S, where Yp is the penetrator strength and S is the static target resistance. For Yp 〉 S, depending upon initial impact velocity, there exist three types of penetration, namely, penetration by a rigid long rod, penetration by a deforming non-erosive long rod and penetration by an erosive long rod. If the impact velocity of the penetrator is higher than the hydrodynamic velocity （VH）, it will penetrate the target in an erosive mode; if the impact velocity lies between the hydrodynamic velocity （VH） and the rigid body velocity （VR）, it will penetrate the target in a deformable mode; if the impact velocity is less than the rigid body velocity （VR）, it will penetrate the target in a rigid mode. The critical conditions for the transition among these three penetration modes are proposed. It is demonstrated that the present model predictions correlate well with the experimental observations in terms of depth of penetration （DOP） and the critical transition conditions.

Establishing a rat model of spastic cerebral palsy by targeted ethanol injection

Spastic cerebral palsy is generally considered to result from cerebral cortical or pyramidal tract damage. Here, we precisely targeted the left pyramidal tract of 2-month-old Sprague-Dawley rats placed on a stereotaxic instrument under intraperitoneal anesthesia. Based on the rat brain stereotaxic map, a 1-mm hole was made 10 mm posterior to bregma and 0.8 mm left of sagittal suture. A microsyringe was inserted perpendicularly to the surface of the brain to a depth of 9.7 mm, and 15 wL of ethanol was slowly injected to establish a rat model of spastic cerebral palsy. After modeling, the rats appeared to have necrotic voids in the pyramidal tract and exhibited typical signs and symptoms of flexion spasms that lasted for a long period of time. These findings indicate that this is an effective and easy method of establishing a rat model of spastic cerebral palsy with good reproducibility. Ethanol as a chemical ablation agent specifically and thoroughly damages the py- ramidal tract, and therefore, the animals display flexion spasms, which are a typical symptom of the disease.

Ore prospecting model and targets for the Dashuigou tellurium deposit, Sichuan Province, China

The Dashuigou tellurium(Te) deposit in Shimian city, Sichuan Province is the only known independent Te ore deposit in China. Samples were collected by1/50,000 stream sediment survey and analyzed by inductively coupled plasma–mass spectrometry, X-ray fluorescence spectrometry, emission spectrometry, and atomic absorption spectroscopy. An ore prospecting model for the Dashuigou Te deposit was then established. In the Dashuigou area, bismuth(Bi), Te, and gold(Au) concentrations in stream sediment samples displayed weak-positive anomalies, while silver(Ag) displayed a weaknegative anomaly. Bi, Te, Ag, and Au anomalies are regarded as indicators of Te deposits; the greater the ratio of Te+Bi/Au+Ag, the larger the possibility of an independent tellurobismuthite deposit. The ratio calculated from our samples is 7.288. Five locations were identified for prospecting for Te minerals by this model, including the northern part of the Dashuigou Te deposit, Majiagou,Tizigou, southeastern Miaoping, and northern Baishuihe.These five regions are within the Dashuigou dome anticline, the exposed strata of which are controlled by tracing the tensile shear fracture; the metallogenic geological conditions and geochemical characteristics are the same as those of the known Dashuigou Te deposit. Already, Te–Bi veins have been found in some of these areas.

Design and comparison of minimal symmetric model-subset for maneuvering target tracking

Model-set is utilized in state estimation for maneuver- ing target tracking. Two minimal symmetric model-subsets are designed and investigated by moment matching method, which include hypersphere-symmetric model-subset and axis-symmetric model-subset, if system mode is a random variable and obeys certain probability distribution. They can be used as the fun- damental model-subset for multiple models estimation with fixed structure, variable structure and moving bank. The model-groups constructed by above designed subsets are given, which give the practical guidance for use of model-set in multiple models ap- proach with a variable structure. Simulation results show that the performances of two minimal model-set significantly outperform the corresponding model-sets with fixed spacing.

