Mainstream media play a crucial role in constructing the cultural memory of a city.This study used 319 short videos released by“Hi Chengdu,”a new media product of Chengdu Radio and Television,as samples.Based on the...Mainstream media play a crucial role in constructing the cultural memory of a city.This study used 319 short videos released by“Hi Chengdu,”a new media product of Chengdu Radio and Television,as samples.Based on the grounded theory,a research framework encompassing“content,technology,and discourse”was established to explore the paths through which mainstream media construct the cultural memory.Regarding content,this paper emphasized temporal and spatial contexts and urban spaces,delving deep into the themes of the cultural memory and vehicles for it.In terms of technology,this paper discussed the practice of leveraging audio/visual-mode discourse to stitch together the impressions of a city and evoke emotional resonance to create a“flow”of memory.As for discourse,this paper looked at the performance of a communication ritual to frame concepts and shape urban identity.It is essential to break free from conventional thinking and leverage local culture as the primary driving force to further boost a city’s productivity,in order to excel in cultural communication.展开更多
Sleep quality in young adults is compromised. Instead of the recommended 7 hours, young adults’ schedule interruptions disturb sleep to a typical six and a half hours, with common disturbances in falling asleep and s...Sleep quality in young adults is compromised. Instead of the recommended 7 hours, young adults’ schedule interruptions disturb sleep to a typical six and a half hours, with common disturbances in falling asleep and staying asleep. Recent literature has identified an association between academic performance, negative mood state and low activity level in young adults with sleep disturbances. Young adulthood is a time for the installation of sleep health. Both individual and schedule impositions to the young adults’ sleep schedule are to be modified to obtain Sleep Health. Recent research has identified daytime light effects on sleep such as blue light from electronics as alerting and low level light for relaxation. The aim of this study was to identify sleep quality effects with varying light exposures. It was hypothesized that bright (>450 lux) light conditions would be considered focusing and low light (<220 lux) would be considered calming. We hypothesized that sleep quality would improve by 5% with the introduction of a calm light condition. Undergraduates from a small midwestern university were invited to participate in the study in exchange for a gift card. Six participants completed the study, two males, four females all between 21 - 24 years old. Both hypotheses were supported by qualitative analysis.展开更多
The rapid development of intelligent technology has led to its introduction into the field of electrical lighting in buildings.It provides more technical support for system design,use,and management,and creates a comf...The rapid development of intelligent technology has led to its introduction into the field of electrical lighting in buildings.It provides more technical support for system design,use,and management,and creates a comfortable and safe living environment.The adoption of intelligent technology enables the creation of an intelligent management system,where controllers and sensors are used to adjust the light source within the building,monitor and manage the lighting system in real time,monitor the energy consumption and safety of the system,and achieve the goal of energy saving and emission reduction.This paper briefly discusses the application and significance of intelligent technology in electrical lighting and puts forward design ideas to optimize electrical lighting and measures for lighting system management.展开更多
Taking the National Experimental Teaching Demonstration Center of the Central Academy of Drama as an example,this article explores the construction and development of the National Experimental Teaching Demonstration C...Taking the National Experimental Teaching Demonstration Center of the Central Academy of Drama as an example,this article explores the construction and development of the National Experimental Teaching Demonstration Center for the practical teaching of drama and film and television disciplines.The article first introduces the background and importance of the demonstration center and then analyzes in depth the construction content and achievements of the demonstration center from four aspects:practical teaching philosophy,practical teaching system,practical teaching resources,and practical teaching effects.Finally,the article summarizes the experience and shortcomings of the demonstration center and proposes future development directions and suggestions.展开更多
