Longitudinal changes in body weight of breastfeeding mothers in the first year after delivery and its relationship with human milk composition:a combined longitudinal and cross-sectional cohort study

Objective:Postpartum weight retention(PPWR)is a common problem among women after childbirth.The main objectives of this study are to understand the changes in body weight of breastfeeding mothers during long-term follow-up and preliminarily explore the relationship between maternal body weight and human milk composition,including macronutrients,leptin,and adiponectin.Methods:The study included a longitudinal cohort(122 mothers),and a cross-sectional cohort(37 mothers).The human milk,maternal weight,and dietary surveys were collected in the longitudinal cohort at different follow-up time points(1-14 days postpartum,2-4 months postpartum,5-7 months postpartum,and 12-17 months postpartum).The maternal body weight was analyzed using the responses in the survey questionnaires.A milk analyzer based on the mid-infrared spectroscopy(MIRS)was used to determine milk composition,and nutrition analysis software evaluated dietary intakes.In the cross-sectional cohort,participating mothers were asked to provide blood and human milk samples and pertinent information related to maternal body composition.Maternal body composition was measured by bioelectrical impedance analysis(BIA),while ELISA analyzed leptin and adiponectin in milk and serum.Results:At 5-7 months postpartum,the PPWR of breastfeeding mothers was(2.46±3.59)kg.At 12-17 months postpartum,the PPWR was(0.98±4.06)kg.PPWR was found to be negatively correlated with milk fat content within 14 days postpartum and positively correlated at 2-4 months postpartum.In addition,the maternal weight and body muscle mass were positively correlated with leptin and adiponectin in milk.Plasma leptin was positively correlated with the mother’s body weight,body mass index(BMI),FAT percentage,and body fat mass,while plasma adiponectin did not correlate with any parameter.The results also indicate that the PPWR did not correlate with leptin and adiponectin in plasma or milk.Conclusions:Breastfeeding mothers may retain considerable weight gain one year after delivery.Human milk composition may be related to changes in maternal body weight.Leptin and adiponectin in breast milk and leptin in plasma are associated with the maternal body composition.This study supports the notion that maternal nutritional status may affect offspring health through lactation,and future research should focus on exploring weight management of postpartum mothers.

Changing Characteristics of Comfort Index of Human Body in Bengbu City in the Past 40 Years under the Background of Climate Change

Based on the daily meteorological data of Bengbu City during 1981-2020,the changing characteristics of three elements needed for the calculation of the comfort index of human body(CIHB)were discussed,and daily CIHB was classified and discussed.The results show that from 1981 to 2020,annual average temperature tended to increase significantly.Annual average wind speed and relative humidity showed a decreasing trend before 2011 but an increasing trend after 2011.The duration of the four seasons in Bengbu City mainly rose in spring,reduced in winter,declined first and then increased in summer,and rose first and then decreased in autumn.As CIHB was at grades 1 and 9(the most uncomfortable),the three factors had different effects on them.For cold weather,the influence of relative humidity and wind speed on CIHB can not be ignored besides temperature.In hot weather,the influence of temperature was dominant,and the change of annual average temperature could well correspond to the change in the number of very hot days.In the context of climate warming,the number of cold days tended to decline generally,but it was larger in the years with fewer very cold days.Under the background of climate warming,there was no obvious change in the number of days of the overall comfort of human body.The number of hot days was closely related to the duration of summer,and the number of days of grade 8 rose significantly in the years with an increase in the duration of summer.

The levels of osteopontin in human milk of Chinese mothers and its associations with maternal body composition

