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Dendritic spine degeneration:a primary mechanism in the aging process
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作者 Gonzalo Flores Leonardo Aguilar-Hernández +3 位作者 Fernado García-Dolores Humberto Nicolini Andrea Judith Vázquez-Hernández Hiram Tendilla-Beltrán 《Neural Regeneration Research》 SCIE CAS 2025年第6期1696-1698,共3页
Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a w... Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a wide range of factors, spanning from genetic to environmental factors, and even includes the gut microbiome(GM)(Mayer et al., 2022). All these processes coincide at some point in the inflammatory process, oxidative stress, and apoptosis, at different degrees in various organs and systems that constitute a living organism(Mayer et al., 2022;AguilarHernández et al., 2023). 展开更多
关键词 AGING process STRESS
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TLC Identification and Extraction Process of Rubiasin-1-methyl Ether from Yao Medicine Chuanlianzhu
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作者 Jingrong LU Jiangcun WEI +3 位作者 Xiumei MA Bing QING Meiyan QIU Wen ZHONG 《Medicinal Plant》 2024年第3期35-38,共4页
[Objectives]To establish a thin-layer chromatography(TLC)method for the determination of rubiadin-1-methyl ether in Yao Medicine Chuanlianzhu(Damnacanthus giganteus).[Methods]A silica gel G thin-layer plate was adopte... [Objectives]To establish a thin-layer chromatography(TLC)method for the determination of rubiadin-1-methyl ether in Yao Medicine Chuanlianzhu(Damnacanthus giganteus).[Methods]A silica gel G thin-layer plate was adopted for TLC.Petroleum ether(60-90℃)-chloroform-methanol-water(7:15:3:1)was used as the developing solvent and inspected under ultraviolet lamp(365 nm).The content was determined by Inertsil ODS-3 C 18 column(4.60 mm×250 mm,5μm),mobile phase:acetonitrile-0.2%phosphoric acid gradient elution,detection wavelength 277 nm,flow rate 1.0 mL/min,column temperature 30℃,injection volume 10μL.[Results]The spots of 10 Chuanlianzhu samples from different origins showed the same color at the same position as the control,and the spots were clear and specific.The injection volume of rubiadin-1-methyl ether showed a good linear relationship in the range of 2.90-145μg(R=0.9996).The average recovery rate of rubiadin-1-methyl ether in the low,medium and high dose groups of Yao Medicine Chuanlianzhu was 98.72%,and RSD=1.78%.[Conclusions]This method can effectively identify Yao Medicine Chuanlianzhu medicinal materials and accurately determine the content of rubiadin-1-methyl ether in the medicinal materials.It provides a scientific basis for the development and utilization of Yao Medicine Chuanlianzhu medicinal resources. 展开更多
关键词 Chuanlianzhu THIN-LAYER chromatography (TLC) extraction process Rubiadin-1-methyl EtheR Content determination
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Optimization of Extraction Process for Total Flavonoids from Penthorum chinense Pursh and Comparison of Their Contents from Different Parts
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作者 Hongsheng LIU Jiqiang YAO +2 位作者 Xue BAI Jianying KANG Yefei YUAN 《Medicinal Plant》 2024年第2期10-14,共5页
[Objectives]This study was conducted to optimize the extraction process of total flavonoids from Penthorum chinense Pursh and compare their contents from different parts.[Methods]Single factor and orthogonal experimen... [Objectives]This study was conducted to optimize the extraction process of total flavonoids from Penthorum chinense Pursh and compare their contents from different parts.[Methods]Single factor and orthogonal experiments were designed to optimize the extraction process of total flavonoids from P.chinense Pursh with the volume fraction of ethanol,the ratio of material to liquid,heating reflux extraction time and extraction times as factors,and the content of total flavonoids as the index.A verification test was carried out.The optimized extraction process was adopted to compare the contents of total flavonoids from different parts of P.chinense Pursh.[Results]The best extraction process was extracting the powder of P.chinense Pursh for 2.0 h with 20 times of 55%ethanol by reflux twice.Under this condition,the contents of total flavonoids were 3.63%,8.90%,11.28%,and 4.36%from stems,leaves,flowers and whole grass of P.chinense Pursh,respectively.[Conclusions]The process is reasonable,feasible and stable,and can effectively extract total flavonoids from P.chinense Pursh.The contents of total flavonoids from different parts of P.chinense Pursh were quite different,and the value was higher in the leaves and flowers,so the proportions of leaves and flowers should be paid attention to in the industrial processing of P.chinense Pursh. 展开更多
关键词 Penthorum chinense Pursh Total flavonoids Orthogonal experiments extraction process Content determination
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Influence of the Extraction Process on the Characteristics of Romanian Mountain Walnut Oil