Heterogeneous performance analysis of the new model of CFAR detectors for partially-correlated χ~2-targets

To mitigate the deleterious effects of clutter and jammer, modern radars have adopted adaptive processing techniques such as constant false alarm rate(CFAR) detectors which are widely used to prevent clutter and noise interference from saturating the radar’s display and preventing targets from being obscured.This paper concerns with the detection analysis of the novel version of CFAR schemes(cell-averaging generalized trimmed-mean,CATM) in the presence of additional outlying targets other than the target under research. The spurious targets as well as the tested one are assumed to be fluctuating in accordance with the χ~2-model with two-degrees of freedom. In this situation, the processor performance is enclosed by the swerling models(SWI and SWII). Between these bounds, there is an important class of target fluctuation which is known as moderately fluctuating targets. The detection of this class has many practical applications. Structure of the CATM detector is described briefly. Detection performances for optimal, CAM, CA, trimmed-mean(TM) and ordered-statistic(OS) CFAR strategies have been analyzed and compared for desired probability of false alarm and determined size of the reference window. False alarm rate performance of these processors has been evaluated for different strengths of interfering signal and the effect of correlation among the target returns on the detection and false alarm performances has also been studied. Our numerical results show that, with a proper choice of trimming parameters,the novel model CAM presents an ideal detection performance outweighing that of the Neyman-Pearson detector on condition that the tested target obeys the SWII model in its fluctuation. Although the new models CAS and CAM can be treated as special cases of the CATM algorithm, their multi-target performance is modest even it has an enhancement relative to that of the classical CAcheme. Additionally, they fail to maintain the false alarm rate constant when the operating environment is of type target multiplicity. Moreover, the non-coherent integration of M pulses ameliorates the processor performance either it operates in homogeneous or multi-target environment.

Propofol Target-Controlled Infusion Modeling in Rabbits:Pharmacokinetic and Pharmacodynamic Analysis

This study aimed to establish a new propofol target-controlled infusion（TCI） model in animals so as to study the general anesthetic mechanism at multi-levels in vivo. Twenty Japanese white rabbits were enrolled and propofol（10 mg/kg） was administrated intravenously. Artery blood samples were collected at various time points after injection, and plasma concentrations of propofol were measured. Pharmacokinetic modeling was performed using Win Nonlin software. Propofol TCI within the acquired parameters integrated was conducted to achieve different anesthetic depths in rabbits, monitored by narcotrend. The pharmacodynamics was analyzed using a sigmoidal inhibitory maximal effect model for narcotrend index（NI） versus effect-site concentration. The results showed the pharmacokinetics of propofol in Japanese white rabbits was best described by a two-compartment model. The target plasma concentrations of propofol required at light anesthetic depth was 9.77±0.23 μg/m L, while 12.52±0.69 μg/m L at deep anesthetic depth. NI was 76.17±4.25 at light anesthetic depth, while 27.41±5.77 at deep anesthetic depth. The effect-site elimination rate constant（ke0） was 0.263/min, and the propofol dose required to achieve a 50% decrease in the NI value from baseline was 11.19 μg/m L（95% CI, 10.25–13.67）. Our results established a new propofol TCI animal model and proved the model controlled the anesthetic depth accurately and stably in rabbits. The study provides a powerful method for exploring general anesthetic mechanisms at different anesthetic depths in vivo.

A Fuzzy Adaptive Algorithm Based on“Current”Statistical Model for Maneuvering Target Tracking

The basic"current"statistical model and adaptive Kalman filter algorithm can not track a weakly maneuvering target precisely,though it has good estimate accuracy for strongly maneuvering target.In order to solve this problem,a novel nonlinear fuzzy membership function was presented to adjust the upper and lower limit of target acceleration adaptively,and then the validity of the new algorithm for feeblish maneuvering target was proved in theory.At last,the computer simulation experiments indicated that the new algorithm has a great advantage over the basic"current"statistical model and adaptive algorithm.

Research on Motion Attention Fusion Model-Based Video Target Detection and Extraction of Global Motion Scene

For target detection algorithm under global motion scene, this paper suggests a target detection algorithm based on motion attention fusion model. Firstly, the motion vector field is pre-processed by accumulation and median filter;Then, according to the temporal and spatial character of motion vector, the attention fusion model is defined, which is used to detect moving target;Lastly, the edge of video moving target is made exactly by morphologic operation and edge tracking algorithm. The experimental results of different global motion video sequences show the proposed algorithm has a better veracity and speedup than other algorithm.