With the rapid development of electronic information technology,the Internet of Things(IoT),Internet technology,and modern communication technology,people are demanding higher standards for the building environment.Es...With the rapid development of electronic information technology,the Internet of Things(IoT),Internet technology,and modern communication technology,people are demanding higher standards for the building environment.Especially in modern large-scale buildings with high levels of industrialization,lighting systems should also be optimized accordingly.This article explores the application path of intelligent lighting in thermal power plants for reference.展开更多
The construction and installation of street lighting is an important element in the modernization of China’s cities.Besides,it also plays an important role in raising the living standards of the people.In recent year...The construction and installation of street lighting is an important element in the modernization of China’s cities.Besides,it also plays an important role in raising the living standards of the people.In recent years,with the technological and economic development,smart street lighting has gradually emerged.Key functions of smart street lighting include road illumination,cultural promotion,meteorological monitoring,public broadcasting,and 5G micro-base stations.The overall quality of smart street lighting construction directly impacts the effectiveness of urban development and the city’s comprehensive growth.This paper analyzes the concept of smart street lighting,its advantages and disadvantages,the functionalities of smart street light systems,and the application of smart street lighting in urban road illumination.展开更多
Currently,to effectively construct high-quality smart cities and achieve comprehensive governance goals,various industries must embrace the transformation and upgrading of traditional management methods through the in...Currently,to effectively construct high-quality smart cities and achieve comprehensive governance goals,various industries must embrace the transformation and upgrading of traditional management methods through the integration of new technologies.Among these,landscape smart lighting serves as a crucial tool for advancing smart city development.By judiciously applying this technology,it is possible to enhance traditional lighting methods and offer people novel experiences in their daily lives.Recognizing this importance,this article analyzes and organizes the content of landscape smart lighting,delves into its system characteristics,and summarizes its principles and practices in the field of architectural engineering as practical references for application scenarios.展开更多
In the context of promoting green energy transition and addressing climate change globally,solar energy,as a clean and renewable energy source,has gradually become a hot topic for research.Solar streetlight systems re...In the context of promoting green energy transition and addressing climate change globally,solar energy,as a clean and renewable energy source,has gradually become a hot topic for research.Solar streetlight systems realize energy self-sufficiency and environment-friendly lighting by integrating photovoltaic power generation technology and efficient LED lighting technology.By comprehensively analyzing the current status of the application of solar streetlights at home and abroad,this paper discusses its technical advantages,market penetration,and challenges in its development.In terms of technical characteristics,this paper focuses on analyzing the key technologies such as energy conversion efficiency and intelligent control systems of solar streetlights.展开更多
The article mainly studies the application strategy of automatic addressable single-lamp control technology in tunnel lighting.It encompasses an introduction to this technology,an analysis of the tunnel lighting syste...The article mainly studies the application strategy of automatic addressable single-lamp control technology in tunnel lighting.It encompasses an introduction to this technology,an analysis of the tunnel lighting system using automatic addressable single-lamp control technology,and outlines the main development direction for this technology in modern tunnel lighting.The aim is to offer insights that can inform the rational deployment of this technology,thereby enhancing the lighting control effectiveness in modern tunnels and meeting their specific lighting requirements more effectively.展开更多
LED lights have been widely used in urban night space lighting in recent years as they are small,energy-saving,and efficient.This article explores the use of LEDs in bridge night space lighting and their application s...LED lights have been widely used in urban night space lighting in recent years as they are small,energy-saving,and efficient.This article explores the use of LEDs in bridge night space lighting and their application strategies.The aim is to offer valuable insights and references for urban planners and bridge lighting designers in China.By advancing the application of LED technology in bridge night lighting,the goal is to enhance the city’s nighttime ambiance,making the bridge an iconic landmark and a defining feature of the city.展开更多