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作者 Anne-Gaëlle Gambert Sabina Niţu +6 位作者 Andra Tămaș Maria Laura Fanani Justine Dupré Clara Delepine Ludovic Chaveriat Patrick Martin Lucian Rusnac 《American Journal of Plant Sciences》 CAS 2024年第10期940-967,共28页
The objective of this work is to extract walnut oil using various processes in order to compare the influence on the nature of the components extracted, and thus identify the areas of potential use. We carried out the... The objective of this work is to extract walnut oil using various processes in order to compare the influence on the nature of the components extracted, and thus identify the areas of potential use. We carried out the extractions by mechanical process, thanks to a press in reduced model provided with a worm. We obtained cold extracted oil whose characteristics slightly diverge from extra virgin oil found in shops in Romania, but its composition is similar. We were also able to extract by chemical process using two methods, Folch and Soxhlet. Commercially available table walnut oils are only cold extracted to avoid the presence of solvents. Those are difficult to remove and strongly oxidize the oil. Currently, consumers appreciate walnut oil for its taste and nutritional qualities. In nutrition, this oil is put forward for its composition rich in polyunsaturated fatty acids, which are needed for human body. Food supplements made from walnut oil are available today. For the moment, this is the only use of walnut oil. Indeed, there are some studies on other fields of application, but they remain in the field of research and nothing has yet been commercialized. In this present study, we compared the chemical and physical properties of cold-extracted oil with the solvent extraction of walnut kernel originating from the mountain region of Rumania. The cold extracted oil has a high content of polyunsaturated fatty acids (63%) and monounsaturated fatty acids (30%), a very low level of saturated fatty acid (7%) and no content of linolenic acid. The Soxhlet and Folch methods produced slightly different oils with increased amounts of minor components, which changes their characteristic. Even when solvent-extracted oils do not meet the standard criteria imposed by the Codex Alimentarius, they offer a possible use in the fields of food, cosmetics industries and biomedicine. 展开更多
关键词 Walnut Oil extractION COMPOSITION Romanian Mountain
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Mechanism of Rosae Rugosae Flos flavonoids in the treatment of hyperlipidemia and optimization of extraction process based on network pharmacology
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作者 Yunxiao Xia Aijinxiu Ma +1 位作者 Zihan Hou Xu Zhao 《Journal of Polyphenols》 2024年第2期65-77,共13页
This study aims to identify a natural plant chemical with hypolipidemic effects that can be used to treat high cholesterol without adverse reactions.Through network pharmacology screening,it was found that Rosae Rugos... This study aims to identify a natural plant chemical with hypolipidemic effects that can be used to treat high cholesterol without adverse reactions.Through network pharmacology screening,it was found that Rosae Rugosae Flos(RF)flavonoids had potential therapeutic effects on hyperlipidemia and its mechanism of action was discussed.TCMSP and GeneCards databases were used to obtain active ingredients and disease targets.Venn diagrams were drawn to illustrate the findings.The interaction network diagram was created using Cytoscape 3.8.0 software.The PPI protein network was constructed using String.GO and KEGG enrichment analysis was performed using Metascape.The results revealed 2 active flavonoid ingredients and 60 potential targets in RF.The key targets,including CCL2,PPARG,and PPARA,were found to play a role in multiple pathways such as the AGE-RAGE signaling pathway,lipid and atherosclerosis,and cancer pathway in diabetic complications.The solvent extraction method was optimized for efficient flavonoid extraction based on network pharmacology prediction results.This was achieved through a single factor and orthogonal test,resulting in an optimum process with a reflux time of 1.5 h,a solid-liquid ratio of 1:13 g/mL,and an ethanol concentration of 50%. 展开更多
关键词 Rosae Rugosae Flos FLAVONOIDS extractION process optimization network pharmacology HYPERLIPIDEMIA
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Optimization of extraction process for total flavonoids of Sophorae Flos for the treatment of hyperlipidemia based on network pharmacology and molecular docking
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作者 Jiale Mao Aijinxiu Ma +1 位作者 Lingling Wang Xu Zhao 《Journal of Polyphenols》 2024年第3期117-129,共13页
