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Numerical Prediction of Vortex-Induced Vibrations on Top Tensioned Riser in Consideration of Internal Flow 被引量:15
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作者 郭海燕 李效民 刘晓春 《China Ocean Engineering》 SCIE EI 2008年第4期675-682,共8页
In consideration of the effect of the internal flowing fluid and the external marine environmental condition on the vortex-induced vibration (VIV) of top tensioned riser (Till), the differential equation is derive... In consideration of the effect of the internal flowing fluid and the external marine environmental condition on the vortex-induced vibration (VIV) of top tensioned riser (Till), the differential equation is derived based on work-energy principles and the riser near wake dynamics is modeled by Facchinetti' s wake oscillator model. Then Galerkin' s finite element approximation is implemented to derive the nonlinear matrix equation of the coupled equations and file corresponding numerical programs are compiled which solve the coupled equations directly in the time domain. The comparison of the predicted results with the recent experimental results and the prediction of SHEAR7 is performed. The results show the validity of the proposed method on the prediction of VIV of deep water risers. The effect of internal flow on the dynamic characteristics and dynmnic response of the riser is analyzed and several valuable conelusions are drawn. 展开更多
关键词 top tensioned riser TTR) internal flow vortex-induced vibration V/V) dynamic characteristics dynamic response
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Nonlinear Coupled in-Line and Cross-Flow Vortex-Induced Vibration Analysis of Top Tensioned Riser 被引量:4
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作者 李效民 郭海燕 孟凡顺 《China Ocean Engineering》 SCIE EI 2010年第4期749-758,共10页
The fluctuating furces of the fluid exerted on the top terrsioned riser ('FIR) in the in-line and cross-flow directions are both modeled by van del Pol wake oscillator model and the nonlinear coupled dynamics of th... The fluctuating furces of the fluid exerted on the top terrsioned riser ('FIR) in the in-line and cross-flow directions are both modeled by van del Pol wake oscillator model and the nonlinear coupled dynamics of the in-line and cross-flow vortex-induced vibrations (VIV) of the riser are analyzed in time domain in this papar. The numencal shnulation results of the riser's in-line and cross-flow displacements and curvatures are compared with experimental measurements and the comparison shows the validity of this method in modeling some main features of the riser's VIV. Finally, the effects of the riser's top tensions and internal flow velocities on the coupled vibrations of the riser are investigated. 展开更多
关键词 top tensioned riser (TFR) vortex-induced vibration (VIV) wake oscillator model in-line and cross-flowvibration
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Design and Analysis of Tapered Stress Joint for Top Tensioned Riser System 被引量:2
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作者 张日曦 张崎 黄一 《China Ocean Engineering》 SCIE EI 2012年第3期507-520,共14页
Stress Joint (SJ) plays a key role in the Top Tensioned Riser (TTR) system for deep water engineering. A preliminary design method of tapered SJ is proposed in the paper, which could help designers obtain accurate... Stress Joint (SJ) plays a key role in the Top Tensioned Riser (TTR) system for deep water engineering. A preliminary design method of tapered SJ is proposed in the paper, which could help designers obtain accurate design data. After a further sensitive analysis is carried out, the related parameters choice and control methods are recommended in the engineering practice. By taking the extreme environment conditions into consideration, the effects of bending stress reduction and curve control are analyzed, and the 3-D FE models are established by ABQOUS for numerical evaluation to verify the correctness of design results. At last, dynamic analysis and fatigue analysis, based on actual project, are carried out with designed stress joint. The analysis results prove the feasibility and guidance of this method in the practical engineering applications. 展开更多
关键词 stress joint (S J) top tensioned riser (TTR) design method parameters sensitivities dynamic analysis fatigue analysis
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Thermal instability and dynamic response analysis of a tensioned carbon nanotube under moving uniformly distributed external pressure
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作者 A.A.Yinusa M.G.Sobamowo 《Nano Materials Science》 CAS CSCD 2021年第1期75-88,共14页
