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Arctic Sea Ice Variations in the First Half of the 20th Century:A New Reconstruction Based on Hydrometeorological Data
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作者 Vladimir A.SEMENOV Tatiana A.ALDONINA +2 位作者 Fei LI Noel Sebastian KEENLYSIDE Lin WANG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第8期1483-1495,1686-1693,共21页
The shrinking Arctic sea-ice area(SIA) in recent decades is a striking manifestation of the ongoing climate change.Variations of the Arctic sea ice have been continuously observed by satellites since 1979, relatively ... The shrinking Arctic sea-ice area(SIA) in recent decades is a striking manifestation of the ongoing climate change.Variations of the Arctic sea ice have been continuously observed by satellites since 1979, relatively well monitored since the 1950s, but are highly uncertain in the earlier period due to a lack of observations. Several reconstructions of the historical gridded sea-ice concentration(SIC) data were recently presented based on synthesized regional sea-ice observations or by applying a hybrid model–empirical approach. Here, we present an SIC reconstruction for the period1901–2019 based on established co-variability between SIC and surface air temperature, sea surface temperature, and sea level pressure patterns. The reconstructed sea-ice data for March and September are compared to the frequently used Had ISST1.1 and SIBT1850 datasets. Our reconstruction shows a large decrease in SIA from the 1920 to 1940 concurrent with the Early 20th Century Warming event in the Arctic. Such a negative SIA anomaly is absent in Had ISST1.1 data. The amplitude of the SIA anomaly reaches about 0.8 mln km^(2) in March and 1.5 mln km^(2) in September. The anomaly is about three times stronger than that in the SIBT1850 dataset. The larger decrease in SIA in September is largely due to the stronger SIC reduction in the western sector of the Arctic Ocean in the 70°–80°N latitudinal zone. Our reconstruction provides gridded monthly data that can be used as boundary conditions for atmospheric reanalyses and model experiments to study the Arctic climate for the first half of the 20th century. 展开更多
关键词 Arctic sea ice Arctic climate early 20th century warming climate variability
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Women in the Musical Culture of Danzig in the First Half of the 20th Century
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作者 Joanna Schiller-Rydzewska 《Cultural and Religious Studies》 2023年第1期1-8,共8页
The musical culture of pre-war Danzig/Gdansk remains an area that is not well enough recognized in the scholarly literature.Numerous traces of this musical life are preserved in the collections of the Gdansk Library o... The musical culture of pre-war Danzig/Gdansk remains an area that is not well enough recognized in the scholarly literature.Numerous traces of this musical life are preserved in the collections of the Gdansk Library of the Polish Academy of Sciences.The collection ranges from scholarly publications and scores to an extensive number of concert programs and posters.The collection testifies to the dynamism and diversity of the city’s pre-war musical life.Notable among the collected materials is the role of female figures-composers,singers,and instrumentalists who made significant contributions to the shape of Gdansk musical life.In this article,I will present forgotten profiles of musically committed women:Martha Reincke,Ella Mertins,and Lotte Prins.In light of the surviving materials,it can be assumed that they were significant figures in the musical culture and social life of the city. 展开更多
关键词 20th century music in Gdansk/Danzig women in musical culture Gdansk Library musical culture of Gdansk/Danzig