Computer Model for Evaluating Multi-Target Tracking Algorithms

Public benchmark datasets have been widely used to evaluate multi-target tracking algorithms. Ideally, the benchmark datasets should include the video scenes of all scenarios that need to be tested. However, a limited amount of the currently available benchmark datasets does not comprehensively cover all necessary test scenarios. This limits the evaluation of multitarget tracking algorithms with various test scenarios. This paper introduced a computer simulation model that generates benchmark datasets for evaluating multi-target tracking algorithms with the complexity of multitarget tracking scenarios directly controlled by simulation inputs such as target birth and death rates, target movement, the rates of target merges and splits, target appearances, and image noise types and levels. The simulation model generated a simulated video and also provides the ground-truth target tracking for the simulated video, so the evaluation of multitarget tracking algorithms can be easily performed without any manual video annotation process. We demonstrated the use of the proposed simulation model for evaluating tracking-by-detection algorithms and filtering-based tracking algorithms.

Application of Incident Chain Model and Targeted Dissemination Technology in Early Warning System

In order to improve the accuracy and efficiency of early warning system, the incident chain model and the targeted dissemination technology are proposed in this paper. Firstly, the occurrence probability, affected area and duration of disaster are predicted with the incident chain model and GIS. According to prediction results, the early warning system can accurately deliver early warning information specifically to the affected areas through targeted dissemination. Moreover, dissemination performance can also be evaluated in real time after early warning information dissemination, so that everyone in the affected area can receive early warning information successfully. The incident chain model and the targeted dissemination technology presented in this study are of great significance for improving the information dissemination ability of early warning system.

Searching for Novel Targets to Control Wheat Head Blight Disease—I-Protein Identification, 3D Modeling and Virtual Screening

Fusarium head blight (FHB) is a destructive disease of wheat and other cereals. FHB occurs in Europe, North America and around the world causing significant losses in production and endangers human and animal health. In this article, we provide the strategic steps for the specific target selection for the phytopathogen system wheat-Fusarium graminearum. The economic impact of FHB leads to the need for innovation. Currently used fungicides have been shown to be effective over the years, but recently cereal infecting Fusaria have developed resistance. Our work presents a new perspective on target selection to allow the development of new fungicides. We developed an innovative approach combining both genomic analysis and molecular modeling to increase the discovery for new chemical compounds with both safety and low environmental impact. Our protein targets selection revealed 13 candidates with high specificity, essentiality and potentially assayable with a favorable accessibility to drug activity. Among them, three proteins: trichodiene synthase, endoglucanase-5 and ERG6 were selected for deeper structural analyses to identify new putative fungicides. Overall, the bioinformatics filtering for novel protein targets applied for agricultural purposes is a response to the demand for chemical crop protection. The availability of the genome, secretome and PHI-base allowed the enrichment of the search that combined experimental data in planta. The homology modeling and molecular dynamics simulations allowed the acquisition of three robust and stable conformers. From this step, approximately ten thousand compounds have been virtually screened against three candidates. Forty-five top-ranked compounds were selected from docking results as presenting better interactions and energy at the binding pockets and no toxicity. These compounds may act as inhibitors and lead to the development of new fungicides.

A NEW MODELING AND FILTERING APPROACH FOR TRACKING MANEUVERING TARGETS

A new modeling and filtering approach for tracking maneuvering targets is presented in thispaper.The approach,which makes optimal estimate for the model With the random variable possible,depends on random step modeling of target maneuvers.In the new model,the unknown targetacceleration is treated as a random variable and then estimated directly.A detector is designed tofind out the target maneuvers and the estimation algorithm will be restarted when the maneuvers oc-cur.Combination of three-dimention Kalman filter with a detector forms a tracker for maneuveringtargets.The new tracking scheme is easy to implement and its capability is illustrated in two trackingexamples in which the new approach is compared with Mooses’on the performance.

目标教学模式联合PBL教学法在中医耳鼻喉科临床教学中的作用及对其考核成绩的影响分析

目的探析目标教学模式联合问题式学习(Problem-Based Learning,PBL)教学法在中医耳鼻喉科临床教学中的应用价值。方法选取2022年8月—2023年8月福建中医药大学附属第二人民医院耳鼻喉科的52名实习医师为研究对象,依据组间信息均衡可比原则将其分为对照组和观察组,各26名。对照组应用常规教学方法,观察组应用目标教学模式联合PBL教学法,带教结束后对比两组考核成绩、实习医师综合能力以及带教满意度。结果观察组考核成绩、实习医师综合能力各项得分均高于对照组,差异有统计学意义(P均<0.05)。观察组激发学习兴趣、加深对课程的掌握程度以及对教学模式认同等5个方面评分均高于对照组,差异有统计学意义(P均<0.05)。结论目标教学模式联合PBL教学法对中医耳鼻喉科实习医师考核成绩、综合能力和带教满意度提升均可产生积极影响。

