It’s Time for New Insights into Renovascular Hypertension at the Molecular Level

At the cellular level, reduced kidney perfusion in atherosclerotic renal arthery disease (ARVD), induces hypoxia, activation of the renin-angiotensin-aldosterone system (RAAS) and cytokine activation. Impaired blood flow in the kidneys creates a microenvironment triggering significant cytokine production, contributing to vascular damage and endothelial disfunction. Interactions between cytokines and endothelial, glomerular, and tubular cells often result in increased vessel permeability, and fibrosis, and contribute to the development of chronic kidney disease (CKD). Molecules such as endothelins, prostaglandins, and nitric oxide play a crucial role at the molecular level. The imbalance between vasoconstrictor and vasodilator factors contributes to vascular dysfunction. Oxidative stress and inflammatory processes at the cellular level contribute to endothelial damage and structural changes in blood vessels. Mineralocorticoid receptor antagonists (MRAs) therapy in the context of ARVD holds promise in reducing fibrosis, promoting angiogenesis and enhancing overall outcomes in patients with this pathology. Recent data also indicates the antioxidative, anti-inflammatory, and antifibrotic effects of SGLT2 inhibitors. They reduce oxidative stress caused by hypoxic conditions and enhance renal perfusion, contributing to the preservation of cellular function. Studies employing Blood Oxygen Level-Dependent (BOLD) imaging have identified adaptations to reduced blood flow, volume, and glomerular filtration rate in post-stenotic kidneys that preserve oxygenation in the medulla and cortex during medical therapy. Data from the literature indicate that despite the partial recovery of renal hypoxia and restoration of blood flow after revascularization, inflammatory cytokines and injury biomarkers remain elevated, and the glomerular filtration rate (GFR) does not recover in ARVD. Restoration of vascular patency alone has failed to reverse tubulointerstitial damage and partially explains the limited clinical benefit of renal stenting. Considering these findings, BOLD MR imaging emerges as a technique capable of providing insights into the critical juncture of irreversibility in ARVD. However, further research is needed to monitor renal hypoxia following renal artery stenting and the inflammatory response over an extended period in conjunction with optimal therapy involving MRAs and SGLT2 agonists. The aim of research at the molecular level enables the identification of potential therapeutic modalities targeting specific molecular pathways, opening the door to innovative approaches in treating renovascular hypertension.

Thinking of Countryside Image and New Countryside Planning with the Renovation Planning of Dazhuang Village as a Study Case

With the construction of new socialist countryside as the background, theories of constructing new countryside were discussed in this study, and approaches to construct new socialist countryside with Chinese countryside landscape images were explored.

Revealing the Circadian Rhythm of Taliang Crocodile Newt(Liangshantriton taliangensis) During Breeding Migration Using a Novel Monitoring Technique

Many animals migrate during the breeding season.It is important to study the patterns of breeding migration of wild animals,especially rare and endangered species.However,current data acquisition methods are too coarse and imprecise for investigating the circadian rhythms of migrations in amphibians.Based on the frustrated total reflection image(FTRI),we developed a new device and recorded the precise migration time of an endangered salamander,Liangshantriton taliangensis.During the breeding period,a total of 33 individuals were effectively recorded.Analysis of the data indicated that the circadian rhythm of breeding migration in L.taliangensis was bimodal,and migration mainly occurred from 05:00 to 13:00(81.82%of the total migration records).The average relative activity intensity index(RAI)of breeding migration peaked in the temperature range of 14.0–16.0°C.With increased average relative air humidity,the activity intensity first increased and then decreased,reaching a peak in the humidity range of 91.0%–97.0%.These results demonstrate that our new device is a viable and accurate method for recording the migration time of target species.It is important to reveal the breeding migration pattern of L.taliangensis,which is important for the conservation of this species.Meanwhile,this new device can be used for field monitoring and conservation studies of amphibians,reptiles and other animals.

The Influence of Short Video on City Image Dissemination in the New Media Era——Taking Tik Tok as an Example

With the popularity and rise of Chongqing,Chengdu,Xi’an and other cities on the short video platform,short video is increasingly becoming a new weapon for the construction and dissemination of the city image.Researching on the content,methods and effects of the hottest video APP Tik Tok,this paper adopts research methods of case analysis and text analysis to investigate how short videos promote the spread of urban image,and explore how they can enhance urban image transmission in the new media era in a better way.

The Influence of Consumer Culture on American New Woman and Their Literary Image in the Early 20th Century

By the study of three great American literary works, The Great Gatsby, Tender is the Night and The Age of Innocence, this paper aims to give a holistic interpretation of"New Woman"and their intrinsic relationship with consumer culture in the light of Baudrillard's theories about the consumer society and the consumer culture.

Beautification of Chinese Architectural Images in the New Media Age

From the perspective of communication science,the communication of architectural images in the new media age has an obvious beautifying trend.Due to the differences in politics,economics,and cultural environment between China and western countries,the beautification of architectural images in China is a unique phenomenon.This study classifies the beautification of Chinese architectural images into different types in terms of image communication:audience orientation,time orientation,space orientation,and cultural orientation.By investigating and analyzing relevant cases,this study explores the beautification of Chinese architectural images in the new media age and puts forward thoughts and evaluation,aiming to better comprehend the relationship between beautification and architectural communication.

