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Clinical characteristics of testicular torsion and factors influencing testicular salvage in children:A 12-year study in tertiary center
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作者 Xiang-Hui Gang Yuan-Yuan Duan +5 位作者 Bin Zhang Zheng-Gan Jiang Rong Zhang Jun Chen Xiang-Yu Teng Duo-Bing Zhang 《World Journal of Clinical Cases》 SCIE 2024年第7期1251-1259,共9页
BACKGROUND Testicular torsion is the most common acute scrotum worldwide and mainly occurs in children and adolescents.Studies have demonstrated that the duration of symptoms and torsion grade lead to different outcom... BACKGROUND Testicular torsion is the most common acute scrotum worldwide and mainly occurs in children and adolescents.Studies have demonstrated that the duration of symptoms and torsion grade lead to different outcomes in children diagnosed with testicular torsion.AIM To predict the possibility of testicular salvage(TS)in patients with testicular torsion in a tertiary center.METHODS We reviewed the charts of 75 pediatric patients with acute testicular torsion during a 12-year period from November 2011 to July 2023 at the Suzhou Hospital of Anhui Medical University.Univariate and multivariate logistic regression analyses were used to determine independent predictors of testicular torsion.The data included clinical findings,physical examinations,laboratory data,color Doppler ultrasound findings,operating results,age,presenting institution status,and follow-up results.RESULTS Our study included 75 patients.TS was possible in 57.3%of all patients;testicular torsion occurred mostly in winter,and teenagers aged 11-15 years old accounted for 60%.Univariate logistic regression analyses revealed that younger age(P=0.09),body mass index(P=0.004),torsion angle(P=0.013),red blood cell count(P=0.03),neutrophil-to-lymphocyte ratio(P=0.009),and initial presenting institution(P<0.001)were associated with orchiectomy.In multivariate analysis,only the initial presenting institution predicted TS(P<0.05).CONCLUSION The initial presenting institution has a predictive value for predicting TS in patients with testicular torsion.Children with scrotal pain should be admitted to a tertiary hospital as soon as possible. 展开更多
关键词 testicular torsion testicular salvage PEDIATRICS PREDICTORS Case report
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Awareness, Practice and Intention to Practice Testicular Self-Examination among Professional Working Males in Ghana
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作者 Ninon P. Amertil Cecilia Amponsem-Boateng +2 位作者 Elikem K. Ayitey Doris Grace Kpongboe Pamphil Igman 《Journal of Cancer Therapy》 2024年第10期331-345,共15页
Background: The aetiology of Testicular Cancer (TC) is still unknown to researchers but many of the associated risk factors have been identified. These include family history, age, racial origin, cryptorchidism, uroge... Background: The aetiology of Testicular Cancer (TC) is still unknown to researchers but many of the associated risk factors have been identified. These include family history, age, racial origin, cryptorchidism, urogenital malformations, testicular atrophy, and infertility. Given the lack of scientific data on the causes of the disease, it has been asserted in previous studies that the promotion of awareness and early detection are prerequisites to mitigating risks of metastasis as well as improving survival. This study is to assess the awareness, practice, and intention to practice testicular self-examination among professional working males in Accra. Methods: A quantitative cross-sectional design with a structured research instrument was used to collect data from respondants. The purposive and convenience sampling techniques were used to collect data from 300 men at Accra in Ghana. The study was conducted at two (2) Universities and a Senior High school at Accra in Ghana. The data was then analysed using descriptive statistics, logistic regression, multiple linear regression, and structural equation modeling. Results: From the study findings, 37% of male participants rated their knowledge of testicular self-examination and related symptoms as good, 28% of participants practised testicular self-examination