This paper concluded the vegetation restoration technique system in the arid-hot valleys and studied the anti-erosion function, environmental function and biological diversity effects of vegetation restoration on the ...This paper concluded the vegetation restoration technique system in the arid-hot valleys and studied the anti-erosion function, environmental function and biological diversity effects of vegetation restoration on the ecosystem in the arid-hot valleys. The results showed that the soil erodibility decreased significantly after the vegetation restoration. The climate environment of the small watershed had a great improvement after the vegetation restoration, of which the temperature decreased, the humidity increased, the harsh environment of dry and hot in this region changed. The studies of the ecosystem biodiversity were mainly on the analysis of the relations between biodiversity and ecological function of the artificial ecological forest pattern and the natural enclosed treatment mode on the severely of degraded land. It could conclude that the natural enclosed treatment mode is helpful to the biodiversity of the ecosystem and the improvement and stability of the ecosystem, and Leucaena artificial forest restoration pattern reduced the species diversity but optimized the ecological function. Therefore, as to the severely and extremely severely degraded ecosystem in the arid-hot valleys, Leucaena pattern of gully control and natural enclosed treatment mode are the relatively optimal choices.展开更多
BACKGROUND The magnetic compression technique has been used to establish an animal model of tracheoesophageal fistula(TEF),but the commonly shaped magnets present limitations of poor homogeneity of TEF and poor model ...BACKGROUND The magnetic compression technique has been used to establish an animal model of tracheoesophageal fistula(TEF),but the commonly shaped magnets present limitations of poor homogeneity of TEF and poor model control.We designed a Tshaped magnet system to overcome these problems and verified its effectiveness via animal experiments.AIM To investigate the effectiveness of a T-shaped magnet system for establishing a TEF model in beagle dogs.METHODS Twelve beagles were randomly assigned to groups in which magnets of the Tshaped scheme(study group,n=6)or normal magnets(control group,n=6)were implanted into the trachea and esophagus separately under gastroscopy.Operation time,operation success rate,and accidental injury were recorded.After operation,the presence and timing of cough and the time of magnet shedding were observed.Dogs in the control group were euthanized after X-ray and gastroscopy to confirm establishment of TEFs after coughing,and gross specimens of TEFs were obtained.Dogs in the study group were euthanized after X-ray and gastroscopy 2 wk after surgery,and gross specimens were obtained.Fistula size was measured in all animals,and then harvested fistula specimens were examined by hematoxylin and eosin(HE)and Masson trichrome staining.RESULTS The operation success rate was 100%for both groups.Operation time did not differ between the study group(5.25 min±1.29 min)and the control group(4.75 min±1.70 min;P=0.331).No bleeding,perforation,or unplanned magnet attraction occurred in any animal during the operation.In the early postoperative period,all dogs ate freely and were generally in good condition.Dogs in the control group had severe cough after drinking water at 6-9 d after surgery.X-ray indicated that the magnets had entered the stomach,and gastroscopy showed TEF formation.Gross specimens of TEFs from the control group showed the formation of fistulas with a diameter of 4.94 mm±1.29 mm(range,3.52-6.56 mm).HE and Masson trichrome staining showed scar tissue formation and hierarchical structural disorder at the fistulas.Dogs in the study group did not exhibit obvious coughing after surgery.X-ray examination 2 wk after surgery indicated fixed magnet positioning,and gastroscopy showed no change in magnet positioning.The magnets were removed using a snare under endoscopy,and TEF was observed.Gross specimens showed well-formed fistulas with a diameter of 6.11 mm±0.16 mm(range,5.92-6.36 mm),which exceeded that in the control group(P<0.001).Scar formation was observed on the internal surface of fistulas by HE and Masson trichrome staining,and the structure was more regular than that in the control group.CONCLUSION Use of the modified T-shaped magnet scheme is safe and feasible for establishing TEF and can achieve a more stable and uniform fistula size compared with ordinary magnets.Most importantly,this model offers better controllability,which improves the flexibility of follow-up studies.展开更多
Forecasting travel demand requires a grasp of individual decision-making behavior.However,transport mode choice(TMC)is determined by personal and contextual factors that vary from person to person.Numerous characteris...Forecasting travel demand requires a grasp of individual decision-making behavior.However,transport mode choice(TMC)is determined by personal and contextual factors that vary from person to person.Numerous characteristics have a substantial impact on travel behavior(TB),which makes it important to take into account while studying transport options.Traditional statistical techniques frequently presume linear correlations,but real-world data rarely follows these presumptions,which may make it harder to grasp the complex interactions.Thorough systematic review was conducted to examine how machine learning(ML)approaches might successfully capture nonlinear correlations that conventional methods may ignore to overcome such challenges.An in-depth analysis of discrete choice models(DCM)and several ML algorithms,datasets,model validation strategies,and tuning techniques employed in previous research is carried out in the present study.Besides,the current review also summarizes DCM and ML models to predict TMC and recognize the determinants of TB in an urban area for different transport modes.The two primary goals of our study are to establish the present conceptual frameworks for the factors influencing the TMC for daily activities and to pinpoint methodological issues and limitations in previous research.With a total of 39 studies,our findings shed important light on the significance of considering factors that influence the TMC.The adjusted kernel algorithms and hyperparameter-optimized ML algorithms outperform the typical ML algorithms.RF(random forest),SVM(support vector machine),ANN(artificial neural network),and interpretable ML algorithms are the most widely used ML algorithms for the prediction of TMC where RF achieved an R2 of 0.95 and SVM achieved an accuracy of 93.18%;however,the adjusted kernel enhanced the accuracy of SVM 99.81%which shows that the interpretable algorithms outperformed the typical algorithms.The sensitivity analysis indicates that the most significant parameters influencing TMC are the age,total trip time,and the number of drivers.展开更多
The rapid evolution of wireless communication technologies has underscored the critical role of antennas in ensuring seamless connectivity.Antenna defects,ranging from manufacturing imperfections to environmental wear...The rapid evolution of wireless communication technologies has underscored the critical role of antennas in ensuring seamless connectivity.Antenna defects,ranging from manufacturing imperfections to environmental wear,pose significant challenges to the reliability and performance of communication systems.This review paper navigates the landscape of antenna defect detection,emphasizing the need for a nuanced understanding of various defect types and the associated challenges in visual detection.This review paper serves as a valuable resource for researchers,engineers,and practitioners engaged in the design and maintenance of communication systems.The insights presented here pave the way for enhanced reliability in antenna systems through targeted defect detection measures.In this study,a comprehensive literature analysis on computer vision algorithms that are employed in end-of-line visual inspection of antenna parts is presented.The PRISMA principles will be followed throughout the review,and its goals are to provide a summary of recent research,identify relevant computer vision techniques,and evaluate how effective these techniques are in discovering defects during inspections.It contains articles from scholarly journals as well as papers presented at conferences up until June 2023.This research utilized search phrases that were relevant,and papers were chosen based on whether or not they met certain inclusion and exclusion criteria.In this study,several different computer vision approaches,such as feature extraction and defect classification,are broken down and analyzed.Additionally,their applicability and performance are discussed.The review highlights the significance of utilizing a wide variety of datasets and measurement criteria.The findings of this study add to the existing body of knowledge and point researchers in the direction of promising new areas of investigation,such as real-time inspection systems and multispectral imaging.This review,on its whole,offers a complete study of computer vision approaches for quality control in antenna parts.It does so by providing helpful insights and drawing attention to areas that require additional exploration.展开更多
