Pharmacological Investigation on the Qi-Invigorating Action of Schisandrin B: Effects on Mitochondrial ATP Generation in Multiple Tissues and Innate/Adaptive Immunity in Mice

Schisandrae Fructus, containing schisandrin B (Sch B) as its main active component, is recognized in traditional Chinese medicine (TCM) for its Qi-invigorating properties in the five visceral organs. Our laboratory has shown that the Qi-invigorating action of Chinese tonifying herbs is linked to increased mitochondrial ATP generation and an enhancement in mitochondrial glutathione redox status. To explore whether Sch B can exert Qi-invigorating actions across various tissues, we investigated the effects of Sch B treatment on mitochondrial ATP generation and glutathione redox status in multiple mouse tissues ex vivo. In line with TCM theory, which posits that Zheng Qi generation relies on the Qi function of the visceral organs, we also examined Sch B’s impact on natural killer cell activity and antigen-induced splenocyte proliferation, both serving as indirect measures of Zheng Qi. Our findings revealed that Sch B treatment consistently enhanced mitochondrial ATP generation and improved mitochondrial glutathione redox status in mouse tissues. This boost in mitochondrial function was associated with stimulated innate and adaptive immune responses, marked by increased natural killer cell activity and antigen-induced T/B cell proliferation, potentially through the increased generation of Zheng Qi.

Systematic and Theoretical Unfolding of Research on Xi Jinping’s Discourses on Respecting and Protecting Human Rights

Xi Jinping’s discourses on respecting and protect-ing human rights stand as a shining example of the sinicization and modernization of Marxist human rights theory,embodying profound theoretical,political,practical,and cultural logic.Existing research has conducted comprehensive and systematic theoretical analysis and academic extractions on the following contents:the core essence in-herent in these important discourses,including the“theory of human rights concepts,”the“theory of human rights paths,”the“theory of human rights practices,”the“theory of human rights protection,”and the“theory of human rights governance,”along with their profound theoretical significance,practical significance,and global signifi-cance.In the future,researchers should emphasize efforts on studying the original texts and understanding the original principles.While focusing on the precision of concepts,the scientific nature of the prop-ositions,the maturity of theoretical systems,and the rigor of internal logic related to Xi Jinping’s discourses on respecting and protecting human rights,researchers should also pay attention to constructing a discourse system on human rights from the dimensions of discourse power,discourse cluster,and discourse field.Researchers should be adept at drawing innovative insights into human rights theory from China’s vibrant human rights practices and the vast masses of people.This approach will facilitate the systematic unfolding,academic trans-formation,and innovative development of Xi Jinping’s discourses on respecting and protecting human rights.

Assessing the dynamics of human activity intensity and its natural and socioeconomic determinants in Qinghai-Tibet Plateau

Investigating the spatiotemporal variation of human activity intensity and its determinants is a crucial basis for further revealing the mechanism of human-environment interaction and optimizing the human development mode.In this study,the human activity intensity on the Qinghai-Tibet Plateau(QTP)from 1990 to 2020 was measured based on the quantitative model of land use data and the actual regional background,and the under-lying natural and socioeconomic determinants were investigated using spatial econometric methods.The results demonstrate that(1)the human activity intensity in QTP has increased by 11.96%,and there are differences in different spatial scales;the areas with high human activity intensity are distributed in the Hehuang Valley where Xining City and its surrounding areas are located,as well as the One-River and Two-River Area where Lhasa City and surrounding areas are located.(2)Human activity intensity has significant positive spatial spillover,suggesting that local changes will cause changes in the same direction in adjacent areas.(3)The human activ-ity intensity in QTP is affected by various determinants.Concerning socioeconomic factors,the economic level has no significant impact on the human activity intensity in QTP,which differs from the general regional law.Both urbanization and traffic conditions have a significant positive effect,and the impact intensity continues to increase.Concerning natural factors,topographic relief has a significant positive effect;the impacts of temper-ature and vegetation coverage have changed from insignificant to a significant positive effect;the impacts of precipitation and river network density have not been verified;there is no linear relationship between altitude and human activity intensity in the entire QTP,while it exists in local regions.Finally,this study proposes three policy implications for the realization of a more harmonious human-environment relationship in QTP.

