期刊文献+

二次检索

题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息
共找到2,890篇文章
< 1 2 145 >
每页显示 20 50 100
Influence of Global Solar Radiation on Indoor Environment: Experimental Study of Internal Temperature Distribution in Two Test Cells with Different Roof Systems
1
作者 Grace Tiberio Cardoso de Seixas Francisco Vecchia 《Journal of Civil Engineering and Architecture》 2015年第1期28-37,共10页
This work is part of a large experimental study on the distribution of internal temperatures in two similar test cells, but with different systems of coverage. The main goal of this paper is to present results on an e... This work is part of a large experimental study on the distribution of internal temperatures in two similar test cells, but with different systems of coverage. The main goal of this paper is to present results on an experimental field to determine the influence of solar radiation on the internal environmental conditions of different roof systems. Dry bulb temperature and internal surface temperatures were measured in two test cells with different roof systems (green roof and conventional ceramic roof). Their thermal performances were compared on days with differing air mass domain, based on dynamic climatic approach. This research was based on the spatial and temporal approaches of dynamic climatology, from the climatic regime of the city of Itirapina, S^o Paulo State, analysed as representative episodes. Climatic data were provided by an automatic weather station and verified by satellite imagery, and the internal temperatures of the cells were collected by thermocouples installed on the surfaces of ceilings, floors, walls, and suspended inside the buildings. The results indicate that the solar radiation is mainly responsible for the great variations in temperature and its impact on indoor environments, since there were great differences in temperature inside comparing the two days of the experiment. This refutes the notion that the outside temperature is responsible for daily variations in temperature inside buildings. 展开更多
关键词 Dynamic climatology solar radiation air mass domain internal temperatures test cells.
下载PDF
Chemosensitivity Testing of Circulating Epithelial Tumor Cells (CETC) in <i>Vitro</i>: Correlation to in <i>Vivo</i>Sensitivity and Clinical Outcome
2
作者 Nadine Rudiger Ernst-Ludwig Stein +7 位作者 Erika Schill Gabriele Spitz Carola Rabenstein Martina Stauch Matthias Rengsberger Ingo B. Runnebaum Ulrich Pachmann Katharina Pachmann 《Journal of Cancer Therapy》 2013年第2期597-605,共9页
Background: Chemotherapy is a mainstay of tumor therapy, however, it is predominantly applied according to empirically developed recommendations derived from statistical relapse rates occurring years after the treatme... Background: Chemotherapy is a mainstay of tumor therapy, however, it is predominantly applied according to empirically developed recommendations derived from statistical relapse rates occurring years after the treatment in the adjuvant situation and from progression-free interval data in the metastatic situation, without any possibility of individually determining the efficacy in the adjuvant situation and with loss of time and quality of life in the metastatic situation if the drugs chosen are not effective. Here, we present a method to determine the efficiency of chemotherapeutic drugs using tumor cells circulating in blood as the part of the tumor actually available in the patient’s body for chemosensitivity testing. Methodology/Principal Findings: After only red blood cell lysis, omitting any enrichment (analogous to other blood cell enumeration methods, including rare CD34 cells), the white cells comprising the circulating epithelial tumor cells (CETC) are exposed to the drugs in question in different concentrations and for different periods of time. Staining with a fluorescence-labeled anti-epithelial antibody detects both vital and dying tumor cells, distinguishing vital from dying cells through membrane permeability and nuclear staining with propidium iodide. Increasing percentages of dying tumor cells are observed dependent on time and concentration. The sensitivity can vary during therapy and was correlated with decrease or increase in CETC and clinical outcome. Conclusions/Significance: Thus, we are able to show that chemosensitivity testing of circulating tumor cells provides real-time information about the sensitivity of the tumor present in the patient, even at different times during therapy, and correlates with treatment success. 展开更多