BACKGROUND Postoperative delirium,particularly prevalent in elderly patients after abdominal cancer surgery,presents significant challenges in clinical management.AIM To develop a synthetic minority oversampling techn...BACKGROUND Postoperative delirium,particularly prevalent in elderly patients after abdominal cancer surgery,presents significant challenges in clinical management.AIM To develop a synthetic minority oversampling technique(SMOTE)-based model for predicting postoperative delirium in elderly abdominal cancer patients.METHODS In this retrospective cohort study,we analyzed data from 611 elderly patients who underwent abdominal malignant tumor surgery at our hospital between September 2020 and October 2022.The incidence of postoperative delirium was recorded for 7 d post-surgery.Patients were divided into delirium and non-delirium groups based on the occurrence of postoperative delirium or not.A multivariate logistic regression model was used to identify risk factors and develop a predictive model for postoperative delirium.The SMOTE technique was applied to enhance the model by oversampling the delirium cases.The model’s predictive accuracy was then validated.RESULTS In our study involving 611 elderly patients with abdominal malignant tumors,multivariate logistic regression analysis identified significant risk factors for postoperative delirium.These included the Charlson comorbidity index,American Society of Anesthesiologists classification,history of cerebrovascular disease,surgical duration,perioperative blood transfusion,and postoperative pain score.The incidence rate of postoperative delirium in our study was 22.91%.The original predictive model(P1)exhibited an area under the receiver operating characteristic curve of 0.862.In comparison,the SMOTE-based logistic early warning model(P2),which utilized the SMOTE oversampling algorithm,showed a slightly lower but comparable area under the curve of 0.856,suggesting no significant difference in performance between the two predictive approaches.CONCLUSION This study confirms that the SMOTE-enhanced predictive model for postoperative delirium in elderly abdominal tumor patients shows performance equivalent to that of traditional methods,effectively addressing data imbalance.展开更多
Rechargeable battery cycling performance and related safety have been persistent concerns.It is crucial to decipher the capacity fading induced by electrode material failure via a range of techniques.Among these,synch...Rechargeable battery cycling performance and related safety have been persistent concerns.It is crucial to decipher the capacity fading induced by electrode material failure via a range of techniques.Among these,synchrotron-based X-ray techniques with high flux and brightness play a key role in understanding degradation mechanisms.In this comprehensive review,we summarize recent advancements in degra-dation modes and mechanisms that were revealed by synchrotron X-ray methodologies.Subsequently,an overview of X-ray absorption spectroscopy and X-ray scattering techniques is introduced for charac-terizing failure phenomena at local coordination atomic environment and long-range order crystal struc-ture scale,respectively.At last,we envision the future of exploring material failure mechanism.展开更多
Recently,researchers have shown increasing interest in combining more than one programming model into systems running on high performance computing systems(HPCs)to achieve exascale by applying parallelism at multiple ...Recently,researchers have shown increasing interest in combining more than one programming model into systems running on high performance computing systems(HPCs)to achieve exascale by applying parallelism at multiple levels.Combining different programming paradigms,such as Message Passing Interface(MPI),Open Multiple Processing(OpenMP),and Open Accelerators(OpenACC),can increase computation speed and improve performance.During the integration of multiple models,the probability of runtime errors increases,making their detection difficult,especially in the absence of testing techniques that can detect these errors.Numerous studies have been conducted to identify these errors,but no technique exists for detecting errors in three-level programming models.Despite the increasing research that integrates the three programming models,MPI,OpenMP,and OpenACC,a testing technology to detect runtime errors,such as deadlocks and race conditions,which can arise from this integration has not been developed.Therefore,this paper begins with a definition and explanation of runtime errors that result fromintegrating the three programming models that compilers cannot detect.For the first time,this paper presents a classification of operational errors that can result from the integration of the three models.This paper also proposes a parallel hybrid testing technique for detecting runtime errors in systems built in the C++programming language that uses the triple programming models MPI,OpenMP,and OpenACC.This hybrid technology combines static technology and dynamic technology,given that some errors can be detected using static techniques,whereas others can be detected using dynamic technology.The hybrid technique can detect more errors because it combines two distinct technologies.The proposed static technology detects a wide range of error types in less time,whereas a portion of the potential errors that may or may not occur depending on the 4502 CMC,2023,vol.74,no.2 operating environment are left to the dynamic technology,which completes the validation.展开更多
The myelin sheath is a lipoprotein-rich,multilayered structure capable of increasing conduction velocity in central and peripheral myelinated nerve fibers.Due to the complex structure and composition of myelin,various...The myelin sheath is a lipoprotein-rich,multilayered structure capable of increasing conduction velocity in central and peripheral myelinated nerve fibers.Due to the complex structure and composition of myelin,various histological techniques have been developed over the centuries to evaluate myelin under normal,pathological or experimental conditions.Today,methods to assess myelin integrity or content are key tools in both clinical diagnosis and neuroscience research.In this review,we provide an updated summary of the composition and structure of the myelin sheath and discuss some histological procedures,from tissue fixation and processing techniques to the most used and practical myelin histological staining methods.Considering the lipoprotein nature of myelin,the main features and technical details of the different available methods that can be used to evaluate the lipid or protein components of myelin are described,as well as the precise ultrastructural techniques.展开更多
The development of intestinal anastomosis techniques,including hand suturing,stapling,and compression anastomoses,has been a significant advancement in surgical practice.These methods aim to prevent leakage and minimi...The development of intestinal anastomosis techniques,including hand suturing,stapling,and compression anastomoses,has been a significant advancement in surgical practice.These methods aim to prevent leakage and minimize tissue fibrosis,which can lead to stricture formation.The healing process involves various phases:hemostasis and inflammation,proliferation,and remodeling.Mechanical staplers and sutures can cause inflammation and fibrosis due to the release of profibrotic chemokines.Compression anastomosis devices,including those made of nickel-titanium alloy,offer a minimally invasive option for various surgical challenges and have shown safety and efficacy.However,despite advancements,anastomotic techniques are evaluated based on leakage risk,with complications being a primary concern.Newer devices like Magnamosis use magnetic rings for compression anastomosis,demonstrating greater strength and patency compared to stapling.Magnetic technology is also being explored for other medical treatments.While there are promising results,particularly in animal models,the realworld application in humans is limited,and further research is needed to assess their safety and practicality.展开更多
While emerging technologies such as the Internet of Things(IoT)have many benefits,they also pose considerable security challenges that require innovative solutions,including those based on artificial intelligence(AI),...While emerging technologies such as the Internet of Things(IoT)have many benefits,they also pose considerable security challenges that require innovative solutions,including those based on artificial intelligence(AI),given that these techniques are increasingly being used by malicious actors to compromise IoT systems.Although an ample body of research focusing on conventional AI methods exists,there is a paucity of studies related to advanced statistical and optimization approaches aimed at enhancing security measures.To contribute to this nascent research stream,a novel AI-driven security system denoted as“AI2AI”is presented in this work.AI2AI employs AI techniques to enhance the performance and optimize security mechanisms within the IoT framework.We also introduce the Genetic Algorithm Anomaly Detection and Prevention Deep Neural Networks(GAADPSDNN)sys-tem that can be implemented to effectively identify,detect,and prevent cyberattacks targeting IoT devices.Notably,this system demonstrates adaptability to both federated and centralized learning environments,accommodating a wide array of IoT devices.Our evaluation of the GAADPSDNN system using the recently complied WUSTL-IIoT and Edge-IIoT datasets underscores its efficacy.Achieving an impressive overall accuracy of 98.18%on the Edge-IIoT dataset,the GAADPSDNN outperforms the standard deep neural network(DNN)classifier with 94.11%accuracy.Furthermore,with the proposed enhancements,the accuracy of the unoptimized random forest classifier(80.89%)is improved to 93.51%,while the overall accuracy(98.18%)surpasses the results(93.91%,94.67%,94.94%,and 94.96%)achieved when alternative systems based on diverse optimization techniques and the same dataset are employed.The proposed optimization techniques increase the effectiveness of the anomaly detection system by efficiently achieving high accuracy and reducing the computational load on IoT devices through the adaptive selection of active features.展开更多