Single-walled carbon nanotubes(SWCNTs)are receiving immense research attention due to their tremendous thermal,electrical,structural and mechanical properties.In this paper,an exact solution of the dynamic response of... Single-walled carbon nanotubes(SWCNTs)are receiving immense research attention due to their tremendous thermal,electrical,structural and mechanical properties.In this paper,an exact solution of the dynamic response of SWCNT with a moving uniformly distributed load is presented.The SWCNT is modelled via the theories of Bernoulli-Euler-thermal elasticity mechanics and solved using Integral transforms.The developed closed-form solution in the present work is compared with existing results and excellent agreements are established.The parametric studies show that as the magnitude of the pressure distribution at the surface increases,the deflection associated with the single walled nanotube increases at any mode whilst a corresponding increase in temperature and foundation parameter have an attenuating effect on deflection.Moreover,an increase in the Winkler parameter,as well as a decrease in the SWCNT mass increases its frequency of vibration.Furthermore,an increase in the speed of the external agent decreases the total external pressure as a result of the removal of dead loads.The present work is envisaged to improve the application of SWCNT as nanodevices for structural,electrical and mechanical systems. 展开更多
关键词 Thermal and moving external uniform pressure tensioned carbon nanotube Dynamic and stability analysis Integral transform
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Tensegrities and Tensioned Structures
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作者 MªDolores Alvarez Elipe 《Journal of Architectural Environment & Structural Engineering Research》 2020年第3期10-16,共7页
“Push-and-pull”efficient structures have been inconceivable between XVIII centuries.It is because of the incapacity of obtain an efficient behaviour of tensioned material.Since XVIII centuries,architecture developed... “Push-and-pull”efficient structures have been inconceivable between XVIII centuries.It is because of the incapacity of obtain an efficient behaviour of tensioned material.Since XVIII centuries,architecture developed some structural knowledge generating novel structural forms in the architecture and engineering that were not known before.Tensegrities and tensioned structures were studied due to the knowledge of geometry and tension.Some investigations about tensegrities and tensioned structures have been developed since that moment.Tensegrities are bar and cable structures that work only in compression or tension efforts.Bars and cables are balanced,but in appearance the growth is disorderly.Most of deployable structures are based on tensegrity systems.The research is focused in presenting a summary of tensegrities and tensioned architectures that have been used in the structural design of novel patterns.The research of adequate materials to tension efforts will be crucial in this study.The investigation presents an important state of the art that provides technical solutions to apply on novel architectures based on tensegrities and tensioned structures.The research is useful to produce the current constructive solutions based on these constructive systems. 展开更多
关键词 TENSEGRITY tensioned GEOMETRY STRUCTURE Compression Tension EFFORT
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Tensioned Metastable Fluid Detectors in Nuclear Security for Active Interrogation of Special Nuclear Materials―Part B
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作者 Jeffrey A. Webster Rusi P. Taleyarkhan 《World Journal of Nuclear Science and Technology》 2011年第3期66-76,共11页
This paper (constituting Part B) addresses active interrogation for detecting Special Nuclear Materials (SN- Ms) and includes description of the transformational Tensioned Metastable Fluid Detector (TMFD) based method... This paper (constituting Part B) addresses active interrogation for detecting Special Nuclear Materials (SN- Ms) and includes description of the transformational Tensioned Metastable Fluid Detector (TMFD) based method for optimal monitoring. One of the greatest difficulties in detection of SNMs by active interrogation is the task of distinguishing between the probing particles and the secondary particles that indicate the presence of SNMs. The TMFD’s selective insensitivity and γ photon blindness features are advantageous for alleviating this problem. The working principle of the TMFD is discussed along with its applications for security. The experimental work to date involving detection of small quantities of uranium with conventional detectors is discussed along with results of fission neutron detection. Statistically significant detection was achieved within 5 minutes of counting to ascertain and measure conclusive evidence for the presence of a 55g sample of uranium containing 235U. Results of simulations of three active detection techniques utilizing a TMFD system are presented. The process for using the TMFD to discriminate active source particles using timing and energy are described. These simulations indicate that it should be possible to utilize the TMFD system for optimal neutron-based interrogation of SNMs. 展开更多
关键词 tensioned METASTABLE FLUID DETECTOR ACTIVE INTERROGATION TMFD SNM Detection