monthly, while 65% of respondents expressed their intention to practice monthly testicular self-examination. The findings from logistic regression demonstrated that level of education, age, and marital status of participants had a significant influence on testicular self-examination. Additionally, the multiple linear regression results revealed knowledge and self-efficacy significantly predict testicular self-examination intention. The path coefficient results from the structural equation model are consistent with results from the regression models. Conclusion: This research is the first to investigate testicular self-examination among men in Ghana. The findings revealed awareness and practice of TSE are low among participants. Therefore, the research findings would improve the expertise of physicians and nurses in providing counsel, intervention, and support for patients at risk of testicular cancer. 展开更多
关键词 testicular Cancer testicular Self-Examination Awareness and Practice Health Promotion Men’s Health
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Laparoscopic Orchidopexy after 4 Weeks of Testicular Traction with Preservation of Blood Supply: A New Concept for the Treatment of Intra-Abdominal Cryptorchidism: Original Article
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作者 Ntsobe Tobie Eric Haijin Liu +5 位作者 Nyanit Bob Dorcas Wei Peng Feng Chen Ndikontar Raymond Kouna Tsala Irene Nadine Qian Liu 《Open Journal of Pediatrics》 2024年第2期205-217,共13页
Background: Testicular atrophy is recurrent after orchidopexy for intra-abdominal cryptorchidism due to damage to vessels. Fowlers-Stephens and Shehata methods proposed staged orchidopexy, but are still associated to ... Background: Testicular atrophy is recurrent after orchidopexy for intra-abdominal cryptorchidism due to damage to vessels. Fowlers-Stephens and Shehata methods proposed staged orchidopexy, but are still associated to a rate of atrophy greater than 10%. Purpose: We set out to present a new technique that preserves testicular vessels. Our study is aimed at investigating testicular vitality after surgery. Patients and Method: We reviewed files of boys who underwent orchidopexy for 2 years in our department. Those who have been operated for intra-abdominal cryptorchidism with the new technique and aged between 6 months and 14 years old were included in our study. We excluded boys who have been operated before 6 months and after 14 years old and those who did not respect their follow-up plane. Ultrasound (US) outcomes were used to measure testicular volumes and blood flow at each postoperative visit. The Sample population was divided into group A and group B representing testes that were followed respectively for 12 and 24 months. Results: 22 boys with 25 testes were included in our study;11 testes in group A and 14 testes in group B. In each group, we noted a significant difference of UDT volumes from the third month after surgery with respective P-values 0.05. There was no statistical difference between UDT and contra lateral testes volumes 12 months after surgery in group A and 24 months in group B with respective P-values of 0.07 and 0.72. All volume differential indexes were Conclusion: This method offers a new perspective in performing safe orchidopexy for intra abdominal undescended testes. 展开更多
关键词 LAPAROSCOPY Staged-Orchidopexy Testicar Traction testicular Atrophy
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Outcomes of surgical correction of Peyronie’s disease with plaque excision and grafting: Comparison of testicular tunica vaginalis graft versus bovine pericardium graft
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作者 Ali Eslahi Faisal Ahmed +5 位作者 Mohammad Reza Askarpour Hossein-Ali Nikbakht Iman Shamohammadi Payam Ghasemi Hanieh Alimardani Bahareh Ebrahimi 《Asian Journal of Urology》 CSCD 2024年第3期497-503,共7页