Introducing IoT devices to healthcare fields has made it possible to remotely monitor patients’information and provide a proper diagnosis as needed,resulting in the Internet of Medical Things(IoMT).However,obtaining ...Introducing IoT devices to healthcare fields has made it possible to remotely monitor patients’information and provide a proper diagnosis as needed,resulting in the Internet of Medical Things(IoMT).However,obtaining good security features that ensure the integrity and confidentiality of patient’s information is a significant challenge.However,due to the computational resources being limited,an edge device may struggle to handle heavy detection tasks such as complex machine learning algorithms.Therefore,designing and developing a lightweight detection mechanism is crucial.To address the aforementioned challenges,a new lightweight IDS approach is developed to effectively combat a diverse range of cyberattacks in IoMT networks.The proposed anomaly-based IDS is divided into three steps:pre-processing,feature selection,and decision.In the pre-processing phase,data cleaning and normalization are performed.In the feature selection step,the proposed approach uses two data-driven kernel techniques:kernel principal component analysis and kernel partial least square techniques to reduce the dimension of extracted features and to ameliorate the detection results.Therefore,in decision step,in order to classify whether the traffic flow is normal or malicious the kernel extreme learning machine is used.To check the efficiency of the developed detection scheme,a modern IoMT dataset named WUSTL-EHMS-2020 is considered to evaluate and discuss the achieved results.The proposed method achieved 99.9%accuracy,99.8%specificity,100%Sensitivity,99.9 F-score.展开更多
The increasing number of security holes in the Internet of Things(IoT)networks creates a question about the reliability of existing network intrusion detection systems.This problem has led to the developing of a resea...The increasing number of security holes in the Internet of Things(IoT)networks creates a question about the reliability of existing network intrusion detection systems.This problem has led to the developing of a research area focused on improving network-based intrusion detection system(NIDS)technologies.According to the analysis of different businesses,most researchers focus on improving the classification results of NIDS datasets by combining machine learning and feature reduction techniques.However,these techniques are not suitable for every type of network.In light of this,whether the optimal algorithm and feature reduction techniques can be generalized across various datasets for IoT networks remains.The paper aims to analyze the methods used in this research and whether they can be generalized to other datasets.Six ML models were used in this study,namely,logistic regression(LR),decision trees(DT),Naive Bayes(NB),random forest(RF),K-nearest neighbors(KNN),and linear SVM.The primary detection algorithms used in this study,Principal Component(PCA)and Gini Impurity-Based Weighted Forest(GIWRF)evaluated against three global ToN-IoT datasets,UNSW-NB15,and Bot-IoT datasets.The optimal number of dimensions for each dataset was not studied by applying the PCA algorithm.It is stated in the paper that the selection of datasets affects the performance of the FE techniques and detection algorithms used.Increasing the efficiency of this research area requires a comprehensive standard feature set that can be used to improve quality over time.展开更多
In this era of post-COVID-19,humans are psychologically restricted to interact less with other humans.According to the world health organization(WHO),there are many scenarios where human interactions cause severe mult...In this era of post-COVID-19,humans are psychologically restricted to interact less with other humans.According to the world health organization(WHO),there are many scenarios where human interactions cause severe multiplication of viruses from human to human and spread worldwide.Most healthcare systems shifted to isolation during the pandemic and a very restricted work environment.Investigations were done to overcome the remedy,and the researcher developed different techniques and recommended solutions.Telepresence robot was the solution achieved by all industries to continue their operations but with almost zero physical interaction with other humans.It played a vital role in this perspective to help humans to perform daily routine tasks.Healthcare workers can use telepresence robots to interact with patients who visit the healthcare center for initial diagnosis for better healthcare system performance without direct interaction.The presented paper aims to compare different telepresence robots and their different controlling techniques to perform the needful in the respective scenario of healthcare environments.This paper comprehensively analyzes and reviews the applications of presented techniques to control different telepresence robots.However,our feature-wise analysis also points to specific technical,appropriate,and ethical challenges that remain to be solved.The proposed investigation summarizes the need for further multifaceted research on the design and impact of a telepresence robot for healthcare centers,building on new perceptions during the COVID-19 pandemic.展开更多
The combination of electrospinning and hot pressing,namely the electrospinning-hot pressing technique(EHPT),is an efficient and convenient method for preparing nanofibrous composite materials with good energy storage ...The combination of electrospinning and hot pressing,namely the electrospinning-hot pressing technique(EHPT),is an efficient and convenient method for preparing nanofibrous composite materials with good energy storage performance.The emerging composite membrane prepared by EHPT,which exhibits the advantages of large surface area,controllable morphology,and compact structure,has attracted immense attention.In this paper,the conduction mechanism of composite membranes in thermal and electrical energy storage and the performance enhancement method based on the fabrication process of EHPT are systematically discussed.Moreover,the state-of-the-art applications of composite membranes in these two fields are introduced.In particular,in the field of thermal energy storage,EHPT-prepared membranes have longitudinal and transverse nanofibers,which generate unique thermal conductivity pathways;also,these nanofibers offer enough space for the filling of functional materials.Moreover,EHPT-prepared membranes are beneficial in thermal management systems,building energy conservation,and electrical energy storage,e.g.,improving the electrochemical properties of the separators as well as their mechanical and thermal stability.The application of electrospinning-hot pressing membranes on capacitors,lithium-ion batteries(LIBs),fuel cells,sodium-ion batteries(SIBs),and hydrogen bromine flow batteries(HBFBs)still requires examination.In the future,EHPT is expected to make the field more exciting through its own technological breakthroughs or be combined with other technologies to produce intelligent materials.展开更多
Tyrosine kinase inhibitors(TKIs)have emerged as the first-line small molecule drugs in many cancer therapies,exerting their effects by impeding aberrant cell growth and proliferation through the modulation of tyrosine...Tyrosine kinase inhibitors(TKIs)have emerged as the first-line small molecule drugs in many cancer therapies,exerting their effects by impeding aberrant cell growth and proliferation through the modulation of tyrosine kinase-mediated signaling pathways.However,there exists a substantial inter-individual variability in the concentrations of certain TKIs and their metabolites,which may render patients with compromised immune function susceptible to diverse infections despite receiving theoretically efficacious anticancer treatments,alongside other potential side effects or adverse reactions.Therefore,an urgent need exists for an up-to-date review concerning the biological matrices relevant to bioanalysis and the sampling methods,clinical pharmacokinetics,and therapeutic drug monitoring of different TKIs.This paper provides a comprehensive overview of the advancements in pretreatment methods,such as protein precipitation(PPT),liquid-liquid extraction(LLE),solid-phase extraction(SPE),micro-SPE(μ-SPE),magnetic SPE(MSPE),and vortex-assisted dispersive SPE(VA-DSPE)achieved since 2017.It also highlights the latest analysis techniques such as newly developed high performance liquid chromatography(HPLC)and high-resolution mass spectrometry(HRMS)methods,capillary electrophoresis(CE),gas chromatography(GC),supercritical fluid chromatography(SFC)procedures,surface plasmon resonance(SPR)assays as well as novel nanoprobes-based biosensing techniques.In addition,a comparison is made between the advantages and disadvantages of different approaches while presenting critical challenges and prospects in pharmacokinetic studies and therapeutic drug monitoring.展开更多
