To objectively obtain the three-dimensional coordinates of the projectile fuze proximity explosion when projectile intersects the head of missile target, we propose a dynamic seven photoelectric detection screen test ...To objectively obtain the three-dimensional coordinates of the projectile fuze proximity explosion when projectile intersects the head of missile target, we propose a dynamic seven photoelectric detection screen test method, which is made up of six plane detection screens and a flash photoelectric dynamic detection screen. The three-dimensional coordinates calculation model of the projectile proximity explosion position based on seven plane detection screens with dynamic characteristics is established.According to the relation of the dynamic seven photoelectric detection screen planes and the time values,the analytical function of the projectile proximity explosion position parameters under non-linear motion is derived. The projectile signal filtering method based on discrete wavelet transform is explored in this work. Additionally, the projectile signal recognition algorithm using an improved particle swarm is proposed. Based on the characteristics of the time duration and the signal peak error for the projectile passing through the detection screen, the signals attribution of the same projectile passing through six detection screens are analyzed for obtaining precise time values of the same projectile passing through the detection screens. On the basis of the projectile fuze proximity explosion test, the linear motion model and the proposed non-linear motion model are used to calculate and compare the same group of projectiles proximity explosion position parameters. The comparison of test results verifies that the proposed test method and calculation model in this work accurately obtain the actual projectile proximity explosion position parameters.展开更多
This study explores the quasi-real time inversion principle and precision estimation of three-dimensional coordinates of the epicenter, trigger time and magnitude of earthquakes with the aim to improve traditional met...This study explores the quasi-real time inversion principle and precision estimation of three-dimensional coordinates of the epicenter, trigger time and magnitude of earthquakes with the aim to improve traditional methods, which are flawed due to missing information or distortion in the seismograph records. The epicenter, trigger time and magnitude from the Lushan earthquake are inverted and analyzed based on high-frequency GNSS data. The inversion results achieved a high precision, which are consistent with the data published by the China Earthquake Administration. Moreover, it has been proven that the inversion method has good theoretical value and excellent application prospects.展开更多
In this paper, a transformation model named SARC(static-filter adjustment with restricted condition) is presented, which is more practical and more rigorous in theory and fitting any angle of rotation parameter. The t...In this paper, a transformation model named SARC(static-filter adjustment with restricted condition) is presented, which is more practical and more rigorous in theory and fitting any angle of rotation parameter. The transformation procedure is divided into 4 steps: ① the original and object coordinates can be regarded as observations with errors; ② rigorous formula is firstly deduced in order to compute the first approximation of the transformation parameters by use of four common points and the transformation equation is linearized; ③ calculate the most probable values and variances of the seven transformation parameters by SARC model; ④ to demonstrate validity of SARC , an example is given.展开更多
A new three-dimensional fundamental solution to the Stokes flow was proposed by transforming the solid harmonic functions in Lamb's solution into expressions in terms Of the oblate spheroidal coordinates. These fu...A new three-dimensional fundamental solution to the Stokes flow was proposed by transforming the solid harmonic functions in Lamb's solution into expressions in terms Of the oblate spheroidal coordinates. These fundamental solutions are advantageous in treating flows past an arbitrary number of arbitrarily positioned and oriented oblate spheroids. The least squares technique was adopted herein so that the convergence difficulties often encountered in solving three-dimensional problems were completely avoided. The examples demonstrate that present approach is highly accurate, consistently stable and computationally efficient. The oblate spheroid may be used to model a variety of particle shapes between a circular disk and a sphere. For the first time, the effect of various geometric factors on the forces and torques exerted on two oblate spheroids were systematically studied by using the proposed fundamental solutions. The generality of this approach was illustrated by two problems of three spheroids.展开更多
