A new methacrylamide monomer, hexylamine methacrylamide （MAHA）, was synthesized and used in polymerizations. The homopolymer of MAHA and its copolymers were synthesized by free radical polymerization techniques with...A new methacrylamide monomer, hexylamine methacrylamide （MAHA）, was synthesized and used in polymerizations. The homopolymer of MAHA and its copolymers were synthesized by free radical polymerization techniques with N-isopropyl acrylamide （NIPAAm） in two different compositions. The quatemization of the homopolymer and copolymers were carried out using 1-bromopropane. The copolymers with NIPAAm and a low MAHA content showed temperature-responsive behavior in an aqueous environment. The lower critical solution temperatures （LCSTs） of these polymers varied between 32℃ and 44℃. The LCSTs of quatemized copolymers were higher than those of neutral copolymers because they were more hydrophilic. The obtained homopolymers and copolymers were tested for antibacterial activities against S. aureus and E. coli. The quatemized water-soluble copolymers showed antibacterial activities against S. aureus. The quaternization resulted in the synthesis of both antibacterial and temperature-responsive copolymers.展开更多
基金supported by the National Science Council of Taiwan(Grant NSC 96-2815-C-168-002-E)
文摘A new methacrylamide monomer, hexylamine methacrylamide （MAHA）, was synthesized and used in polymerizations. The homopolymer of MAHA and its copolymers were synthesized by free radical polymerization techniques with N-isopropyl acrylamide （NIPAAm） in two different compositions. The quatemization of the homopolymer and copolymers were carried out using 1-bromopropane. The copolymers with NIPAAm and a low MAHA content showed temperature-responsive behavior in an aqueous environment. The lower critical solution temperatures （LCSTs） of these polymers varied between 32℃ and 44℃. The LCSTs of quatemized copolymers were higher than those of neutral copolymers because they were more hydrophilic. The obtained homopolymers and copolymers were tested for antibacterial activities against S. aureus and E. coli. The quatemized water-soluble copolymers showed antibacterial activities against S. aureus. The quaternization resulted in the synthesis of both antibacterial and temperature-responsive copolymers.