Objective:This study explored the content and change trend of osteopontin(OPN)in breast milk and analyzed the relationship between OPN in breast milk and maternal body composition.Methods:Breast-feeding mothers were recruited in Xinhua Hospital to collect breast milk and provide pertinent information.The content of OPN in breast milk was determined by enzyme-linked immunosorbent assay(ELISA).Determination of protein content in human milk was performed via the BCA method.The maternal body composition was determined by the bioelectrical impedance method.Serum glucocorticoid receptorα,adiponectin,insulin,and leptin were determined by ELISA.SPSS 25 was used for statistical analysis.Results:In the longitudinal cohort,106 mothers provided 318 milk samples at different lactation periods.The results indicate that the OPN showed dynamic changes.OPN levels were(343.2±163.5)mg/L during 1-14 days postpartum,(228.4±121.5)mg/L during 2-4 months postpartum,and(204.8±100.6)mg/L during 5-7 months postpartum.The content of OPN was very high in the first 1-14 days postpartum and then decreased.Compared with early postpartum milk,the OPN content of mature milk showed a significant relationship with maternal weight-related parameters.Additional body composition analysis was performed in 88 women at the mature milk phase.The results show that the OPN in milk is related to the mother’s body composition,especially the content of skeletal muscle mass,but not to relevant humoral factors.Conclusions:The levels of OPN in human milk of Chinese mothers showed dynamic changes with the extension of lactation time.The OPN in human milk was related to the mother’s body composition but not related to related humoral factors.

The two-way feedback and passing-way of human body

Two-way feedback of human body was published in 1992. The sensation of two-way feedback of body is a special system of human reaction, which maintains and regulates symmetry and balance of human body. The human two-way feedback reacts to human health. For human overall health and delay decrepitude, it is necessary to pay attention to the stimulations (passive acceptance and initiative interventions) and relevant influences in human body and the stimulative effect. In this paper, the experimental research of stimulation and an example of two-way feedback in human body are given. And lay a foundation of prevention, medical treatment and hygiene of human overall health.

Quantum theory-based physical model of the human body in TCM

In the study,a quantum resonant cavity model based on wave-particle duality was proposed for the explanation of the dynamic processes of essence,vigor,and spirit in the human body in traditional Chinese medicine(TCM).It is assumed that there is a macro human order parameter(wave function),and its dynamics are governed by a macro potential field reflecting influences from heaven,earth,and society,and satisfy the generalized Schrodinger equation.This proposed model was applied in the study to interpret basic concepts of human body in TCM,with an aim to unfold the TCM development in the future.

Curved Spine:The Shape of Spine in Taoist Body Diagrams and Its Influence on Medical Body Diagrams

From the early Taoist diagrams of the human body to the end of the Qing dynasty and the beginning of the Republic of China,Taoists exaggerated and deformed the human spine in a shape-shifting manner.It is likely that medical practitioners were influenced by this style of representation,and there are also numerous diagrams of the human body with the curved spine in the lateral-view diagrams of viscera and Ming Tang Tu(明堂图Acupuncture and Moxibustion Chart),which constantly show the human torso in an elliptical“egg shape”.No later than the Ming dynasty,medical practitioners began to depict the actual physiological spinal curve of the human body.By the Qing dynasty,the depiction of the spinal curve in medical diagrams of the human figure showed a tendency to part ways with the Taoist freehand style of the previous generation.Although the representation of the curve of the spine was very crude,later medical images of the human body at least gradually straightened the spine and no longer depicted it in a shape-shifting manner.However,the curved spine in Taoist diagrams of the human body continued to exist,and the presentation of the curved spine never changed.This way of depicting its appearance,which is very different from reality,is shaped by Taoism's special way of perceiving and viewing the body,and may also contain another form of truth.

From the Subjectivity of Human Rights to the Universality of Human Rights——A Preliminary Interpretation of the Theory on the Subjectivity of Human Rights

Universality is one of the essential characteristics of human rights, but there is a substantive difference between idealism and realism in understanding the concept of universality of human rights. The concepts of radical universality and strong universality based on the concept of natural human rights are too idealistic and thus have a high risk of being alienated into a tool of international re-pression in practice. On the contrary, the theory on the subjectivity of human rights can effectively defuse this risk brought about by radical universality and strong universality. Advocating a transition from the universality of human rights to the subjectivity of human rights not only keeps in line with the actual construction process of international human rights, but can also effectively interpret the practical difficul-ties in the realization process of international human rights. Therefore, it can be used as another alternative theory on human rights beyond the theory of natural human rights.

