Spatiotemporal Prediction of Urban Traffics Based on Deep GNN

Traffic prediction already plays a significant role in applications like traffic planning and urban management,but it is still difficult to capture the highly non-linear and complicated spatiotemporal correlations of traffic data.As well as to fulfil both long-termand short-termprediction objectives,a better representation of the temporal dependency and global spatial correlation of traffic data is needed.In order to do this,the Spatiotemporal Graph Neural Network(S-GNN)is proposed in this research as amethod for traffic prediction.The S-GNN simultaneously accepts various traffic data as inputs and investigates the non-linear correlations between the variables.In terms of modelling,the road network is initially represented as a spatiotemporal directed graph,with the features of the samples at the time step being captured by a convolution module.In order to assign varying attention weights to various adjacent area nodes of the target node,the adjacent areas information of nodes in the road network is then aggregated using a graph network.The data is output using a fully connected layer at the end.The findings show that S-GNN can improve short-and long-term traffic prediction accuracy to a greater extent;in comparison to the control model,the RMSE of S-GNN is reduced by about 0.571 to 9.288 and the MAE(Mean Absolute Error)by about 0.314 to 7.678.The experimental results on two real datasets,Pe MSD7(M)and PEMS-BAY,also support this claim.

Layer chicken microbiota:a comprehensive analysis of spatial and temporal dynamics across all major gut sections

Background The gut microbiota influences chicken health,welfare,and productivity.A diverse and balanced microbiota has been associated with improved growth,efficient feed utilisation,a well-developed immune system,disease resistance,and stress tolerance in chickens.Previous studies on chicken gut microbiota have predominantly focused on broiler chickens and have usually been limited to one or two sections of the digestive system,under con-trolled research environments,and often sampled at a single time point.To extend these studies,this investigation examined the microbiota of commercially raised layer chickens across all major gut sections of the digestive system and with regular sampling from rearing to the end of production at 80 weeks.The aim was to build a detailed picture of microbiota development across the entire digestive system of layer chickens and study spatial and temporal dynamics.Results The taxonomic composition of gut microbiota differed significantly between birds in the rearing and pro-duction stages,indicating a shift after laying onset.Similar microbiota compositions were observed between proven-triculus and gizzard,as well as between jejunum and ileum,likely due to their anatomical proximity.Lactobacil-lus dominated the upper gut in pullets and the lower gut in older birds.The oesophagus had a high proportion of Proteobacteria,including opportunistic pathogens such as Gallibacterium.Relative abundance of Gallibacterium increased after peak production in multiple gut sections.Aeriscardovia was enriched in the late-lay phase compared to younger birds in multiple gut sections.Age influenced microbial richness and diversity in different organs.The upper gut showed decreased diversity over time,possibly influenced by dietary changes,while the lower gut,specifi-cally cecum and colon,displayed increased richness as birds matured.However,age-related changes were inconsist-ent across all organs,suggesting the influence of organ-specific factors in microbiota maturation.Conclusion Addressing a gap in previous research,this study explored the microbiota across all major gut sections and tracked their dynamics from rearing to the end of the production cycle in commercially raised layer chickens.This study provides a comprehensive understanding of microbiota structure and development which help to develop targeted strategies to optimise gut health and overall productivity in poultry production.

Enhancing quantum temporal steering via frequency modulation

Various strategies have been proposed to harness and protect space-like quantum correlations in different models under decoherence.However,little attention has been given to temporal-like correlations,such as quantum temporal steering(TS),in this context.In this work,we investigate TS in a frequency-modulated two-level system coupled to a zero-temperature reservoir in both the weak and strong coupling regimes.We analyze the impact of various frequency-modulated parameters on the behavior of TS and non-Markovian.The results demonstrate that appropriate frequency-modulated parameters can enhance the TS of the two-level system,regardless of whether the system is experiencing Markovian or non-Markovian dynamics.Furthermore,a suitable ratio between modulation strength and frequency(i.e.,all zeroes of the 0th Bessel function J_(0)(δ/?))can significantly enhance TS in the strong coupling regime.These findings indicate that efficient and effective manipulation of quantum TS can be achieved through a frequency-modulated approach.