Flexible electronics offer a multitude of advantages,such as flexibility,lightweight property,portability,and high durability.These unique properties allow for seamless applications to curved and soft surfaces,leading...Flexible electronics offer a multitude of advantages,such as flexibility,lightweight property,portability,and high durability.These unique properties allow for seamless applications to curved and soft surfaces,leading to extensive utilization across a wide range of fields in consumer electronics.These applications,for example,span integrated circuits,solar cells,batteries,wearable devices,bio-implants,soft robotics,and biomimetic applications.Recently,flexible electronic devices have been developed using a variety of materials such as organic,carbon-based,and inorganic semiconducting materials.Silicon(Si)owing to its mature fabrication process,excellent electrical,optical,thermal properties,and cost efficiency,remains a compelling material choice for flexible electronics.Consequently,the research on ultra-thin Si in the context of flexible electronics is studied rigorously nowadays.The thinning of Si is crucially important for flexible electronics as it reduces its bending stiffness and the resultant bending strain,thereby enhancing flexibility while preserving its exceptional properties.This review provides a comprehensive overview of the recent efforts in the fabrication techniques for forming ultra-thin Si using top-down and bottom-up approaches and explores their utilization in flexible electronics and their applications.展开更多
Recognizing handwritten characters remains a critical and formidable challenge within the realm of computervision. Although considerable strides have been made in enhancing English handwritten character recognitionthr...Recognizing handwritten characters remains a critical and formidable challenge within the realm of computervision. Although considerable strides have been made in enhancing English handwritten character recognitionthrough various techniques, deciphering Arabic handwritten characters is particularly intricate. This complexityarises from the diverse array of writing styles among individuals, coupled with the various shapes that a singlecharacter can take when positioned differently within document images, rendering the task more perplexing. Inthis study, a novel segmentation method for Arabic handwritten scripts is suggested. This work aims to locatethe local minima of the vertical and diagonal word image densities to precisely identify the segmentation pointsbetween the cursive letters. The proposed method starts with pre-processing the word image without affectingits main features, then calculates the directions pixel density of the word image by scanning it vertically and fromangles 30° to 90° to count the pixel density fromall directions and address the problem of overlapping letters, whichis a commonly attitude in writing Arabic texts by many people. Local minima and thresholds are also determinedto identify the ideal segmentation area. The proposed technique is tested on samples obtained fromtwo datasets: Aself-curated image dataset and the IFN/ENIT dataset. The results demonstrate that the proposed method achievesa significant improvement in the proportions of cursive segmentation of 92.96% on our dataset, as well as 89.37%on the IFN/ENIT dataset.展开更多
Reliable long-term settlement prediction of a high embankment relates to mountain infrastructure safety.This study developed a novel hybrid model(NHM)that combines a joint denoising technique with an enhanced gray wol...Reliable long-term settlement prediction of a high embankment relates to mountain infrastructure safety.This study developed a novel hybrid model(NHM)that combines a joint denoising technique with an enhanced gray wolf optimizer(EGWO)-n-support vector regression(n-SVR)method.High-embankment field measurements were preprocessed using the joint denoising technique,which in-cludes complete ensemble empirical mode decomposition,singular value decomposition,and wavelet packet transform.Furthermore,high-embankment settlements were predicted using the EGWO-n-SVR method.In this method,the standard gray wolf optimizer(GWO)was improved to obtain the EGWO to better tune the n-SVR model hyperparameters.The proposed NHM was then tested in two case studies.Finally,the influences of the data division ratio and kernel function on the EGWO-n-SVR forecasting performance and prediction efficiency were investigated.The results indicate that the NHM suppresses noise and restores details in high-embankment field measurements.Simultaneously,the NHM out-performs other alternative prediction methods in prediction accuracy and robustness.This demonstrates that the proposed NHM is effective in predicting high-embankment settlements with noisy field mea-surements.Moreover,the appropriate data division ratio and kernel function for EGWO-n-SVR are 7:3 and radial basis function,respectively.展开更多
Dear Editor,In this letter,a novel data-driven adaptive predictive control method is proposed using the triangular dynamic linearization technique.The proposed method only contains one time-varying parameter with expl...Dear Editor,In this letter,a novel data-driven adaptive predictive control method is proposed using the triangular dynamic linearization technique.The proposed method only contains one time-varying parameter with explicit physical meaning,which can prevent severe deviation in parameter estimation.Specifically,a triangular dynamic linearization(TDL)data model is employed to predict future system outputs,and then to correct inaccurate predictive outputs,a feedback regulator is designed.An autotuned weighing factor is introduced to alleviate the computational burden in practical applications and further improve output tracking performance.Closed-loop stability conditions are derived by rigorous analysis.Simulation results are provided to demonstrate the efficacy of the proposed method.展开更多
Epilepsy can be defined as a dysfunction of the brain network,and each type of epilepsy involves different brain-network changes that are implicated diffe rently in the control and propagation of interictal or ictal d...Epilepsy can be defined as a dysfunction of the brain network,and each type of epilepsy involves different brain-network changes that are implicated diffe rently in the control and propagation of interictal or ictal discharges.Gaining more detailed information on brain network alterations can help us to further understand the mechanisms of epilepsy and pave the way for brain network-based precise therapeutic approaches in clinical practice.An increasing number of advanced neuroimaging techniques and electrophysiological techniques such as diffusion tensor imaging-based fiber tra ctography,diffusion kurtosis imaging-based fiber tractography,fiber ball imagingbased tra ctography,electroencephalography,functional magnetic resonance imaging,magnetoencephalography,positron emission tomography,molecular imaging,and functional ultrasound imaging have been extensively used to delineate epileptic networks.In this review,we summarize the relevant neuroimaging and neuroelectrophysiological techniques for assessing structural and functional brain networks in patients with epilepsy,and extensively analyze the imaging mechanisms,advantages,limitations,and clinical application ranges of each technique.A greater focus on emerging advanced technologies,new data analysis software,a combination of multiple techniques,and the construction of personalized virtual epilepsy models can provide a theoretical basis to better understand the brain network mechanisms of epilepsy and make surgical decisions.展开更多
基金the National Science and Technology Supporting Program in the Eleventh Five-Year Plan of China(2006BAC01A11)the Natural Science Founda-tion of Yunnan Province (2006D0092M)
文摘This paper concluded the vegetation restoration technique system in the arid-hot valleys and studied the anti-erosion function, environmental function and biological diversity effects of vegetation restoration on the ecosystem in the arid-hot valleys. The results showed that the soil erodibility decreased significantly after the vegetation restoration. The climate environment of the small watershed had a great improvement after the vegetation restoration, of which the temperature decreased, the humidity increased, the harsh environment of dry and hot in this region changed. The studies of the ecosystem biodiversity were mainly on the analysis of the relations between biodiversity and ecological function of the artificial ecological forest pattern and the natural enclosed treatment mode on the severely of degraded land. It could conclude that the natural enclosed treatment mode is helpful to the biodiversity of the ecosystem and the improvement and stability of the ecosystem, and Leucaena artificial forest restoration pattern reduced the species diversity but optimized the ecological function. Therefore, as to the severely and extremely severely degraded ecosystem in the arid-hot valleys, Leucaena pattern of gully control and natural enclosed treatment mode are the relatively optimal choices.