This study aimed to investigate the mechanism of action of Sophora Flos(SF)in the treatment of hyperlipidemia(HLP)using network pharmacology and molecular docking methods,and to optimize the extraction process of the ... This study aimed to investigate the mechanism of action of Sophora Flos(SF)in the treatment of hyperlipidemia(HLP)using network pharmacology and molecular docking methods,and to optimize the extraction process of the predicted active components.The STRING database was used for protein interaction analysis and PPI network construction via Cytoscape 3.9.1.Pymol was employed for docking and visualization.An extensive review of SF identifi ed 6 active ingredients,297 related objectives,84 disease objectives,and 57 total objectives.After protein interaction and topology analysis,18 core targets were identified.These included 146 gene function entries(P<0.05).Active compounds,mainly flavonoids,can modulate the expression of various proteins such as TNF,IL-6,IL-1β,PPARG,and TGFB1 to achieve therapeutic effects on HLP.The network pharmacology and molecular docking results suggested that the active fl avonoids component in SF may be related to the treatment of hyperlipidemia.Therefore,the orthogonal experiment method was used to optimize the extraction process of total fl avonoid from SF using ethanol refl ux extraction,based on a single factor experiment.The effects of refl ux time,solid-liquid ratio,ethanol concentration,and other factors on the extraction of total fl avonoid from SF were investigated.The optimum process conditions were refl ux time of 1.25 h,solid-liquid ratio of 1:15 g/mL and ethanol concentration of 60%.Using these conditions,the purity of total fl avonoid extracted from SF was 70.33±0.22%. 展开更多
关键词 Sophorae Flos total flavonoid process optimization network pharmacology HYPERLIPIDEMIA
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Extraction Characteristics of Anthocyanins from Preliminarily-processed Products of Purple Sweet Potatoes during the Gelatinization Process 被引量:1
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作者 魏传斌 张萍 《Agricultural Science & Technology》 CAS 2015年第5期1084-1087,共4页
Objective] This study aimed to investigate the method for efficient utilization and development of purple sweet potatoes. [Method] Purple sweet potatoes were dried at two specific temperatures and prepared into prelim... Objective] This study aimed to investigate the method for efficient utilization and development of purple sweet potatoes. [Method] Purple sweet potatoes were dried at two specific temperatures and prepared into preliminarily-processed products for gelatinization simulation to analyze the extraction amount of anthocyanins from gelatinized samples at different gelatinization stages. [Result] During the gelatinization process, the extraction rate of anthocyanins from purple sweet potato samples reached the highest as the temperature rised from 90 ℃ to 95 ℃,and the extraction amount of anthocyanins reached the maximum at 15 min postheat preservation at 95 ℃. Purple sweet potato samples dried at 60 ℃ exhibited larger retention amount, larger maximum extraction amount and higher maximum extraction rate of anthocyanins compared with those dried at 110 ℃. [Conclusion] Drying at low temperatures and appropriately shortening the initial gelatinization stage below 90 ℃ is conducive to the retention and extraction of anthocyanins from purple sweet potatoes. 展开更多
关键词 Purple sweet potatoes ANTHOCYANIN Starch gelatinization extractION
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Evaluation of the intracellular lipid-lowering effect of polyphenols extract from highland barley in HepG2 cells 被引量:3
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作者 Yijun Yao Zhifang Li +2 位作者 Bowen Qin Xingrong Ju Lifeng Wang 《Food Science and Human Wellness》 SCIE CSCD 2024年第1期454-461,共8页
Active ingredients from highland barley have received considerable attention as natural products for developing treatments and dietary supplements against obesity.In practical application,the research of food combinat... Active ingredients from highland barley have received considerable attention as natural products for developing treatments and dietary supplements against obesity.In practical application,the research of food combinations is more significant than a specific food component.This study investigated the lipid-lowering effect of highland barley polyphenols via lipase assay in vitro and HepG2 cells induced by oleic acid(OA).Five indexes,triglyceride(TG),total cholesterol(T-CHO),low density lipoprotein-cholesterol(LDL-C),aspartate aminotransferase(AST),and alanine aminotransferase(ALT),were used to evaluate the lipidlowering effect of highland barley extract.We also preliminary studied the lipid-lowering mechanism by Realtime fluorescent quantitative polymerase chain reaction(q PCR).The results indicated that highland barley extract contains many components with lipid-lowering effects,such as hyperoside and scoparone.In vitro,the lipase assay showed an 18.4%lipase inhibition rate when the additive contents of highland barley extract were 100μg/m L.The intracellular lipid-lowering effect of highland barley extract was examined using 0.25 mmol/L OA-induced HepG2 cells.The results showed that intracellular TG,LDL-C,and T-CHO content decreased by 34.4%,51.2%,and 18.4%,respectively.ALT and AST decreased by 51.6%and 20.7%compared with the untreated hyperlipidemic HepG2 cells.q PCR results showed that highland barley polyphenols could up-regulation the expression of lipid metabolism-related genes such as PPARγand Fabp4. 展开更多
关键词 Highland barley Polyphenols extract Lipid-lowering effect HepG2 cells