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Approach to Determine Corrosion Propensity in Post-Tensioned Tendons with Deficient Grout
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作者 Juan Carlos Rafols Kingsley Lau +2 位作者 Ivan Lasa Mario Paredes Adel ElSafty 《Open Journal of Civil Engineering》 2013年第3期182-187,共6页
After corrosion failure of post-tensioned tendons was identified in a Florida bridge in early 2011, laboratory tests were conducted in this study on extracted sections from the failed tendons to identify the grout pro... After corrosion failure of post-tensioned tendons was identified in a Florida bridge in early 2011, laboratory tests were conducted in this study on extracted sections from the failed tendons to identify the grout properties and makeup leading to the failure and also to elucidate the mechanism of corrosion. The initial steps in identification of PT tendons with a high propensity for corrosion initiation or damaged included a detailed visual inspection and identification of voids in the grout. Voids in tendon can be a result of bleed water formation or construction problems. General characteristics of the deficient grout and corrosion behavior of steel in the affected bridge gave a first approach to assessing grout deficiency and corrosion susceptibility. However, refinements in the understanding of the mechanisms causing grout segregation and the elucidation of the role of sulfates, oxygen content, and pore water pH in corrosion development are required. 展开更多
关键词 Post tensioned GROUT Dissimilar TENDON CORROSION
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Effects of tension on vortex-induced vibration(ⅥⅤ) responses of a long tensioned cylinder in uniform flows 被引量:2
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作者 Ling Kang Fei Ge +1 位作者 Xiaodong Wu Youshi Hong 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2017年第1期1-9,共9页
The effects of tension on vortex-induced vibration (VIV) responses for a tension-dominated long cylinder with an aspect ratio of 550 in uniform flows are experimentally investigated in this paper. The results show tha... The effects of tension on vortex-induced vibration (VIV) responses for a tension-dominated long cylinder with an aspect ratio of 550 in uniform flows are experimentally investigated in this paper. The results show that elevated tension suppresses fluctuations of maximum displacement with respect to flow velocity and makes chaotic VIV more likely to appear. With respect to periodic VIV, if elevated tension is applied, the dominant vibration frequency in the in-line (IL) direction will switch from a fundamental vibration frequency to twice the value of the fundamental vibration frequency, which results in a ratio of the dominant vibration frequency in the IL direction to that in the cross-flow direction of 2.0. The suppression of the elevated tension in the fluctuation of the maximum displacement causes the axial tension to become an active control parameter for the VIV maximum displacement of a tension-dominated long riser or tether of an engineering structure in deep oceans. However, the axial tension must be optimized before being used since the high dominant vibration frequency due to the elevated tension may unfavorably affect the fatigue life of the riser or tether. 展开更多
关键词 Tension effect Maximum displacement Dominant vibration frequency CHAOS
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Research on Anti-Fluctuation Control of Winding Tension System Based on Feedforward Compensation
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作者 Yujie Duan Jianguo Liang +4 位作者 Jianglin Liu Haifeng Gao Yinhui Li Jinzhu Zhang Xinyu Wen 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第5期1239-1261,共23页
In the fiber winding process,strong disturbance,uncertainty,strong coupling,and fiber friction complicate the winding constant tension control.In order to effectively reduce the influence of these problems on the tens... In the fiber winding process,strong disturbance,uncertainty,strong coupling,and fiber friction complicate the winding constant tension control.In order to effectively reduce the influence of these problems on the tension output,this paper proposed a tension fluctuation rejection strategy based on feedforward compensation.In addition to the bias harmonic curve of the unknown state,the tension fluctuation also contains the influence of bounded noise.A tension fluctuation observer(TFO)is designed to cancel the uncertain periodic signal,in which the frequency generator is used to estimate the critical parameter information.Then,the fluctuation signal is reconstructed by a third-order auxiliary filter.The estimated signal feedforward compensates for the actual tension fluctuation.Furthermore,a time-varying parameters fractional-order PID controller(TPFOPID)is realized to attenuate the bounded noise in the fluctuation.Finally,TPFOPID is enhanced by TFO and applied to control a tension control system considering multi-source disturbances.The stability of the method is analyzed by using the Lyapunov theorem.Finally,numerical simulations verify that the proposed scheme improves the tracking ability and robustness of the system in response to tension fluctuations. 展开更多