A television based multistatic radar system is described. The commercial television transmitter is used as the illuminator in the multistatic radar system. The reflected commercial television signals are measured by ...A television based multistatic radar system is described. The commercial television transmitter is used as the illuminator in the multistatic radar system. The reflected commercial television signals are measured by an array of sensors. A data processing scheme is developed that adapts to the poor signal processing ability. The innovation is focused on the construction of the observation space, which could reduce the non linearity error. The new method leads to better system stability than the traditional one. Monte Carlo simulation is utilized and compared with the traditional method.展开更多
Amyotrophic lateral sclerosis is a devastating neurodegenerative disease for which the current treatment approaches remain severely limited.The principal pathological alterations of the disease include the selective d...Amyotrophic lateral sclerosis is a devastating neurodegenerative disease for which the current treatment approaches remain severely limited.The principal pathological alterations of the disease include the selective degeneration of motor neurons in the brain,brainstem,and spinal cord,as well as abnormal protein deposition in the cytoplasm of neurons and glial cells.The biological markers under extensive scrutiny are predominantly located in the cerebrospinal fluid,blood,and even urine.Among these biomarke rs,neurofilament proteins and glial fibrillary acidic protein most accurately reflect the pathologic changes in the central nervous system,while creatinine and creatine kinase mainly indicate pathological alterations in the peripheral nerves and muscles.Neurofilament light chain levels serve as an indicator of neuronal axonal injury that remain stable throughout disease progression and are a promising diagnostic and prognostic biomarker with high specificity and sensitivity.However,there are challenges in using neurofilament light chain to diffe rentiate amyotrophic lateral sclerosis from other central nervous system diseases with axonal injury.Glial fibrillary acidic protein predominantly reflects the degree of neuronal demyelination and is linked to non-motor symptoms of amyotrophic lateral sclerosis such as cognitive impairment,oxygen saturation,and the glomerular filtration rate.TAR DNA-binding protein 43,a pathological protein associated with amyotrophic lateral sclerosis,is emerging as a promising biomarker,particularly with advancements in exosome-related research.Evidence is currently lacking for the value of creatinine and creatine kinase as diagnostic markers;however,they show potential in predicting disease prognosis.Despite the vigorous progress made in the identification of amyotrophic lateral sclerosis biomarkers in recent years,the quest for definitive diagnostic and prognostic biomarke rs remains a formidable challenge.This review summarizes the latest research achievements concerning blood biomarkers in amyotrophic lateral sclerosis that can provide a more direct basis for the differential diagnosis and prognostic assessment of the disease beyond a reliance on clinical manifestations and electromyography findings.展开更多
Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative diseases.However,little is k...Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative diseases.However,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°C.We aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large cohort.Plasma samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline project.These samples were stored at-80°C for up to 6 years before being used in this study.Our results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage time.However,the level of total tau showed a negative correlation with sample storage time.Notably,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage time.This was not observed in individuals with cognitive impairment.Consequently,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage time.Therefore,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's disease.Furthermore,in cohort studies,it is important to consider the impact of storage time on the overall results.展开更多
The cGAS–STING pathway plays an important role in ischemia-reperfusion injury in the heart,liver,brain,and kidney,but its role and mechanisms in cerebral ischemia-reperfusion injury have not been systematically revie...The cGAS–STING pathway plays an important role in ischemia-reperfusion injury in the heart,liver,brain,and kidney,but its role and mechanisms in cerebral ischemia-reperfusion injury have not been systematically reviewed.Here,we outline the components of the cGAS–STING pathway and then analyze its role in autophagy,ferroptosis,cellular pyroptosis,disequilibrium of calcium homeostasis,inflammatory responses,disruption of the blood–brain barrier,microglia transformation,and complement system activation following cerebral ischemia-reperfusion injury.We further analyze the value of cGAS–STING pathway inhibitors in the treatment of cerebral ischemia-reperfusion injury and conclude that the pathway can regulate cerebral ischemia-reperfusion injury through multiple mechanisms.Inhibition of the cGAS–STING pathway may be helpful in the treatment of cerebral ischemia-reperfusion injury.展开更多