Temporal and Spatial Dynamics of Vaccine-Derived Poliovirus (VDPV) in Democratic Republic of Congo from 2018 to 2023

Background: The Democratic Republic of Congo (DRC) has been facing outbreaks of VDPV since 2017. These wild poliovirus variants are responsible for poliomyelitis, which is in the process of eradication.. In the following lines, we try to show the evolution of VDPV cases across the country in order to understand their chronological dynamics and seasonal influence. Methods: We conducted a cross-sectional study of of VDPV notified in the DRC from 2018 to 2023. Maps of the spatial dynamics of VDPV cases were produced from attack rates with QGIS® (3.22.8). As for temporal dynamics, time series were decomposed and presented in the form of graphs showing the chronological evolution of VDPV cases and their seasonal trend, using R.4.0 software package. Results: A total of 1196 Cases of VDPV types 1, 2 and 3 were recorded in the biological confirmation databases of the INRB and the Expanded Program of Immunization during the study period across25 provinces. The eastern part of the country reporting the most cases. The general trend is upwards, with a peak in 2022 of 527 cases, whereas in 2021 there was a notable drop of 31 cases. Analysis of the temporal breakdown suggests a seasonal pattern, with peaks between the months of September and December, considered being rainy periods in some provinces. Conclusion: During the 6 years of our study (2018 - 2023) almost all the Health Zones were hit by VDPV epidemics. The eastern part was the most impacted. The seasonal component is well marked suggesting a rise in detection in the rainy season and during pivotal periods of climate change.

Spatio-Temporal Trend and Geographic Disparity of Infertility Prevalence in Burkina Faso, 2011 to 2020

Background: Infertility affected 10% to 25% of couples globally, and about half of the infertility cases were reported in sub-Saharan Africa. Infertility poses significant social, cultural, and health challenges, particularly for women who often face stigmatization. However, comprehensive and nationally representative data, including prevalence, temporal trends, and risk factors, are lacking, prompting a study in Burkina Faso to address the need for informed policies and programs in infertility care and management. Objectives: This study aims to better understand the spatiotemporal trend of infertility prevalence in Burkina Faso. Methodology: This is a retrospective population-based study of women infertility from healthcare facilities in Burkina Faso, during January 2011 to December 2020. We calculated the prevalence rates of infertility and two disparity measures, and examined the spatiotemporal trend of infertility. Results: Over the 10-year period (2011 to 2020), 143,421 infertility cases were recorded in Burkina Faso healthcare facilities, resulting of a mean prevalence rate of 3.61‰ among childbearing age women and 17.87‰ among women who consulted healthcare facilities for reproductive issues (except contraception). The findings revealed a significant increase of infertility, with the prevalence rate varied from 2.75‰ in 2011 to 4.62‰ in 2020 among childbearing age women and from 13.38‰ in 2011 to 26.28‰ in 2020 among women who consulted healthcare facilities for reproductive issues, corresponding to an estimate annual percentage change of 8.31% and 9.80% respectively. There were significant temporal and geographic variations in the prevalence of infertility. While relative geographic disparity decreased, absolute geographic disparity showed an increasing trend over time. Conclusion: The study highlights an increasing trend of infertility prevalence and significant geographic variation in Burkina Faso, underscoring the urgent necessity for etiologic research on risk factors, psychosocial implications, and economic consequences to inform effective interventions and mitigate the socioeconomic impact of infertility.

Analysis of the spatiotemporal trends and influencing factors of Hyphantria cunea in China

In recent years,the situation of the Hyphantria cunea(Drury)(Lepidoptera:Erebidae),infestation in China has been serious and has a tendency to continue to spread.A comprehensive analysis was carried out to examine the spa-tial distribution trends and influencing factors of H.cunea.This analysis involved integrating administrative division and boundary data,distribution data of H.cunea,and envi-ronmental variables for 2021.GeoDetector and gravity analysis techniques were employed for data processing and interpretation.The results show that H.cunea exhibited high aggregation patterns in 2021 and 2022 concentrated mainly in eastern China.During these years,the focal point of the infestation was in Shandong Province with a spread towards the northeast.Conditions such as high vegetation density in eastern China provided favorable situations for growth and development of H.cunea.In China,the spatial distribution of the moth is primarily influenced by two critical factors:precipitation during the driest month and elevation.These play a pivotal role in determining the spread of the species.Based on these results,suggestions are provided for a mul-tifaceted approach to prevention and control of H.cunea infestation.