关键词 CIRCULATING EPITHELIAL Tumor cells Chemosensitivity testing Breast CANCER Ovarian CANCER
下载PDF
Biomarker Testing Rates in Patients with Advanced Non-Small Cell Lung Cancer Treated in the Community 被引量:2
3
作者 Eric Nadler Melissa Pavilack +2 位作者 Jamyia Clark Janet Espirito Ancilla Fernandes 《Journal of Cancer Therapy》 2019年第12期971-984,共14页
Introduction: Over the past few years, molecular targeted therapies have been?emerging for the treatment of metastatic non-small cell lung cancer (NSCLC).?Targeted therapy is associated with improved outcomes in patie... Introduction: Over the past few years, molecular targeted therapies have been?emerging for the treatment of metastatic non-small cell lung cancer (NSCLC).?Targeted therapy is associated with improved outcomes in patients with identified gene alterations, and national guidelines recommend routine biomarker testing. This study evaluated real-world rates of documented epidermal growth factor receptor (EGFR) mutation and other biomarker testing in patients with advanced NSCLC over time.?Methods: Adult patients with Stage IV NSCLC were identified between January 1, 2012 and May 31, 2017 from the US Oncology Network iKnowMedTM?electronic health records. Patients were examined overall and by histology. Rates of documented EGFR mutation and other biomarker testing were calculated. Multivariable regression analyses were conducted to identify characteristics associated with documented biomarker testing. Results: A total of 14,461 patients were identified: median age was 69.3 years, 52.3% were male, 14.6% were nonsmokers, and 64.7% had non-squamous histology.?EGFR mutation testing rates were 35.5%?overall, with an increase in rates seen over time: 30.0% in 2012 to 44.0% in 2016?(p??0.001).?Anaplastic lymphoma kinase (ALK), c-ros oncogene 1 (ROS1), and programmed death-ligand 1 (PD-L1) mutation testing rates were 32.9%, 5.7%, and 5.7%, respectively. More recent diagnosis year, non-squamous histology, larger practice size, and nonsmoking status were strongly associated with higher documented EGFR and ALK mutation testing rates.?Conclusions: EGFR mutation testing rates steadily increased over time, but remained less than 50%, with lower mutation testing rates reported for ALK, ROS1, and PD-L1, suggesting that opportunities exist to improve education on testing for biomarkers in NSCLC. 展开更多
关键词 Non-Small-cell LUNG Cancer NSCLC Biomarkers EGFR testING
下载PDF
Measurement of Ca^(2+) Flow in Cochlear Cells Using Non-Invasive Micro-Test Technique 被引量:1
4
作者 CHEN Shi-qin YU Ning +2 位作者 YE Sheng-nan YANG Shi-ming ZHAI Suo-qiang 《Journal of Otology》 2010年第2期90-96,共7页
Objective To test Calcium ion(Ca2+) flow at the head and end of outer hair cells(OHCs) in resting state and in response to Nimodipine treatment.Methods Non-invasive micro-test techniques were used to study Ca2+ in iso... Objective To test Calcium ion(Ca2+) flow at the head and end of outer hair cells(OHCs) in resting state and in response to Nimodipine treatment.Methods Non-invasive micro-test techniques were used to study Ca2+ in isolated OHCs in adult guinea pigs.Results Four types of Ca2+ transport were identified in OHCs on basilar membrane tissue fragments:influx at the head of with efflux at the bottom(type 1):efflux at the head of OHCs with influx at the bottom(type 2);influx at the both head and bottom(type 3);and efflux at the both head and bottom(type 4).However,only type 1 and type 3 of Ca2+ ion transport were detected in the cochlea.We propose that Ca2+ ion transport exists in adult guinea pig cochlear OHCs in resting state and is variable.Ca2 + flow in OHC can be inhibited by Nimodipine in resting state. 展开更多
关键词 Guinea pig outer hair cells Ca2+ ion non-invasive micro-test technique nimodipine.