Far-red(FR) light regulates phytochrome-mediated morphological and physiological plant responses.This study aims to investigate how greenhouse tomato morphology and production response to different durations of FR lig...Far-red(FR) light regulates phytochrome-mediated morphological and physiological plant responses.This study aims to investigate how greenhouse tomato morphology and production response to different durations of FR light during daytime and at the end of day(EOD).High-wire tomato plants were grown under intra-canopy lighting consisting of red(peak wavelength at 640 nm) and blue(peak wavelength at 450 nm) light-emitting diodes(LEDs) with photosynthetic photon flux density(PPFD) of 144 μmol m–2 s–1 at 10 cm away from the lamps,and combined with overhead supplemental FR light(peak wavelength at 735 nm) with PPFD of 43 μmol m–2 s–1 at 20 cm below the lamps.Plants were exposed to three durations of FR supplemental lighting including: 06:00–18:00(FR12),18:00–19:30(EOD-FR1.5),18:00–18:30(EOD-FR0.5),and control that without supplemental FR light.The results showed that supplemental FR light significantly stimulated stem elongation thereby resulting in longer plants compared with the control.Moreover,FR light altered leaf morphology toward higher leaf length/width ratio and larger leaf area.The altered plant architecture in FR supplemented plants led to a more homogeneous light distribution inside the canopy.Total plant biomass was increased by 9–16% under supplemental FR light in comparison with control,which led to 7–12% increase in ripe fruit yield.Soluble sugar content of the ripe tomato fruit was slightly decreased by longer exposure of the plants to FR light.Dry matter partitioning to different plant organs were not substantially affected by the FR light treatments.No significant differences were observed among the three FR light treatments in plant morphology as well as yield and biomass production.We conclude that under intra-canopy lighting,overhead supplemental FR light stimulates tomato growth and production.And supplementary of EOD-FR0.5 is more favorable,as it consumes less electricity but induces similar effects on plant morphology and yield.展开更多
Objective To test the effect of television viewing on pediatric obesity in urban China. Methods Stratified multistage cluster random sampling method was used for subjects selection. Nine thousand three hundred and fif...Objective To test the effect of television viewing on pediatric obesity in urban China. Methods Stratified multistage cluster random sampling method was used for subjects selection. Nine thousand three hundred and fifty-six children, as well as their parents, were investigated. Questionnaire survey was used for data collection. Children's weights and heights were measured in the clinic of the investigated kindergartens or schools by trained investigators following the standardized procedure. Results The percentages of children and adolescents who watched television less than 1 h, 1-2 h, 2-3 h and more than 3 h daily were 32.5%, 46.0%, 15.4% and 6.1%, respectively, while the prevalence of obesity was 10.9%, 11.8%, 13.2% and 15.1%, respectively. Each hourly increment of television viewing was associated with 1 %-2% increase in the prevalence of obesity. Conclusions Time spent watching television is directly related to an increase risk of obesity, television viewing time is an independent factor for pediatric obesity.展开更多
文摘Mainstream media play a crucial role in constructing the cultural memory of a city.This study used 319 short videos released by“Hi Chengdu,”a new media product of Chengdu Radio and Television,as samples.Based on the grounded theory,a research framework encompassing“content,technology,and discourse”was established to explore the paths through which mainstream media construct the cultural memory.Regarding content,this paper emphasized temporal and spatial contexts and urban spaces,delving deep into the themes of the cultural memory and vehicles for it.In terms of technology,this paper discussed the practice of leveraging audio/visual-mode discourse to stitch together the impressions of a city and evoke emotional resonance to create a“flow”of memory.As for discourse,this paper looked at the performance of a communication ritual to frame concepts and shape urban identity.It is essential to break free from conventional thinking and leverage local culture as the primary driving force to further boost a city’s productivity,in order to excel in cultural communication.