关键词 Constant tension control anti-fluctuation strategy tension fluctuation observer time-varying parameters fractional-order PID controller feedforward compensate
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Neurophysiological, histological, and behavioral characterization of animal models of distraction spinal cord injury: a systematic review
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作者 Bo Han Weishi Liang +4 位作者 Yong Hai Duan Sun Hongtao Ding Yihan Yang Peng Yin 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第3期563-570,共8页
Distraction spinal cord injury is caused by some degree of distraction or longitudinal tension on the spinal cord and commonly occurs in patients who undergo corrective operation for severe spinal deformity.With the i... Distraction spinal cord injury is caused by some degree of distraction or longitudinal tension on the spinal cord and commonly occurs in patients who undergo corrective operation for severe spinal deformity.With the increased degree and duration of distraction,spinal cord injuries become more serious in terms of their neurophysiology,histology,and behavior.Very few studies have been published on the specific characteristics of distraction spinal cord injury.In this study,we systematically review 22 related studies involving animal models of distraction spinal cord injury,focusing particularly on the neurophysiological,histological,and behavioral characteristics of this disease.In addition,we summarize the mechanisms underlying primary and secondary injuries caused by distraction spinal cord injury and clarify the effects of different degrees and durations of distraction on the primary injuries associated with spinal cord injury.We provide new concepts for the establishment of a model of distraction spinal cord injury and related basic research,and provide reference guidelines for the clinical diagnosis and treatment of this disease. 展开更多
关键词 animal models behavior DISTRACTION heterogeneity HISTOLOGY mechanism NEUROPHYSIOLOGY spinal cord injury systematic review tension
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Atomistic evaluation of tension–compression asymmetry in nanoscale body-centered-cubic AlCrFeCoNi high-entropy alloy
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作者 邢润龙 刘雪鹏 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第1期613-622,共10页
The tension and compression of face-centered-cubic high-entropy alloy(HEA) nanowires are significantly asymmetric, but the tension–compression asymmetry in nanoscale body-centered-cubic(BCC) HEAs is still unclear. In... The tension and compression of face-centered-cubic high-entropy alloy(HEA) nanowires are significantly asymmetric, but the tension–compression asymmetry in nanoscale body-centered-cubic(BCC) HEAs is still unclear. In this study,the tension–compression asymmetry of the BCC Al Cr Fe Co Ni HEA nanowire is investigated using molecular dynamics simulations. The results show a significant asymmetry in both the yield and flow stresses, with BCC HEA nanowire stronger under compression than under tension. The strength asymmetry originates from the completely different deformation mechanisms in tension and compression. In compression, atomic amorphization dominates plastic deformation and contributes to the strengthening, while in tension, deformation twinning prevails and weakens the HEA nanowire.The tension–compression asymmetry exhibits a clear trend of increasing with the increasing nanowire cross-sectional edge length and decreasing temperature. In particular, the compressive strengths along the [001] and [111] crystallographic orientations are stronger than the tensile counterparts, while the [110] crystallographic orientation shows the exactly opposite trend. The dependences of tension–compression asymmetry on the cross-sectional edge length, crystallographic orientation,and temperature are explained in terms of the deformation behavior of HEA nanowire as well as its variations caused by the change in these influential factors. These findings may deepen our understanding of the tension–compression asymmetry of the BCC HEA nanowires. 展开更多
关键词 high-entropy alloys body-centered-cubic NANOWIRE tension–compression asymmetry atomistic simulations
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Geometry and formation mechanism of tension gashes and their implication on the hydrocarbon accumulation in the deep-seated strata of sedimentary basin:A case from Shunnan area of Tarim Basin
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作者 Yan-Nan Du Kong-You Wu +4 位作者 Yin Liu Yan-Ying Li Zi-Cheng Cao You-Wei Cui Jun Liu 《Petroleum Science》 SCIE EI CAS CSCD 2024年第1期87-99,共13页