Spatial compartmentalization and temporal stability of associated microbiota in Pacific oyster Crassostrea gigas

The Pacific oyster Crassostrea gigas,one of the most exploited molluscs in the world,has suffered from massive mortality in recent decades,and the occurrence mechanisms have not been well characterized.In this study,to reveal the relationship of associated microbiota to the fitness of oysters,temporal dynamics of microbiota in the gill,hemolymph,and hepatopancreas of C.gigas during April 2018-January 2019 were investigated by 16 S rRNA gene sequencing.The microbiota in C.gigas exhibited tissue heterogeneity,of which Spirochaetaceae was dominant in the gill and hemolymph while Mycoplasmataceae enriched in the hepatopancreas.Co-occurrence network demonstrated that the gill microbiota exhibited higher inter-taxon connectivity while the hemolymph microbiota had more modules.The richness(Chao 1 index)and diversity(Shannon index)of microbial community in each tissue showed no significant seasonal variations,except for the hepatopancreas having a higher richness in the autumn.Similarly,beta diversity analysis indicated a relatively stable microbiota in each tissue during the sampling period,showing relative abundance of the dominant taxa exhibiting temporal dynamics.Results indicate that the microbial community in C.gigas showed a tissue-specific stability with temporal dynamics in the composition,which might be essential for the tissue functioning and environmental adaption in oysters.This work provides a baseline microbiota in C.gigas and is helpful for the understanding of host-microbiota interaction in oysters.

VUV imaging of type-ⅠELM filamentary structures and their temporal characteristics on EAST

In the H-mode experiments conducted on the Experimental Advanced Superconducting Tokamak(EAST),fluctuations induced by the so-called edge localized modes(ELMs)are captured by a high-speed vacuum ultraviolet(VUV)imaging system.Clear field line-aligned filamentary structures are analyzed in this work.Ion transport induced by ELM filaments in the scrape-off layer(SOL)under different discharge conditions is analyzed by comparing the VUV signals with the divertor probe signals.It is found that convective transport along open field lines towards the divertor target dominates the parallel ion particle transport mechanism during ELMs.The toroidal mode number of the filamentary structure derived from the VUV images increases with the electron density pedestal height.The analysis of the toroidal distribution characteristics during ELM bursts reveals toroidal asymmetry.The influence of resonance magnetic perturbation(RMP)on the ELM size is also analyzed using VUV imaging data.When the phase difference of the coil changes periodically,the widths of the filaments change as well.Additionally,the temporal evolution of the ELMs on the VUV signals provides rise time and decay time for each single ELM event,and the results indicate a negative correlation trend between these two times.

Computational temporal ghost imaging based on complementary modulation

We report an experimental demonstration of temporal ghost imaging in which a digital micromirror device(DMD)and+1/-1 binary modulation have been combined to give an accurate reconstruction of a nonperiodic time object.Compared to the 0/1 modulation,the reconstruction signal can be improved greatly by+1/-1 binary modulation even with half of the measurements.Experimental results show that 0/1 binary temporal objects up to 4 kHz and sinusoidal time objects up to 1 kHz can be reconstructed by this method.The influences of modulation speed and array detector gray levels are also discussed.

Cognitive Disorders, Depression and Anxiety in Temporal Lobe Epilepsy: An Overview

Partial epilepsies, originating in a specific brain region, affect about 60% of adults with epilepsy. Temporal lobe epilepsy (TLE) is the most prevalent subtype within this category, often necessitating surgical intervention due to its refractoriness to antiepileptic drugs (AEDs). Hippocampal sclerosis, a common underlying pathology, often exacerbates the severity by introducing cognitive and emotional challenges. This review delves deeper into the cognitive profile of TLE, along with the risk factors for cognitive disorders, depression, and anxiety in this population.

Elevational and temporal patterns of pollination success in distylous and homostylous buckwheats(Fagopyrum)in the Hengduan Mountains

Reproductive strategies of sexually dimorphic plants vary in response to the environment.Here,we ask whether the sexual systems of Fagopyrum species(i.e.,selfing homostylous and out-crossing distylous)represent distinct adaptive strategies to increase reproductive success in changing alpine environments.To answer this question,we determined how spatial and temporal factors(e.g.,elevation and peak flowering time)affect reproductive success(i.e.,stigmatic pollen load)in nine wild Fagopyrum species(seven distylous and two homostylous)among 28 populations along an elevation gradient of 1299-3315 m in the Hengduan Mountains,southwestern China.We also observed pollinators and conducted hundreds of hand pollinations to investigate inter/intra-morph compatibility,self-compatibility and pollen limitation in four Fagopyrum species(two distylous and two homostylous).We found that Fagopyrum species at higher elevation generally had bigger flowers and more stigmatic pollen loads;lateflowering individuals had smaller flowers and lower pollen deposition.Stigmatic pollen deposition was more variable in distylous species than in homostylous species.Although seed set was not pollenlimited in all species,we found that fruit set was much lower in distylous species,which rely on frequent pollinator visits,than in homostylous species capable of autonomous self-pollination.Our findings that pollination success increases at high elevations and decreases during the flowering season suggest that distylous and homostylous species have spatially and temporally distinct reproductive strategies related to environment-dependent pollinator activity.