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Restoring 20th Century Architecture:Few Words about a Possible Theory
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作者 Susanna Caccia Gherardini 《Journal of Civil Engineering and Architecture》 2023年第11期536-538,共3页
The restoration of twentieth-century architecture has led the discipline to develop a solid theory which,considering the complexity of new issues to be resolved,can provide useful instruments,above all critical ones,f... The restoration of twentieth-century architecture has led the discipline to develop a solid theory which,considering the complexity of new issues to be resolved,can provide useful instruments,above all critical ones,for operational practice. 展开更多
关键词 20th century architecture restoration PRESERVATION HERITAGE
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A New Chromatic Vision:The Early Impact of Color Photography on the Representation of Architecture
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作者 Angelo Maggi 《Journal of Civil Engineering and Architecture》 2023年第11期545-547,共3页
The role of color photography in the representation of architecture is a subject little investigated by architectural historiography.The link between the color values of architectural design and its visual transmissio... The role of color photography in the representation of architecture is a subject little investigated by architectural historiography.The link between the color values of architectural design and its visual transmission in the early phase of modernism was certainly problematic.Color photography had an undeniable impact on architectural color in practice:color photographs in books and periodicals published between the 1940s and 1960s clearly influenced the use of color in architectural design. 展开更多
关键词 20th century architecture COLOR PHOTOGRAPHY HISTORIOGRAPHY
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How Much Digital Activism Plays a Role in Political Activism: A Case Study of Morocco's February 20th Movement
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作者 Souad Slaoui 《Journalism and Mass Communication》 2014年第3期163-171,共9页
The present paper seeks to investigate the extent to which digital activism plays a role in political activism in Morocco through the intersection between women and young activists movement and the social media. By do... The present paper seeks to investigate the extent to which digital activism plays a role in political activism in Morocco through the intersection between women and young activists movement and the social media. By doing so the author argues that while facebook and the Moroccan political arena are Male dominated public areas, young female activists have emerged as prominent leaders in both spaces. The author will more particularly explain why female and youth activists are important in the current state of Moroccan politics. Next, the author provides a discussion of the February 20th Movement, and the movement's utilization of Facebook. It will show that young female activists involved in the February 20th Movement have used Facebook in unique and creative ways to further the Movement. 展开更多
关键词 Morocco digital activism Facebook February 20th Movement
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Promote the All-round Development of China's Human Right Cause in the New Era——Summary of the Symposium on “Deeply Studying and Implementing the Spirit of the 20th CPC National Congress and Adhering to the Chinese Path of Human Rights Development”
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作者 杨盈龙 NI Weisi 《The Journal of Human Rights》 2023年第1期212-226,共15页