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Design and optimization of a greener sinomenine hydrochloride preparation process considering variations among different batches of the medicinal herb 被引量:1
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作者 Dandan Ren Jiale Xie +2 位作者 Tianle Chen Haibin Qu Xingchu Gong 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第7期77-90,共14页
The current methods used to industrially produce sinomenine hydrochloride involve several issues,including high solvent toxicity,long process flow,and low atomic utilization efficiency,and the greenness scores of the ... The current methods used to industrially produce sinomenine hydrochloride involve several issues,including high solvent toxicity,long process flow,and low atomic utilization efficiency,and the greenness scores of the processes are below 65 points.To solve these problems,a new process using anisole as the extractant was proposed.Anisole exhibits high selectivity for sinomenine and can be connected to the subsequent water-washing steps.After alkalization of the medicinal material,heating extraction,water washing,and acidification crystallization were carried out.The process was modeled and optimized.The design space was constructed.The recommended operating ranges for the critical process parameters were 3.0–4.0 h for alkalization time,60.0–80.0℃ for extraction temperature,2.0–3.0(volume ratio)for washing solution amount,and 2.0–2.4 mol·L^(-1) for hydrochloric acid concentration.The new process shows good robustness because different batches of medicinal materials did not greatly impact crystal purity or sinomenine transfer rate.The sinomenine transfer rate was about 20%higher than that of industrial processes.The greenness score increased to 90 points since the novel process proposed in this research solves the problems of long process flow,high solvent toxicity,and poor atomic economy,better aligning with the concept of green chemistry. 展开更多
关键词 Sinomenine hydrochloride process optimization ANISOLE
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Study on the coupling calculation method for the launch dynamics of a self-propelled artillery multibody system considering engraving process 被引量:1
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作者 Shujun Zhang Xiaoting Rui +1 位作者 Hailong Yu Xiaoli Dong 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第9期67-85,共19页
The launch dynamics theory for multibody systems emerges as an innovative and efficacious approach for the study of launch dynamics,capable of addressing the challenges of complex modeling,diminished computational eff... The launch dynamics theory for multibody systems emerges as an innovative and efficacious approach for the study of launch dynamics,capable of addressing the challenges of complex modeling,diminished computational efficiency,and imprecise analyses of system dynamic responses found in the dynamics research of intricate multi-rigid-flexible body systems,such as self-propelled artillery.This advancement aims to enhance the firing accuracy and launch safety of self-propelled artillery.Recognizing the shortfall of overlooking the band engraving process in existing theories,this study introduces a novel coupling calculation methodology for the launch dynamics of a self-propelled artillery multibody system.This method leverages the ABAQUS subroutine interface VUAMP to compute the dynamic response of the projectile and barrel during the launch process of large-caliber self-propelled artillery.Additionally,it examines the changes in projectile resistance and band deformation in relation to projectile motion throughout the band engraving process.Comparative analysis of the computational outcomes with experimental data evidences that the proposed method offers a more precise depiction of the launch process of self-propelled artillery,thereby enhancing the accuracy of launch dynamics calculations for self-propelled artillery. 展开更多
关键词 Self-propelled artillery Engraving process Multibody system dynamics Launch dynamics
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Effects of friction stir processing and nano-hydroxyapatite on the microstructure,hardness,degradation rate and in-vitro bioactivity of WE43 alloy for biomedical applications 被引量:1
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作者 Bo Wu Farazila Yusof +5 位作者 Fuguo Li Huan Miao A.R.Bushroa Mohd Ridha Bin Muhamad Irfan Anjum Badruddin Mahmoud Z.Ibrahim 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第1期209-224,共16页