Starting from the finite rotation group,the author makes a penetrating study of 4 to 7-dimensional hypercube so that we have acquired the projection models of 4 to 7-dimeneional spatial rectangular coordinate systems ...Starting from the finite rotation group,the author makes a penetrating study of 4 to 7-dimensional hypercube so that we have acquired the projection models of 4 to 7-dimeneional spatial rectangular coordinate systems into the three-dimensional space to have the 4 to 7-dimensional geometric figures demonstrated correctly.展开更多
Through combined applications of the transfer-matrix method and asymptotic expansion technique,we formulate a theory to predict the three-dimensional response of micropolar plates.No ad hoc assumptions regarding throu...Through combined applications of the transfer-matrix method and asymptotic expansion technique,we formulate a theory to predict the three-dimensional response of micropolar plates.No ad hoc assumptions regarding through-thickness assumptions of the field variables are made,and the governing equations are two-dimensional,with the displacements and microrotations of the mid-plane as the unknowns.Once the deformation of the mid-plane is solved,a three-dimensional micropolar elastic field within the plate is generated,which is exact up to the second order except in the boundary region close to the plate edge.As an illustrative example,the bending of a clamped infinitely long plate caused by a uniformly distributed transverse force is analyzed and discussed in detail.展开更多
Hypoxia is a typical feature of the tumor microenvironment,one of the most critical factors affecting cell behavior and tumor progression.However,the lack of tumor models able to precisely emulate natural brain tumor ...Hypoxia is a typical feature of the tumor microenvironment,one of the most critical factors affecting cell behavior and tumor progression.However,the lack of tumor models able to precisely emulate natural brain tumor tissue has impeded the study of the effects of hypoxia on the progression and growth of tumor cells.This study reports a three-dimensional(3D)brain tumor model obtained by encapsulating U87MG(U87)cells in a hydrogel containing type I collagen.It also documents the effect of various oxygen concentrations(1%,7%,and 21%)in the culture environment on U87 cell morphology,proliferation,viability,cell cycle,apoptosis rate,and migration.Finally,it compares two-dimensional(2D)and 3D cultures.For comparison purposes,cells cultured in flat culture dishes were used as the control(2D model).Cells cultured in the 3D model proliferated more slowly but had a higher apoptosis rate and proportion of cells in the resting phase(G0 phase)/gap I phase(G1 phase)than those cultured in the 2D model.Besides,the two models yielded significantly different cell morphologies.Finally,hypoxia(e.g.,1%O2)affected cell morphology,slowed cell growth,reduced cell viability,and increased the apoptosis rate in the 3D model.These results indicate that the constructed 3D model is effective for investigating the effects of biological and chemical factors on cell morphology and function,and can be more representative of the tumor microenvironment than 2D culture systems.The developed 3D glioblastoma tumor model is equally applicable to other studies in pharmacology and pathology.展开更多
Liver regeneration and the development of effective therapies for liver failure remain formidable challenges in modern medicine.In recent years,the utilization of 3D cell-based strategies has emerged as a promising ap...Liver regeneration and the development of effective therapies for liver failure remain formidable challenges in modern medicine.In recent years,the utilization of 3D cell-based strategies has emerged as a promising approach for addressing these urgent clinical requirements.This review provides a thorough analysis of the application of 3D cell-based approaches to liver regeneration and their potential impact on patients with end-stage liver failure.Here,we discuss various 3D culture models that incorporate hepatocytes and stem cells to restore liver function and ameliorate the consequences of liver failure.Furthermore,we explored the challenges in transitioning these innovative strategies from preclinical studies to clinical applications.The collective insights presented herein highlight the significance of 3D cell-based strategies as a transformative paradigm for liver regeneration and improved patient care.展开更多