文摘Sleep quality in young adults is compromised. Instead of the recommended 7 hours, young adults’ schedule interruptions disturb sleep to a typical six and a half hours, with common disturbances in falling asleep and staying asleep. Recent literature has identified an association between academic performance, negative mood state and low activity level in young adults with sleep disturbances. Young adulthood is a time for the installation of sleep health. Both individual and schedule impositions to the young adults’ sleep schedule are to be modified to obtain Sleep Health. Recent research has identified daytime light effects on sleep such as blue light from electronics as alerting and low level light for relaxation. The aim of this study was to identify sleep quality effects with varying light exposures. It was hypothesized that bright (>450 lux) light conditions would be considered focusing and low light (<220 lux) would be considered calming. We hypothesized that sleep quality would improve by 5% with the introduction of a calm light condition. Undergraduates from a small midwestern university were invited to participate in the study in exchange for a gift card. Six participants completed the study, two males, four females all between 21 - 24 years old. Both hypotheses were supported by qualitative analysis.
文摘The rapid development of intelligent technology has led to its introduction into the field of electrical lighting in buildings.It provides more technical support for system design,use,and management,and creates a comfortable and safe living environment.The adoption of intelligent technology enables the creation of an intelligent management system,where controllers and sensors are used to adjust the light source within the building,monitor and manage the lighting system in real time,monitor the energy consumption and safety of the system,and achieve the goal of energy saving and emission reduction.This paper briefly discusses the application and significance of intelligent technology in electrical lighting and puts forward design ideas to optimize electrical lighting and measures for lighting system management.
文摘Taking the National Experimental Teaching Demonstration Center of the Central Academy of Drama as an example,this article explores the construction and development of the National Experimental Teaching Demonstration Center for the practical teaching of drama and film and television disciplines.The article first introduces the background and importance of the demonstration center and then analyzes in depth the construction content and achievements of the demonstration center from four aspects:practical teaching philosophy,practical teaching system,practical teaching resources,and practical teaching effects.Finally,the article summarizes the experience and shortcomings of the demonstration center and proposes future development directions and suggestions.
文摘With the rapid development of electronic information technology,the Internet of Things(IoT),Internet technology,and modern communication technology,people are demanding higher standards for the building environment.Especially in modern large-scale buildings with high levels of industrialization,lighting systems should also be optimized accordingly.This article explores the application path of intelligent lighting in thermal power plants for reference.
文摘The construction and installation of street lighting is an important element in the modernization of China’s cities.Besides,it also plays an important role in raising the living standards of the people.In recent years,with the technological and economic development,smart street lighting has gradually emerged.Key functions of smart street lighting include road illumination,cultural promotion,meteorological monitoring,public broadcasting,and 5G micro-base stations.The overall quality of smart street lighting construction directly impacts the effectiveness of urban development and the city’s comprehensive growth.This paper analyzes the concept of smart street lighting,its advantages and disadvantages,the functionalities of smart street light systems,and the application of smart street lighting in urban road illumination.
文摘Currently,to effectively construct high-quality smart cities and achieve comprehensive governance goals,various industries must embrace the transformation and upgrading of traditional management methods through the integration of new technologies.Among these,landscape smart lighting serves as a crucial tool for advancing smart city development.By judiciously applying this technology,it is possible to enhance traditional lighting methods and offer people novel experiences in their daily lives.Recognizing this importance,this article analyzes and organizes the content of landscape smart lighting,delves into its system characteristics,and summarizes its principles and practices in the field of architectural engineering as practical references for application scenarios.
文摘In the context of promoting green energy transition and addressing climate change globally,solar energy,as a clean and renewable energy source,has gradually become a hot topic for research.Solar streetlight systems realize energy self-sufficiency and environment-friendly lighting by integrating photovoltaic power generation technology and efficient LED lighting technology.By comprehensively analyzing the current status of the application of solar streetlights at home and abroad,this paper discusses its technical advantages,market penetration,and challenges in its development.In terms of technical characteristics,this paper focuses on analyzing the key technologies such as energy conversion efficiency and intelligent control systems of solar streetlights.
文摘The article mainly studies the application strategy of automatic addressable single-lamp control technology in tunnel lighting.It encompasses an introduction to this technology,an analysis of the tunnel lighting system using automatic addressable single-lamp control technology,and outlines the main development direction for this technology in modern tunnel lighting.The aim is to offer insights that can inform the rational deployment of this technology,thereby enhancing the lighting control effectiveness in modern tunnels and meeting their specific lighting requirements more effectively.