Images Construction of Soldiers in News Photos of World War II-Take the Example of News of China During the Period from 1942 to 1946

The news photos of News of China are important historical evidence of reflecting the historical reality of anti-fascist war.Content analysis method is used in this article to analyze the soldiers’images constructed in these news photos.From the research we can learn that the News of China presented the image of Chinese soldiers who struggled in trouble at home and abroad,and the image of the Chinese and American soldiers who united together as a whole to fight against the fascist enemy during the World War II.During the war,it inspired people’s hearts and cohesion of social forces,and laid a foundation for the progress of aid to China and the victory of the anti-fascist war.

Eurovet Unveils the New Image of Hong Kong Mode Lingerie 2010 March 30-31, at the Hong Kong Convention and Exhibition Centre

Organized by Eurovet, the world’s leading lingerie and beachwear trade show organizer and supported by Hong

The New Critical Reading of Desert Places

From the perspective of new criticism, this article attempts at a profound study of Robert Frost's Desert Places so as to better understand the value, reveal the meaning and enjoy the charm of this works.

New Genesis of Natural Coke around Magmatic Intrusion at the Shitai Coalmine of Huaibei City, North China

Objective Studies on components of natural coke formed by the intrusion of sills into coals have attracted much attention,not only because the pyrolytic carbon in natural coke are associated with the magmatic events.

The First Congress of New Development on Molecular Imaging Dec 22 to 24,2011,Guangzhou,China

"The First Congress of New Development on Molecular Imaging" will be held in Guangdong Hotel in Guangzhou, Guangdong province, Dec 22 to 24, 2011. This conference is hosted by Ultrasound Medical Branch of Guangdong Medical Association, Ultrasound Medical Branch of Guangzhou Medical Association, is undertaken by

A new software for automated counting of glistenings in intraocular lenses in vivo

AIM:To assess the performance of a bespoke software for automated counting of intraocular lens(IOL)glistenings in slit-lamp images.METHODS:IOL glistenings from slit-lamp-derived digital images were counted manually and automatically by the bespoke software.The images of one randomly selected eye from each of 34 participants were used as a training set to determine the threshold setting that gave the best agreement between manual and automatic grading.A second set of 63 images,selected using randomised stratified sampling from 290 images,were used for software validation.The images were obtained using a previously described protocol.Software-derived automated glistenings counts were compared to manual counts produced by three ophthalmologists.RESULTS:A threshold value of 140 was determined that minimised the total deviation in the number of glistenings for the 34 images in the training set.Using this threshold value,only slight agreement was found between automated software counts and manual expert counts for the validating set of 63 images(κ=0.104,95%CI,0.040-0.168).Ten images(15.9%)had glistenings counts that agreed between the software and manual counting.There were 49 images(77.8%)where the software overestimated the number of glistenings.CONCLUSION:The low levels of agreement show between an initial release of software used to automatically count glistenings in in vivo slit-lamp images and manual counting indicates that this is a non-trivial application.Iterative improvement involving a dialogue between software developers and experienced ophthalmologists is required to optimise agreement.The results suggest that validation of software is necessary for studies involving semi-automatic evaluation of glistenings.

Emergence of lesions outside of the basal ganglia and irreversible damage to the basal ganglia with severeβ-ketothiolase deficiency:A case report

BACKGROUNDβ-ketothiolase deficiency(β-KTD)is an inherited disease,and insufficient attention has been paid to imageology due to its lower morbidity.Therefore,few lesions outside the basal ganglia have been found before,and the persistent pathological changes have rarely been reported.CASE SUMMARY A 10-mo-old Chinese female patient with a free previous medical history but with poor physical and athletic development had received the haemophilus influenzae vaccine and then developed a low fever 2 d prior.She was initially diagnosed with severe brain injury,central respiratory failure,metabolic acidosis complicated with respiratory alkalosis,hyper-IgE,etc.With further examination,a definite diagnosis ofβ-KTD was made.Symptomatic treatment was adopted.Ten days later,the dyspnea was improved evidently and the ventilator was removed,but there were still obvious abnormalities on magnetic resonance imaging(MRI).The lesions mainly invaded the corpus striatum but were not limited to the basal ganglia.Then,the patient’s disease improved and discharged approximately 1 mo later,and the abnormal lesions on MRI had partially improved.However,for about 1 year,the residual irreversible lesions were observed on MRI,the mental and physical development of the patient was obviously regressive,and extra rehabilitation training was needed.CONCLUSION The case highlights the critical importance of one view that the range of lesions in some patients may be more extensive than previously thought in someβ-KTD patients.In addition to biochemical tests,genetic tests and magnetic resonance imaging are not only conducive to quickly diagnosingβ-KTD but also to partially evaluating the short-and long-term outcomes.Moreover,more attention should be paid to the two mutations(c.478 C>G;c.951 C>T)that may be associated with severeβ-KTD.