Objective:Peyronie’s disease(PD)is an abnormal wound healing in the penile tunica albuginea.After fibrotic plaque excision,different graft materials have been used to repair the defects,but the optimal graft remains ... Objective:Peyronie’s disease(PD)is an abnormal wound healing in the penile tunica albuginea.After fibrotic plaque excision,different graft materials have been used to repair the defects,but the optimal graft remains unknown.This study aimed to compare the functional outcomes of testicular tunica vaginalis grafts and bovine pericardium grafts in patients with severe PD.Methods:A retrospective comparative study was conducted on 33 PD patients undergoing partial plaque excision and grafting from September 2015 to May 2021.The patients were divided into two groups depending on the type of graft used.For 15 patients in Group B,testicular tunica vaginalis grafts were used to repair the defect,while for 18 patients in Group A,bovine pericardium grafts were used.Data of the patient’s age,comorbidities,sexual function,penile curvature,postoperative complications,need for further treatment,change in penile length,and satisfaction were gathered and compared between the groups.Sexual function was evaluated using the 5-item version of the International Index of Erectile Function(IIEF-5),and a functional less than 20-degree penile curvature after surgery was considered a successful intervention.Results:There was no difference in age,comorbidities,degree of curvature,perioperative IIEF-5,operative time,plaque size,or complication rates.After surgery,a statistically significant improvement in curvature degree(p<0.05)and satisfactory penile appearance(p<0.05)were seen in both groups without any superiority between the two groups(p=0.423 and p=0.840,respectively).With a 30-month follow-up,the IIEF-5 was consistent in both groups,with no statistical significance between the groups(p=0.492).The main change in penile length during the operation was increased and still positive in the last follow-up in both groups without statistical significance(p=0.255 and p=0.101,respectively).Conclusion:Partial plaque excision and corporoplasty with both testicular tunica vaginalis or bovine pericardium grafts are equally effective in treating males with clinically significant PD. 展开更多
关键词 Peyronie's disease Plaque excision testicular tunica vaginalis graft Bovine pericardium graft
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Robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancer
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作者 George McClintock Ahmed S.Goolam +6 位作者 Don Perera Ryan Downey Scott Leslie Peter Grimison Henry Woo Peter Ferguson Nariman Ahmadi 《Asian Journal of Urology》 CSCD 2024年第1期121-127,共7页
Objective:To evaluate the perioperative as well as early oncological outcomes of patients undergoing robotic retroperitoneal lymph node dissection for treatment of testicular cancer.Methods:We conducted a prospective ... Objective:To evaluate the perioperative as well as early oncological outcomes of patients undergoing robotic retroperitoneal lymph node dissection for treatment of testicular cancer.Methods:We conducted a prospective consecutive case series of patients undergoing robotic assisted retroperitoneal lymph node dissection for metastatic testicular cancer between May 2018 and July 2021 at our institution.Data were collected on patient and tumour characteristics,intraoperative and postoperative parameters,and functional and oncological outcomes.Descriptive statistics are presented.Results:Nineteen patients were identified;18(94.7%)completed the procedure robotically and one was converted to open surgery;78.9%of patients had stage≥IIB and 12(63.2%)patients had undergone prior chemotherapy.The median operative time was 300(interquartile range[IQR]240-315)min.Median blood loss was 100(IQR 50-175)mL.Median length of stay was 2(range 1-11)days.All robotically completed patients commenced diet and passed flatus on Day 1 and were discharged by Day 3.The median lymph node yield was 40.5(IQR 38-51)nodes.All patients undergoing nerve-sparing procedures recovered antegrade ejaculatory function.One patient had a Clavien-Dindo III complication(chylous ascites requiring drainage).At a median follow-up of 22.3(IQR 16.3-24.9)months,one patient developed retroperitoneal recurrence,which was successfully treated with second-line chemotherapy;no other patients have had recurrences.Conclusion:Robotic retroperitoneal lymph node dissection is a safe and feasible alternative to open surgery in appropriately selected patients,offering low morbidity.Early oncological outcomes are promising.Larger cohorts and longer follow-ups are required to validate our institution's findings. 展开更多