Effect of gas components on the postdischarge temporal behavior of OH and O of a non-equilibrium atmospheric pressure plasma driven by nanosecond voltage pulses

OH radicals and O atoms are two of the most important reactive species of non-equilibrium atmospheric pressure plasma(NAPP),which plays an important role in applications such as plasma medicine.However,experimental studies on how the gas content affects the postdischarge temporal evolutions of OH and O in the noble gas ns-NAPP are very limited.In this work,the effect of the percentages of O_(2),N_(2),and H_(2)O on the amounts of OH and O productions and their post-discharge temporal behaviors in ns-NAPP is investigated by laser-induced fluorescence(LIF)method.The results show that the productions of OH and O increase and then decrease with the increase of O_(2)percentage.Both OH and O densities reach their maximum when about 0.8%O_(2)is added.Further increase of the O_(2)concentration results in a decrease of the initial densities of both OH and O,and leads to their faster decay.The increase of N_(2)percentage also results in the increase and then decrease of the OH and O densities,but the change is smaller.Furthermore,when the H_(2)O concentration is increased from 100 to 3000 ppm,the initial OH density increases slightly,but the OH density decays much faster,while the initial density of O decreases with the increase of the H_(2)O concentration.After analysis,it is found that OH and O are mainly produced through electron collisional dissociation.O(^(1)D)is critical for OH generation.O_(3)accelerates the consumption processes of OH and O at high O_(2)percentage.The addition of H_(2)O in the NAPP considerably enhances the electronegativity,while it decreases the overall plasma reactivity,accelerates the decay of OH,and reduces the O atom density.

Geographically and Temporally Weighted Regression in Assessing Dengue Fever Spread Factors in Yunnan Border Regions

Objective This study employs the Geographically and Temporally Weighted Regression(GTWR)model to assess the impact of meteorological elements and imported cases on dengue fever outbreaks,emphasizing the spatial-temporal variability of these factors in border regions.Methods We conducted a descriptive analysis of dengue fever’s temporal-spatial distribution in Yunnan border areas.Utilizing annual data from 2013 to 2019,with each county in the Yunnan border serving as a spatial unit,we constructed a GTWR model to investigate the determinants of dengue fever and their spatio-temporal heterogeneity in this region.Results The GTWR model,proving more effective than Ordinary Least Squares(OLS)analysis,identified significant spatial and temporal heterogeneity in factors influencing dengue fever’s spread along the Yunnan border.Notably,the GTWR model revealed a substantial variation in the relationship between indigenous dengue fever incidence,meteorological variables,and imported cases across different counties.Conclusion In the Yunnan border areas,local dengue incidence is affected by temperature,humidity,precipitation,wind speed,and imported cases,with these factors’influence exhibiting notable spatial and temporal variation.

TSCND:Temporal Subsequence-Based Convolutional Network with Difference for Time Series Forecasting

Time series forecasting plays an important role in various fields, such as energy, finance, transport, and weather. Temporal convolutional networks (TCNs) based on dilated causal convolution have been widely used in time series forecasting. However, two problems weaken the performance of TCNs. One is that in dilated casual convolution, causal convolution leads to the receptive fields of outputs being concentrated in the earlier part of the input sequence, whereas the recent input information will be severely lost. The other is that the distribution shift problem in time series has not been adequately solved. To address the first problem, we propose a subsequence-based dilated convolution method (SDC). By using multiple convolutional filters to convolve elements of neighboring subsequences, the method extracts temporal features from a growing receptive field via a growing subsequence rather than a single element. Ultimately, the receptive field of each output element can cover the whole input sequence. To address the second problem, we propose a difference and compensation method (DCM). The method reduces the discrepancies between and within the input sequences by difference operations and then compensates the outputs for the information lost due to difference operations. Based on SDC and DCM, we further construct a temporal subsequence-based convolutional network with difference (TSCND) for time series forecasting. The experimental results show that TSCND can reduce prediction mean squared error by 7.3% and save runtime, compared with state-of-the-art models and vanilla TCN.