With the theoretical and technological developments related to cratonic strike-slip faults,the Shuntuoguole Low Uplift in the Tarim Basin has attracted considerable attention recently.Affected by multi-stage tectonic ... With the theoretical and technological developments related to cratonic strike-slip faults,the Shuntuoguole Low Uplift in the Tarim Basin has attracted considerable attention recently.Affected by multi-stage tectonic movements,the strike-slip faults have controlled the distribution of hydrocarbon resources owing to the special fault characteristics and fault-related structures.In contrast,the kinematics and formation mechanism of strike-slip faults in buried sedimentary basins are difficult to investigate,limiting the discussion of these faults and hydrocarbon accumulation.In this study,we identified the characteristics of massive sigmoidal tension gashes(STGs)that formed in the Shunnan area of the Tarim Basin.High-resolution three-dimensional seismic data and attribute analyses were used to investigate their geometric and kinematic characteristics.Then,the stress state of each point of the STGs was calculated using seismic curvature attributes.Finally,the formation mechanism of the STGs and their roles in controlling hydrocarbon migration and accumulation were discussed.The results suggest that:(1)the STGs developed in the Shunnan area have a wide distribution,with a tensile fault arranged in an enéchelon pattern,showing an S-shaped bending.These STGs formed in multiple stages,and differential rotation occurred along the direction of strike-slip stress during formation.(2)Near the principal displacement zone of the strike-slip faults,the stress value of the STGs was higher,gradually decreasing at both ends.The shallow layer deformation was greater than the deep layer deformation.(3)STGs are critical for connecting source rocks,migrating oil and gas,sealing horizontally,and developing efficient reservoirs.This study not only provides seismic evidence for the formation and evolution of super large STGs,but also provides certain guidance for oil and gas exploration in this area. 展开更多
关键词 Tarim Basin Sigmoidal tension gashes Seismic attributes Shear stress calculation Formation mechanism Reservoir control
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聚酯缆动力学行为计算方法研究
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作者 康庄 隋海波 +1 位作者 艾尚茂 张岩松 《哈尔滨工程大学学报(英文版)》 CSCD 2024年第2期398-405,共8页
The dynamic stiffness of polyester rope presents a complex mechanical performance,and the search for an appropriate calculation method to simulate this property is important.Distorted simulation results eventually yie... The dynamic stiffness of polyester rope presents a complex mechanical performance,and the search for an appropriate calculation method to simulate this property is important.Distorted simulation results eventually yield inaccurate line tension and vessel offset predictions,with the inaccuracy of vessel offset being particularly large.This paper proposes a flexible calculation method for the dynamic behavior of polyester rope based on the dynamic stiffness model.A real-time varying stiffness model of polyester rope is employed to simulate tension response through rope strain monitoring.Consequently,a simulation program is developed,and related case studies are conducted to explore the differences between the proposed method and analytical procedure of the DNV standard.Orcaflex is used to simulate the results of the latter procedure for comparison.Results show the convenience and straightforwardness of the procedure in the selection of an approximate dynamic stiffness model for polyester rope,which leads to an engineering-oriented approach.However,the proposed method is related to line property,which can directly reflect the dynamic behavior of polyester rope.Thus,a flexible calculation method may provide a reference for the simulation of the dynamic response of polyester mooring systems. 展开更多
关键词 Polyester rope Dynamic stiffness model Mean tension Minimum breaking strength Case studies
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Static-to-kinematic modeling and experimental validation of tendon-driven quasi continuum manipulators with nonconstant subsegment stiffness
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作者 郑先杰 丁萌 +2 位作者 刘辽雪 王璐 郭毓 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第1期316-326,共11页