关键词 Retroperitoneal lymph node dissection Robotic surgery testicular cancer Retroperitoneal node dissection
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Management of Testicular Cancers in Brazzaville
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作者 Roland Bertile Banga-Mouss Yanick Dimi Nyanga +8 位作者 Brice Nkoua Epala Armel Melvin Atipo Ondongo Steve Aristid Ondziel-Opara Eliane Ndounga Alexis Bolenga Louis Constant Mbele Mantsouaka Judith Nsonde Malanda Aanani Séverin Wencesl Odzébé Prosper Alain Bouya 《Open Journal of Urology》 2024年第5期324-332,共9页
Introduction: Testicular cancer accounts for 5% of urological tumors, predominantly affecting young men. The aim of our study was to report the diagnostic and evolutionary aspects of testicular cancer cases treated in... Introduction: Testicular cancer accounts for 5% of urological tumors, predominantly affecting young men. The aim of our study was to report the diagnostic and evolutionary aspects of testicular cancer cases treated in our center. Patients and Methods: A retrospective study conducted over a 15-year period involving 12 patients treated for testicular cancer at the University Hospital of Brazzaville. Results: The median age was 31 years (range 11 to 49 years), with a median consultation delay of 10.6 months (range 3 to 27 months). Scrotal mass was the most common reason for consultation. Cancer was bilateral in two patients. Two patients were admitted with metastatic disease. Histopathological examination favored germ cell tumors in 7 cases, two cases of non-Hodgkin’s malignant lymphoma, and one case of epididymo-testicular adenocarcinoma. Adjuvant chemotherapy resulted in complete remission in patients with germ cell tumors. However, neoadjuvant chemotherapy was not effective in patients admitted with advanced-stage disease. Conclusion: Testicular cancer is a rare condition that is curable in the majority of cases, but its management is often complicated in our setting due to delayed diagnosis caused by taboos surrounding genital organ pathologies. 展开更多
关键词 testicular Cancer Germ Cell Tumor CISPLATIN testicular Lymphoma testicular Adenocarcinoma
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Open Scrotal Trauma Complicated by Testicular Evisceration: An Unusual Injury after a Brawl in 2 Cases
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作者 Atangana Cédric Paterson Savom Eric Patrick +6 位作者 Tim Fabrice Dikongue Diwondi Audrey Ngapanya Youssofa Etobe Cécile Akoa Manga Ismael Fodoung Wamba Danny Bang Guy Aristide 《Open Journal of Urology》 2024年第5期282-289,共8页
Background: Scrotal trauma is a rare injury, and can compromise reproductive function. If in closed trauma, a morphological assessment of the lesion is usually necessary before treatment, in open trauma otherwise, nam... Background: Scrotal trauma is a rare injury, and can compromise reproductive function. If in closed trauma, a morphological assessment of the lesion is usually necessary before treatment, in open trauma otherwise, namely in the case of testicular evisceration, surgical exploration is the rule. Objective: To present the management of open scrotal trauma. Case Presentation: These were two adults aged 42 and 63, admitted for post-traumatic testicular evisceration. One of the patients presented with signs of infection due to a diagnosis delay. Management consisted on surgical exploration, with scrotal debridement and testicular reintegration. The evolution was favourable. Conclusion: Open scrotal trauma is a rare lesion that can cause testicular evisceration. It requires surgical exploration, which should be systematic. 展开更多
关键词 Scrotal Trauma testicular Evisceration INFECTION Surgical Exploration
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Exploring the effect and mechanisms of Epimedium on diabetic testicular injury using network pharmacology,molecular docking,and cell experiments
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作者 Jun-Jun Wei Qiong-Yao Xu +4 位作者 Zhao-Wen Pan Yi-Wei Tu Wei Yu Lan Huang Wen-Liang Zha 《TMR Modern Herbal Medicine》 CAS 2024年第2期19-27,共9页