下载PDF
Sensitivity of Different Cytotoxic Responses of Vero Cells Exposed to Organic Chemical Pollutants and their Reliability in the Bio-toxicity Test of Trace Chemical Pollutants
5
作者 TING-TING LIAO YAN-LING SHI JIAN-WEI JIA AND LEI WANG 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2010年第3期219-229,共11页
Objective To find a sensitive cytotoxic response to reflect the bio-toxicity of trace organic pollutants, the sensitivity and reliability of morphological change and proliferation inhibition of Vero cells exposed to 2... Objective To find a sensitive cytotoxic response to reflect the bio-toxicity of trace organic pollutants, the sensitivity and reliability of morphological change and proliferation inhibition of Vero cells exposed to 2, 4, 6-trichlorophenol (TCP) and the leachate from products related to drinking water (PRDW) were compared, and the mechanism of the morphological change in Vero cells exposed to chemical pollutants was studied. Methods Vero cells were treated by different concentration of TCP and the leachate from PRDW. Methylthiazol-2-yl-2, 5-diphenyl tetrazolium bromide (MTT) assay was carried out for proliferation inhibition. Bioluminescence method was carried out as another method to test the toxicity of TCP. Flow Cytometry assay was used to test cell Apoptosis and damage of cell-membrane. Results 0.25 mg/L TCP had an effect on cell morphology, and the proportion of morphologically changed cells increased with increasing TCP concentration. At low TCP concentrations, inhibition of cell proliferation did not seem to correlate to TCP concentration, and was negative when TCP concentration was 〈1.0 mg/L. After exposure to leachate from PRDW extracted at different temperatures, the percentage of morphologically changed cells increased with extracting temperature, but the inhibition of cell proliferation failed to reflect the correlation between extracting temperature and proliferation inhibition of Vero cells. Although the Sensitivity of bioluminescence method seems to be similar to morphological change in Veto cells, the bacterial in this method is not homologous enough with human body cells to reflect the toxicity to human body. These imply cell morphological change is a more sensitive and reliable method to reflect bio-toxicity of organic pollutants than proliferation inhibition. Flow cytometry analysis and cell rejuvenation experiments indicated cell membrane damage, which results in cell morphological change, was an early and sensitive cytotoxic response comparing with necrosis. Conelusion These results indicated that the cell membrane toxicity represented by morphological changes is a more sensitive and reliable method to indicate the composite bio-toxicity of trace chemicals than proliferation inhibition, inhibition on bioluminescence and necrosis. Nevertheless, the quantification of morphological change should be studied further. 展开更多