A Space-Time Reverberation Model for Moving Target Detection

In recent years,moving target detection methods based on low-rank and sparse matrix decomposition have been developed,and they have achieved good results.However,there is not enough interpretation to support the assumption that there is a high correlation among the reverberations after each transmitting pulse.In order to explain the correlation of reverberations,a new reverberation model is proposed from the perspective of scattering cells in this paper.The scattering cells are the subarea divided from the detection area.The energy fluctuation of a scattering cell with time and the influence of the neighboring cells are considered.Key parameters of the model were analyzed by numerical analysis,and the applicability of the model was verified by experimental analysis.The results showed that the model can be used for several simulations to evaluate the performance of moving target detection methods.

低空轻量级红外弱小目标检测算法

精准的红外弱小目标检测是实时监控、追踪、制导的关键;红外弱小目标存在检测难度高、误检高、漏检严重的问题。为了提高红外弱小目标检测算法的实时性和检测精度,提出了一种超轻量红外弱小目标检测算法SL-YOLO。首先,重设计下采样方案,针对红外图像特征信息调节网络架构,解决红外弱小目标特征梯度降低和特征消失问题;然后设计网络模型剪枝算法,实现剪枝算法与网络结构的融合,去除冗余参数,实现检测速度的提高;最后设计Varifocal-SIoU损失函数,在均衡正负样本与重叠损失的同时,对正样本进行加权处理,解决背景干扰问题。实验结果表明,在SIRST和IDSAT数据集下检测精度分别提高至96.4%、98.1%,模型体积和计算量可压缩至190 kB、0.9 GFLOPs,推理速度降至3 ms以下。与主流算法进行对比,改进后算法在检测精度、模型体积、计算量等方面均取得了不错的成绩。能够满足实时性检测需求。

一种基于目标与背景特征分离模型的高光谱目标检测修正算法

高光谱图像立方体数据可以提供成像场景中地物在可见光和近红外波长范围内的空间信息和地物属性诊断的光谱特征信息,在目标检测与识别方面拥有得天独厚的天然优势。然而,基于高光谱图像数据的目标检测也存在一定缺陷,如经典的高光谱目标检测算法仅利用光谱维度信息检测目标,检测模型要么对背景高维特征矩阵构建的准确度不足,要么对背景先验光谱特征的完备性要求较高,导致算法对不同复杂度的检测场景适应性不强。因此,基于计算复杂度较低、参数需求量较少且检测性能较为优异的经典多目标检测算法—多目标约束能量最小化(MCEM),提出了一种基于目标与背景环境特征分离模型的高光谱目标检测修正算法(R-MCEM)。首先,设计了一个与目标形状、尺寸相近的逐像元移动运算窗口,依次计算窗口中的每个像元与窗口内其他像元的光谱距离之和D1,像元与各类目标的光谱距离之和D2。其次,采用获得D1/D2最小值的像元替换窗口内的所有像元值。然后,自左向右、自上而下逐像元移动窗口,重复窗口内每一个像元与目标、背景像元的光谱距离运算,并确定窗口内与背景相似度最高、与目标相似度最低的像元。直到移动运算窗口遍历整个高光谱图像,大幅提升了基于目标与背景环境特征分离的背景高维特征矩阵准确度。分别设计了基于实测高光谱图像数据和模拟图像数据的修正检测算法性能验证试验,并采用三维操作特征曲线(3D ROC)结合目标与背景分离度(SDBT)开展修正算法的检测精度评估。试验结果表明,提出的修正算法有效减少了虚警率,提高了检测精度。基于实测数据的检测精度、目标与背景分离度由MCEM算法的0.937 7、 0.57提升到R-MCEM的0.993 5、 0.67,基于模拟数据的亚像元检测能力由MCEM的20%丰度提升到R-MCEM的15%丰度。

VIDEO MULTI-TARGET TRACKING BASED ON PROBABILISTIC GRAPHICAL MODEL

In the technique of video multi-target tracking,the common particle filter can not deal well with uncertain relations among multiple targets.To solve this problem,many researchers use data association method to reduce the multi-target uncertainty.However,the traditional data association method is difficult to track accurately when the target is occluded.To remove the occlusion in the video,combined with the theory of data association,this paper adopts the probabilistic graphical model for multi-target modeling and analysis of the targets relationship in the particle filter framework.Ex-perimental results show that the proposed algorithm can solve the occlusion problem better compared with the traditional algorithm.