Background:Studying the potential targets and mechanisms of Epimedium for anti-diabetic testicular injury using network pharmacology,molecular docking,and cell experiments.Methods:Acquisition of major components and t... Background:Studying the potential targets and mechanisms of Epimedium for anti-diabetic testicular injury using network pharmacology,molecular docking,and cell experiments.Methods:Acquisition of major components and targets of Epimedium was based on TCMSP,TCMID,and Symmap databases and retrieval of diabetic testicular injury targets by OMIM,GeneCards,Pharmgkb,and Drugbank databases.Intersecting targets were obtained from the Venny 2.1.0 database and input SRTING data to construct a protein-protein interaction(PPI)network,and key targets were screened in Cytoscape 3.8.0 software.Then the Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)enrichment analyses of intersecting targets were conducted through the DAVID database.Further,AutoDock software was used to verify docking between the main components and the core target proteins.In addition,a Cell Counting Kit-8(CCK-8)assay was used to determine the survival effect of quercetin,the main component of Epimedium,on TM4 sertoli-like cells exposed to palmitic acid(PA).Results:Quercetin,kaempferol and luteolin in epimedium were identified as the main components in the treatment of diabetic testicular injury.It has core target proteins including MMP9,AKT1,and TNF.The biological process mainly involves the regulation of the apoptotic signaling pathway.The key pathways of KEGG are the AGE-RAGE signaling pathway in diabetic complications,PI3K-Akt and MAPK signaling pathway.Molecular docking results showed that quercetin had the strongest binding ability to MMP9.Also,PA-challenged cells had a lower survival rate,which was alleviated by the administration of quercetin.Conclusion:Our findings suggest that Epimedium attenuates diabetes mellitus(DM)-induced testicular injury through AGE-RAGE,PI3K-Akt and MAPK signaling pathway.These insights offer a potential therapeutic strategy for managing DM-induced testicular injury,will be the basis for future clinical research. 展开更多
关键词 EPIMEDIUM diabetic testicular injury network pharmacology molecular docking
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Testicular pain originating from lumbar disc degeneration:A case report 被引量:1
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作者 Xiu-Jie Yan Bing Wu +2 位作者 Xin He Zi-Kai Tian Bao-Gan Peng 《World Journal of Clinical Cases》 SCIE 2023年第8期1794-1798,共5页
BACKGROUND Testicular pain caused by lumbar disease is uncommon in the clinic.Here we reported a case of discogenic low back pain with testicular pain that was successfully cured.CASE SUMMARY A 23-year-old male patien... BACKGROUND Testicular pain caused by lumbar disease is uncommon in the clinic.Here we reported a case of discogenic low back pain with testicular pain that was successfully cured.CASE SUMMARY A 23-year-old male patient presented to our department with chronic low back pain.Based on his clinical symptoms,signs and imaging,he was diagnosed with discogenic low back pain.Since conservative treatment for more than half a year did not significantly improve his low back pain,we decided to treat it with intradiscal methylene blue injection.During the course of surgery,we again identified the low back pain as originating from the degenerated lumbar disc by analgesic discography.Interestingly,the patient’s low back pain disappeared along with the testicular pain that had been present for more than 3 mo.After the operation,the patient’s low back pain improved,and the testicular pain did not reappear.CONCLUSION Intradiscal methylene blue injection is a convenient and effective surgical intervention for the treatment of discogenic low back pain.Lumbar disc degeneration may also be a possible clinical cause of testicular pain.Methylene blue injection in the diseased disc improved the low back pain,and the accom-panying testicular pain was successfully managed. 展开更多
关键词 Disc degeneration testicular pain Low back pain Case report Intradiscal methylene blue injection
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Plantain-based diet modulates atrazine-induced testicular toxicities in rats