关键词 Vero cell Morphological change Membrane damage Bio-toxicity test Drinking water
下载PDF
Clinical Significance of Pulmonary Function Tests in Long-Term Survivors after Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation
6
作者 Kenji Matsumoto Satomi Ito +4 位作者 Wataru Yamamoto Eriko Ogusa Atsuo Maruta Yoshiaki Ishigatsubo Heiwa Kanamori 《Open Journal of Blood Diseases》 2013年第1期6-12,共7页
We retrospectively assessed long-term pulmonary function in adults surviving for ≥5 years after myeloablative allogeneic hematopoietic stem cell transplantation and identified risk factors for late-onset noninfectiou... We retrospectively assessed long-term pulmonary function in adults surviving for ≥5 years after myeloablative allogeneic hematopoietic stem cell transplantation and identified risk factors for late-onset noninfectious pulmonary complications. Among 174 patients undergoing transplantation for hematologic malignancies between May 1994 and December 2004, 81 long-term survivors were evaluated. Pulmonary function tests (PFTs) were performed before conditioning, 3 months and 1 year after transplantation, and then annually. Eight patients (10%) had abnormal pulmonary function before transplantation, but this was not associated with late changes in PFTs. Patients with chronic graft-versus-host disease (GVHD) showed a significant decline of lung function after 3 years when compared with patients without chronic GVHD. Abnormal pretransplantation lung function was associated with pulmonary chronic GVHD according to National Institutes of Health criteria (score 0, n = 58;score 1, n = 14;score 2, n = 6;score 3, n = 3). Five patients with late-onset noninfectious pulmonary complications showed a decline of lung function at 1 year after transplantation. Only chronic GVHD was significantly related to late-onset noninfectious pulmonary complications. In conclusion, abnormal lung function before transplantation may be associated with a decline in pulmonary function within 1 year after transplantation, but late-onset noninfectious pulmonary complications could not be predicted from pretransplantation lung function. 展开更多
关键词 Long-Term SURVIVOR PULMONARY Function tests LATE-ONSET Noninfectious PULMONARY COMPLICATIONS MYELOABLATIVE ALLOGENEIC Stem cell Transplantation
下载PDF
由O-cell试桩结果确定整桩的性能 被引量:7
7
作者 郑英杰 张克绪 +1 位作者 张尔其 朱占元 《岩土工程学报》 EI CAS CSCD 北大核心 2008年第9期1416-1422,共7页
提出了一个根据O-cell试桩结果确定整桩性能的途径,包括基本方法、步骤及必须的资料。以某公路大桥的O-cell试桩为例,采用本文所提出的途径确定出了桩阻力参数、相应整桩的荷载沉降曲线及极限承载力。验证了桩侧阻力与接触面两侧切向位... 提出了一个根据O-cell试桩结果确定整桩性能的途径,包括基本方法、步骤及必须的资料。以某公路大桥的O-cell试桩为例,采用本文所提出的途径确定出了桩阻力参数、相应整桩的荷载沉降曲线及极限承载力。验证了桩侧阻力与接触面两侧切向位移差之间关系可以用双曲线表示。将按本文提出的方法和现有其他四种方法确定的整桩荷载沉降曲线做了比较,并对各种确定整桩荷载沉降曲线方法的可靠性和适用性做了评价。此外,将按本文给出的整桩荷载沉降曲线和按流行公式确定的整桩极限承载力做了比较,指出了流行公式低估了整桩极限承载力,并对流行公式提出了一个修改建议。强调了,只有按某种有根据的方法确定出完整的整桩荷载沉降曲线,才能由O-cell试桩结果可靠地确定出整桩的极限承载力。 展开更多
关键词 O-cell试桩法 数值模拟分析 桩阻力 荷载沉降曲线 极限荷载
下载PDF