Continuum robots with high flexibility and compliance have the capability to operate in confined and cluttered environments. To enhance the load capacity while maintaining robot dexterity, we propose a novel non-const... Continuum robots with high flexibility and compliance have the capability to operate in confined and cluttered environments. To enhance the load capacity while maintaining robot dexterity, we propose a novel non-constant subsegment stiffness structure for tendon-driven quasi continuum robots(TDQCRs) comprising rigid-flexible coupling subsegments.Aiming at real-time control applications, we present a novel static-to-kinematic modeling approach to gain a comprehensive understanding of the TDQCR model. The analytical subsegment-based kinematics for the multisection manipulator is derived based on screw theory and product of exponentials formula, and the static model considering gravity loading,actuation loading, and robot constitutive laws is established. Additionally, the effect of tension attenuation caused by routing channel friction is considered in the robot statics, resulting in improved model accuracy. The root-mean-square error between the outputs of the static model and the experimental system is less than 1.63% of the arm length(0.5 m). By employing the proposed static model, a mapping of bending angles between the configuration space and the subsegment space is established. Furthermore, motion control experiments are conducted on our TDQCR system, and the results demonstrate the effectiveness of the static-to-kinematic model. 展开更多
关键词 static-to-kinematic modeling scheme tendon-driven quasi continuum robot nonconstant subsegment stiffness tension attenuation effect
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Effectivity and safety of trifocal intraocular lenses and capsular tension rings implantation for cataract patients with axial high myopia
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作者 Shan Hua Qiu-Xia Xie +1 位作者 Hu Wang Jing-Xiang Zhong 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第3期499-508,共10页
●AIM:To assess effectivity and safety of trifocal intraocular lenses(IOLs)and capsular tension rings in treating cataract patients with axial high myopia.●METHODS:A prospective nonrandomized controlled clinical tria... ●AIM:To assess effectivity and safety of trifocal intraocular lenses(IOLs)and capsular tension rings in treating cataract patients with axial high myopia.●METHODS:A prospective nonrandomized controlled clinical trial was conducted.Totally 98 eyes(74 patients)who underwent femtosecond laser-assisted cataract surgery(FLACS)with trifocal IOLs were enrolled in the study and followed up for 2y after surgery:46 eyes(33 patients)with capsular tension ring implantation in the long axial lengths(AL)group(26<AL<29 mm)and 52 eyes(41 patients)in the normal AL group(22<AL<24.5 mm).Postoperative outcomes about effectivity and safety,including the subjective and objective visual quality,and postoperative complications were assessed.●RESULTS:Uncorrected distance visual acuity at 5 m and uncorrected intermediate visual acuity at 60 and 80 cm in the long AL group were significantly worse than those in the normal AL group at 3mo postoperatively(P<0.05).The differences in reading speed,spectacle independence and potential visual complaints between the two groups were not statistically significant(P>0.05).The dysfunctional lens index and total modulation transfer function(MTF)average height were similar between the two groups.The postoperative internal coma aberrations in the axial high myopia eyes were significantly higher than that in the normal AL group(P<0.05).The total satisfaction score in the long AL group(91.32±2.76)was slightly higher than that in the normal AL group(90.36±3.47),but there was no difference(P=0.136).A statistically negative correlation was found between corrected distance visual acuity(CDVA)and dysfunctional lens index(r=-0.382,P=0.009),and between CDVA and the total MTF average height(r=-0.374,P=0.01).But there was no significant correlation between CDVA and total satisfaction score(r=0.059,P=0.696).Postoperative complications mainly presented as posterior capsular opacity(PCO),retinal detachment and cystoid macular edema.There was no difference in the incidence of fundus disease(6.5%vs 3.8%,P=0.663)or PCO(17.4%vs 7.7%,P=0.217)between the two groups at two years.●CONCLUSION:The utilization of trifocal IOL and capsular tension ring implantation is beneficial for cataract patients with axial high myopia undergoing FLACS.This approach not only ensures excellent subjective feelings and objective visual quality,but also does not increase the incidence of postoperative complications. 展开更多
关键词 trifocal intraocular lenses capsular tension ring axial high myopia CATARACT visual quality
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Neuroimaging in atypical normal tension glaucoma:debating routine implementation in the absence of classic neurological findings
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作者 Umay Güvenç Gülizar Demirok +1 位作者 Güner Üney Selma Uzman 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第3期509-517,共9页