Campus Design Strategies Based on Spatial Images： A Case Study of Four New Campuses in Chengdu

From 1999, with the rapid expansion of enrollment scale, colleges have experienced fast development and construction of new campuses. However, the urgency of the demand for campus space at that time led to the shortcomings of paying more attention to speed than connotation during the construction of the new campus. Even now the evaluation of new campuses which have been used for nearly twenty years and whether the space of new campuses has played its due role will affect the display of the heritage and temperament of colleges. This paper uses the typical spatial cognitive concept—spatial image to analyse the elements of spatial images on campuses, summarizes the perceptions of teachers and students towards the space of four new campuses in Chengdu through questionnaire survey and analysis, puts forward the principles of campus space design and the strategies of classification design, and intends to take spatial images as the research cut-in point to provide new ideas and suggestions for the design and improvement of campus space from the perspective of users.

Language Analysis of Liaoning Urban Image in Chinese,American,and Canadian News Framework

The research chose the reports about the cities in Liaoning Province,Dalian,Shenyang,and Anshan as the objects of study.These reports came from the three newspapers China Daily,New York Times,and Globe and Mail.This research was based on Frame Work Theory,and used language analysis and case study as the research methods to identify the discourse and organization.The first result is that there is serious stereotyping about the image of Liaoning cities in American and Canadian news.And Chinese news did not cover entire comprehensive topics and was too late to emergency events,so they lost the chance to be an original source of news and the possibility to set the agenda,even lost the discourse power.The second result is that the differences between Chinese reports and American and Canadian reports implied culture differences,the similarities between Canadian and American reports refer to the culture intercommunity.Third,American and Canadian news used multi-framework to make the reports more reliable,but the lack of multi-dimensional reports declined the trustworthiness.

Feature Selection for Image Classification Based on a New Ranking Criterion

In this paper, a feature selection method combining the reliefF and SVM-RFE algorithm is proposed. This algorithm integrates the weight vector from the reliefF into SVM-RFE method. In this method, the reliefF filters out many noisy features in the first stage. Then the new ranking criterion based on SVM-RFE method is applied to obtain the final feature subset. The SVM classifier is used to evaluate the final image classification accuracy. Experimental results show that our proposed relief- SVM-RFE algorithm can achieve significant improvements for feature selection in image classification.

New Edge-Directed Interpolation Based-Lifting DWT and MSPIHT Algorithm for Image Compression

The amount of image data generated in multimedia applications is ever increasing. The image compression plays vital role in multimedia applications. The ultimate aim of image compression is to reduce storage space without degrading image quality. Compression is required whenever the data handled is huge they may be required to sent or transmitted and also stored. The New Edge Directed Interpolation (NEDI)-based lifting Discrete Wavelet Transfrom (DWT) scheme with modified Set Partitioning In Hierarchical Trees (MSPIHT) algorithm is proposed in this paper. The NEDI algorithm gives good visual quality image particularly at edges. The main objective of this paper is to be preserving the edges while performing image compression which is a challenging task. The NEDI with lifting DWT has achieved 99.18% energy level in the low frequency ranges which has 1.07% higher than 5/3 Wavelet decomposition and 0.94% higher than traditional DWT. To implement this NEDI with Lifting DWT along with MSPIHT algorithm which gives higher Peak Signal to Noise Ratio (PSNR) value and minimum Mean Square Error (MSE) and hence better image quality. The experimental results proved that the proposed method gives better PSNR value (39.40 dB for rate 0.9 bpp without arithmetic coding) and minimum MSE value is 7.4.

Media Representation of Space Images of Shanghai Downtown Areas

With the deepening of the globalization,citizens have realized the mega-cities space elements largely through media,instead of all-over contact with real physical environment,and dominance hierarchy of urban functions constructed by all media has represented certain groups’selective transmission of space images.Taking downtown areas of Shanghai City for example,this study explored space images embodied in internet media on the basis of statistical analysis of place name frequency in the media texts.First,by reviewing relevant theories of media languages and city space image,media-based methods for collecting and analyzing space image were reviewed and sorted out,and theoretical bases for the space images embodied by different media were established and compared.Second,in empirical researches,word frequency of place names in economic news texts was calculated in terms of landmark constructions/buildings,roads,rivers,and sections,spatial accumulative calculation was adopted to describe space images of downtown areas in Shanghai.Third,differences and similarities of space images of these downtown areas in economic news reports and citizens’internet posts were further compared.

New Year's greeting and overview of Artificial Intelligence in Medical Imaging in 2021

As editors of Artificial Intelligence in Medical Imaging(AIMI),it is our great pleasure to take this opportunity to wish all of our authors,subscribers,readers,Editorial Board members,independent expert referees,and staff of the Editorial Office a Very Happy New Year.On behalf of the Editorial Team,we would like to express our gratitude to all of the authors who have contributed their valuable manuscripts,our independent referees,and our subscribers and readers for their continuous support,dedication,and encouragement.Together with an excellent of team effort by our Editorial Board members and staff of the Editorial Office,AIMI advanced in 2020 and we look forward to greater achievements in 2021.