Objective:To explore the effect of nursing intervention based on Caprini risk assessment scale for venous thromboembolism(VTE)in perioperative patients with liver cancer.Methods:A total of 128 hepatocellular cancer(HC...Objective:To explore the effect of nursing intervention based on Caprini risk assessment scale for venous thromboembolism(VTE)in perioperative patients with liver cancer.Methods:A total of 128 hepatocellular cancer(HCC)patients who were hospitalized in our department from January 2021 to March 2022 and met the research criteria were selected.According to odd and even numbers in the order of inclusion,64 cases were divided into two groups:a control group and an observation group.The control group received routine nursing intervention during perioperative period,while the observation group received nursing intervention based on Caprini risk assessment scale for VTE.The incidence of VTE and complications were compared between the two groups.Results:The incidence of VTE and postoperative complications in the observation group were lower than those in the control group(P<0.05).Conclusion:Nursing intervention based on Caprini risk assessment scale for VTE can reduce the incidence of perioperative deep vein thrombosis and complications in patients with liver cancer;thus,it is worthy of clinical application.展开更多
Background The use of nutritional risk screening and assessment is becoming increasingly common in cancer patients.The Nutritional Risk Screening 2002(NRS 2002)is a nutritional risk screening programe with good utilit...Background The use of nutritional risk screening and assessment is becoming increasingly common in cancer patients.The Nutritional Risk Screening 2002(NRS 2002)is a nutritional risk screening programe with good utility.The patient generated-subjective global assessment(PG-SGA)is a method used to assess the nutritional status of cancer patients.The prognostic nutritional index(PNI)and neutrophil to lymphocyte ratio(NLR)are considered to be predictors of the prognosis following treatment for patients with a variety of cancers.However,the relationship between the PNI and NLR in the nutritional screening and assessment in patients with gastric cancer is unknown.Methods A retrospective analysis was performed on 378 patients with gastric cancer who underwent surgery at the First Affiliated Hospital of Guangxi Medical University from August 2019 to December 2020.NRS 2002 and PG-SGA were performed within 24 hours of admission,and indicators such as the serum albumin level,body mass index(BMI),PNI and NLR were measured.Results In the grouping based on the NRS2002,patients in the positive group(NRS 2002≥3)had a higher platelet value,a higher median NLR,and a lower PNI than those in the negative group(NRS 2002<3)(295.50±118.49×10^(9)/L vs.269.36±93.52×10^(9)/L,2.38 vs.1.77,42.36±5.96 vs.46.64±4.29).Based on the PG-SGA grouping,the serum albumin level and lymphocyte count were highest in the mild group(PG-SGA:score 2-3),(36.94±3.51 g/L and 1.91±0.7610^(9)/L)and lowest within the severe group(PG SGA score≥9)(34.09±4.18 g/L and 1.51±0.6410^(9)/L).The BMI was highest in the mild group(23.35±3.00 kg/m^(2))and lowest in the severe group(20.63±2.97 kg/m^(2)),and the PNI was also highest in the mild group(46.50±5.17)and lowest in the severe group(41.64±5.53).However,the NLR was lowest in the mild group(median 1.91)and highest in the severe group(median 2.44).Conclusion The PNI and NLR in gastric cancer patients are closely related to the results of the nutritional risk screening and assessment,suggesting that they may be useful to guide the nutritional interventions for gastric cancer patients.展开更多
Cervical cancer is one of the leading causes of cancer death among females worldwide and its behavior epidemiologically likes a venereal disease of low infectiousness. Early age at first intercourse and multiple sexua...Cervical cancer is one of the leading causes of cancer death among females worldwide and its behavior epidemiologically likes a venereal disease of low infectiousness. Early age at first intercourse and multiple sexual partners have been shown to exert strong effects on risk. The wide differences in the incidence among different countries also influenced by the introduction of screening. Although the general picture remains one of decreasing incidence and mortality, there are signs of an increasing cervical cancer risk probably due to changes in sexual behavior. Smoking and human papillomavirus(HPV) 16/18 are currently important issues in a concept of multifactorial, stepwise carcinogenesis at the cervix uteri. Therefore, society-based preventive and control measures, screening activities and HPV vaccination are recommended. Cervical cancer screening methods have evolved from cell morphology observation to molecular testing. High-risk HPV genotyping and liquid-based cytology are common methods which have been widely recommended and used worldwide. In future, accurate,cheap, fast and easy-to-use methods would be more popular. Artificial intelligence also shows to be promising in cervical cancer screening by integrating image recognition with big data technology. Meanwhile, China has achieved numerous breakthroughs in cervical cancer prevention and control which could be a great demonstration for other developing and resource-limited areas. In conclusion, although cervical cancer threatens female health, it could be the first cancer that would be eliminated by human beings with comprehensive preventive and control strategy.展开更多