On November 8, 2022, the symposium on “Deeply Studying and Implementing the Spirit of the 20thCPC National Congress and Adhering to the Chinese Path of Human Rights Development” was held by the China Society for Hum... On November 8, 2022, the symposium on “Deeply Studying and Implementing the Spirit of the 20thCPC National Congress and Adhering to the Chinese Path of Human Rights Development” was held by the China Society for Human Rights Studies in Beijing. Focusing on “the leadership of the CPC and human rights development”, “adapting Marxism to the Chinese context and the needs of our times and human rights theories in contemporary China”, “the Chinese path to modernization and the new form of human rights civilization”, “Chinese human rights solutions and global human rights governance”, “making a better China’s story of advancing human rights and constructing human rights discourse system”, and other topics, the participants reached broad consensus after discussion, and the symposium achieved fruitful results. 展开更多
关键词 the 20^(th)CPC National Congress adapting Marxism to the Chinese context and the needs of our times the Chinese path to modernization the new form of human rights civilization
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20(S/R)-人参皂苷Rg_3的制备及调节Th1/Th2免疫失衡活性 被引量:12
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作者 刘迎 陈妍心 +4 位作者 吴谦 黎鹏 李绪文 时晓磊 金永日 《高等学校化学学报》 SCIE EI CAS CSCD 北大核心 2018年第11期2419-2424,共6页
采用醋酸溶液作为提取溶剂,使西洋参叶中的二醇组人参皂苷在提取过程中发生降解,从而直接获得20(S)-人参皂苷Rg_3和20(R)-人参皂苷Rg_3,并对其调节Th1/Th2免疫失衡活性进行了研究.正交实验结果表明,当醋酸浓度为50%(体积分数),提取温度... 采用醋酸溶液作为提取溶剂,使西洋参叶中的二醇组人参皂苷在提取过程中发生降解,从而直接获得20(S)-人参皂苷Rg_3和20(R)-人参皂苷Rg_3,并对其调节Th1/Th2免疫失衡活性进行了研究.正交实验结果表明,当醋酸浓度为50%(体积分数),提取温度为80℃,提取时间为1 h时,20(S)-人参皂苷Rg_3和20(R)-人参皂苷Rg_3的转化率最高,分别为12. 30%和14. 80%.将20(S)-人参皂苷Rg_3和20(R)-人参皂苷Rg_3处理后的朗格汉斯状树突细胞(LDCs)分别作用于小鼠抗原诱导的Th1/Th2免疫失衡模型,发现细胞上层清液中IL-4的水平均显著降低,说明20(S)-人参皂苷Rg_3和20(R)-人参皂苷Rg_3对小鼠Th1/Th2免疫失衡具有调节作用.本文不仅建立了一种制备20(S)-人参皂苷Rg_3和20(R)-人参皂苷Rg_3的新方法,也为人参皂苷Rg_3在免疫系统疾病中的应用提供了新的科学依据. 展开更多
关键词 降解 提取 20(S/R)-人参皂苷Rg3 th1/th2免疫失衡
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CCR6-CCL20趋化轴在TH17细胞介导的肺纤维化大鼠肺组织中作用机制的研究 被引量:4
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作者 李树民 鲍文华 +5 位作者 王凤玲 张智勇 马雪梅 隋晓芳 杨晓东 李爽 《临床肺科杂志》 2015年第12期2177-2180,共4页
目的探讨CCR6-CCL20趋化轴在Th17细胞介导的肺纤维化大鼠肺组织中作用。方法随机将63只雄SD大鼠为:N组(生理盐水对照组)、B组(肺纤维化模型组)、D组(地塞米松治疗组),采用经气管内注入博来霉素致大鼠肺纤维化模型,对各组大鼠肺组织,分... 目的探讨CCR6-CCL20趋化轴在Th17细胞介导的肺纤维化大鼠肺组织中作用。方法随机将63只雄SD大鼠为:N组(生理盐水对照组)、B组(肺纤维化模型组)、D组(地塞米松治疗组),采用经气管内注入博来霉素致大鼠肺纤维化模型,对各组大鼠肺组织,分别采用HE染色观察病理变化;流式细胞术计数Th17细胞;免疫组化法评价CCR6表达;酶联免疫吸附试检测CCL20水平;结果 TH17细胞、CCR6、CCL20、在B、D组大鼠肺组织中不同时间点与N组相比较表达均明显增高(P<0.05),以造模7 d最为显著。TH17细胞计数水平与CCR6、CCL20表达有显著的相关性(Th17 vs.CCR6,r=0.693,P<0.01;Th17 vs CCL20,r=0.761,P<0.01)。结论 Th17细胞介导大鼠肺组织纤维化过程中,CCR6-CCL20起到重要的趋化Th17细胞作用。 展开更多
关键词 博来霉素 th17细胞 肺纤维化 趋化因子CCL20 趋化因子受体CCR6
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CCL20、CCR6和Th17在慢性牙周炎患者外周血中的表达 被引量:7
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作者 赵莉 杨柯 +2 位作者 李宝坤 王紫莹 陈晓涛 《北京口腔医学》 CAS 2020年第5期262-265,共4页
目的探讨趋化因子CCL20及其受体CCR6、Th17细胞在慢性牙周炎患者外周血中的表达。方法收集慢性牙周炎患者42例为病例组,牙周健康者30例为对照组。采用流式细胞术检测外周血Th17细胞表达水平,采用酶联免疫吸附实验(ELISA)测定血浆中CCL20... 目的探讨趋化因子CCL20及其受体CCR6、Th17细胞在慢性牙周炎患者外周血中的表达。方法收集慢性牙周炎患者42例为病例组,牙周健康者30例为对照组。采用流式细胞术检测外周血Th17细胞表达水平,采用酶联免疫吸附实验(ELISA)测定血浆中CCL20、CCR6及IL-17的浓度,并分析CCL20、IL-17及Th17与牙周袋深度(probing depth, PD)的相关关系。结果与正常组比较,病例组CCL20、CCR6、IL-17和Th17表达水平均明显增高,差异有统计学意义(P<0.05)。相关性分析表明CCL20、Th17和IL-17与PD呈正相关关系(P<0.05)。结论 CCL20、CCR6与Th17表达水平上调,推测与慢性牙周炎的发病有关。 展开更多
关键词 慢性牙周炎 th17细胞 CCR6 CCL20
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CCR6-CCL20对食管鳞癌患者体内Th17细胞分布的影响
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作者 蒋日月 陈德玉 +1 位作者 毛朝明 焦志军 《山东医药》 CAS 2012年第1期44-45,共2页