文摘LED lights have been widely used in urban night space lighting in recent years as they are small,energy-saving,and efficient.This article explores the use of LEDs in bridge night space lighting and their application strategies.The aim is to offer valuable insights and references for urban planners and bridge lighting designers in China.By advancing the application of LED technology in bridge night lighting,the goal is to enhance the city’s nighttime ambiance,making the bridge an iconic landmark and a defining feature of the city.
文摘A television based multistatic radar system is described. The commercial television transmitter is used as the illuminator in the multistatic radar system. The reflected commercial television signals are measured by an array of sensors. A data processing scheme is developed that adapts to the poor signal processing ability. The innovation is focused on the construction of the observation space, which could reduce the non linearity error. The new method leads to better system stability than the traditional one. Monte Carlo simulation is utilized and compared with the traditional method.
文摘Amyotrophic lateral sclerosis is a devastating neurodegenerative disease for which the current treatment approaches remain severely limited.The principal pathological alterations of the disease include the selective degeneration of motor neurons in the brain,brainstem,and spinal cord,as well as abnormal protein deposition in the cytoplasm of neurons and glial cells.The biological markers under extensive scrutiny are predominantly located in the cerebrospinal fluid,blood,and even urine.Among these biomarke rs,neurofilament proteins and glial fibrillary acidic protein most accurately reflect the pathologic changes in the central nervous system,while creatinine and creatine kinase mainly indicate pathological alterations in the peripheral nerves and muscles.Neurofilament light chain levels serve as an indicator of neuronal axonal injury that remain stable throughout disease progression and are a promising diagnostic and prognostic biomarker with high specificity and sensitivity.However,there are challenges in using neurofilament light chain to diffe rentiate amyotrophic lateral sclerosis from other central nervous system diseases with axonal injury.Glial fibrillary acidic protein predominantly reflects the degree of neuronal demyelination and is linked to non-motor symptoms of amyotrophic lateral sclerosis such as cognitive impairment,oxygen saturation,and the glomerular filtration rate.TAR DNA-binding protein 43,a pathological protein associated with amyotrophic lateral sclerosis,is emerging as a promising biomarker,particularly with advancements in exosome-related research.Evidence is currently lacking for the value of creatinine and creatine kinase as diagnostic markers;however,they show potential in predicting disease prognosis.Despite the vigorous progress made in the identification of amyotrophic lateral sclerosis biomarkers in recent years,the quest for definitive diagnostic and prognostic biomarke rs remains a formidable challenge.This review summarizes the latest research achievements concerning blood biomarkers in amyotrophic lateral sclerosis that can provide a more direct basis for the differential diagnosis and prognostic assessment of the disease beyond a reliance on clinical manifestations and electromyography findings.
基金supported by the National Key Research&Development Program of China,Nos.2021YFC2501205(to YC),2022YFC24069004(to JL)the STI2030-Major Project,Nos.2021ZD0201101(to YC),2022ZD0211800(to YH)+2 种基金the National Natural Science Foundation of China(Major International Joint Research Project),No.82020108013(to YH)the Sino-German Center for Research Promotion,No.M-0759(to YH)a grant from Beijing Municipal Science&Technology Commission(Beijing Brain Initiative),No.Z201100005520018(to JL)。
文摘Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative diseases.However,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°C.We aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large cohort.Plasma samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline project.These samples were stored at-80°C for up to 6 years before being used in this study.Our results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage time.However,the level of total tau showed a negative correlation with sample storage time.Notably,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage time.This was not observed in individuals with cognitive impairment.Consequently,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage time.Therefore,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's disease.Furthermore,in cohort studies,it is important to consider the impact of storage time on the overall results.