This study compared HPV testing and liquid-based cytology (LCT) as performance indicators for cervical cancer screening in a hospital-based study. A total of 61,193 outpatients were screened initially by LCT. Sample...This study compared HPV testing and liquid-based cytology (LCT) as performance indicators for cervical cancer screening in a hospital-based study. A total of 61,193 outpatients were screened initially by LCT. Samples with screening results showing atypical squamous cells of undetermined significance (ASC-US) or worse were referred for colposcopy, and some samples were tested for high-risk HPV types with the Hybrid Capture II system (HC II). Data on LCT (n=61,193) and HC II (n=1056) results were analysed. Overall test positivity for LCT was 2.53% using an ASC-US threshold, 3.11% using a low-grade squamous intraepithelial lesion (LSIL) threshold, and 0.67% using a high-grade squamous intraepithelial lesion (HSIL) threshold. A total of 1839 women (84% of the 3893 patients with abnormal cytology) underwent colposcopy-directed biopsy. HPV was positive in 80.3% of women with cervical intraepithelial neoplasia 1 (CIN1), 88.3% of those with CIN2, 79.2% of women with CIN3 and 50% (2 of 4) of women with invasive cancer. There was a significant increase in the detection of CIN2 or worse with adjunct HPV testing of women with ASC-US and LSIL However, there were detection of CIN2+ cases no differences in the with adjunct HPV testing of women with HSlI.. The results indicate that HPV testing for HSlL triage should not be recommended in cervical cancer screening.展开更多
A significant decrease in the incidence of cervical cancer and mortality is expected when all eligible women have access to regular Screening tests. Factors that can influence participation rate include: acceptability...A significant decrease in the incidence of cervical cancer and mortality is expected when all eligible women have access to regular Screening tests. Factors that can influence participation rate include: acceptability, accessibility, screening interval, promotion of screening among others. This study is aimed at the assessment of the risk factors for cervical cancer, the knowledge and level of utilization of cervical cancer screening among female staff and female undergraduates of Niger Delta University. A standard questionnaire was used for data collection. The questions were made to capture the objectives of the study. 182 (50.6%) were aware of cervical cancer screening, 22 (12.1%) of the respondents have had at least one pap test in the past, the commonest reasons for uptake of screening were;When it is free or subsidized 6 (27.3%), as part of a general screening program 6 (27.3%), Doctor’s request 4 (18.2%) and self-conviction 4 (18.2%). Many 98 (41.4%) of the respondents, considered themselves healthy and did not see any reason to subject themselves to any form of cervical cancer screening. The reasons for uptake and non uptake of cervical cancer screening are statistically significant between the students and staff (x2 = 18.175, p = 0.001;x2 = 11.31, p = 0.046). The mean age for the initiation of penetrative sex among the respondents was 15.4 ± 2.7, 226 (71.1%) had more than one sexual partner and 184 (51.0%) had been treated for sexually transmitted infections in the past. The study shows that awareness of cervical cancer screening and Uptake was low amongst the respondents, this is despite the fact that a large proportion of the respondents had risk factors for cervical cancer.展开更多
Knowledge of cervical cancer and Pap smear screening in a sample population in Makurdi metropolis was assessed using a survey design. Five hundred and seventy-four (574) participants aged 18-60 years, who were accid...Knowledge of cervical cancer and Pap smear screening in a sample population in Makurdi metropolis was assessed using a survey design. Five hundred and seventy-four (574) participants aged 18-60 years, who were accidentally/conveniently sampled in the town, took part in the study. Of this number, 48.3% (N = 277) were males, and 51.7% (N = 297) were females and from diverse occupations. Data were collected using a standardized questionnaire, the knowledge of cervical cancer and Pap Smear Screening Scale (KCPS) with ten items. Results reveal that participants have limited knowledge on cervical cancer and Pap Smear Screening with 35.3% (N = 203) having knowledge, while 64.7% (N = 371 ) having limited knowledge. No statistical significant difference in the knowledge of cervical cancer and Pap Smear Screening between older and younger participants t (553) = -1.69; P 〉 0.05, Single and Married participants t (562) = -0.97; P 〉 0.05, low and high levels of education t (564) = -1.83; P 〉 0.05 was found. Surprisingly, males (mean = 33.55) significantly had more knowledge of cervical cancer and Pap Smear Screening than females (mean = 32.26) t (572) = 2.03; P 〈 0.05 and other participants had better knowledge than health workers t (572) = -2.43; P 〈 0.05. Enlightenment campaigns, Magazines and News papers, Television, Radio, Friends and Schools were some of the sources participants acquired knowledge of cervical cancer and Pap Smear Screening. It is obvious that knowledge of cervical cancer and Pap Smear Screening is limited among the population in Makurdi metropolis, therefore a need to intensify enlightenments and awareness campaigns targeted at all groups of people is imperative.展开更多