基金Supported by the Key Research&Development Program of Shaanxi Province of China,No.2024SF-YBXM-447Institutional Foundation of The First Affiliated Hospital of Xi’an Jiaotong University,No.2022MS-07+1 种基金Fundamental Research Funds for the Central Universities,No.xzy022023068Natural Science Foundation of Shaanxi Province,No.2023-JC-QN-0814.
文摘BACKGROUND The magnetic compression technique has been used to establish an animal model of tracheoesophageal fistula(TEF),but the commonly shaped magnets present limitations of poor homogeneity of TEF and poor model control.We designed a Tshaped magnet system to overcome these problems and verified its effectiveness via animal experiments.AIM To investigate the effectiveness of a T-shaped magnet system for establishing a TEF model in beagle dogs.METHODS Twelve beagles were randomly assigned to groups in which magnets of the Tshaped scheme(study group,n=6)or normal magnets(control group,n=6)were implanted into the trachea and esophagus separately under gastroscopy.Operation time,operation success rate,and accidental injury were recorded.After operation,the presence and timing of cough and the time of magnet shedding were observed.Dogs in the control group were euthanized after X-ray and gastroscopy to confirm establishment of TEFs after coughing,and gross specimens of TEFs were obtained.Dogs in the study group were euthanized after X-ray and gastroscopy 2 wk after surgery,and gross specimens were obtained.Fistula size was measured in all animals,and then harvested fistula specimens were examined by hematoxylin and eosin(HE)and Masson trichrome staining.RESULTS The operation success rate was 100%for both groups.Operation time did not differ between the study group(5.25 min±1.29 min)and the control group(4.75 min±1.70 min;P=0.331).No bleeding,perforation,or unplanned magnet attraction occurred in any animal during the operation.In the early postoperative period,all dogs ate freely and were generally in good condition.Dogs in the control group had severe cough after drinking water at 6-9 d after surgery.X-ray indicated that the magnets had entered the stomach,and gastroscopy showed TEF formation.Gross specimens of TEFs from the control group showed the formation of fistulas with a diameter of 4.94 mm±1.29 mm(range,3.52-6.56 mm).HE and Masson trichrome staining showed scar tissue formation and hierarchical structural disorder at the fistulas.Dogs in the study group did not exhibit obvious coughing after surgery.X-ray examination 2 wk after surgery indicated fixed magnet positioning,and gastroscopy showed no change in magnet positioning.The magnets were removed using a snare under endoscopy,and TEF was observed.Gross specimens showed well-formed fistulas with a diameter of 6.11 mm±0.16 mm(range,5.92-6.36 mm),which exceeded that in the control group(P<0.001).Scar formation was observed on the internal surface of fistulas by HE and Masson trichrome staining,and the structure was more regular than that in the control group.CONCLUSION Use of the modified T-shaped magnet scheme is safe and feasible for establishing TEF and can achieve a more stable and uniform fistula size compared with ordinary magnets.Most importantly,this model offers better controllability,which improves the flexibility of follow-up studies.
文摘Forecasting travel demand requires a grasp of individual decision-making behavior.However,transport mode choice(TMC)is determined by personal and contextual factors that vary from person to person.Numerous characteristics have a substantial impact on travel behavior(TB),which makes it important to take into account while studying transport options.Traditional statistical techniques frequently presume linear correlations,but real-world data rarely follows these presumptions,which may make it harder to grasp the complex interactions.Thorough systematic review was conducted to examine how machine learning(ML)approaches might successfully capture nonlinear correlations that conventional methods may ignore to overcome such challenges.An in-depth analysis of discrete choice models(DCM)and several ML algorithms,datasets,model validation strategies,and tuning techniques employed in previous research is carried out in the present study.Besides,the current review also summarizes DCM and ML models to predict TMC and recognize the determinants of TB in an urban area for different transport modes.The two primary goals of our study are to establish the present conceptual frameworks for the factors influencing the TMC for daily activities and to pinpoint methodological issues and limitations in previous research.With a total of 39 studies,our findings shed important light on the significance of considering factors that influence the TMC.The adjusted kernel algorithms and hyperparameter-optimized ML algorithms outperform the typical ML algorithms.RF(random forest),SVM(support vector machine),ANN(artificial neural network),and interpretable ML algorithms are the most widely used ML algorithms for the prediction of TMC where RF achieved an R2 of 0.95 and SVM achieved an accuracy of 93.18%;however,the adjusted kernel enhanced the accuracy of SVM 99.81%which shows that the interpretable algorithms outperformed the typical algorithms.The sensitivity analysis indicates that the most significant parameters influencing TMC are the age,total trip time,and the number of drivers.
文摘The rapid evolution of wireless communication technologies has underscored the critical role of antennas in ensuring seamless connectivity.Antenna defects,ranging from manufacturing imperfections to environmental wear,pose significant challenges to the reliability and performance of communication systems.This review paper navigates the landscape of antenna defect detection,emphasizing the need for a nuanced understanding of various defect types and the associated challenges in visual detection.This review paper serves as a valuable resource for researchers,engineers,and practitioners engaged in the design and maintenance of communication systems.The insights presented here pave the way for enhanced reliability in antenna systems through targeted defect detection measures.In this study,a comprehensive literature analysis on computer vision algorithms that are employed in end-of-line visual inspection of antenna parts is presented.The PRISMA principles will be followed throughout the review,and its goals are to provide a summary of recent research,identify relevant computer vision techniques,and evaluate how effective these techniques are in discovering defects during inspections.It contains articles from scholarly journals as well as papers presented at conferences up until June 2023.This research utilized search phrases that were relevant,and papers were chosen based on whether or not they met certain inclusion and exclusion criteria.In this study,several different computer vision approaches,such as feature extraction and defect classification,are broken down and analyzed.Additionally,their applicability and performance are discussed.The review highlights the significance of utilizing a wide variety of datasets and measurement criteria.The findings of this study add to the existing body of knowledge and point researchers in the direction of promising new areas of investigation,such as real-time inspection systems and multispectral imaging.This review,on its whole,offers a complete study of computer vision approaches for quality control in antenna parts.It does so by providing helpful insights and drawing attention to areas that require additional exploration.
基金Supported by Discipline Advancement Program of Shanghai Fourth People’s Hospital,No.SY-XKZT-2020-2013.