剪切流中Cell-Truss Spar平台涡激运动的CFD计算与模型试验研究 被引量:2
8
作者 王颖 杨建民 +1 位作者 李润培 李欣 《中国造船》 EI CSCD 北大核心 2008年第A02期251-259,共9页
目前,Spar平台在离岸深水作业中得到越来越广泛的应用,作为影响Spar平台在某些来流条件下运动响应特性的一种重要现象,涡激运动已成为国际海洋工程界亟待研究的一个新课题。本文采用CFD计算与模型试验相结合的方法,对一座称为“Cell... 目前,Spar平台在离岸深水作业中得到越来越广泛的应用,作为影响Spar平台在某些来流条件下运动响应特性的一种重要现象,涡激运动已成为国际海洋工程界亟待研究的一个新课题。本文采用CFD计算与模型试验相结合的方法,对一座称为“Cell-Truss Spar”的新型Spar平台在剪切流作用下发生涡激运动的现象进行了研究。相对于目前已存在并应用的Spar平台,Cell-Truss Spar平台在结构形式上有其自身的特征,研究中充分考虑了这一特征,对其建立适当的CFD计算模型,得到其涡激运动的特征,模拟了锁定现象的发生过程,分析了锁定现象的发生机理和规律;同时制作了精细的物理模型,测试了一系列的剪切流表面流速,得到了Cell-Truss Spar平台涡激运动的一些关键性参数,并成功地观察到了锁定现象的发生。CFD计算与模型试验相互比较,相互验证,最后对该平台涡激运动响应的特征进行了分析和总结,为进一步的涡激运动抑制研究奠定了基础。 展开更多
关键词 cell-Truss Spar 涡激运动 CFD 模型试验 折合速度
下载PDF
用Cell组件生成测试报表
9
作者 喻剑锋 刘冬 郑玉航 《微计算机信息》 2001年第2期42-44,共3页
介绍了一种 ActiveX表格控件 Cell组件,并且详细地讨论了该组件在测试报表生成中的应用。
关键词 cell组件 ACTIVEX控件 测试报表 程序设计
下载PDF
O-cell试桩法桩土共同作用的弹性理论分析 被引量:1
10
作者 罗春波 朱向荣 +1 位作者 孔清华 孙金月 《工业建筑》 CSCD 北大核心 2007年第8期60-63,共4页
基于Poulos桩顶受荷的弹性理论解,对O-cell试桩法在桩端受荷条件下桩侧摩阻力和桩身位移的弹性理论公式进行推导。通过编制相应的计算程序,给出O-cell法试桩条件下桩侧摩阻力和位移沿桩身的分布,并对桩的长径比和桩土刚度比对侧阻与位... 基于Poulos桩顶受荷的弹性理论解,对O-cell试桩法在桩端受荷条件下桩侧摩阻力和桩身位移的弹性理论公式进行推导。通过编制相应的计算程序,给出O-cell法试桩条件下桩侧摩阻力和位移沿桩身的分布,并对桩的长径比和桩土刚度比对侧阻与位移沿桩身分布的影响进行分析。 展开更多
关键词 O-cell试桩法 弹性理论法 桩侧摩阻力 桩身位移
下载PDF
雅培CELL-DYN 3700血球计数仪故障排除
11
作者 蔡美芬 《医疗设备信息》 2007年第5期81-83,共3页
介绍了雅培CELL-DYN3700血球计数仪常见故障的分析与排除。
关键词 血球计数仪 光耦合检测 纤维蛋白
下载PDF
Preparation and Optimization of Porous Membrane Electrodes via Gradient Coating in Hydrogen Fuel Cell 被引量:2
12
作者 Gu Xianrui Wu Yuchao +1 位作者 Wang Houpeng Rong Junfeng 《China Petroleum Processing & Petrochemical Technology》 SCIE CAS 2020年第3期1-8,共8页
Fuel cells are considered to be one of the ideal alternatives to traditional fossil energy conversion devices.Membrane electrodes are the core components in the hydrogen fuel cells.Our work reported the synthesis of t... Fuel cells are considered to be one of the ideal alternatives to traditional fossil energy conversion devices.Membrane electrodes are the core components in the hydrogen fuel cells.Our work reported the synthesis of the Pt/C catalysts with different Pt loading,and by changing the Nafion content,hot pressing temperature and hot pressing pressure,the catalyst coated membrane(CCM)spraying process was optimized.Moreover,the three-dimensional structure model of the single battery membrane electrode was studied quantitatively,and the porous membrane electrode with gradient distribution was fabricated under optimized processing conditions,with excellent electrical performance. 展开更多
关键词 hydrogen fuel cell membrane electrode Pt/C catalyst polarization curve power density single cell test
下载PDF
Physiological testing of blood for great bustard 被引量:1
13
作者 王进军 田秀华 +2 位作者 宋金宝 高照红 宁永强 《Journal of Forestry Research》 SCIE CAS CSCD 1998年第4期278-279,共2页