Human Rights Connotations and Its Legal Protection in the Harmonious Coexistence between Humans and Nature

Promoting the unity of human nature and sociality in practice is a fundamental path dependence for achieving people's well-rounded development.Within the context of harmonious coexistence between humans and nature,the practice of the unity of human nature and sociality is allowed to be truly implemented,and people's well-rounded development moves from possibility to reality.Strengthening the protection of human rights for people's well-rounded development in the harmonious coexistence between humans and nature not only requires the expansion of the connotations of environmental rights from“the right to a healthy environment”to“the right to a beautiful environment”,but also necessitates the formation of a collaborative framework between environmental rights and development rights.For legal responses to the expansion of the connotations of environmental rights,it is necessary to implement such expansions in environmental legislation,enhance the underlying principles,and make progress in the development of systematic environmental legislation simultaneously.Regarding the legal promotion of the synergy between environmental rights and development rights,it is essential to follow the guidance of the“Two Mountains Theory,”take the coordinated functions of environmental and traditional legal departments as the basis,and build a legal mechanism for the realization of the value of ecological products and services.

An Exploration of Human Nature and a Challenge Against Conventional Morality of American South——On the Theme ofThe Adventures of Huckleberry Finn

文章通过对马克.吐温名著《哈克贝利.芬历险记》主题的分析,深刻探讨了马克.吐温对人的本性的探索和对美国南方传统道德的挑战,并进而提出了与现今社会紧密联系的人文关怀问题。

Marx's Theory of Humanity and Nature

Marx's theory of humanity and nature is an indispensable part of Marx's theory of social development. The history of the development of human society is essentially a natural historical process. Human must start from certain natural premises and start from a combination of certain natural premises and human practices. This is the objective process and inevitable law of the development of human society. Grasping and understanding the scientific connotation of Marx's theory of humanity and nature has very important guiding significance for the development of human society.

On the Ancient Educational Thought under the Opposite View of Human Nature of the Pre-Qin Scholars--On its Value to Contemporary Higher Education

The pre-qin Scholars’views on human nature could be divided into two types:malleable human nature and immalleable human nature.Based on the theory of the malleability of human nature,Confucianism formed an educational concept aiming at shaping the ideal personality of Confucianism.The theory of immutability of human nature has become the root of the two distinct educational concepts of Taoism,which advocates letting nature take its course,and Taoism,which aims at reforming human behavior.Either idea has its reasonableness.All of these have a very important impact on our higher education today.

The Aggro of "Human Nature" and "Divine Nature"

The love is the topic of the abyss of time of mankind, but inhibits in the asceticism of western religion under, the love often takes a tragedy color. In the western literature work depiction concerning the love of clergy, then there is the aggro of "human nature" and "divine nature". This text tries to explain west from three works religion bottom of love tragedy.

Comparison and Inspiration of the Theme of Relationship between Human Beings and Nature in the Field of Literature between China and the West

The relationship between human beings and nature influences the expressions and manifestations of literature. Literature can spy on the nature exploration of human society and ideological values in the thinking and behavior patterns,expressing the relationship between human beings and nature. Through expressions of literature in China and the West,we draw lessons from W estern literary expressions in the developing relationship between man and nature,and get inspiration for the development of Chinese literature.

Retrospect on the Thought of Clean Government in History and Today -- Based on the Doctrine of Evil Human Nature of Syun Zih

In recent years,with the accelerating development of the socialist market economy and the process of globalization,corruption has appeared and become more and more serious,causing serious harm to the interests of the state and people,so the construction of a clean and honest government draws people’s attention.The doctrine of evil human nature of Syun Zih explained profound theories concerning the nature of human beings and the view of interest with simple language,from which the origin of the construction of a clean and honest government could be found.As a result,we can have a right starting point,representing the fundamental interests of the overwhelming majority of people in the long-term exploration.The doctrine of evil human nature of Syun Zih plays an irreplaceable role in the correct understanding and analysis of the construction of a clean and honest government and the construction of the incorrupt government culture.

The Relationship Between Human Being and Nature in The Call of the Wild: A Perspective of Eco-Criticism

The Call of the Wild,one of the most popular novels in the early twentieth-century America,is the first best-selling book of Jack London.As far as this novel is concerned,the main character Buck represents nature.He deals with all kinds of peo⁃ple.The good treat Buck(nature)very well and live harmoniously with him.The evil treat Buck(nature)maliciously,just like fight⁃ing against their enemies.This novel shows the damages people did to nature and the imbalance between human being and nature.The author’s ecological awareness finds its full expression in the novel.The relationship between human and nature in the novel will be analyzed from the perspective of eco-criticism and the ecological theme of the novel will be discussed in a bid to arouse peo⁃ple’s ecological consciousness and environmental protection awareness.