目的研究CCR6-CCL20对食管鳞癌患者体内Th17细胞分布的影响。方法采用流式细胞术检测食管鳞癌患者手术切除的癌组织、癌旁组织及外周血中Th17细胞的比例及CCR6+Th17细胞的比例。RT-PCR方法检测组织中CCL20 mRNA水平。结果与癌旁组织及... 目的研究CCR6-CCL20对食管鳞癌患者体内Th17细胞分布的影响。方法采用流式细胞术检测食管鳞癌患者手术切除的癌组织、癌旁组织及外周血中Th17细胞的比例及CCR6+Th17细胞的比例。RT-PCR方法检测组织中CCL20 mRNA水平。结果与癌旁组织及外周血相比,癌组织中Th17细胞明显升高(P<0.01);癌组织中CCR6+Th17细胞的比例高于癌旁组织及外周血(P<0.01);癌组织中CCL20 mRNA水平高于癌旁组织(P<0.01),并与Th17呈正相关。结论 CCR6-CCL20趋化轴可能在食管鳞癌患者Th17细胞浸润到肿瘤组织中发挥重要作用。 展开更多
关键词 食管肿瘤 th17细胞 CCR6 CCL20
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Review and prospects: in celebration of the 20th anniversary of Journal of Southeast University (English Edition)
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作者 徐金琪 《Journal of Southeast University(English Edition)》 EI CAS 2004年第4期521-524,共4页
The twenty years history of Journal of Southeast University (English Edition) and its significant achievements are briefly reviewed. Based on the experiences accumulated over its twenty years, some suggestions for imp... The twenty years history of Journal of Southeast University (English Edition) and its significant achievements are briefly reviewed. Based on the experiences accumulated over its twenty years, some suggestions for improving the quality of this English-language academic journal are proposed, including focusing on the report of the excellent disciplines of its sponsoring university, attracting high-level papers by giving the priority of publication, publishing special issues for experts and scholars at home and abroad, shortening publication period, and realizing the internationalization of the members of the editorial committee, etc. 展开更多
关键词 English-language academic journal Journal of Southeast University (English Edition) the 20th anniversary retrospection prospect suggestion
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古代教育人物群体的最初建构——以20世纪上半叶38种教育史著作为中心的考察
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作者 杜成宪 张月佳 《河北师范大学学报(教育科学版)》 北大核心 2023年第5期4-13,共10页
清末民国是中国教育史学科的初建时期,将什么样的古代人物写入教科书是学科建设的重要内容。截至1949年,全国共出版通论性质的中国教育史著作38种,共选入古代教育人物187人,按其选入频次可分为低频人物(162人)、中频人物(21人)和高频人... 清末民国是中国教育史学科的初建时期,将什么样的古代人物写入教科书是学科建设的重要内容。截至1949年,全国共出版通论性质的中国教育史著作38种,共选入古代教育人物187人,按其选入频次可分为低频人物(162人)、中频人物(21人)和高频人物(4人),有86人只被选入1次。从所选入人物及其频次看:这些著作以儒家思想为主线,宋以后则更侧重理学思想;从所选入人物的时代分布看:“厚古薄今”倾向明显;从所选中频人物、高频人物看:所选入人物身份比较混杂,教育家之外,传说人物、政治家、诗人、军事家、天文历算家、经学家等都有;从所选入人物学派背景看:春秋战国时期的人物体现出儒墨道法相争而以儒家为主导、儒道法相抗衡的现象,而两宋时期的人物则体现出学派蜂起而以程朱理学为主导的现实;从所选入人物的重要性看:所选入人物的重要性与被选入频次基本相称,同时也存在应当选入而未选入、所选入人物被高估或被低估等情况。在中国教育史学科体系中建构一个较为科学合理的古代教育人物群体具有重要的学术价值和社会价值。在具体实践中,可将20世纪上半叶我国38种教育史著作中中频人物、高频人物25人视为学科初建时期构建出来的古代教育人物基本群体,其中高频人物4人可以视为核心群体。基本群体基本能够反映中国古代教育的实际状况,但核心群体却不足以反映古代教育的核心价值。因此,如能让非儒家的一些中频人物进入核心群体,让一些低频人物进入基本群体,将会是理想的结果。 展开更多
关键词 20世纪上半叶 中国教育史著作 古代教育人物 选入频次 群体建构
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Progress in China's climate change study in the 20th century 被引量:21
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作者 翟盘茂 巢清尘 邹旭恺 《Journal of Geographical Sciences》 SCIE CSCD 2004年第z1期3-11,共9页
Studies on the 20th century climate change in China have revealed that under the background of global warming over the past century, climate in China has also experienced significant change with mean annual temperatur... Studies on the 20th century climate change in China have revealed that under the background of global warming over the past century, climate in China has also experienced significant change with mean annual temperature increased by about 0.5 oC. More reliable results for the latter part of the 20th century indicate that the largest warming occurred in Northwest China, North China and Northeast China, and the warming in winter is most significant. Although no obvious increase or decrease trends were detected for mean precipitation over China in the past half century, regional differences are very distinct. In the middle and