文摘BACKGROUND Postoperative delirium,particularly prevalent in elderly patients after abdominal cancer surgery,presents significant challenges in clinical management.AIM To develop a synthetic minority oversampling technique(SMOTE)-based model for predicting postoperative delirium in elderly abdominal cancer patients.METHODS In this retrospective cohort study,we analyzed data from 611 elderly patients who underwent abdominal malignant tumor surgery at our hospital between September 2020 and October 2022.The incidence of postoperative delirium was recorded for 7 d post-surgery.Patients were divided into delirium and non-delirium groups based on the occurrence of postoperative delirium or not.A multivariate logistic regression model was used to identify risk factors and develop a predictive model for postoperative delirium.The SMOTE technique was applied to enhance the model by oversampling the delirium cases.The model’s predictive accuracy was then validated.RESULTS In our study involving 611 elderly patients with abdominal malignant tumors,multivariate logistic regression analysis identified significant risk factors for postoperative delirium.These included the Charlson comorbidity index,American Society of Anesthesiologists classification,history of cerebrovascular disease,surgical duration,perioperative blood transfusion,and postoperative pain score.The incidence rate of postoperative delirium in our study was 22.91%.The original predictive model(P1)exhibited an area under the receiver operating characteristic curve of 0.862.In comparison,the SMOTE-based logistic early warning model(P2),which utilized the SMOTE oversampling algorithm,showed a slightly lower but comparable area under the curve of 0.856,suggesting no significant difference in performance between the two predictive approaches.CONCLUSION This study confirms that the SMOTE-enhanced predictive model for postoperative delirium in elderly abdominal tumor patients shows performance equivalent to that of traditional methods,effectively addressing data imbalance.
基金supported by the U.S.National Science Foundation (2208972,2120559,and 2323117)
文摘Rechargeable battery cycling performance and related safety have been persistent concerns.It is crucial to decipher the capacity fading induced by electrode material failure via a range of techniques.Among these,synchrotron-based X-ray techniques with high flux and brightness play a key role in understanding degradation mechanisms.In this comprehensive review,we summarize recent advancements in degra-dation modes and mechanisms that were revealed by synchrotron X-ray methodologies.Subsequently,an overview of X-ray absorption spectroscopy and X-ray scattering techniques is introduced for charac-terizing failure phenomena at local coordination atomic environment and long-range order crystal struc-ture scale,respectively.At last,we envision the future of exploring material failure mechanism.
基金[King Abdulaziz University][Deanship of Scientific Research]Grant Number[KEP-PHD-20-611-42].
文摘Recently,researchers have shown increasing interest in combining more than one programming model into systems running on high performance computing systems(HPCs)to achieve exascale by applying parallelism at multiple levels.Combining different programming paradigms,such as Message Passing Interface(MPI),Open Multiple Processing(OpenMP),and Open Accelerators(OpenACC),can increase computation speed and improve performance.During the integration of multiple models,the probability of runtime errors increases,making their detection difficult,especially in the absence of testing techniques that can detect these errors.Numerous studies have been conducted to identify these errors,but no technique exists for detecting errors in three-level programming models.Despite the increasing research that integrates the three programming models,MPI,OpenMP,and OpenACC,a testing technology to detect runtime errors,such as deadlocks and race conditions,which can arise from this integration has not been developed.Therefore,this paper begins with a definition and explanation of runtime errors that result fromintegrating the three programming models that compilers cannot detect.For the first time,this paper presents a classification of operational errors that can result from the integration of the three models.This paper also proposes a parallel hybrid testing technique for detecting runtime errors in systems built in the C++programming language that uses the triple programming models MPI,OpenMP,and OpenACC.This hybrid technology combines static technology and dynamic technology,given that some errors can be detected using static techniques,whereas others can be detected using dynamic technology.The hybrid technique can detect more errors because it combines two distinct technologies.The proposed static technology detects a wide range of error types in less time,whereas a portion of the potential errors that may or may not occur depending on the 4502 CMC,2023,vol.74,no.2 operating environment are left to the dynamic technology,which completes the validation.
基金supported by the Spanish“Plan Nacional de Investigación Científica,Desarrollo e Innovación Tecnológica,Ministerio de Economía y Competitividad(Instituto de Salud CarlosⅢ)”,Grant FIS PI20-0318 co-financed by“Fondo Europeo de Desarrollo Regional ERDF-FEDER European Union”Grant P18-RT-5059“Plan Andaluz de Investigación,Desarrollo e Innovación(PAIDI 2020),Consejería de Transformación Económica,Industria,Conocimiento y Universidades,Junta de Andalucía,Espana”(all to VC)Grant PPJIA202219“Ayudas del plan propio UGR 2022,Plan propio de investigación y transferencia,Universidad de Granada,Espana”(to JCA andóDGG)。
文摘The myelin sheath is a lipoprotein-rich,multilayered structure capable of increasing conduction velocity in central and peripheral myelinated nerve fibers.Due to the complex structure and composition of myelin,various histological techniques have been developed over the centuries to evaluate myelin under normal,pathological or experimental conditions.Today,methods to assess myelin integrity or content are key tools in both clinical diagnosis and neuroscience research.In this review,we provide an updated summary of the composition and structure of the myelin sheath and discuss some histological procedures,from tissue fixation and processing techniques to the most used and practical myelin histological staining methods.Considering the lipoprotein nature of myelin,the main features and technical details of the different available methods that can be used to evaluate the lipid or protein components of myelin are described,as well as the precise ultrastructural techniques.
文摘The development of intestinal anastomosis techniques,including hand suturing,stapling,and compression anastomoses,has been a significant advancement in surgical practice.These methods aim to prevent leakage and minimize tissue fibrosis,which can lead to stricture formation.The healing process involves various phases:hemostasis and inflammation,proliferation,and remodeling.Mechanical staplers and sutures can cause inflammation and fibrosis due to the release of profibrotic chemokines.Compression anastomosis devices,including those made of nickel-titanium alloy,offer a minimally invasive option for various surgical challenges and have shown safety and efficacy.However,despite advancements,anastomotic techniques are evaluated based on leakage risk,with complications being a primary concern.Newer devices like Magnamosis use magnetic rings for compression anastomosis,demonstrating greater strength and patency compared to stapling.Magnetic technology is also being explored for other medical treatments.While there are promising results,particularly in animal models,the realworld application in humans is limited,and further research is needed to assess their safety and practicality.
文摘While emerging technologies such as the Internet of Things(IoT)have many benefits,they also pose considerable security challenges that require innovative solutions,including those based on artificial intelligence(AI),given that these techniques are increasingly being used by malicious actors to compromise IoT systems.Although an ample body of research focusing on conventional AI methods exists,there is a paucity of studies related to advanced statistical and optimization approaches aimed at enhancing security measures.To contribute to this nascent research stream,a novel AI-driven security system denoted as“AI2AI”is presented in this work.AI2AI employs AI techniques to enhance the performance and optimize security mechanisms within the IoT framework.We also introduce the Genetic Algorithm Anomaly Detection and Prevention Deep Neural Networks(GAADPSDNN)sys-tem that can be implemented to effectively identify,detect,and prevent cyberattacks targeting IoT devices.Notably,this system demonstrates adaptability to both federated and centralized learning environments,accommodating a wide array of IoT devices.Our evaluation of the GAADPSDNN system using the recently complied WUSTL-IIoT and Edge-IIoT datasets underscores its efficacy.Achieving an impressive overall accuracy of 98.18%on the Edge-IIoT dataset,the GAADPSDNN outperforms the standard deep neural network(DNN)classifier with 94.11%accuracy.Furthermore,with the proposed enhancements,the accuracy of the unoptimized random forest classifier(80.89%)is improved to 93.51%,while the overall accuracy(98.18%)surpasses the results(93.91%,94.67%,94.94%,and 94.96%)achieved when alternative systems based on diverse optimization techniques and the same dataset are employed.The proposed optimization techniques increase the effectiveness of the anomaly detection system by efficiently achieving high accuracy and reducing the computational load on IoT devices through the adaptive selection of active features.