Screening for cervical cancer with DNA ploidy assessment by automated quantitative image cytometry has spread throughout China over the past decade and now an estimated 1 million tests per year are done there. Compare...Screening for cervical cancer with DNA ploidy assessment by automated quantitative image cytometry has spread throughout China over the past decade and now an estimated 1 million tests per year are done there. Compared to conventional liquid based cytology, DNA ploidy has competitive accuracy with much higher throughput per technician. DNA ploidy has the enormous advantage that it is an objective technology that can be taught in typically 2 or 3 wk, unlike qualitative cytology, and so it can enable screening in places that lack sufficient qualified cytotechnologists and cytopathologists for conventional cytology. Most papers on experience with application of the technology to cervical cancer screening over the past decade were published in the Chinese language. This review aims to provide a consistent framework for analysis of screening data and to summarize some of the work published from 2005 to the end of 2013. Of particular interest are a few studies comparing DNA ploidy with testing for high risk human papilloma virus(hrH PV) which suggest that DNA ploidy is at least equivalent, easier and less expensive than hrH PV testing. There may also be patient management benefits to combining hr HPV testing with DNA ploidy. Some knowledge gaps are identified and some suggestions are made for future research directions.展开更多
Objective To examine the utility of the Nutrition Risk Screening 2002(NRS 2002),Patient-Generated Subjective Global Assessment(PG-SGA)and serum factors for the preoperative evaluation of gastric cancer patients.Method...Objective To examine the utility of the Nutrition Risk Screening 2002(NRS 2002),Patient-Generated Subjective Global Assessment(PG-SGA)and serum factors for the preoperative evaluation of gastric cancer patients.Methods We examined 181 gastric cancer patients treated at the First Affiliated Hospital of Guangxi Medical University from January 2015 to January 2018.Nutritional assessments were administered within 48 h of admission.The body mass index(BMI)and serum factors were measured,and information on preoperative nutritional support and postoperative complications was recorded.Results Both the NRS 2002 and PG-SGA had positive correlations with age(P<0.05),and negative correlations with albumin,prealbumin,transferrin,hemoglobin,BMI,and bodyweight(P<0.05).The NRS 2002 and PG-SGA scores were positively correlated with each other(r=0.683,P<0.01),but had poor consistency(κ=0.357,P<0.01).During the preoperative period,33.2%of patients received nutritional support,mainly enteral nutrition.The nutritional risk group(NRS 2002≥3)received more support than the group without nutritional risk(NRS 2002<3;P<0.05).Patients with nutritional risk or malnutrition who received preoperative nutritional support had fewer postoperative complications than unsupported patients.The overall rate of complications was 12.2%,and the rate of severe complications(gradeⅢor above)was 5.5%.The malnutrition and nutritional risk groups had higher rates of severe complications.Conclusions The combined application of the NRS 2002,PG-SGA,BMI,and serum nutritional indices was useful for the nutritional screening and assessment of preoperative gastric cancer patients.The NRS 2002 and PG-SGA provided guidance on the need for nutritional support during the preoperative period.展开更多
文摘Objective:To explore the effect of nursing intervention based on Caprini risk assessment scale for venous thromboembolism(VTE)in perioperative patients with liver cancer.Methods:A total of 128 hepatocellular cancer(HCC)patients who were hospitalized in our department from January 2021 to March 2022 and met the research criteria were selected.According to odd and even numbers in the order of inclusion,64 cases were divided into two groups:a control group and an observation group.The control group received routine nursing intervention during perioperative period,while the observation group received nursing intervention based on Caprini risk assessment scale for VTE.The incidence of VTE and complications were compared between the two groups.Results:The incidence of VTE and postoperative complications in the observation group were lower than those in the control group(P<0.05).Conclusion:Nursing intervention based on Caprini risk assessment scale for VTE can reduce the incidence of perioperative deep vein thrombosis and complications in patients with liver cancer;thus,it is worthy of clinical application.