TCAS-PINN:Physics-informed neural networks with a novel temporal causality-based adaptive sampling method

Physics-informed neural networks(PINNs)have become an attractive machine learning framework for obtaining solutions to partial differential equations(PDEs).PINNs embed initial,boundary,and PDE constraints into the loss function.The performance of PINNs is generally affected by both training and sampling.Specifically,training methods focus on how to overcome the training difficulties caused by the special PDE residual loss of PINNs,and sampling methods are concerned with the location and distribution of the sampling points upon which evaluations of PDE residual loss are accomplished.However,a common problem among these original PINNs is that they omit special temporal information utilization during the training or sampling stages when dealing with an important PDE category,namely,time-dependent PDEs,where temporal information plays a key role in the algorithms used.There is one method,called Causal PINN,that considers temporal causality at the training level but not special temporal utilization at the sampling level.Incorporating temporal knowledge into sampling remains to be studied.To fill this gap,we propose a novel temporal causality-based adaptive sampling method that dynamically determines the sampling ratio according to both PDE residual and temporal causality.By designing a sampling ratio determined by both residual loss and temporal causality to control the number and location of sampled points in each temporal sub-domain,we provide a practical solution by incorporating temporal information into sampling.Numerical experiments of several nonlinear time-dependent PDEs,including the Cahn–Hilliard,Korteweg–de Vries,Allen–Cahn and wave equations,show that our proposed sampling method can improve the performance.We demonstrate that using such a relatively simple sampling method can improve prediction performance by up to two orders of magnitude compared with the results from other methods,especially when points are limited.

Spatial and temporal variation of water clarity in typical reservoirs in the Beijing-Tianjin-Hebei region observed by GF 1-WFV satellite data

Rapidly monitoring regional water quality and the changing trend is of great practical and scientific significance,especially for the Beijing-Tianjin-Hebei(BTH)region of China where water resources are relatively scarce and inland water bodies are generally small.The remote sensing data of the GF 1 satellite launched in 2013 have characteristics of high spatial and temporal resolution,which can be used for the dynamic monitoring of the water environment in small lakes and reservoirs.However,the water quality remote sensing monitoring model based on the GF 1 satellite data for lakes and reservoirs in BTH is still lacking because of the considerable differences in the optical characteristics of the lakes and reservoirs.In this paper,the typical reservoirs in BTH-Guanting Reservoir,Yuqiao Reservoir,Panjiakou Reservoir,and Daheiting Reservoir are taken as the study areas.In the atmospheric correction of GF 1-WFV,the relative radiation normalized atmospheric correction was adopted after comparing it with other methods,such as 6 S and FLAASH.In the water clarity retrieval,a water color hue angle based model was proposed and outperformed other available published models,with the R 2 of 0.74 and MRE of 31.7%.The clarity products of the four typical reservoirs in the BTH region in 2013-2019 were produced using the GF 1-WFV data.Based on the products,temporal and spatial changes in clarity were analyzed,and the main influencing factors for each water body were discussed.It was found that the clarity of Guanting,Daheiting,and Panjiakou reservoirs showed an upward trend during this period,while that of Yuqiao Reservoir showed a downward trend.In the influencing factors,the water level of the water bodies can be an important factor related to the water clarity changes in this region.

Spatiotemporal Distributions of Bacterioplankton Communities in the Qiantang River(Hangzhou Section),China

The spatial and temporal distribution of bacterioplankton communities plays a vital role in understanding the ecological dynamics and health of aquatic ecosystems.In this study,we conducted a comprehensive investigation of the bacterioplankton communities in the Qiantang River(Hangzhou section).Water samples were collected quarterly from seven sites over a one-year period.Physical and chemical parameters,including dissolved oxygen(DO),water temperature(WT),chemical oxygen demand(COD),nitrite(NO_(2)^(-)),active phosphate(PO_(4)^(3-))and other indices were determined.In this study,theαdiversity,βdiversity and abundance differences of bacterial communities were investigated using 16S rRNA high-throughput sequencing analysis.The spatial and temporal distribution characteristics and main driving factors of the bacterioplankton community structure and diversity were discussed.The results showed that a total of 57 phyla were detected in the bacterioplankton community,among which Proteobacteria and Actinomycetes were the two dominant groups with the highest relative abundance.The results of PCoA based on Bray-Curtis distance showed that the sampling season had a slightly greater effect on the changes in bacterioplankton community structure in the Qiantang River.Mantel and partial Mantel test showed that environmental variables(Mantel r=0.6739,P<0.0001;partial Mantel r=0.507,P=0.0001)were more important than geographical distance(Mantel r=0.5322,P<0.001;partial Mantel r=0.1563,P=0.001).The distance attenuation model showed that there was significant distance attenuation in all four seasons,and the maximum limit of bacterial community diffusion was found in spring.RDA analysis showed that nine environmental factors,including COD,WT and DO,significantly affected community distribution(P<0.05).This study provides valuable insights into the spatial and temporal distribution characteristics of bacterioplankton communities,shedding light on their ecological roles in the Qiantang River.The information obtained can guide future research on the interactions between bacterioplankton and their environment,enabling the development of effective conservation strategies and sustainable management practices for aquatic ecosystems.