Nowadays,magnesium alloys are emerging in biomedical implants for their similar properties to natural bones.However,the rapid degradation of magnesium alloys in biological media hinders successful implantation.Refinem... Nowadays,magnesium alloys are emerging in biomedical implants for their similar properties to natural bones.However,the rapid degradation of magnesium alloys in biological media hinders successful implantation.Refinement of microstructure,as well as reinforcement particles can significantly improve the degradation rate.In this work,multi-pass friction stir processing(FSP)was proposed to synthesize WE43/nano-hydroxyapatite(n HA)surface composite,the microstructure,reinforced particle distribution,micro-hardness,corrosion behavior and in-vitro bioactivity were studied.The subsequent FSP passes of WE43 alloy and WE43/n HA composite refined the grain size which was reduced by 94.29%and 95.92%(2.63 and 1.88μm,respectively)compared to base metal after three passes.This resulted in increasing the microhardness by 120%(90.86 HV0.1)and 135%(105.59 HV0.1)for the WE43 and WE43-n HA,respectively.It is found that increasing FSP passes improved the uniform distribution of n HA particles within the composite matrix which led to improved corrosion resistance and less degradation rate.The corrosion rate of the FSPed WE43/n HA composite after three passes was reduced by 38.2%(4.13 mm/year)and the degradation rate was reduced by 69.7%(2.87 mm/y).This is attributed to secondary phase(Mg24Y5and Mg41Nd5)particle fragmentation and redistribution,as well as a homogeneous distribution of n HA.Additionally,the growing Ca-P and Mg(OH)2layer formed on the surface represented a protective layer that reduced the degradation rate.The wettability test revealed a relatively hydrophilic surface with water contact angle of 49.1±2.2°compared to 71.2±2.1°for base metal.Also,biomineralization test showed that apatite layer grew after immersion 7d in simulated body fluid with atomic ratio of Ca/P 1.60 approaching the stoichiometric ratio(1.67)indicating superior bioactivity of FSPed WE43/n HA composite after three passes.These results raise that the grain refinement by FSP and introduction of n HA particles significantly improved the degradation rate and in-vitro bioactivity of WE43 alloy for biomedical applications. 展开更多
关键词 Friction stir processing Magnesium-based composite NANO-HYDROXYAPATITE Corrosion behavior In-vitro bioactivity
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Process development for the direct solvent extraction of nickel and cobalt from nitrate solution:aluminum,cobalt,and nickel separation using Cyanex 272 被引量:7
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作者 Zela T.Ichlas Don C.lbana 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2017年第1期37-46,共10页
A direct solvent extraction(DSX) process for purifying nickel and cobalt from the nitric acid leach solution of nickel laterite ores was conceived and experimentally probed. The proposed process consists of two solv... A direct solvent extraction(DSX) process for purifying nickel and cobalt from the nitric acid leach solution of nickel laterite ores was conceived and experimentally probed. The proposed process consists of two solvent extraction(SX) steps but with only one extractant - bis(2,4,4-trimethylpentyl)phosphinic acid(Cyanex? 272) - used in both steps. The first extraction step involved the removal of aluminum and zinc, whereas the second extraction step involved the separation of cobalt along with manganese from nickel. The experimental results showed essentially quantitative removal of aluminum(〉97%) and zinc(〉99%) in a single extraction stage using 20vol% Cyanex 272 at pH 2.1. Some cobalt(32%) and manganese(55%) were co-extracted but were easily scrubbed out completely from the loaded organic phase using dilute sulfuric acid at pH ≤ 1.38. Cobalt and manganese in the first extraction raffinate were extracted completely in four extraction stages at staggered pH values of 4.0, 4.4, 4.5, and 4.0 in the first, second, third, and fourth stages, respectively, using also 20vol% Cyanex 272. A small amount of nickel(up to 6.6%) was co-extracted but was easily scrubbed out completely with dilute sulfuric acid at pH 2.0. A flow diagram showing the input and output conditions and the metals separated under the deduced optimum conditions is presented. 展开更多
关键词 solvent extraction ALUMINUM COBALT NICKEL nickel laterite ores
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Phase equilibrium data prediction and process optimizationin butadiene extraction process
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作者 Baowei Niu Yanjie Yi +5 位作者 Yuwen Wei Fuzhen Zhang Lili Wang Li Xia Xiaoyan Sun Shuguang Xiang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第7期1-12,共12页
In response to the lack of reliable physical parameters in the process simulation of the butadiene extraction,a large amount of phase equilibrium data were collected in the context of the actual process of butadiene p... In response to the lack of reliable physical parameters in the process simulation of the butadiene extraction,a large amount of phase equilibrium data were collected in the context of the actual process of butadiene production by acetonitrile.The accuracy of five prediction methods,UNIFAC(UNIQUAC Functional-group Activity Coefficients),UNIFAC-LL,UNIFAC-LBY,UNIFAC-DMD and COSMO-RS,applied to the butadiene extraction process was verified using partial phase equilibrium data.The results showed that the UNIFAC-DMD method had the highest accuracy in predicting phase equilibrium data for the missing system.COSMO-RS-predicted multiple systems showed good accuracy,and a large number of missing phase equilibrium data were estimated using the UNIFAC-DMD