基金supported by the Guangxi Medical and Health Appropriate Technology Development and Promotion Application Project:“Study on the correlation between perioperative nutritional status and vitamin D and C levels and inflammatory factors in patients with gastric cancer”(No.S2021096)“Combined application of biochemical indicators for nutritional therapy in perioperative patients with gastric cancer”(No.S2017018).
文摘Background The use of nutritional risk screening and assessment is becoming increasingly common in cancer patients.The Nutritional Risk Screening 2002(NRS 2002)is a nutritional risk screening programe with good utility.The patient generated-subjective global assessment(PG-SGA)is a method used to assess the nutritional status of cancer patients.The prognostic nutritional index(PNI)and neutrophil to lymphocyte ratio(NLR)are considered to be predictors of the prognosis following treatment for patients with a variety of cancers.However,the relationship between the PNI and NLR in the nutritional screening and assessment in patients with gastric cancer is unknown.Methods A retrospective analysis was performed on 378 patients with gastric cancer who underwent surgery at the First Affiliated Hospital of Guangxi Medical University from August 2019 to December 2020.NRS 2002 and PG-SGA were performed within 24 hours of admission,and indicators such as the serum albumin level,body mass index(BMI),PNI and NLR were measured.Results In the grouping based on the NRS2002,patients in the positive group(NRS 2002≥3)had a higher platelet value,a higher median NLR,and a lower PNI than those in the negative group(NRS 2002<3)(295.50±118.49×10^(9)/L vs.269.36±93.52×10^(9)/L,2.38 vs.1.77,42.36±5.96 vs.46.64±4.29).Based on the PG-SGA grouping,the serum albumin level and lymphocyte count were highest in the mild group(PG-SGA:score 2-3),(36.94±3.51 g/L and 1.91±0.7610^(9)/L)and lowest within the severe group(PG SGA score≥9)(34.09±4.18 g/L and 1.51±0.6410^(9)/L).The BMI was highest in the mild group(23.35±3.00 kg/m^(2))and lowest in the severe group(20.63±2.97 kg/m^(2)),and the PNI was also highest in the mild group(46.50±5.17)and lowest in the severe group(41.64±5.53).However,the NLR was lowest in the mild group(median 1.91)and highest in the severe group(median 2.44).Conclusion The PNI and NLR in gastric cancer patients are closely related to the results of the nutritional risk screening and assessment,suggesting that they may be useful to guide the nutritional interventions for gastric cancer patients.