Multi-Stream Temporally Enhanced Network for Video Salient Object Detection

Video salient object detection(VSOD)aims at locating the most attractive objects in a video by exploring the spatial and temporal features.VSOD poses a challenging task in computer vision,as it involves processing complex spatial data that is also influenced by temporal dynamics.Despite the progress made in existing VSOD models,they still struggle in scenes of great background diversity within and between frames.Additionally,they encounter difficulties related to accumulated noise and high time consumption during the extraction of temporal features over a long-term duration.We propose a multi-stream temporal enhanced network(MSTENet)to address these problems.It investigates saliency cues collaboration in the spatial domain with a multi-stream structure to deal with the great background diversity challenge.A straightforward,yet efficient approach for temporal feature extraction is developed to avoid the accumulative noises and reduce time consumption.The distinction between MSTENet and other VSOD methods stems from its incorporation of both foreground supervision and background supervision,facilitating enhanced extraction of collaborative saliency cues.Another notable differentiation is the innovative integration of spatial and temporal features,wherein the temporal module is integrated into the multi-stream structure,enabling comprehensive spatial-temporal interactions within an end-to-end framework.Extensive experimental results demonstrate that the proposed method achieves state-of-the-art performance on five benchmark datasets while maintaining a real-time speed of 27 fps(Titan XP).Our code and models are available at https://github.com/RuJiaLe/MSTENet.

Deep reinforcement learning using least-squares truncated temporal-difference

Policy evaluation(PE)is a critical sub-problem in reinforcement learning,which estimates the value function for a given policy and can be used for policy improvement.However,there still exist some limitations in current PE methods,such as low sample efficiency and local convergence,especially on complex tasks.In this study,a novel PE algorithm called Least-Squares Truncated Temporal-Difference learning(LST2D)is proposed.In LST2D,an adaptive truncation mechanism is designed,which effectively takes advantage of the fast convergence property of Least-Squares Temporal Difference learning and the asymptotic convergence property of Temporal Difference learning(TD).Then,two feature pre-training methods are utilised to improve the approximation ability of LST2D.Furthermore,an Actor-Critic algorithm based on LST2D and pre-trained feature representations(ACLPF)is proposed,where LST2D is integrated into the critic network to improve learning-prediction efficiency.Comprehensive simulation studies were conducted on four robotic tasks,and the corresponding results illustrate the effectiveness of LST2D.The proposed ACLPF algorithm outperformed DQN,ACER and PPO in terms of sample efficiency and stability,which demonstrated that LST2D can be applied to online learning control problems by incorporating it into the actor-critic architecture.

Enhanced Temporal Correlation for Universal Lesion Detection

Universal lesion detection(ULD)methods for computed tomography(CT)images play a vital role in the modern clinical medicine and intelligent automation.It is well known that single 2D CT slices lack spatial-temporal characteristics and contextual information compared to 3D CT blocks.However,3D CT blocks necessitate significantly higher hardware resources during the learning phase.Therefore,efficiently exploiting temporal correlation and spatial-temporal features of 2D CT slices is crucial for ULD tasks.In this paper,we propose a ULD network with the enhanced temporal correlation for this purpose,named TCE-Net.The designed TCE module is applied to enrich the discriminate feature representation of multiple sequential CT slices.Besides,we employ multi-scale feature maps to facilitate the localization and detection of lesions in various sizes.Extensive experiments are conducted on the DeepLesion benchmark demonstrate that thismethod achieves 66.84%and 78.18%for FS@0.5 and FS@1.0,respectively,outperforming compared state-of-the-art methods.