Twelve indices of blood for great bustard were determined by using JT-TR blood cell analyzer. Theyincluded white cell number, red cell number, hemoglobin density, hematocrit. mean volume of red cell, mean hemoglobin o... Twelve indices of blood for great bustard were determined by using JT-TR blood cell analyzer. Theyincluded white cell number, red cell number, hemoglobin density, hematocrit. mean volume of red cell, mean hemoglobin of red cell, mean hemoglobin density of red cell, distribution width of red cell, platelet number, platelethematocrit, mean platelet volume, and platelet distribution width. The analysis data indicated that the blood ofgreat bustard have strong function of taking oxygen. The current breeding condition is fine and suitable for thephysiological requirements of great bustard. 展开更多
关键词 GREAT bustard BLOOD testING BLOOD cell
下载PDF
Cancer Chemosensitivity Testing: Review
14
作者 Yongzhuang Su 《Journal of Cancer Therapy》 2014年第7期672-679,共8页
Since chemotherapy started in 1940s, chemosensitivity testing has been both a very attractive field and one fraught with potential pitfalls. Many methods were developed and brought initial promises, yet later ending i... Since chemotherapy started in 1940s, chemosensitivity testing has been both a very attractive field and one fraught with potential pitfalls. Many methods were developed and brought initial promises, yet later ending in disappointment and were eliminated. For example, in the 1970s clonogenic assay was generally believed to be the best testing method for predicting clinical outcome. However, technical problems including low evaluation rate limited its use. Currently, MTT, ATP, DISC and Kern’s assay hold better promises. Since the 90s, the study of molecular biology has been progressing rapidly. It accelerated the understanding of molecular mechanisms of drug response. Numerous papers were published, but only few techniques can be applied in clinical practice. This review summarizes the controversies and current progress of chemosensitivity assays based on available online information, and makes a suggestion about their future routine practice. 展开更多
关键词 CANCER CHEMOSENSITIVITY testing cell CULTURE MOLECULAR
下载PDF
O-CELL静载试桩法及其应用 被引量:3
15
作者 李增选 张莹 《建筑技术》 北大核心 2000年第3期157-159,共3页
O -CELL法是美国发明的静载试桩方法 ,其最大优点是可在试桩时量测出桩的端阻力和桩周侧摩擦力 ,具有经济、安全、方便等特点 ,但这种方法不适用于一些桩型 ,对长混凝土桩也不适用。
关键词 O-cell 静载荷试验 单桩 极限承载力 桩基
下载PDF
ASSAY OF SENSITIVITY OF CANCER CELL TO ANTICANCER DRUG IN GLASS CAPILLARIES
16
作者 贺智敏 魏立勇 彭祥鄂 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 1992年第4期43-48,共6页
A newly established human tumor clonogenecity assay - the glass capillary tube culture technique (CAP assay) to described. With this method, we observed the in vitro anticancer efficiency of several antineoplastics on... A newly established human tumor clonogenecity assay - the glass capillary tube culture technique (CAP assay) to described. With this method, we observed the in vitro anticancer efficiency of several antineoplastics on human solid tumors and acute non-lymphatic leukemia (ANLL) specimen. Comparing with the conventional two-layer agar culture assay (2-LAC assay). The CAP-assay had a higher culture success rate, higher plating efficiency (PE) and shorter experimental period. The preliminary data suggesting and that the CAP assay has the potential to replace the conventional 2- LAC assay for in vitro drug- sensitivity testing and may be applied clinically. 展开更多