Molecular cloning and characterization of human age-related NADH oxidase (arNOX) proteins as members of the TM9 superfamily of transmembrane proteins

Age-related NADH oxidase (arNOX = ENOX3) proteins are superoxide-generating cell surface oxidases that increase in activity with age beginning at about 30 y. A soluble and truncated exfoliated form of the activity is present in blood and other body fluids. The activity was purified to apparent homogeneity from human urine and resolved by 2-D gel electrophoresis into a series of 24 to 32 kDa components of low isoelectric point. The purified proteins were resistant both to N-terminal sequencing and trypsin cleavage. Cleavage with pepsin revealed peptides corresponding to the TM9 family of transmembrane proteins. Peptide antisera raised to all five members of the human TM9 family sequentially blocked the arNOX activity of human saliva and sera. The soluble truncated N-terminus of the human homolog TM9SF4 was expressed in bacteria. The recombinant protein was characterized biochemically and exhibited ar-NOX activity. The findings identify five arNOX isoforms each of which correspond to one of the five known TM9 family members. The exfoliated soluble arNOX forms are derived from the 24 to 32 kDa N-termini exposed to the cell’s exterior at the cell surface. Each of the shed forms contain putative functional motifs characteristic of ECTO-NOX (ENOX) proteins despite only minimal sequence identity. Our findings identify arNOX as having functional characteristics of ENOX proteins and the TM9 superfamily of proteins as the genetic origins of the five known arNOX isoforms present in human sera, plasma and other body fluids1.

The scientific hypothesis of an 'energy system' in the human body

This paper proposed the scientific hypothesis that human beings have an 'energy system' inside their body and put forward the necessity to propose the hypothesis.In details,this paper explained the hypothesis from its existence,composition,functions,and possible verifying methods.This paper argues that the human body includes both visible and invisible parts.The former is the material system and the latter is the energetic system.As matter and energy can be converted into each other,it is important to study the human body from the perspective of both the material and energetic systems,which can complement each other.The nature of the energetic system is different from that of the material system.The traditional Chinese medicine (TCM) perspective is based on energy;therefore,extending research on the human energy system may lead to the establishment of a modern TCM research field that is firmly grounded in the principles of TCM.Such a research field might generate novel findings.

Research on Dynamic Model of the Human Body

After summarizing the current situation of the research on human body modeling, a new dynamic model containing 5 equivalent masses has been proposed and the corresponding dynamic equations has been deduced too. By using this new model, more detailed information about the situation of the human body under impact and vibration can be obtained. The new model solves the problem that transmission functions of forces inside the human body can't be deduced by using 3-equivalent-mass model. It will find its usage in many applications.

X-Ray Vision: The Mental Genealogy of the Anatomy of the Interior of the Human Body

Background: The concepts of the Young Person and of an Elderly Person go through an evolutionary diversification during the Human lifecycle and are permeable to diverse biopsychosocial factors involved in the definition of the lifecycle stages. Therefore, assessing this subjectivity in different stages of development and population fringes may be a determinant key factor to assist the implementation of successful disease prevention and health promotion strategies. Aim: The aim of the present study was to discern how Fine Arts’ college students of the Anatomy class mentally represent the inner morphology of the human body of the Young Person and of an Elderly Person. Method: For such, 126 students were asked to draw the interior of the body of a Young Person and of an Elderly Person. In all, 252 drawings were collected and analysed, based on a coding data grid designed for this purpose. Hence, a comparative analysis of these two different vital lifecycle phases was achieved. Results: The results suggest anatomical differences in the pictorial representation of the Young Person and of the Elderly Person, namely in the accentuation of the curvatures of the vertebral column, retrusion of the lower jaw and muscle flaccidity. Conclusions: Although the body schema was the same for all individuals, the body image was singularly depicted and linked to each individual’s history, representing a synthesis of his idiosyncratic perceptions, experiences and particularities.

Sensitivity Numerical Analysis of Human Body Exergy Balance under an Unsteady-State Thermal Environment —Behavioral Adaptation Induced by Undesirable Cold Storage by Building Envelope in Winter

We analyzed the relationships between the human body exergy balance and behavioral adaptations induced by undesirable cold storage by a building envelope under an unsteady-state thermal environment in winter. The complex interaction of the warm exergy production by shivering, lifting of the shell ratio, and reduction of the blood flow rate was considered to constitute the physiological adaptation necessary for maintaining the constant core temperature, which was an important aspect in living organisms. In the case of intermittent use room, it was suggested that better thermal comfort and desirable behavioral adaptations, which decreased the consumption of fossil fuels, could be achieved if interior wooden cladding was used in constructions with building envelopes that had a comparatively large heat capacity, or in cases of wooden constructions in which the building envelope heat capacity was comparatively small.