Electrocatalytic nitrate reduction reaction has attracted increasing attention due to its goal of low carbon emission and environmental protection.Here,we report an efficient NitRR catalyst composed of single Mn sites...Electrocatalytic nitrate reduction reaction has attracted increasing attention due to its goal of low carbon emission and environmental protection.Here,we report an efficient NitRR catalyst composed of single Mn sites with atomically dispersed oxygen(O)coordination on bacterial cellulose-converted graphitic carbon(Mn-O-C).Evidence of the atomically dispersed Mn-(O-C_(2))_(4)moieties embedding in the exposed basal plane of carbon surface is confirmed by X-ray absorption spectroscopy.As a result,the as-synthesized Mn-O-C catalyst exhibits superior NitRR activity with an NH_(3)yield rate(RNH_(3))of 1476.9±62.6μg h^(−1)cm^(−2)at−0.7 V(vs.reversible hydrogen electrode,RHE)and a faradaic efficiency(FE)of 89.0±3.8%at−0.5 V(vs.RHE)under ambient conditions.Further,when evaluated with a practical flow cell,Mn-O-C shows a high RNH_(3)of 3706.7±552.0μg h^(−1)cm^(−2)at a current density of 100 mA cm−2,2.5 times of that in the H cell.The in situ FT-IR and Raman spectroscopic studies combined with theoretical calculations indicate that the Mn-(O-C_(2))_(4)sites not only effectively inhibit the competitive hydrogen evolution reaction,but also greatly promote the adsorption and activation of nitrate(NO_(3)^(−)),thus boosting both the FE and selectivity of NH_(3)over Mn-(O-C_(2))_(4)sites.展开更多
Spinal cord injury is considered one of the most difficult injuries to repair and has one of the worst prognoses for injuries to the nervous system.Following surgery,the poor regenerative capacity of nerve cells and t...Spinal cord injury is considered one of the most difficult injuries to repair and has one of the worst prognoses for injuries to the nervous system.Following surgery,the poor regenerative capacity of nerve cells and the generation of new scars can make it very difficult for the impaired nervous system to restore its neural functionality.Traditional treatments can only alleviate secondary injuries but cannot fundamentally repair the spinal cord.Consequently,there is a critical need to develop new treatments to promote functional repair after spinal cord injury.Over recent years,there have been seve ral developments in the use of stem cell therapy for the treatment of spinal cord injury.Alongside significant developments in the field of tissue engineering,three-dimensional bioprinting technology has become a hot research topic due to its ability to accurately print complex structures.This led to the loading of three-dimensional bioprinting scaffolds which provided precise cell localization.These three-dimensional bioprinting scaffolds co uld repair damaged neural circuits and had the potential to repair the damaged spinal cord.In this review,we discuss the mechanisms underlying simple stem cell therapy,the application of different types of stem cells for the treatment of spinal cord injury,and the different manufa cturing methods for three-dimensional bioprinting scaffolds.In particular,we focus on the development of three-dimensional bioprinting scaffolds for the treatment of spinal cord injury.展开更多
The 2D limit equilibrium method is widely used for slope stability analysis.However,with the advancement of dump engineering,composite slopes often exhibit significant 3D mechanical effects.Consequently,it is of signi...The 2D limit equilibrium method is widely used for slope stability analysis.However,with the advancement of dump engineering,composite slopes often exhibit significant 3D mechanical effects.Consequently,it is of significant importance to develop an effective 3D stability calculation method for composite slopes to enhance the design and stability control of open-pit slope engineering.Using the composite slope formed by the mining stope and inner dump in Baiyinhua No.1 and No.2 open-pit coal mine as a case study,this research investigates the failure mode of composite slopes and establishes spatial shape equations for the sliding mass.By integrating the shear resistance and sliding force of each row of microstrip columns onto the bottom surface of the strip corresponding to the main sliding surface,a novel 2D equivalent physical and mechanical parameters analysis method for the strips on the main sliding surface of 3D sliding masses is proposed.Subsequently,a comprehensive 3D stability calculation method for composite slopes is developed,and the quantitative relationship between the coordinated development distance and its 3D stability coefficients is examined.The analysis reveals that the failure mode of the composite slope is characterized by cutting-bedding sliding,with the arc serving as the side interface and the weak layer as the bottom interface,while the destabilization mechanism primarily involves shear failure.The spatial form equation of the sliding mass comprises an ellipsoid and weak plane equation.The analysis revealed that when the coordinated development distance is 1500 m,the error rate between the 3D stability calculation result and the 2D stability calculation result of the composite slope is less than 8%,thereby verifying the proposed analytical method of equivalent physical and mechanical parameters and the 3D stability calculation method for composite slopes.Furthermore,the3D stability coefficient of the composite slope exhibits an exponential correlation with the coordinated development distance,with the coefficient gradually decreasing as the coordinated development distance increases.These findings provide a theoretical guideline for designing similar slope shape parameters and conducting stability analysis.展开更多