lower reaches of the Yangtze River, precipitation increased, while that in the Yellow River Basin markedly decreased. Studies suggest that climate change in China seems to be related not only with the internal factors such as ENSO, PDO, and the others, but also with the anthropogenic effects such as greenhouse gas emissions, and land use. The future climate change studies in China seem to be important in narrowing understanding the nature of China's climate change and its main causes, since it is significant for projection and for impact assessment of climate change in the future. 展开更多
关键词 20th century climate change China
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Landscape pattern dynamics of water body in Kaifeng city in the 20th century 被引量:5
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作者 CAOXinxiang DINGShengyan 《Journal of Geographical Sciences》 SCIE CSCD 2005年第1期106-114,共9页
Landscape spatial pattern mainly refers to the distribution of patches, which are different in size and shape in space owing to the interaction of various ecological activities. In landscape ecology study, landscape p... Landscape spatial pattern mainly refers to the distribution of patches, which are different in size and shape in space owing to the interaction of various ecological activities. In landscape ecology study, landscape pattern has been one of the key study areas. Water body landscape plays an important role in the development history of a city, but at present city water body landscape in many cities has been destroyed, hence protecting water body in the city is becoming more and more important. In order to protect city water body landscape reasonably, the precondition is to probe the dynamics of water body landscape. Based on historical data and remote sensing data, six indexes including patch number, patch area, landscape dominance index, fractal dimension, patch density and connectivity index etc. were used to analyze landscape pattern dynamics of water body in Kaifeng city since the end of the Qing Dynasty (in the 20th century). The results showed: (1) Since the end of the Qing Dynasty, landscape area of water body in Kaifeng city increased first and then decreased from 1898 to 2002AD; the landscape dominant degree had the same changing tendency with the area. (2) Patch number of water body landscape in Kaifeng city had an increase from 1898 to 2002, but maximum area of patch, minimum area of patch and average area of patch decreased, which resulted in an increase in landscape fragment degree. (3) Connectivity index decreased and fractal dimension increased from 1898 to 2002. The reasons for these changes were the repeated overflows and flooding of the Yellow River and the influence of human activities. 展开更多
关键词 landscape pattern water body DYNAMICS Kaifeng city the early 20th century
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20 years'development of super rice in China--The 20th anniversary of the super rice in China 被引量:11
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作者 CHEN Wen-fu XU Zheng-jin TANG Liang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2017年第5期981-983,共3页
Rice (Oryza sativa L.) is originated from Asia and more than 90% of rice is produced inAsia. As the most important cereal crop in the world, rice is the staple food for over 1/3 global population, while this proport... Rice (Oryza sativa L.) is originated from Asia and more than 90% of rice is produced inAsia. As the most important cereal crop in the world, rice is the staple food for over 1/3 global population, while this proportion is over 60% in Asia (Wan 2010). In order to maintain the most important role that rice has played in Asian agriculture and ensure food security in the world, especially in Asia, 展开更多