Mapping What They Know: Concept Maps as an Effective Tool for Assessing Students’ Systems Thinking

In 2006 anew biology curriculum called “Human Biology: Emphasizing the Role of Homeostasis” was introduced into the Israeli high school system. Complex systems like those that make up the human body have become increasingly important as a focus of high school education. This study examines the effectiveness of the concept map as a assessment tool for students’ systems thinking, a tool that provides researchers with a detailed picture of the systems thinking development taking place within individual students. The content of the students’ concept maps was translated into information about students’ system thinking using the Systems Thinking Hierarchy (STH) model, a model in which system thinking is categorized according to eight hierarchical characteristics or abilities. The goal was to use the maps to characterize Israeli high school students’ understanding of the body’s systemic nature. To do this, we identified the extent to which the students understand three central elements of systems, namely hierarchy, homeostasis, and dynamism, and then analyzed this understanding according to its place within the hierarchical stages of the STH model. The extensive qualitative data analysis of 48 concept maps made by 11th grade biology majors suggest that the strength of the concept map is in its ability to describe the first two levels of system thinking (analysis and synthesis). However, it proved less successful in eliciting evidence of the third and highest level, particularly of students’ understanding of patterns, of homeostasis and their capacity for temporal thinking.

Measuring the Association of Overweight and Obesity with Human Disease and Other Factors in Bangladesh

Overweight and obesity in people are epidemic in North America and internationally. In the United States, the number of overweight children and adolescents has doubled in the last two to three decades, and similar increasing rates are being observed worldwide, including developing countries as Bangladesh where an increase in Westernization of behavioral and dietary lifestyles is evident. Human diseases associated with overweight and obesity are similar in children as in the adult population. The main purpose of this study was to examine the association between overweight and obesity with human disease and other factors in Bangladesh. We have attempted to estimate the relationship between associated variables by using the Pearson Chi-Square test. It also showed how important an individual variable is by itself. The study also employed a statistical technique namely, logistic regression analysis which has been used to find out the association of overweight and obesity with human disease and other factors. We have seen that 16.96% people are overweight and 4.14% people are obese, i.e. 21.1% people are overweight or obese in Bangladesh. From the logistic regression analysis technique among the independent variables type of place of residence, Highest educational level, Wealth index, Current marital status, Ever had vaccination, Had fever in last two weeks, Had cough in last two weeks, Short, rapid breaths, Problem in the chest or blocked or running nose have significant effect on dependent variable BMI classification.

Research of Water Response under the Action of the Infrared Human Body Radiation by Water Conductometric Sensors

Non-equilibrium thermal and biothermal radiation generated by heated solid materials and hematothermal living organisms are studied by water conductometric sensors. Engineering aspects and physical features of developed water conductometric sensors are given. Procedure and measuring technique are described. Our experiments show the anomalous behavior of water conductivity and associated differential parameters under water heating by biological objects compared with traditional heating sources. Water response to human action strongly depends on psychophysiological and psychoemotional state of the person. Moreover the responses to the action by left and right human hands are substantially different and as a rule are specific to the gender. The possible physicochemical mechanisms of such anomalous water behavior are studied. It is suggested that the observed effects are associated with resonant excitation of vibration-rotation energy levels of water under the influence of bioradiation generated by human organism consisting of approximately 70% water. The results obtained have good perspectives for future applications in different fields of human activity.