method and COSMO-RS method.The predicted phase equilibrium data were checked for consistency.The NRTL-RK(non-Random Two Liquid-Redlich-Kwong Equation of State)and UNIQUAC thermodynamic models were used to correlate the phase equilibrium data.Industrial device simulations were used to verify the accuracy of the thermodynamic model applied to the butadiene extraction process.The simulation results showed that the average deviations of the simulated results using the correlated thermodynamic model from the actual values were less than 2%compared to that using the commercial simulation software,Aspen Plus and its database.The average deviation was much smaller than that of the simulations using the Aspen Plus database(>10%),indicating that the obtained phase equilibrium data are highly accurate and reliable.The best phase equilibrium data and thermodynamic model parameters for butadiene extraction are provided.This improves the accuracy and reliability of the design,optimization and control of the process,and provides a basis and guarantee for developing a more environmentally friendly and economical butadiene extraction process. 展开更多
关键词 Butadiene extraction Phase equilibrium data Prediction methods thermodynamic modeling process simulation
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Study on the green extraction of corncob xylan by deep eutectic solvent
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作者 Bingyu Jiao Le Wang +3 位作者 Haitao Gui Zifu Ni Rong Du Yuansen Hu 《Grain & Oil Science and Technology》 CAS 2024年第1期50-59,共10页
Corn as one of the world's major food crops,its by-product corn cob is also rich in resources.However,the unreasonable utilization of corn cob often causes the environmental pollution,waste of resources and other ... Corn as one of the world's major food crops,its by-product corn cob is also rich in resources.However,the unreasonable utilization of corn cob often causes the environmental pollution,waste of resources and other problems.As one of the most abundant polymers in nature,xylan is widely used in food,medicine,materials and other fields.Corn cob is rich in xylan,which is an ideal raw material for extracting xylan.However,the intractable lignin is covalently linked to xylan,which increases the difficulty of xylan extraction.It has been reported that the deep eutectic solvent(DES)could preferentially dissolve lignin in biomass,thereby dissolving the xylan.Then,the xylan in the extract was separated by ethanol precipitation method.The xylan precipitate was obtained after centrifugation,while the supernatant was retained.The components of the supernatant after ethanol precipitation were separated by the rotary evaporator.The ethanol,water and DES were collected for the subsequent extraction of corn cob xylan.In this study,a novel way was provided for the green production of corn cob xylan.The DES was used to extract xylan from corn cob which was used as the raw material.The effects of solid-liquid ratio,reaction time,reaction temperature and water content of DES on the extraction rate of corn cob xylan were investigated by the single factor test.Furthermore,the orthogonal test was designed to optimize the xylan extraction process.The structure of corn cob xylan was analyzed and verified.The results showed that the optimum extraction conditions of corn cob xylan were as follows:the ratio of corn cob to DES was 1:15(g:mL),the extraction time was 3 h,the extraction temperature was 60℃,and the water content of DES was 70%.Under these conditions,the extraction rate of xylan was 16.46%.The extracted corn cob xylan was distinctive triple helix of polysaccharide,which was similar to the structure of commercially available xylan.Xylan was effectively and workably extracted from corn cob by the DES method.This study provided a new approach for high value conversion of corn cob and the clean production of xylan. 展开更多
关键词 CORNCOB Deep eutectic solvent XYLAN process optimization extractION
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Optimization of the Extraction Process of Astaxanthin from Haematococcus pluvialis with Oil Dissolution Method 被引量:2
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作者 Xiaohui LI Ning ZOU +1 位作者 Donghong SUN Jun ZHANG 《Agricultural Biotechnology》 CAS 2015年第6期70-72,共3页
[ Objective ] This study aimed to optimize the extraction process of astaxanthin from Haematococcus pluvialis with oil dissolution method. [ Method ] Small amounts of acetone or ethanol were separately added into soyb... [ Objective ] This study aimed to optimize the extraction process of astaxanthin from Haematococcus pluvialis with oil dissolution method. [ Method ] Small amounts of acetone or ethanol were separately added into soybean oil for astaxanthin extraction. The extraction efficiency of astaxanthin from H. pluvialis with different methods was compared. [ Result] The extraction efficiency of astaxanthin from H. pluvialis with acetone, acetone + soybean oil, ethanol + soybean oil, soybean oil was 20.46, 21.65, 20.85 mg/g and 13.05 mg/g, respectively. According to the results, acetone + soybean oil led to the highest extraction rate, which was approximately twice that of soybean oil and higher than that of acetone. [ Conclusion ] This study laid the foundation for large-scale production of astaxanthin. 展开更多