基金grants from the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (No.2017-I2M-B&R-03 and No.2016-I2M-1-019)。
文摘Cervical cancer is one of the leading causes of cancer death among females worldwide and its behavior epidemiologically likes a venereal disease of low infectiousness. Early age at first intercourse and multiple sexual partners have been shown to exert strong effects on risk. The wide differences in the incidence among different countries also influenced by the introduction of screening. Although the general picture remains one of decreasing incidence and mortality, there are signs of an increasing cervical cancer risk probably due to changes in sexual behavior. Smoking and human papillomavirus(HPV) 16/18 are currently important issues in a concept of multifactorial, stepwise carcinogenesis at the cervix uteri. Therefore, society-based preventive and control measures, screening activities and HPV vaccination are recommended. Cervical cancer screening methods have evolved from cell morphology observation to molecular testing. High-risk HPV genotyping and liquid-based cytology are common methods which have been widely recommended and used worldwide. In future, accurate,cheap, fast and easy-to-use methods would be more popular. Artificial intelligence also shows to be promising in cervical cancer screening by integrating image recognition with big data technology. Meanwhile, China has achieved numerous breakthroughs in cervical cancer prevention and control which could be a great demonstration for other developing and resource-limited areas. In conclusion, although cervical cancer threatens female health, it could be the first cancer that would be eliminated by human beings with comprehensive preventive and control strategy.
基金funded by Beijing Municipal Science & Technology Commission(No.Y0905001000091)
文摘This study compared HPV testing and liquid-based cytology (LCT) as performance indicators for cervical cancer screening in a hospital-based study. A total of 61,193 outpatients were screened initially by LCT. Samples with screening results showing atypical squamous cells of undetermined significance (ASC-US) or worse were referred for colposcopy, and some samples were tested for high-risk HPV types with the Hybrid Capture II system (HC II). Data on LCT (n=61,193) and HC II (n=1056) results were analysed. Overall test positivity for LCT was 2.53% using an ASC-US threshold, 3.11% using a low-grade squamous intraepithelial lesion (LSIL) threshold, and 0.67% using a high-grade squamous intraepithelial lesion (HSIL) threshold. A total of 1839 women (84% of the 3893 patients with abnormal cytology) underwent colposcopy-directed biopsy. HPV was positive in 80.3% of women with cervical intraepithelial neoplasia 1 (CIN1), 88.3% of those with CIN2, 79.2% of women with CIN3 and 50% (2 of 4) of women with invasive cancer. There was a significant increase in the detection of CIN2 or worse with adjunct HPV testing of women with ASC-US and LSIL However, there were detection of CIN2+ cases no differences in the with adjunct HPV testing of women with HSlI.. The results indicate that HPV testing for HSlL triage should not be recommended in cervical cancer screening.
文摘A significant decrease in the incidence of cervical cancer and mortality is expected when all eligible women have access to regular Screening tests. Factors that can influence participation rate include: acceptability, accessibility, screening interval, promotion of screening among others. This study is aimed at the assessment of the risk factors for cervical cancer, the knowledge and level of utilization of cervical cancer screening among female staff and female undergraduates of Niger Delta University. A standard questionnaire was used for data collection. The questions were made to capture the objectives of the study. 182 (50.6%) were aware of cervical cancer screening, 22 (12.1%) of the respondents have had at least one pap test in the past, the commonest reasons for uptake of screening were;When it is free or subsidized 6 (27.3%), as part of a general screening program 6 (27.3%), Doctor’s request 4 (18.2%) and self-conviction 4 (18.2%). Many 98 (41.4%) of the respondents, considered themselves healthy and did not see any reason to subject themselves to any form of cervical cancer screening. The reasons for uptake and non uptake of cervical cancer screening are statistically significant between the students and staff (x2 = 18.175, p = 0.001;x2 = 11.31, p = 0.046). The mean age for the initiation of penetrative sex among the respondents was 15.4 ± 2.7, 226 (71.1%) had more than one sexual partner and 184 (51.0%) had been treated for sexually transmitted infections in the past. The study shows that awareness of cervical cancer screening and Uptake was low amongst the respondents, this is despite the fact that a large proportion of the respondents had risk factors for cervical cancer.