Interpreting the Evil Nature of the Human from Symbolism in The Destruc⁃ tors and Lord of the Flies

War has brought mankind a seething world,and the evil of war has brought western civilization and morality to a dead end.This paper discusses William Golding’s novel Lord of the Flies and Graham Greene’s The Destructors.To have a better under⁃standing of the autho’s thought:war is rooted in the original evil of human nature.In the novel,there is no external binding force,such as ethical,moral,legal and religious control.The original evil of human nature is revealed,and the fierce conflict between civi⁃lization and barbarism is aroused,which are intertwined and manifest themselves through multiple symbolic meanings.Based on the theory of symbolism,the paper will classify the name,objects and characters with symbolic significance that appear in large numbers in two novels,and discuss its symbolic meaning and the function of these symbolic meanings to the development of the theme respectively.In order to better grasp the moral of the novel as a whole,ring the alarm bell for human beings,and cause peo-ple to ponder over the various evils of human beings.

Disinfection Byproducts and Their Precursors in Drinking Water Sources:Origins,Influencing Factors,and Environmental Insights

Tracing the contamination origins in water sources and identifying the impacts of natural and human processes are essential for ecological safety and public health.However,current analysis approaches are not ideal,as they tend to be laborious,time-consuming,or technically difficult.Disinfection byproducts(DBPs)are a family of well-known secondary pollutants formed by the reactions of chemical disinfectants with DBP precursors during water disinfection treatment.Since DBP precursors have various origins(e.g.,natural,domestic,industrial,and agricultural sources),and since the formation of DBPs from different precursors in the presence of specific disinfectants is distinctive,we argue that DBPs and DBP precursors can serve as alternative indicators to assess the contamination in water sources and identify pollution origins.After providing a retrospective of the origins of DBPs and DBP precursors,as well as the specific formation patterns of DBPs from different precursors,this article presents an overview of the impacts of various natural and anthropogenic factors on DBPs and DBP precursors in drinking water sources.In practice,the DBPs(i.e.,their concentration and speciation)originally present in source water and the DBP precursors determined using DBP formation potential tests—in which water samples are dosed with a stoichiometric excess of specific disinfectants in order to maximize DBP formation under certain reaction conditions—can be considered as alternative metrics.When jointly used with other water quality parameters(e.g.,dissolved organic carbon,dissolved organic nitrogen,fluorescence,and molecular weight distribution)and specific contaminants of emerging concern(e.g.,certain pharmaceuticals and personal care products),DBPs and DBP precursors in drinking water sources can provide a more comprehensive picture of water pollution for better managing water resources and ensuring human health.

Investigation of Anthropogenic Activities along the Mamouwol River in the Urban Commune of Mamou (Republic of Guinea)

The monitoring of our watercourses for their preservation must be an imperative concern of the whole population.The aim of this study is to describe the main causes of degradation and destruction of the natural resources of the Mamouwol River in the Mamou commune.Data were collected using a survey method(questionnaire,interviews and observations).The study revealed that extensive agro-pastoral activities are the main socio-economic activity of the population,accounting for 78.5%-90%and 20.30%respectively.Fishing follows(1.2%).Related activities include handicrafts and petty trade;Other human activities:hunting(11%),charcoal burning(58%),brick making and firing(45.6%).Riverbanks and water resources in the vicinity of dwellings are damaged and polluted by socio-economic activities and the use of agricultural inputs.The absence of industrial units on the path for the data collection.

The Religious and Humane Significance of the Death of Two Heroes in Scarlet Letter

Most of Nathaniel Hawthorne's masterpieces are created with the theme of morality,and are used to analysis and reveal"good and evil human nature"through the methods of profound symbolism and delicate psychological description. To reemerge the spirit of The Scarlet Letter,Which is considered as Hawthorne's religious view and humanistic feeling,the death of two heroes in this novel should be analyzed in the aspects of religion and human nature,and even in the aspects of the vocabulary,theme and mental world of main characters.

Human Nature: A Reflection of “The Minister’s Black Veil: A Parable”

According to Hawthorne’s "The Minister’s Black Veil: A Parable", we can know that the author thinks human nature is evil. This paper discusses the following questions: what is human nature? Whether human nature exists? And how to realize human nature?

Exploring Green Development From the Perspective of Sociology:Logical Basis,Constraints,and Optimization Paths

With the advancement of ecological conservation in China,the concept of green development has gained extensive acceptance and recognition.Exploring green development from the perspectives of environmental protection and sociology holds great theoretical value and practical significance in studying the issues related to green development.Firstly,this paper examines green development in light of the objective needs of the economic and social transformation in the international community and China,and deconstructed its underlying social logic.Secondly,it further investigates the social factors that restrict green development,encompassing social structures,social concepts,social systems,and social behaviors.Finally,within the framework of the“green”discipline system in environmental sociology,this paper proposes specific measures such as restructuring social systems and transforming production modes,lifestyles,and consumption patterns to promote green development.

The Thought of the Oneness Between Man and Nature in Walden

From the view of the ecological theory, this paper tries to analyze that Thoreau uses Chinese traditional philosophical thought--- the oneness of man and nature to deal with the relationship of human beings and the nature in Walden.