An Evaluation of the Core Controversies in Contemporary Western Human Rights Theory——A Study Based on the Examination of the Criterion of Fidelity to Practice

The development of theories on human rights with Chinese characteristics and China’s engagement in global human rights governance cannot be separated from attention to contemporary Western human rights theory.The debate between naturalistic and political conceptions of human rights has a long history,but discussions on the basic criteria for evaluating human rights theories have been insufficient.This article,focusing on the criterion of fidelity to practice,attempts to identify the development trajectory and direction of human rights theory.The universal claims of naturalistic human rights perspectives and the human rights catalog they propose have been criticized for deviating from practice.On the other hand,political conceptions of human rights,while emphasizing domestic human rights practices,have been criticized for their occasional nature and perceived loss of criticality.The broad-way practice theory seeks a third way that goes beyond the divide between these two perspectives.On the one hand,the theory itself faces limitations and the need for reshaping,while on the other hand,the traditional singular practice theory is also undergoing self-renewal.It can be said that the“internal critique”of contemporary Western human rights theory is already underway and will continue.

Build Asian Consensus on Human Rights,Promote-Overview of Academic Viewpoints at the Asian Forum on Human Rights 2022

The Asian Forum on Human Rights was held at the Renmin University of China(RUC)from November 26 to 27,2022.With the theme“Environment,Climate Change and Human Rights,”the event consisted of 12 sub-forums.The forum was hosted by RUC and jointly organized by the RUC Law School,RUC School of Global Governance,Human Rights Center of RUC,RUC Asia-Pacific Institute of Law,and RUC Center for Coordination and Innovation of Food Safety Governance.The forum focused on discussing topics related to climate change and the environment and responded to common concerns of the international community.It built an international exchange platform to facilitate Asian scholars to build consensus on human rights.Covering a wide range of topics,the event promoted academic exchange in various fields.Experts and scholars from both home and abroad built an extensive consensus on topics such as climate change,environmental conservation,and human rights protection through open exchanges and in-depth discussions,contributing their ideas and wisdom to improving the common well-being of Asian people.

The International Communication of Chinese Concept of Human Rights in the New Era

The Chinese concept of human rights serves as the core value of China’s path of human rights development,guiding the comprehensive advancement of China’s human rights cause and providing Chinese wisdom for the development of human rights cause worldwide.Throughout the development process of China’s human rights cause in the new era,the international communication of the Chinese concept of human rights has achieved positive results and played an essential role in the international human rights discourse struggle,external exchanges on human rights,and the transformation of international human rights mechanisms.However,it also faces challenges such as the dominance of Western human rights concepts,the marginalization of the Chinese concept of human rights,the incomplete establishment of China’s external discourse system on human rights,and constraints on international communication channels.Therefore,in the new era,it is crucial to address the weaknesses in the international communication of the Chinese concept of human rights,optimize communication channels,and enhance its international influence.

Research on the Relationship between Phonetic Pronunciation and Human Body Physiology under Background Research Perspective

In this paper, we conduct research on the relationship between phonetic pronunciation and the human body physiology under background research perspective. To achieve sound round, deep, and have a glorious, that mainly depends on the resonance cavity resonance, resonance and harmonic sound. But to achieve the effect of the echo sound with breath intensity of use whether appropriate, laryngeal muscles, the soft palate, tongue muscle coordination. To spit the consonants spray, clearly, depends on stable condition in the throat, your breath muscles in gas and completed, must combine consonants and vowels in training to achieve the purpose of practice, to achieve the effect of the ＂clear pronunciation and mellow voice＂ . More importantly, we integrate background research perspective to optimize the proposed approach that will be meaningful.

The Protection of Human Rights in the Construction of Barrier-free Environment--Viewed from the perspective of the Marxist Human Rights Concept

The construction of a barrier-free environment contains a rich connotation of human rights protection,and is closely related to the study of human rights protection in China.With the evolution of the concept of barrier-free design and the expansion of its beneficiary groups,constructing a barrier-free environment has become a basic task that benefits all members of society and meets the public needs of all the people,with its core goal expanding from the protection of the rights of the disabled to the protection of the basic rights and interests of all members of society.Building a barrier-free environment from the perspective of the Marxist human rights concept is conducive to safeguarding the people’s right to subsistence and development,and at the same time,it satisfies their demand for the right to pursue a high-quality and better life and reflects the common vision of everyone in society fully enjoying human rights.promoting the construction of a barrier-free environment in terms of legal protection based on China’s institutional advantages can improve and innovate the country’s legislation on the construction of a barrier-free environment,so as to play an exemplary and guiding role in enhancing the international barrier-free level and enable all people to enjoy the good life created through the drive to build a barrier-free environment.