关键词 glass capillary cell culture drug-sensitivity test.
下载PDF
O-Cell桩基承载力试验法在大直径超长钻孔嵌岩桩的应用
17
作者 刘亚东 李胜 史炳峰 《中国港湾建设》 2012年第3期41-44,共4页
结合某桥梁大直径超长钻孔嵌岩桩承载力测试的实践,介绍了O-Cell桩基承载力试验原理和单桩极限承载力确定方法,对于荷载箱位置的选取及超长嵌岩桩成孔成桩工艺进行分析并提出自己的看法,为类似工程提供参考。
关键词 O-cell 桩基试验 荷载箱 嵌岩桩 极限承载力
下载PDF
多胞圆管夹芯组合板落锤冲击试验及数值仿真
18
作者 吴丽丽 徐翔 +2 位作者 李远 王慧 李金鹏 《振动与冲击》 EI CSCD 北大核心 2024年第23期38-46,55,共10页
为了应对煤矿巷道冲击地压下支架结构破坏严重的问题,提出了一种多胞圆管夹芯组合板。该组合板可与煤矿巷道金属支架结合,通过溃缩变形吸能共同抵御冲击荷载。共设计了4个不同芯层厚度夹芯组合板试件的落锤冲击试验,并建立了有限元模型... 为了应对煤矿巷道冲击地压下支架结构破坏严重的问题,提出了一种多胞圆管夹芯组合板。该组合板可与煤矿巷道金属支架结合,通过溃缩变形吸能共同抵御冲击荷载。共设计了4个不同芯层厚度夹芯组合板试件的落锤冲击试验,并建立了有限元模型,基于试验验证了该数值模型,开展了多胞圆管夹芯组合板的冲击响应和吸能特性的参数分析。研究结果表明,冲击作用下,多胞圆管夹芯组合板面板呈现圆盘状凹陷,芯层胞体和十字肋发生了褶皱和下陷变形,各个腔室协同工作、相互支撑,并通过塑性变形吸能。同时底部冲击反力的峰值总是滞后且低于落锤冲击荷载峰值,在多次冲击条件下,该组合板也能展现出良好的吸能缓冲效果。多胞圆管夹芯组合板可吸收超过90.00%的冲击能量,其中65.00%以上能量由芯层结构吸收。芯层厚度从0.5 mm增加到2.0 mm,芯层部分吸收能量的占比增大了24.17%,相反面板吸能效率递减,减幅为17.17%,芯层厚度减小可降低峰值冲击荷载,芯层厚度为1.0 mm时吸能效果较好。面板厚度对吸能性能影响较小,建议其厚度选择与芯层厚度相近。冲击能量一定情况下,改变落锤质量和冲击速度对结构动力冲击性能和吸能效率的影响很小。 展开更多
关键词 落锤冲击试验 多胞圆管夹芯组合板 冲击地压 煤矿巷道 数值模拟
下载PDF
结核γ-干扰素释放检测、核酸扩增检测联合结核感染T细胞监测对肿瘤合并结核感染患者的指导意义
19
作者 王琳 张偲 +4 位作者 马小宏 程宜 宋晗 董颖 丁小红 《转化医学杂志》 2024年第3期359-362,共4页
目的 探讨结核γ-干扰素释放检测(TB-IGRA)、核酸扩增检测联合结核感染T细胞监测在肿瘤合并结核感染患者检测中的应用价值,分析其诊断能力。方法 收集2023年9月至2024年6月江苏省如皋市人民医院收治的100例肿瘤患者的资料进行回顾性分析... 目的 探讨结核γ-干扰素释放检测(TB-IGRA)、核酸扩增检测联合结核感染T细胞监测在肿瘤合并结核感染患者检测中的应用价值,分析其诊断能力。方法 收集2023年9月至2024年6月江苏省如皋市人民医院收治的100例肿瘤患者的资料进行回顾性分析,按照是否并合并结核感染分为感染组(23例)和未感染组(77例)。分析2组患者的临床资料,比较TB-IGRA、核酸扩增检测、结核感染T细胞监测3种检测技术阳性检出率差异,比较其检出能力。结果 临床细菌学检查证实肿瘤合并结核感染23例(23%),未感染77例(77%),感染组与未感染组的性别比例、年龄分布、肿瘤分类比较,差异无统计学意义(P> 0.05)。TB-IGRA检出结核菌阳性率65.22%(15/23),核酸扩增检测为47.83%(11/23),结核感染T细胞监测为55.52%(13/23)。联合应用3种检测技术时,结核菌阳性检出率为82.61%(19/23),明显高于单独检测(P <0.05)。结论 TB-IGRA检出的肿瘤合并结核感染患者的阳性率最高,3种检测技术联合应用阳性检出率明显高于单独应用,具有较好的临床应用价值。 展开更多
关键词 T细胞免疫斑点试验 γ-干扰素释放检测 核酸扩增检测 结核感染T细胞监测 肿瘤 结核感染
下载PDF
Effects of some heavy metals on cell suspension cultures of Catharanthus roseus
20
作者 Zhu Lizhong (Department of Environmental Science),Hangzhou University,Hangzhou 310028,China Cullen W.R.(Department of Chemistry,U.B.C. Vancouver,B.C.Canada V6T 1Z1) 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 1995年第1期60-65,共6页
EffectsofsomeheavymetalsoncellsuspensionculturesofCatharanthusroseusZhuLizhong(DepartmentofEnvironmentalScie... EffectsofsomeheavymetalsoncellsuspensionculturesofCatharanthusroseusZhuLizhong(DepartmentofEnvironmentalScience),HangzhouUniv... 展开更多
关键词 Catharanthus roseus cell culture heavy metals toxicity test.
下载PDF
上一页 1 2 145 下一页 到第
使用帮助 返回顶部