基金supported by the Deanship of Scientific Research at the University of Tabuk through Research No.S-1443-0111.
文摘Introducing IoT devices to healthcare fields has made it possible to remotely monitor patients’information and provide a proper diagnosis as needed,resulting in the Internet of Medical Things(IoMT).However,obtaining good security features that ensure the integrity and confidentiality of patient’s information is a significant challenge.However,due to the computational resources being limited,an edge device may struggle to handle heavy detection tasks such as complex machine learning algorithms.Therefore,designing and developing a lightweight detection mechanism is crucial.To address the aforementioned challenges,a new lightweight IDS approach is developed to effectively combat a diverse range of cyberattacks in IoMT networks.The proposed anomaly-based IDS is divided into three steps:pre-processing,feature selection,and decision.In the pre-processing phase,data cleaning and normalization are performed.In the feature selection step,the proposed approach uses two data-driven kernel techniques:kernel principal component analysis and kernel partial least square techniques to reduce the dimension of extracted features and to ameliorate the detection results.Therefore,in decision step,in order to classify whether the traffic flow is normal or malicious the kernel extreme learning machine is used.To check the efficiency of the developed detection scheme,a modern IoMT dataset named WUSTL-EHMS-2020 is considered to evaluate and discuss the achieved results.The proposed method achieved 99.9%accuracy,99.8%specificity,100%Sensitivity,99.9 F-score.
文摘The increasing number of security holes in the Internet of Things(IoT)networks creates a question about the reliability of existing network intrusion detection systems.This problem has led to the developing of a research area focused on improving network-based intrusion detection system(NIDS)technologies.According to the analysis of different businesses,most researchers focus on improving the classification results of NIDS datasets by combining machine learning and feature reduction techniques.However,these techniques are not suitable for every type of network.In light of this,whether the optimal algorithm and feature reduction techniques can be generalized across various datasets for IoT networks remains.The paper aims to analyze the methods used in this research and whether they can be generalized to other datasets.Six ML models were used in this study,namely,logistic regression(LR),decision trees(DT),Naive Bayes(NB),random forest(RF),K-nearest neighbors(KNN),and linear SVM.The primary detection algorithms used in this study,Principal Component(PCA)and Gini Impurity-Based Weighted Forest(GIWRF)evaluated against three global ToN-IoT datasets,UNSW-NB15,and Bot-IoT datasets.The optimal number of dimensions for each dataset was not studied by applying the PCA algorithm.It is stated in the paper that the selection of datasets affects the performance of the FE techniques and detection algorithms used.Increasing the efficiency of this research area requires a comprehensive standard feature set that can be used to improve quality over time.
文摘In this era of post-COVID-19,humans are psychologically restricted to interact less with other humans.According to the world health organization(WHO),there are many scenarios where human interactions cause severe multiplication of viruses from human to human and spread worldwide.Most healthcare systems shifted to isolation during the pandemic and a very restricted work environment.Investigations were done to overcome the remedy,and the researcher developed different techniques and recommended solutions.Telepresence robot was the solution achieved by all industries to continue their operations but with almost zero physical interaction with other humans.It played a vital role in this perspective to help humans to perform daily routine tasks.Healthcare workers can use telepresence robots to interact with patients who visit the healthcare center for initial diagnosis for better healthcare system performance without direct interaction.The presented paper aims to compare different telepresence robots and their different controlling techniques to perform the needful in the respective scenario of healthcare environments.This paper comprehensively analyzes and reviews the applications of presented techniques to control different telepresence robots.However,our feature-wise analysis also points to specific technical,appropriate,and ethical challenges that remain to be solved.The proposed investigation summarizes the need for further multifaceted research on the design and impact of a telepresence robot for healthcare centers,building on new perceptions during the COVID-19 pandemic.
基金supported by the National Natural Science Foundation of China(No.52274252)the Key Science and Technology Project of Changsha City,China(No.kq2102005)+1 种基金the Special Fund for the Construction of Innovative Province in Hunan Province,China(Nos.2020RC3038 and 2022WK4004)the Changsha City Fund for Distinguished and Innovative Young Scholars,China(No.kq1802007).
文摘The combination of electrospinning and hot pressing,namely the electrospinning-hot pressing technique(EHPT),is an efficient and convenient method for preparing nanofibrous composite materials with good energy storage performance.The emerging composite membrane prepared by EHPT,which exhibits the advantages of large surface area,controllable morphology,and compact structure,has attracted immense attention.In this paper,the conduction mechanism of composite membranes in thermal and electrical energy storage and the performance enhancement method based on the fabrication process of EHPT are systematically discussed.Moreover,the state-of-the-art applications of composite membranes in these two fields are introduced.In particular,in the field of thermal energy storage,EHPT-prepared membranes have longitudinal and transverse nanofibers,which generate unique thermal conductivity pathways;also,these nanofibers offer enough space for the filling of functional materials.Moreover,EHPT-prepared membranes are beneficial in thermal management systems,building energy conservation,and electrical energy storage,e.g.,improving the electrochemical properties of the separators as well as their mechanical and thermal stability.The application of electrospinning-hot pressing membranes on capacitors,lithium-ion batteries(LIBs),fuel cells,sodium-ion batteries(SIBs),and hydrogen bromine flow batteries(HBFBs)still requires examination.In the future,EHPT is expected to make the field more exciting through its own technological breakthroughs or be combined with other technologies to produce intelligent materials.
基金supported by the Natural Science Foundation of Liaoning Province,China(Grant No.:2023-MS-172).
文摘Tyrosine kinase inhibitors(TKIs)have emerged as the first-line small molecule drugs in many cancer therapies,exerting their effects by impeding aberrant cell growth and proliferation through the modulation of tyrosine kinase-mediated signaling pathways.However,there exists a substantial inter-individual variability in the concentrations of certain TKIs and their metabolites,which may render patients with compromised immune function susceptible to diverse infections despite receiving theoretically efficacious anticancer treatments,alongside other potential side effects or adverse reactions.Therefore,an urgent need exists for an up-to-date review concerning the biological matrices relevant to bioanalysis and the sampling methods,clinical pharmacokinetics,and therapeutic drug monitoring of different TKIs.This paper provides a comprehensive overview of the advancements in pretreatment methods,such as protein precipitation(PPT),liquid-liquid extraction(LLE),solid-phase extraction(SPE),micro-SPE(μ-SPE),magnetic SPE(MSPE),and vortex-assisted dispersive SPE(VA-DSPE)achieved since 2017.It also highlights the latest analysis techniques such as newly developed high performance liquid chromatography(HPLC)and high-resolution mass spectrometry(HRMS)methods,capillary electrophoresis(CE),gas chromatography(GC),supercritical fluid chromatography(SFC)procedures,surface plasmon resonance(SPR)assays as well as novel nanoprobes-based biosensing techniques.In addition,a comparison is made between the advantages and disadvantages of different approaches while presenting critical challenges and prospects in pharmacokinetic studies and therapeutic drug monitoring.