关键词 Haematococcus pluvialis extraction process optimization ASTAXANTHIN 0il dissolution method
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Terrorism Attack Classification Using Machine Learning: The Effectiveness of Using Textual Features Extracted from GTD Dataset
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作者 Mohammed Abdalsalam Chunlin Li +1 位作者 Abdelghani Dahou Natalia Kryvinska 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第2期1427-1467,共41页
One of the biggest dangers to society today is terrorism, where attacks have become one of the most significantrisks to international peace and national security. Big data, information analysis, and artificial intelli... One of the biggest dangers to society today is terrorism, where attacks have become one of the most significantrisks to international peace and national security. Big data, information analysis, and artificial intelligence (AI) havebecome the basis for making strategic decisions in many sensitive areas, such as fraud detection, risk management,medical diagnosis, and counter-terrorism. However, there is still a need to assess how terrorist attacks are related,initiated, and detected. For this purpose, we propose a novel framework for classifying and predicting terroristattacks. The proposed framework posits that neglected text attributes included in the Global Terrorism Database(GTD) can influence the accuracy of the model’s classification of terrorist attacks, where each part of the datacan provide vital information to enrich the ability of classifier learning. Each data point in a multiclass taxonomyhas one or more tags attached to it, referred as “related tags.” We applied machine learning classifiers to classifyterrorist attack incidents obtained from the GTD. A transformer-based technique called DistilBERT extracts andlearns contextual features from text attributes to acquiremore information from text data. The extracted contextualfeatures are combined with the “key features” of the dataset and used to perform the final classification. Thestudy explored different experimental setups with various classifiers to evaluate the model’s performance. Theexperimental results show that the proposed framework outperforms the latest techniques for classifying terroristattacks with an accuracy of 98.7% using a combined feature set and extreme gradient boosting classifier. 展开更多
关键词 Artificial intelligence machine learning natural language processing data analytic DistilBERT feature extraction terrorism classification GTD dataset
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Cascading multi-segment rupture process of the 2023 Turkish earthquake doublet on a complex fault system revealed by teleseismic P wave back projection method 被引量:1
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作者 Bonan Cao Zengxi Ge 《Earthquake Science》 2024年第2期158-173,共16页
In this study,the vertical components of broadband teleseismic P wave data recorded by China Earthquake Network are used to image the rupture processes of the February 6th,2023 Turkish earthquake doublet via back proj... In this study,the vertical components of broadband teleseismic P wave data recorded by China Earthquake Network are used to image the rupture processes of the February 6th,2023 Turkish earthquake doublet via back projection analysis.Data in two frequency bands(0.5-2 Hz and 1-3 Hz)are used in the imaging processes.The results show that the rupture of the first event extends about 200 km to the northeast and about 150 km to the southwest,lasting~90 s in total.The southwestern rupture is triggered by the northeastern rupture,demonstrating a sequential bidirectional unilateral rupture pattern.The rupture of the second event extends approximately 80 km in both northeast and west directions,lasting~35 s in total and demonstrates a typical bilateral rupture feature.The cascading ruptures on both sides also reflect the occurrence of selective rupture behaviors on bifurcated faults.In addition,we observe super-shear ruptures on certain fault sections with relatively straight fault structures and sparse aftershocks. 展开更多
关键词 2023 Turkish earthquake doublet back projection method cascading segmented rupture process coseismic triggering super-shear ruptures
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Study of the Reservoir Damage during Cyclic Injection and Extraction Process in the Hutubi Gas Storage 被引量:4
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作者 Wang Jianbo Ge Hongkui +4 位作者 Wang Xiaoqiong Liu Tongyuan Liu Dunqing Zhang Yanjun Wu Shan 《Earthquake Research in China》 CSCD 2018年第2期288-300,共13页