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作者 Damilare Emmanuel Rotimi Oluyomi Stephen Adeyemi 《Asian pacific Journal of Reproduction》 2023年第4期170-181,共12页
Objective:To assess the potential of plantain-based diet in modulating testicular toxicities in rats exposed to atrazine.Methods:The plantain-based diet at 50%,25% and 12.5% were prepared from the basal diet by substi... Objective:To assess the potential of plantain-based diet in modulating testicular toxicities in rats exposed to atrazine.Methods:The plantain-based diet at 50%,25% and 12.5% were prepared from the basal diet by substituting the corn starch with plantain fruit pulp flour at different percentages.Wistar rats were fed plantain-based diet in varying concentrations ranging from 12.5% to 50% of the basal diet for 21 days before or after atrazine treatment in a two-phase experiment:preventive and therapeutic phases.The therapeutic model(n=35)had seven groups with 5 rats each,including the control,atrazine,atrazine recovery,atrazine plus plantain-based diet 50%,25%,12.5%,and atrazine plus quercetin groups.The preventive model(n=30)had six groups of 5 rats,consisting of the control,atrazine,50%,25%,12.5% plantain-based diet plus atrazine,and quercetin plus atrazine groups.Gonadal hormones(testosterone,luteinizing hormone and follicle-stimulating hormone),sperm parameters(sperm motility,viability,morphology and concentration),and testicular function indices(protein,cholesterol,glycogen,acid phosphatase,alkaline phosphatase and lactate dehydrogenase)were measured.Results:The gonadal hormones,sperm characteristics,and testicular function indices of the rat testis decreased significantly in the atrazine group alongside degeneration of the histoarchitecture.However,plantain-based diet restored the gonadal hormone concentrations,semen parameters,and testicular function indices in both the preventive and therapeutic models.Conclusions:Treatment with plantain-based diet protects against rat testicular toxicity caused by atrazine via the modulation of gonadal hormones,sperm quality,testicular function index as well as histoarchitecture of rat testes. 展开更多
关键词 PLANTAIN ATRAZINE Endocrine disruptor Environmental toxicants Medicinal biochemistry testicular toxicity
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Pubo-Penile Testicular Ectopia (ETPP) of the Infant of 4 Months about a Case
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作者 Mohamed Lamine Sadou Sacko Balla Keita +4 位作者 Thierno Saidou Barry Mory Sangare Mamadou Madiou Barry Moussa Conde Daniel Agbo-Panzo 《Open Journal of Urology》 2023年第4期108-113,共6页
Pubo-penile testicular ectopia is a rare congenital malformation whose etiopathogenesis remains poorly understood. It represents other testicular ectopias less than 1% of all testicular migration disorders. We report ... Pubo-penile testicular ectopia is a rare congenital malformation whose etiopathogenesis remains poorly understood. It represents other testicular ectopias less than 1% of all testicular migration disorders. We report a clinical observation of a 4-month-old infant who consulted for swelling at the root of the penis associated with vacuity of the right hemi scrotum. An inguinal ultrasound was performed which confirmed the presence of the right testicle. An orchidopexy was performed at 4 months of life by an inguinal approach, the postoperative course was simple with a follow-up of 6 months. 展开更多
关键词 Pubo-Penile testicular Ectopia INFANT Early Orchidopexy
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Testicular mixed germ cell tumor:A case report
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作者 Qi-Fan Xiao Jie Li +1 位作者 Bin Tang Yu-Qing Zhu 《World Journal of Clinical Cases》 SCIE 2023年第28期6902-6907,共6页