基金supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. RS-2024-00353768)the Yonsei Fellowship, funded by Lee Youn Jae. This study was funded by the KIST Institutional Program Project No. 2E31603-22-140 (K J Y). S M W acknowledges the support by National Research Foundation of Korea (NRF) grant funded by the Korea government (Grant Nos. NRF-2021R1C1C1009410, NRF2022R1A4A3032913 and RS-2024-00411904)
文摘Flexible electronics offer a multitude of advantages,such as flexibility,lightweight property,portability,and high durability.These unique properties allow for seamless applications to curved and soft surfaces,leading to extensive utilization across a wide range of fields in consumer electronics.These applications,for example,span integrated circuits,solar cells,batteries,wearable devices,bio-implants,soft robotics,and biomimetic applications.Recently,flexible electronic devices have been developed using a variety of materials such as organic,carbon-based,and inorganic semiconducting materials.Silicon(Si)owing to its mature fabrication process,excellent electrical,optical,thermal properties,and cost efficiency,remains a compelling material choice for flexible electronics.Consequently,the research on ultra-thin Si in the context of flexible electronics is studied rigorously nowadays.The thinning of Si is crucially important for flexible electronics as it reduces its bending stiffness and the resultant bending strain,thereby enhancing flexibility while preserving its exceptional properties.This review provides a comprehensive overview of the recent efforts in the fabrication techniques for forming ultra-thin Si using top-down and bottom-up approaches and explores their utilization in flexible electronics and their applications.
文摘Recognizing handwritten characters remains a critical and formidable challenge within the realm of computervision. Although considerable strides have been made in enhancing English handwritten character recognitionthrough various techniques, deciphering Arabic handwritten characters is particularly intricate. This complexityarises from the diverse array of writing styles among individuals, coupled with the various shapes that a singlecharacter can take when positioned differently within document images, rendering the task more perplexing. Inthis study, a novel segmentation method for Arabic handwritten scripts is suggested. This work aims to locatethe local minima of the vertical and diagonal word image densities to precisely identify the segmentation pointsbetween the cursive letters. The proposed method starts with pre-processing the word image without affectingits main features, then calculates the directions pixel density of the word image by scanning it vertically and fromangles 30° to 90° to count the pixel density fromall directions and address the problem of overlapping letters, whichis a commonly attitude in writing Arabic texts by many people. Local minima and thresholds are also determinedto identify the ideal segmentation area. The proposed technique is tested on samples obtained fromtwo datasets: Aself-curated image dataset and the IFN/ENIT dataset. The results demonstrate that the proposed method achievesa significant improvement in the proportions of cursive segmentation of 92.96% on our dataset, as well as 89.37%on the IFN/ENIT dataset.
基金We acknowledge the funding support from the National Natural Science Foundation of China(Grant No.51808462)the Natural Science Foundation Project of Sichuan Province,China(Grant No.2023NSFSC0346)the Science and Technology Project of Inner Mongolia Transportation Department,China(Grant No.NJ-2022-14).
文摘Reliable long-term settlement prediction of a high embankment relates to mountain infrastructure safety.This study developed a novel hybrid model(NHM)that combines a joint denoising technique with an enhanced gray wolf optimizer(EGWO)-n-support vector regression(n-SVR)method.High-embankment field measurements were preprocessed using the joint denoising technique,which in-cludes complete ensemble empirical mode decomposition,singular value decomposition,and wavelet packet transform.Furthermore,high-embankment settlements were predicted using the EGWO-n-SVR method.In this method,the standard gray wolf optimizer(GWO)was improved to obtain the EGWO to better tune the n-SVR model hyperparameters.The proposed NHM was then tested in two case studies.Finally,the influences of the data division ratio and kernel function on the EGWO-n-SVR forecasting performance and prediction efficiency were investigated.The results indicate that the NHM suppresses noise and restores details in high-embankment field measurements.Simultaneously,the NHM out-performs other alternative prediction methods in prediction accuracy and robustness.This demonstrates that the proposed NHM is effective in predicting high-embankment settlements with noisy field mea-surements.Moreover,the appropriate data division ratio and kernel function for EGWO-n-SVR are 7:3 and radial basis function,respectively.
基金supported in part by the National Natural Science Foundation of China(62173002,52301408,62173255)the Beijing Natural Science Foundation(4222045).
文摘Dear Editor,In this letter,a novel data-driven adaptive predictive control method is proposed using the triangular dynamic linearization technique.The proposed method only contains one time-varying parameter with explicit physical meaning,which can prevent severe deviation in parameter estimation.Specifically,a triangular dynamic linearization(TDL)data model is employed to predict future system outputs,and then to correct inaccurate predictive outputs,a feedback regulator is designed.An autotuned weighing factor is introduced to alleviate the computational burden in practical applications and further improve output tracking performance.Closed-loop stability conditions are derived by rigorous analysis.Simulation results are provided to demonstrate the efficacy of the proposed method.
基金supported by the Natural Science Foundation of Sichuan Province of China,Nos.2022NSFSC1545 (to YG),2022NSFSC1387 (to ZF)the Natural Science Foundation of Chongqing of China,Nos.CSTB2022NSCQ-LZX0038,cstc2021ycjh-bgzxm0035 (both to XT)+3 种基金the National Natural Science Foundation of China,No.82001378 (to XT)the Joint Project of Chongqing Health Commission and Science and Technology Bureau,No.2023QNXM009 (to XT)the Science and Technology Research Program of Chongqing Education Commission of China,No.KJQN202200435 (to XT)the Chongqing Talents:Exceptional Young Talents Project,No.CQYC202005014 (to XT)。
文摘Epilepsy can be defined as a dysfunction of the brain network,and each type of epilepsy involves different brain-network changes that are implicated diffe rently in the control and propagation of interictal or ictal discharges.Gaining more detailed information on brain network alterations can help us to further understand the mechanisms of epilepsy and pave the way for brain network-based precise therapeutic approaches in clinical practice.An increasing number of advanced neuroimaging techniques and electrophysiological techniques such as diffusion tensor imaging-based fiber tra ctography,diffusion kurtosis imaging-based fiber tractography,fiber ball imagingbased tra ctography,electroencephalography,functional magnetic resonance imaging,magnetoencephalography,positron emission tomography,molecular imaging,and functional ultrasound imaging have been extensively used to delineate epileptic networks.In this review,we summarize the relevant neuroimaging and neuroelectrophysiological techniques for assessing structural and functional brain networks in patients with epilepsy,and extensively analyze the imaging mechanisms,advantages,limitations,and clinical application ranges of each technique.A greater focus on emerging advanced technologies,new data analysis software,a combination of multiple techniques,and the construction of personalized virtual epilepsy models can provide a theoretical basis to better understand the brain network mechanisms of epilepsy and make surgical decisions.