During the injection and extraction process in gas storage,cyclic loading stress is applied to the reservoir pore structure,affecting the capacity and service life of gas storage. To study the influence of cyclic inje... During the injection and extraction process in gas storage,cyclic loading stress is applied to the reservoir pore structure,affecting the capacity and service life of gas storage. To study the influence of cyclic injection and extraction on reservoir physical property,a finite-element model of reservoir elastoplastic damage under the effect of pore pressure is established based on elastoplastic mechanics and fatigue-damage mechanics. Considering the mechanical property of the Hutubi reservoir and the injection-extraction mode of gas storage,the finite-element model is used to study the pore pressure and porosity change,fault safety,and ground surface deformation. The results show that the change in pore pressure and porosity,the deformation of the Hutubi fault,as well as the uplift and sink of the grounds surface are controlled by the fatigue damage of the reservoir pore structure during the injection-extraction process. After a 6-year service life, the cumulative deformation of the reservoir pore reaches its limit,causing pore structure collapse and porosity decrease. As a result,storage capacity declines and the ground surface starts to sink. Through this study,the safety of the Hutubi gas storage is evaluated,and some suggestions for field operations are offered. 展开更多
关键词 Gas storage Injected/extracted FATIGUE DAMAGE POROSITY
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Extraction of Total Phenolic Compounds, Flavonoids, Anthocyanins and Tannins from Grape Byproducts by Response Surface Methodology. Influence of Solid-Liquid Ratio, Particle Size, Time, Temperature and Solvent Mixtures on the Optimization Process 被引量:4
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作者 Hiba N. Rajha Nada El Darra +4 位作者 Zeina Hobaika Nadia Boussetta Eugene Vorobiev Richard G. Maroun Nicolas Louka 《Food and Nutrition Sciences》 2014年第4期397-409,共13页
The current work concerns the optimization process of phenolic compounds solid liquid extraction from grape byproducts at high temperatures and short incubation times. The effect of five experimental parameters (solid... The current work concerns the optimization process of phenolic compounds solid liquid extraction from grape byproducts at high temperatures and short incubation times. The effect of five experimental parameters (solidliquid ratio, particle size, time, temperature and solvent mixture) mostly believed to affect the extraction process was undertaken. A first response surface methodology experimental design was used to optimize the solid-liquid ratio and milling time parameters. A second design was used for the optimization of the quantitative and qualitative parameters. The quantitative parameters studied are: total phenolic compounds, flavonoid content, total monomeric anthocyanin composition and tannin concentration. The qualitative parameters analyzed are: antiradical activity and antioxidant capacity. The second design was based on the use of time, temperature and solvent mixture as optimization parameters. The assays were first conducted separately revealing the best experimental conditions for the maximization of each response variable alone. A simultaneous response surface methodology of all the responses taken together was then conducted, showing the optimal extraction conditions to be: 93 minutes at 94?C and in 66% ethanol/water solvent. The maximal response values obtained for each parameter are: Total Phenolic Compounds yield (5.5 g GAE/100g DM), Flavonoid Content (5.4 g GAE/100g DM), Total Monomeric Anthocyanin yield (70.3 mg/100g DM), Tannin Concentration (12.3 g/L), Antiradical Activity (67.3%) and Total Antioxidant Capacity (393 mgAAE/L). All of the optimal values were acquired at 3 mL/g solid-liquid ratio and 6.8 min milling time. The obtained extracts could be used as natural bioactive compounds in several industrial applications. 展开更多
关键词 PHENOLIC Compounds GRAPE BYPRODUCTS extractION Optimization Response Surface Methodology Antioxidant
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Comparative Study on the Different Extraction Processes of Dietary Fiber from Sweet Potato 被引量:4
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作者 QUAN Gui-jing GENG Da-wei 《Chinese Food Science》 2012年第3期5-8,共4页
[Objective] To compare the extraction results of several different methods. [Method] The dietary fiber was extracted from sweet potato respectively by the sieve method, the enzymatic process and enzyme-alkali method. ... [Objective] To compare the extraction results of several different methods. [Method] The dietary fiber was extracted from sweet potato respectively by the sieve method, the enzymatic process and enzyme-alkali method. The extraction results of the three methods were optimized and compared. [Result] The extraction rate of dietary fiber by enzymatic method was the highest, which could reach 38% of total potato residue. The properties of dietary fiber extracted by the three methods were compared, the results indicated that the dietary fiber extracted by enzymatic method had good water-holding capacity, soil absorption and expansion. [Conclusion] The enzymatic method is the best for extracting dietary fiber from sweet potato. 展开更多
关键词 Dietary fiber Sweet potato extraction process CHARACTERISTICS China
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