关键词 In development of super rice in China YEARS the 20th anniversary of the super rice in China
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外周血CCL20与Th17细胞比例对病毒感染致心肌炎病情进展的影响 被引量:4
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作者 王宁 袁文清 胡会 《医学检验与临床》 2020年第4期10-13,54,共5页
目的:探讨外周血CCL20与Th17细胞比例与病毒感染致心肌炎(VMC)患者病情进展的关联关系。方法:选取2016年5月~2019年5月间,我院心血管内科收治的病毒性心肌炎患者96例作为研究对象,按病程分为急性期41例,慢性期20例,恢复期35例,另取健康... 目的:探讨外周血CCL20与Th17细胞比例与病毒感染致心肌炎(VMC)患者病情进展的关联关系。方法:选取2016年5月~2019年5月间,我院心血管内科收治的病毒性心肌炎患者96例作为研究对象,按病程分为急性期41例,慢性期20例,恢复期35例,另取健康受试者40例作为对照组。采用酶联免疫吸附(ELISA)试剂盒检测外周血CCL20和白介素-17(IL-17)水平,采用流式细胞仪检测外周血Th17细胞、CD4+细胞、CCR6^+细胞、Treg细胞,分析不同疾病阶段外周血CCL20、IL-17水平变化以及Th17细胞与CD4^+、CCR6^+、Treg比例的关系。结果:急性期组和慢性期组病毒性心肌炎患者的外周血CCL20和IL-17水平及Th17/CD4^+、CCR6^+/Th17等指标,均明显高于恢复期组和对照组,且慢性期组水平明显高于急性期组(P<0.05)。而Treg/CD4^+水平情况相反,急性期组和慢性期组均明显低于恢复期组和对照组,且慢性期组水平明显低于急性期组(P<0.05);相关性分析结果提示VMC患者外周血CCL20、IL-17与Th17/CD4^+呈正相关关系(r分别为0.463,0.412,P<0.05),而Treg/CD4^+与Th17/CD4^+呈负相关关系(r=-0.326,P<0.05)。结论:病毒性心肌炎患者急性期和慢性期外周血CCL20、IL-17水平升高,Th17细胞比例失衡,可能是疾病病程进展的重要机制。 展开更多
关键词 病毒性心肌炎 细胞因子 CCL20 th17细胞 流式细胞
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Changes of Air–sea Coupling in the North Atlantic over the 20th Century 被引量:2
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作者 YANG Yun WU Lixin 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2015年第4期445-456,共12页
Changes of air–sea coupling in the North Atlantic Ocean over the 20 th century are investigated using reanalysis data,climate model simulations, and observational data. It is found that the ocean-to-atmosphere feedba... Changes of air–sea coupling in the North Atlantic Ocean over the 20 th century are investigated using reanalysis data,climate model simulations, and observational data. It is found that the ocean-to-atmosphere feedback over the North Atlantic is significantly intensified in the second half of the 20 th century. This coupled feedback is characterized by the association between the summer North Atlantic Horseshoe(NAH) SST anomalies and the following winter North Atlantic Oscillation(NAO). The intensification is likely associated with the enhancement of the North Atlantic storm tracks as well as the NAH SST anomalies. Our study also reveals that most IPCC AR4 climate models fail to capture the observed NAO/NAH coupled feedback. 展开更多
关键词 air–sea coupling climate change North Atlantic Ocean 20th Century
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Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant 被引量:1
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作者 WanT ZhouX ChenG AnH ChenT ZhangW LiuS JiangY YangF WuY CaoX 《第二军医大学学报》 CAS CSCD 北大核心 2005年第7期771-771,共1页
Heat shock proteins (HSPs) are reported to act as effective adjuvants to elicit anti-tumor and anti-infection immunity. Here, we report that Hsp70-like protein 1 (Hsp70L1), a novel HSP derived from human dendritic cel... Heat shock proteins (HSPs) are reported to act as effective adjuvants to elicit anti-tumor and anti-infection immunity. Here, we report that Hsp70-like protein 1 (Hsp70L1), a novel HSP derived from human dendritic cells (DCs), has potent adjuvant effects that polarize responses toward Th1. With a calculated molecular weight of 54.8 kDa, Hsp70L1 is smaller in size than Hsp70 but resembles it both structurally and functionally. Hsp70L1 shares common receptors on DCs with Hsp70 and can interact with DCs, promoting DC maturation and stimulating secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1beta, tumor necrosis factor-alpha (TNF-alpha), and the chemokines IP-10, macrophage inflammatory protein-1alpha (MIP-1alpha), MIP-1beta, and normal T cell expressed and secreted (RANTES). The induction of interferon-gamma-inducible protein 