●AIM:To assess the necessity of neuroimaging in patients with neurological or atypical findings of normal tension glaucoma(NTG)who do not exhibit typical glaucoma manifestations.●METHODS:A retrospective analysis was... ●AIM:To assess the necessity of neuroimaging in patients with neurological or atypical findings of normal tension glaucoma(NTG)who do not exhibit typical glaucoma manifestations.●METHODS:A retrospective analysis was conducted on 90 atypical NTG patients who underwent cranial magnetic resonance imaging(MRI)due to atypical symptoms.The demographic characteristics,clinical parameters,and radiological findings were recorded.●RESULTS:Among the patients,66.7%had abnormal radiology results,with the most common findings being gliosis(34.4%),sequelae of cerebrovascular events and vascular malformations(14.4%),and benign intracranial mass lesions(11%).Non-glaucomatous visual field defects were more frequently observed in patients with abnormal neuroimaging results.However,there were no significant differences in intraocular pressure,optic disc parameters,retinal nerve fiber layer thickness,and visual field indices between patients with normal and abnormal radiological results.The mean age of the patients was 58.74y.Interestingly,there was a significant age difference,with the abnormal radiology group having a higher median age(P=0.021).●CONCLUSION:The study highlights the importance of cranial imaging in older NTG patients to detect underlying pathologies and prevent misdiagnosis.It suggests that neuroimaging may be warranted in NTG patients with atypical visual field defects incompatible with glaucoma.However,routine neuroimaging in all NTG patients without classic neurological signs may not be necessary. 展开更多
关键词 normal tension glaucoma NEUROIMAGING atypical visual field defects
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Unveiling the silent link:Normal-tension glaucoma's enigmatic bond with cardiac blood flow
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作者 Prasanna Venkatesh Ramesh Arvind Kumar Morya +5 位作者 Ajanya K Aradhya Pavithra Pannerselvam Sai Thaejesvi Gopalakrishnan Shruthy Vaishali Ramesh Aji Kunnath Devadas Navaneeth Krishna 《World Journal of Cardiology》 2024年第1期10-15,共6页
This comprehensive review embarks on a captivating journey into the complex relationship between cardiology and normal-tension glaucoma(NTG),a condition that continues to baffle clinicians and researchers alike.NTG,ch... This comprehensive review embarks on a captivating journey into the complex relationship between cardiology and normal-tension glaucoma(NTG),a condition that continues to baffle clinicians and researchers alike.NTG,characterized by optic nerve damage and visual field loss despite normal intraocular pressure,has long puzzled clinicians.One emerging perspective suggests that alterations in ocular blood flow,particularly within the optic nerve head,may play a pivotal role in its pathogenesis.While NTG shares commonalities with its high-tension counterpart,its unique pathogenesis and potential ties to cardiovascular health make it a fascinating subject of exploration.It navigates through the complex web of vascular dysregulation,blood pressure and perfusion pressure,neurovascular coupling,and oxidative stress,seeking to uncover the hidden threads that tie the heart and eyes together in NTG.This review explores into the intricate mechanisms connecting cardiovascular factors to NTG,shedding light on how cardiac dynamics can influence ocular health,particularly in cases where intraocular pressure remains within the normal range.NTG's enigmatic nature,often characterized by seemingly contradictory risk factors and clinical profiles,underscores the need for a holistic approach to patient care.Drawing parallels to cardiac health,we examine into the shared vascular terrain connecting the heart and the eyes.Cardiovascular factors,including systemic blood flow,endothelial dysfunction,and microcirculatory anomalies,may exert a profound influence on ocular perfusion,impacting the delicate balance within the optic nerve head.By elucidating the subtle clues and potential associations between cardiology and NTG,this review invites clinicians to consider a broader perspective in their evaluation and management of this elusive condition.As the understanding of these connections evolves,so too may the prospects for early diagnosis and tailored interventions,ultimately enhancing the quality of life for those living with NTG. 展开更多
关键词 Normal tension glaucoma Vascular dysregulation Ocular blood flow Blood pressure Perfusion pressure Oxidative stress
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Understanding wound healing in obesity
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作者 Asha Cotterell Michelle Griffin +3 位作者 Mauricio A Downer Jennifer B Parker Derrick Wan Michael T Longaker 《World Journal of Experimental Medicine》 2024年第1期22-32,共11页
Obesity has become more prevalent in the global population.It is associated with the development of several diseases including diabetes mellitus,coronary heart disease,and metabolic syndrome.There are a multitude of f... Obesity has become more prevalent in the global population.It is associated with the development of several diseases including diabetes mellitus,coronary heart disease,and metabolic syndrome.There are a multitude of factors impacted by obesity that may contribute to poor wound healing outcomes.With millions worldwide classified as obese,it is imperative to understand wound healing in these patients.Despite advances in the understanding of wound healing in both healthy and diabetic populations,much is unknown about wound healing in obese patients.This review examines the impact of obesity on wound healing and several animal models that may be used to broaden our understanding in this area.As a growing portion of the population identifies as obese,understanding the underlying mechanisms and how to overcome poor wound healing is of the utmost importance. 展开更多