基金supported by Yuan Du Scholars,Clinical Research Center of Affiliated Hospital of Shandong Second Medical University,No.2022WYFYLCYJ02Weifang Key Laboratory,Weifang Science and Technology Development Plan Project Medical Category,No.2022YX093.
文摘The cGAS–STING pathway plays an important role in ischemia-reperfusion injury in the heart,liver,brain,and kidney,but its role and mechanisms in cerebral ischemia-reperfusion injury have not been systematically reviewed.Here,we outline the components of the cGAS–STING pathway and then analyze its role in autophagy,ferroptosis,cellular pyroptosis,disequilibrium of calcium homeostasis,inflammatory responses,disruption of the blood–brain barrier,microglia transformation,and complement system activation following cerebral ischemia-reperfusion injury.We further analyze the value of cGAS–STING pathway inhibitors in the treatment of cerebral ischemia-reperfusion injury and conclude that the pathway can regulate cerebral ischemia-reperfusion injury through multiple mechanisms.Inhibition of the cGAS–STING pathway may be helpful in the treatment of cerebral ischemia-reperfusion injury.
基金supported by the National Key Research and Development Program of China (2017YFB0403902)the Young Elite Scientists Sponsorship Program by the China Association for Science and Technology (CAST,2016QNRC001)
文摘Far-red(FR) light regulates phytochrome-mediated morphological and physiological plant responses.This study aims to investigate how greenhouse tomato morphology and production response to different durations of FR light during daytime and at the end of day(EOD).High-wire tomato plants were grown under intra-canopy lighting consisting of red(peak wavelength at 640 nm) and blue(peak wavelength at 450 nm) light-emitting diodes(LEDs) with photosynthetic photon flux density(PPFD) of 144 μmol m–2 s–1 at 10 cm away from the lamps,and combined with overhead supplemental FR light(peak wavelength at 735 nm) with PPFD of 43 μmol m–2 s–1 at 20 cm below the lamps.Plants were exposed to three durations of FR supplemental lighting including: 06:00–18:00(FR12),18:00–19:30(EOD-FR1.5),18:00–18:30(EOD-FR0.5),and control that without supplemental FR light.The results showed that supplemental FR light significantly stimulated stem elongation thereby resulting in longer plants compared with the control.Moreover,FR light altered leaf morphology toward higher leaf length/width ratio and larger leaf area.The altered plant architecture in FR supplemented plants led to a more homogeneous light distribution inside the canopy.Total plant biomass was increased by 9–16% under supplemental FR light in comparison with control,which led to 7–12% increase in ripe fruit yield.Soluble sugar content of the ripe tomato fruit was slightly decreased by longer exposure of the plants to FR light.Dry matter partitioning to different plant organs were not substantially affected by the FR light treatments.No significant differences were observed among the three FR light treatments in plant morphology as well as yield and biomass production.We conclude that under intra-canopy lighting,overhead supplemental FR light stimulates tomato growth and production.And supplementary of EOD-FR0.5 is more favorable,as it consumes less electricity but induces similar effects on plant morphology and yield.
基金This research was funded by "Danone Institute China Diet Nutrition Research & Communication Grant".
文摘Objective To test the effect of television viewing on pediatric obesity in urban China. Methods Stratified multistage cluster random sampling method was used for subjects selection. Nine thousand three hundred and fifty-six children, as well as their parents, were investigated. Questionnaire survey was used for data collection. Children's weights and heights were measured in the clinic of the investigated kindergartens or schools by trained investigators following the standardized procedure. Results The percentages of children and adolescents who watched television less than 1 h, 1-2 h, 2-3 h and more than 3 h daily were 32.5%, 46.0%, 15.4% and 6.1%, respectively, while the prevalence of obesity was 10.9%, 11.8%, 13.2% and 15.1%, respectively. Each hourly increment of television viewing was associated with 1 %-2% increase in the prevalence of obesity. Conclusions Time spent watching television is directly related to an increase risk of obesity, television viewing time is an independent factor for pediatric obesity.