10 (IP-10) secretion by Hsp70L1 is not shared by Hsp70, and other functional differences include more potent stimulation of DC IL-12p70, CC-chemokine, and CCR7 and CXCR4 expression by Hsp70L1. Immunization of mice with the hybrid peptide Hsp70L1-ovalbumin(OVA)(257-264) induces an OVA(257-264)-specific Th1 response and cytotoxic T lymphocyte (CTL) that results in significant inhibition of E.G7-OVA tumor growth. The ability of Hsp70L1 to activate DCs indicates its potential as a novel adjuvant for use with peptide immunizations; the Hsp70L1 antigen peptide hybrid may serve as a more effective vaccine for the control of cancer and infectious diseases. 展开更多
关键词 th heat Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a th1 polarizing adjuvant
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Precipitation Changes in Wet and Dry Seasons over the 20th Century Simulated by Two Versions of the FGOALS Model 被引量:2
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作者 MA Shuangmei ZHOU Tianjun 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2015年第6期839-854,共16页
Seasonal precipitation changes over the globe during the 20th century simulated by two versions of the Flexible Global Ocean-Atmosphere-Land System (FGOALS) model are assessed. The two model versions differ in terms... Seasonal precipitation changes over the globe during the 20th century simulated by two versions of the Flexible Global Ocean-Atmosphere-Land System (FGOALS) model are assessed. The two model versions differ in terms of their AGCM component, but the remaining parts of the system are almost identical. Both models reasonably reproduce the mean-state features of the timings of the wet and dry seasons and related precipitation amounts, with pattern correlation coefficients of 0.65-0.84 with observations. Globally averaged seasonal precipitation changes are analyzed. The results show that wet sea- sons get wetter and the annual range (precipitation difference between wet and dry seasons) increases during the 20th century in the two models, with positive trends covering most parts of the globe, which is consistent with observations. However, both models show a moistening dry season, which is opposite to observations. Analysis of the globally averaged moisture budget in the historical climate simulations of the two models shows little change in the horizontal moisture advection in both the wet and dry seasons. The globally averaged seasonal precipitation changes are mainly dominated by the changes in evaporation and vertical moisture advection. Evaporation and vertical moisture advection combine to make wet seasons wetter and enhance the annual range. In the dry season, the opposite change of evaporation and vertical moisture advection leads to an insignificant change in precipitation. Vertical moisture advection is the most important term that determines the changes in precipitation, wherein the thermodynamic component is dominant and the dynamic component tends to offset the effect of the thermodynamic component. 展开更多
关键词 20th century historical climate simulation FGOALS-g2 FGOALS-s2 wet season dry season precipitation change water vapor budget diagnosis
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不同浓度TH-628缓蚀剂对20#钢焊缝腐蚀影响 被引量:1
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作者 吴长江 《广州化工》 CAS 2018年第4期71-72,138,共3页
采用电化学噪声测试技术和电化学极化技术,研究了不同浓度TH-628缓蚀剂对20#钢及含有焊缝的20#钢腐蚀快慢的影响。试验结果表明:TH-628缓蚀剂能明显减缓循环水对20#钢和含有焊缝20#钢的腐蚀,随着TH-628缓蚀剂浓度的增加,腐蚀速率随之下... 采用电化学噪声测试技术和电化学极化技术,研究了不同浓度TH-628缓蚀剂对20#钢及含有焊缝的20#钢腐蚀快慢的影响。试验结果表明:TH-628缓蚀剂能明显减缓循环水对20#钢和含有焊缝20#钢的腐蚀,随着TH-628缓蚀剂浓度的增加,腐蚀速率随之下降。含焊缝试件腐蚀减缓速度低于不含焊缝试件,焊缝部位的腐蚀是整个设备的薄弱环节,建立在线腐蚀监测系统重点应考虑焊缝部位。 展开更多
关键词 电化学噪声 电化学极化 th-628缓蚀剂 20#钢 焊缝
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