关键词 OBESITY Wound healing ADIPOKINES Tissue fibrosis Diabetes Preclinical animal models Hypertrophic skin scarring Wound tension Metabolic syndrome
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Eudragit®-PEG Nanoparticles: Physicochemical Characterization and Interfacial Tension Measurements
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作者 Papa Mady Sy Sidy Mouhamed Dieng +4 位作者 Alphonse Rodrigue Djiboune Louis Augustin Diaga Diouf Boucar Ndong Gora Mbaye Mounibé Diarra 《Open Journal of Biophysics》 2024年第2期121-131,共11页
The objectives of this study are to understand the mechanisms involved in the stabilization of water/oil interfaces by polymeric nanoparticles (NPs) (Eudragit®). Eudragit L100 NPs of various sizes and Zeta potent... The objectives of this study are to understand the mechanisms involved in the stabilization of water/oil interfaces by polymeric nanoparticles (NPs) (Eudragit®). Eudragit L100 NPs of various sizes and Zeta potentials were studied and compared at a water/cyclohexane model interface using a droplet tensiometer (Tracker Teclis, Longessaigne, France). The progressive interfacial adsorption of the NPs in the aqueous phase was monitored by tensiometry. The model interface was maintained and observed in a drop tensiometer, analyzed via axisymmetric drop shape analysis (ADSA), to determine the interfacial properties. Given the direct relationship between the stability of Pickering emulsions (emulsions stabilized by solid nanoparticles) and the interfacial properties of these layers, different nanoparticle systems were compared. Specifically, Eudragit NPs of different sizes were examined. Moreover, the reduction of the Zeta potential with PEG-6000 induces partial aggregation of the NPs (referred to as NP flocs), significantly impacting the stability of the interfacial layer. Dynamic surface tension measurements indicate a significant decrease in interfacial tension with Eudragit® nanoparticles (NPs). This reduction correlates with the size of the NPs, highlighting that this parameter does not operate in isolation. Other factors, such as the contact angle and wettability of the nanoparticles, also play a critical role. Notably, larger NPs further diminished the interfacial tension. This study enhances our understanding of the stability of Pickering emulsions stabilized by Eudragit® L100 polymeric nanoparticles. 展开更多
关键词 NANOPARTICLES Eudragit® PEG Interfacial Tension Pickering Emulsion
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Hubble Tension Explanation from This Cosmological Model AΛΩ (Slow Bang Model, SB)
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作者 Jean Perron 《Journal of High Energy Physics, Gravitation and Cosmology》 CAS 2024年第1期106-125,共20页
In this article we present a model of Hubble-Lemaître law using the notions of a transmitter (galaxy) and a receiver (MW) coupled to a model of the universe (Slow Bang Model, SB), based on a quantum approach of t... In this article we present a model of Hubble-Lemaître law using the notions of a transmitter (galaxy) and a receiver (MW) coupled to a model of the universe (Slow Bang Model, SB), based on a quantum approach of the evolution of space-time as well as an equation of state that retains all the infinitesimal terms. We find an explanation of the Hubble tension H<sub>0</sub>. Indeed, we have seen that this constant depends on the transceiver pair which can vary from the lowest observable value, from photons of the CMB (theoretical [km/s/Mpc]) to increasingly higher values depending on the earlier origin of the formation of the observed galaxy or cluster (ETG ~0.3 [Gy], ~74 [km/s/Mpc]). We have produced a theoretical table of the values of the constant according to the possible pairs of transmitter/receiver in the case where these galaxies follow the Hubble flow without large disturbance. The calculated theoretical values of the constant are in the order of magnitude of all values mentioned in past studies. Subsequently, we applied the models to 9 galaxies and COMA cluster and found that the models predict acceptable values of their distances and Hubble constant since these galaxies mainly follow the Hubble flow rather than the effects of a galaxy cluster or a group of clusters. In conclusion, we affirm that this Hubble tension does not really exist and it is rather the understanding of the meaning of this constant that is questioned. 展开更多
关键词 Model of the Universe Cosmological Constant Hubble Constant Hubble’s Tension Hubble-Lemaître Law Hubble’s Flow
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