BACKGROUND Testicular mixed germ cell tumors(TMGCTs)are rare malignant tumors that are more common in men aged 20–40 years.TMGCTs comprise two or more types of germ cell tumors that primarily affect the testis.Their ... BACKGROUND Testicular mixed germ cell tumors(TMGCTs)are rare malignant tumors that are more common in men aged 20–40 years.TMGCTs comprise two or more types of germ cell tumors that primarily affect the testis.Their onset is undetectable;thus,early diagnosis is challenging.However,early recognition and diagnosis substantially improve patient prognosis.CASE SUMMARY We evaluated a rare case of TMGCT in a male patient presenting with recurrent fever and left supraclavicular lymphadenectasis instead of testicular enlargement and pain,which may easily lead to misdiagnosis.We report the clinical signs and symptoms,histopathological characteristics,and immunohistochemical results of this case of malignant TMGCT.CONCLUSION Our case,which was typical with multiple components,along with a literature review,may serve as a basis for early diagnosis. 展开更多
关键词 Germ cell tumor testicular tumor LYMPHADENECTASIS IMMUNOTHERAPY Case report
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Transcatheter embolization for hemorrhage from aberrant testicular artery after partial nephrectomy:A case report
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作者 Juyoun Youm Min-Jeong Choi +1 位作者 Bong Man Kim Yumi Seo 《World Journal of Clinical Cases》 SCIE 2023年第32期7852-7857,共6页
BACKGROUND Arterial bleeding typically involves the renal artery following partial nephrectomy;in this study,we present a case of bleeding originating from the testicular artery that has not been reported in previous ... BACKGROUND Arterial bleeding typically involves the renal artery following partial nephrectomy;in this study,we present a case of bleeding originating from the testicular artery that has not been reported in previous studies.CASE SUMMARY A 52-year-old man suffered hemorrhage from a perinephric branch of the aberrant left testicular artery after an open nephron-sparing surgery for renal cell carcinoma.Clinical signs of bleeding were manifested by the patient,such as fresh blood drainage from the catheter,decreased hemoglobin levels,and significant vital sign changes.Since computed tomography did not show evidence of active bleeding,transcatheter angiography was conducted to identify the bleeding site.Fluoroscopic spot images confirmed bleeding derived from a perinephric branch of the testicular artery originating from the segmental artery of the left renal artery.Using n-butyl-2-cyanoacrylate,successful transcatheter arterial embolization of the affected branch was performed.Immediately after the embolization procedure,the bleeding ceased,and the patient experienced complete recovery devoid of complications.CONCLUSION In patients with postoperative arterial hemorrhage after partial nephrectomy,the testicular artery can be a rare but notable source of bleeding.Accurate bleeding site localization via angiographic evaluation,followed by transcatheter arterial embolization,can be instrumental for safe,prompt,and effective hemostasis. 展开更多
关键词 Partial nephrectomy HEMORRHAGE testicular artery ANGIOGRAPHY EMBOLIZATION Case report
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大豆异黄酮对坝上长尾鸡生长性能、免疫功能、睾丸发育及血浆生殖激素的影响 被引量:2
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作者 马利芹 官丽辉 利凯 《饲料研究》 CAS 北大核心 2024年第1期34-39,共6页
试验旨在研究大豆异黄酮对坝上长尾鸡生长性能、免疫功能、睾丸发育及生殖激素的影响。选取750只40周龄坝上长尾鸡,随机分为5组,每组3个重复,每个重复50只鸡。Ⅰ组、Ⅱ组、Ⅲ组、Ⅳ组和Ⅴ组饲粮中分别添加5、10、15、20、25 mg/kg大豆... 试验旨在研究大豆异黄酮对坝上长尾鸡生长性能、免疫功能、睾丸发育及生殖激素的影响。选取750只40周龄坝上长尾鸡,随机分为5组,每组3个重复,每个重复50只鸡。Ⅰ组、Ⅱ组、Ⅲ组、Ⅳ组和Ⅴ组饲粮中分别添加5、10、15、20、25 mg/kg大豆异黄酮。预试期7 d,正式试验期63 d。结果显示,Ⅱ组、Ⅲ组、Ⅳ组和Ⅴ组坝上长尾鸡增重显著高于Ⅰ组(P<0.05)。Ⅲ组坝上长尾鸡的胸腺指数显著高于其他组(P<0.05);Ⅲ组坝上长尾鸡的法氏囊指数分别比Ⅰ组、Ⅱ组和Ⅴ组显著提高16.09%、14.70%和22.67%(P<0.05);Ⅲ组坝上长尾鸡的脾脏指数比Ⅰ组显著提高17.98%(P<0.05)。Ⅲ组坝上长尾鸡的睾丸指数最高,显著高于Ⅰ组(P<0.05),提高了11.74%。Ⅲ组坝上长尾鸡的采精量、精子密度和有效精子数显著高于Ⅰ组(P<0.05),分别提高了9.52%、4.79%和8.97%。Ⅲ组坝上长尾鸡的睾酮(TESTO)含量分别比Ⅰ组、Ⅱ组和Ⅴ组显著提高10.42%、4.72%和6.42%(P<0.05);Ⅲ组坝上长尾鸡的黄体生成素(LH)含量分别比Ⅰ组、Ⅱ组和Ⅴ组显著提高7.63%、5.83%和10.12%(P<0.05)。研究表明,大豆异黄酮能够改善坝上长尾鸡的生长性能、免疫功能、睾丸发育、精液品质及血浆生殖激素的分泌水平,且最适添加量为15 mg/kg。 展开更多
关键词 大豆异黄酮 坝上长尾鸡 免疫功能 睾丸发育 血浆生殖激素
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环境温度与睾丸扭转发生的相关性分析研究
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作者 孟庆松 杜家兴 +7 位作者 张明 贾江华 汪鑫 张鹏 马万里 王亚轩 王东彬 齐进春 《中华男科学杂志》 CAS CSCD 2024年第2期128-131,共4页
目的:探讨环境温度是否为睾丸扭转发生的影响因素。方法:收集河北医科大学第二医院2013年12月至2020年12月确诊为睾丸扭转患者的具体临床数据。根据其发病时间在国家气象科学数据中心(http://data.cma.cn/)查询当天当地的气温。将其分为... 目的:探讨环境温度是否为睾丸扭转发生的影响因素。方法:收集河北医科大学第二医院2013年12月至2020年12月确诊为睾丸扭转患者的具体临床数据。根据其发病时间在国家气象科学数据中心(http://data.cma.cn/)查询当天当地的气温。将其分为0℃以下组、0~10℃组、10~20℃组、20℃以上组。根据各个分组睾丸扭转的发生数量,通过相关性分析,获得研究结果。结果:172例睾丸扭转患者中,发生率最高的温度区间是0~10℃组(35.5%)。12.8%的病例发生在0℃以下;34.9%的病例发生在10~20℃;16.9%的病例发生在20℃以上。不同温度区间睾丸扭转的发病率比较,差异有统计学意义(χ^(2)=29.07,P<0.001)。Spearman检验提示不同温度区间与睾丸扭转患病率呈负相关(r=-0.261,P<0.01)。不同季节之间发病率比较差异无统计学意义(χ^(2)=5.349,P>0.05),但睾丸扭转的发病仍主要集中在秋冬季。结论:睾丸扭转的患病率与环境温度之间存在负相关趋势,环境温度降低时,睾丸扭转的患者会相对增加。不同季节之间睾丸扭转发病率无明显差别,但睾丸扭转的发病仍主要集中在秋冬季,提示临床秋冬季时要更加注意睾丸扭转的诊治。 展开更多