文摘Knowledge of cervical cancer and Pap smear screening in a sample population in Makurdi metropolis was assessed using a survey design. Five hundred and seventy-four (574) participants aged 18-60 years, who were accidentally/conveniently sampled in the town, took part in the study. Of this number, 48.3% (N = 277) were males, and 51.7% (N = 297) were females and from diverse occupations. Data were collected using a standardized questionnaire, the knowledge of cervical cancer and Pap Smear Screening Scale (KCPS) with ten items. Results reveal that participants have limited knowledge on cervical cancer and Pap Smear Screening with 35.3% (N = 203) having knowledge, while 64.7% (N = 371 ) having limited knowledge. No statistical significant difference in the knowledge of cervical cancer and Pap Smear Screening between older and younger participants t (553) = -1.69; P 〉 0.05, Single and Married participants t (562) = -0.97; P 〉 0.05, low and high levels of education t (564) = -1.83; P 〉 0.05 was found. Surprisingly, males (mean = 33.55) significantly had more knowledge of cervical cancer and Pap Smear Screening than females (mean = 32.26) t (572) = 2.03; P 〈 0.05 and other participants had better knowledge than health workers t (572) = -2.43; P 〈 0.05. Enlightenment campaigns, Magazines and News papers, Television, Radio, Friends and Schools were some of the sources participants acquired knowledge of cervical cancer and Pap Smear Screening. It is obvious that knowledge of cervical cancer and Pap Smear Screening is limited among the population in Makurdi metropolis, therefore a need to intensify enlightenments and awareness campaigns targeted at all groups of people is imperative.
文摘Screening for cervical cancer with DNA ploidy assessment by automated quantitative image cytometry has spread throughout China over the past decade and now an estimated 1 million tests per year are done there. Compared to conventional liquid based cytology, DNA ploidy has competitive accuracy with much higher throughput per technician. DNA ploidy has the enormous advantage that it is an objective technology that can be taught in typically 2 or 3 wk, unlike qualitative cytology, and so it can enable screening in places that lack sufficient qualified cytotechnologists and cytopathologists for conventional cytology. Most papers on experience with application of the technology to cervical cancer screening over the past decade were published in the Chinese language. This review aims to provide a consistent framework for analysis of screening data and to summarize some of the work published from 2005 to the end of 2013. Of particular interest are a few studies comparing DNA ploidy with testing for high risk human papilloma virus(hrH PV) which suggest that DNA ploidy is at least equivalent, easier and less expensive than hrH PV testing. There may also be patient management benefits to combining hr HPV testing with DNA ploidy. Some knowledge gaps are identified and some suggestions are made for future research directions.
基金This work was supported by a Medical and Health Suitable Technology Development and Extension Project of Guangxi Province:The combined application of the evaluation and screening of nutritional risk and serum biochemical indexes for nutritional therapy of gastric cancer patients in perioperative period(No.S2017018).
文摘Objective To examine the utility of the Nutrition Risk Screening 2002(NRS 2002),Patient-Generated Subjective Global Assessment(PG-SGA)and serum factors for the preoperative evaluation of gastric cancer patients.Methods We examined 181 gastric cancer patients treated at the First Affiliated Hospital of Guangxi Medical University from January 2015 to January 2018.Nutritional assessments were administered within 48 h of admission.The body mass index(BMI)and serum factors were measured,and information on preoperative nutritional support and postoperative complications was recorded.Results Both the NRS 2002 and PG-SGA had positive correlations with age(P<0.05),and negative correlations with albumin,prealbumin,transferrin,hemoglobin,BMI,and bodyweight(P<0.05).The NRS 2002 and PG-SGA scores were positively correlated with each other(r=0.683,P<0.01),but had poor consistency(κ=0.357,P<0.01).During the preoperative period,33.2%of patients received nutritional support,mainly enteral nutrition.The nutritional risk group(NRS 2002≥3)received more support than the group without nutritional risk(NRS 2002<3;P<0.05).Patients with nutritional risk or malnutrition who received preoperative nutritional support had fewer postoperative complications than unsupported patients.The overall rate of complications was 12.2%,and the rate of severe complications(gradeⅢor above)was 5.5%.The malnutrition and nutritional risk groups had higher rates of severe complications.Conclusions The combined application of the NRS 2002,PG-SGA,BMI,and serum nutritional indices was useful for the nutritional screening and assessment of preoperative gastric cancer patients.The NRS 2002 and PG-SGA provided guidance on the need for nutritional support during the preoperative period.