关键词 睾丸扭转 环境温度 寒冷 季节 影响因素
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汪受传教授分期论治小儿睾丸鞘膜积液经验
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作者 刘玉玲 陈慧 +1 位作者 方华忠 李琳 《世界中医药》 CAS 北大核心 2024年第7期1015-1018,共4页
睾丸鞘膜积液为小儿常见的泌尿系统疾患。汪受传教授认为本病病位主要在肝,与肺、脾、肾密切相关,主要由水湿不化,湿痰凝聚,留滞肝经,郁结不消所致,治疗当以调理脏腑、利水消肿为基本原则,擅用分期论治。病程初期重在化气利水,病程后期... 睾丸鞘膜积液为小儿常见的泌尿系统疾患。汪受传教授认为本病病位主要在肝,与肺、脾、肾密切相关,主要由水湿不化,湿痰凝聚,留滞肝经,郁结不消所致,治疗当以调理脏腑、利水消肿为基本原则,擅用分期论治。病程初期重在化气利水,病程后期重在培元固本,疏肝理气贯穿始终。临床收效良好,值得推广应用。 展开更多
关键词 睾丸鞘膜积液 分期论治 儿科 名医经验 @汪受传
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补肾中药通过AMPK-mTOR通路提高肾精亏虚大鼠睾丸间质细胞自噬能力
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作者 李朝英 李思睿 +4 位作者 张伟 马昊飞 牛双 段豫磊 牛嗣云 《河北大学学报(自然科学版)》 CAS 北大核心 2024年第6期633-642,共10页
为了探究补肾中药提高肾精亏虚大鼠睾丸间质细胞自噬能力的机制,采用单因素电刺激法建立肾精亏虚大鼠模型,免疫组化及Western blot检测各组睾丸细胞自噬标志蛋白Beclin1、p62、LC3B表达水平以及AMPK和mTOR表达变化.基于肾精亏虚与衰老... 为了探究补肾中药提高肾精亏虚大鼠睾丸间质细胞自噬能力的机制,采用单因素电刺激法建立肾精亏虚大鼠模型,免疫组化及Western blot检测各组睾丸细胞自噬标志蛋白Beclin1、p62、LC3B表达水平以及AMPK和mTOR表达变化.基于肾精亏虚与衰老的密切联系,通过自由基氧化损伤法建立睾丸间质细胞(Leydig细胞)衰老模型,联合AMPK抑制剂,探究何首乌饮激活细胞自噬的分子机制.结果显示:何首乌饮可上调睾丸组织Beclin1蛋白、LC3B表达,下调p62蛋白表达,促进AMPK磷酸化并抑制mTOR激活(P<0.05);细胞实验表明,何首乌饮可通过激活AMPK-mTOR信号通路提高Leydig细胞自噬能力(P<0.05),促进肾精亏虚大鼠睾丸Leydig细胞自噬进程. 展开更多
关键词 何首乌饮 肾精亏虚 睾丸组织 自噬 AMPK-mTOR
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二维超声联合微血管血流成像对睾丸结核的诊断价值
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作者 张秀丽 苏航 +1 位作者 陈争光 韩正阳 《郑州大学学报(医学版)》 CAS 北大核心 2024年第5期715-718,共4页
目的:探讨二维超声联合微血管血流成像(MV-flow)对睾丸结核的诊断价值。方法:选择2023年1月至12月在郑州大学第一附属医院因阴囊疼痛、坠胀,或伴有阴囊肿块就诊,疑似睾丸结核的91例患者为研究对象。均行二维超声检查、彩色多普勒血流显... 目的:探讨二维超声联合微血管血流成像(MV-flow)对睾丸结核的诊断价值。方法:选择2023年1月至12月在郑州大学第一附属医院因阴囊疼痛、坠胀,或伴有阴囊肿块就诊,疑似睾丸结核的91例患者为研究对象。均行二维超声检查、彩色多普勒血流显像(CDFI)和MV-flow。以病理结果为金标准,比较二维超声联合MV-flow及二维超声联合CDFI诊断睾丸结核的效能,同时计算血流像素占比。另外选取20例疑似睾丸结核患者,通过MV-flow获取血管指数(VI),采用同类相关系数(ICC)评估MV-flow检测结果的一致性。结果:91例患者中共有80例病理确诊为睾丸结核。二维超声联合MV-flow诊断睾丸结核的敏感度、特异度、准确度分别为96.3%、54.6%和91.2%,高于二维超声联合CDFI(87.5%、18.2%、79.1%)。MV-flow睾丸内血流像素占比高于CDFI[(2.13±0.81)%vs(1.86±0.70)%,P=0.360]。VI在观察者内和观察者间的一致性良好[ICC(95%CI)分别为0.874(0.683~0.950)、0.945(0.860~0.978)]。结论:相比二维超声联合CDFI,二维超声联合MV-flow对睾丸结核的诊断效能更高。 展开更多
关键词 睾丸结核 超声 彩色多普勒血流显像 微血管血流成像
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层面外科理念下的一种全新的睾丸鞘膜翻转切除术15例经验
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作者 王思成 贾斌 樊体武 《现代泌尿外科杂志》 CAS 2024年第4期359-362,共4页
目的在层面外科的理念下描述一种全新的睾丸鞘膜翻转切除术,改进对睾丸鞘膜积液手术解剖层次的理解并优化手术方式。方法选取2021年1—6月长治医学院附属和平医院泌尿外科收治的15例原发性睾丸鞘膜积液患者,采用经精索内筋膜层面行保留... 目的在层面外科的理念下描述一种全新的睾丸鞘膜翻转切除术,改进对睾丸鞘膜积液手术解剖层次的理解并优化手术方式。方法选取2021年1—6月长治医学院附属和平医院泌尿外科收治的15例原发性睾丸鞘膜积液患者,采用经精索内筋膜层面行保留引带血管的睾丸鞘膜囊翻转切除术进行治疗。收集分析患者的一般资料、手术相关指标、成功率和并发症,并通过术中所见及照片分析术中的解剖学结构及结构间相互关系。结果15例患者均成功完成手术,手术时间为25~48 min,平均(34.0±6.2)min,患者均未出现阴囊血肿或切口感染,术后3个月随访无复发。术中所见解剖学要点如下:精索内筋膜完整包绕睾丸、附睾及精索,该层面是无血管的手术入路;在原发性睾丸鞘膜积液患者中,提睾肌及其筋膜层面是缺如的,与精索外筋膜相邻的是精索内筋膜;术中保留引带有助于睾丸固定于自然位置。结论在精索内筋膜层面行保留引带血管的睾丸鞘膜翻转切除术疗效可靠,层面外科理念下的精准解剖描述有助于提升相关手术技术。 展开更多
关键词 睾丸鞘膜积液 睾丸鞘膜翻转切除术 睾丸 精索内筋膜 层面外科
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卵子透明带保存精子在第二代试管婴儿中的应用研究
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作者 苏占营 张琴 +1 位作者 辜敏 吴成亮 《临床医药实践》 2024年第8期577-581,共5页
目的:探讨利用卵子透明带冷冻保存微量精子在第二代试管婴儿助孕中的应用效果。方法:回顾性分析2019年6月—2023年10月接受睾丸活组织检查取精助孕的40对夫妻,共计65个助孕周期的资料,根据患者助孕周期中精子来源分为A组(40个周期)和B组... 目的:探讨利用卵子透明带冷冻保存微量精子在第二代试管婴儿助孕中的应用效果。方法:回顾性分析2019年6月—2023年10月接受睾丸活组织检查取精助孕的40对夫妻,共计65个助孕周期的资料,根据患者助孕周期中精子来源分为A组(40个周期)和B组(25个周期)。A组采用女性取卵当日男方睾丸穿刺活检精子助孕,B组采用女性取卵当日利用卵子透明带冷冻保存的男性精子助孕(B组患者为上述经历了第一次新鲜睾丸精子助孕后,其中25对夫妻又开展了第2次助孕周期,第2次助孕周期时不再进行睾丸活组织检查取精,而是利用冷冻保存复苏后的精子助孕,共25个周期)。比较两组实验室各项指标[成熟卵母细胞百分率(MII卵率)、2原核胚胎受精百分率(2PN受精率)、2原核卵裂胚胎百分率(2PN卵裂率)、卵裂期优质胚胎百分率(D3优胚率)、囊胚形成率、临床妊娠率],25对接受两次助孕史的夫妻依据前后两次助孕的精子来源,分为新鲜睾丸精子和解冻精子两部分,比较其上述实验室各项指标的差异性。结果:两组MII卵率、2PN受精率、2PN卵裂率、D3优胚率、囊胚形成率、临床妊娠率比较,差异均无统计学意义(P>0.05);另外25对夫妻前后接受两种不同来源精子助孕的指标比较,差异也均无统计学意义(P>0.05)。结论:利用卵子透明带冷冻保存微量精子在无精症患者中能够在保证无新鲜睾丸穿刺精子的情况下得到类似的临床结局,同时可减少男性反复睾丸活组织检查的痛苦及创伤,该方法确保极少量精子在冷冻-复苏过程中不会丢失,此方法容易获取高质量解冻精子。 展开更多
关键词 无精症 卵子透明带 睾丸活组织检查 卵胞浆内单精子显微注射
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