The title coordination polymer including two crystallographically independent Co2+ ions is hydrothermally synthesized, in which the Co(1) 2+ ion is four-coordinated by two carboxylate oxygen atoms from two differe...The title coordination polymer including two crystallographically independent Co2+ ions is hydrothermally synthesized, in which the Co(1) 2+ ion is four-coordinated by two carboxylate oxygen atoms from two different 5-(benzoic acid-4-yldiazenyl)isophthalate (byip3-) anions and two nitrogen atoms from two distinct 1,4-bis(imidazol-1-ylmethyl) benzene (bix) ligands displaying a tetrahedral geometry. The Co(2) 2+ ion is six-coordinated by two water molecules at the apical positions, and two carboxylate oxygen atoms and two nitrogen atoms at the equatorial positions, affording a slightly distorted octahedron. Two Co(1)2+ and two Co(2)2+ ions are linked together by four byip3- anions forming a 44-membered motif and these motifs are further arranged into a three-dimensional framework through bix ligands along the a axis with a larger channel (ca. 22.70×11.01). Each individual network interpenetrates with the other identical network in a parallel fashion to generate a 2-fold interpenetrating array with the {62.84}{63}2{64.82}2 topology.展开更多
A novel coordination polymer [Zn2(BTA)2(TDC)]n(HBTA = benzotriazole, H2TDC = thiophene-2,5-dicarboxylic acid) has been synthesized by the reaction of zinc(Ⅱ), H2TDC and HBTA. This compound is fully structural...A novel coordination polymer [Zn2(BTA)2(TDC)]n(HBTA = benzotriazole, H2TDC = thiophene-2,5-dicarboxylic acid) has been synthesized by the reaction of zinc(Ⅱ), H2TDC and HBTA. This compound is fully structurally characterized by elemental analysis, IR, and single-crystal X-ray crystallography. The bulk new materials were further identified by X-ray powder diffraction. Compound 1 crystallizes in the orthorhombic system, space group Pbcn, with a = 9.8825(8), b = 9.4047(8), c = 20.5567(17) , V = 1910.6(3) -3, C(18)H(10)N6O4SZn2, Mr = 537.12, Dc = 1.867 g/cm-3, μ(MoK α) = 2.662 mm-(-1), F(000) = 1072, Z = 4, S = 1.058, the final R = 0.0201 and w R = 0.0530 for 1700 observed reflections(I 2σ(I)). Its compositional stability and photoluminescence properties were further investigated to establish the structure-property relationships. Structural analysis reveals that this compound is a 3D(4, 4)-connected framework with the(6-6)(6-4·8-2) topology.展开更多
Two coordination polymers with 1,4-benzenedicarboxylic acid(H2BDC) ligand, namely, [Tb3(BDC)(4.5)(H2O)(DMF)2]n (1) and [Tb2(BDC)3(H2O)2(DMF)2]n(2), have been synthesized and characterized. Both com...Two coordination polymers with 1,4-benzenedicarboxylic acid(H2BDC) ligand, namely, [Tb3(BDC)(4.5)(H2O)(DMF)2]n (1) and [Tb2(BDC)3(H2O)2(DMF)2]n(2), have been synthesized and characterized. Both compounds crystallize in the triclinic system, space group P1. For compound 1, a = 10.8528(5), b = 12.2516(5), c = 16.9031(7) A, α = 104.462(1), β = 93.659(1), γ = 101.404(1)°, V = 2118.1(2) A^3, Z = 2, C(42)H(34)N2O(21)Tb3, Mr = 1379.47, Dc = 2.163 g/cm^3, μ = 5.045 mm^-1, F(000) = 1326, the final R = 0.0212 and wR = 0.0570 for 8592 observed reflections with I 〉 2σ(I). For compound 2, a = 8.547(1), b = 10.170(1), c = 11.192(1)A?, α = 65.531(1), β = 71.886(1), γ = 78.796(1)°, V = 839.2(2) A^3, Z = 1, C(30)H(30)N2O(16)Tb2, Mr = 992.40, Dc = 1.964 g/cm^3, μ = 4.257 mm^-1, F(000) = 482, the final R = 0.0220 and wR = 0.0649 for 3626 observed reflections with I 〉 2σ(I). The compounds exhibit different structural topologies depending on the nature of templating agents in the reactions though the templating agents are not incorporated in the final solids. Compound 1 exhibits a three-dimensional(3D) framework based on the rod-shaped terbium-carboxylate building blocks constructed from linear trinuclear Tb3 units. Compound 2 has a 3D framework containing two interpenetrating pcu topological networks based on the 6-connected dinuclear Tb2 secondary building units. Photoluminescence studies show both compounds exhibit typical Tb(Ⅲ) luminescence emissions. An efficient ligand-to-Tb(Ⅲ) energy transfer is observed in the emission spectra for both compounds.展开更多
A new metal-organic coordination polymer [Zn1.5(PDB)(bix)0.5(μ2-OH)]2n 1 (H2PDB = pyridine-3,4-dicarboxylic acid, bix = 1,4-bis(imidazol-1-ylmethyl)-benzene) has been hydrothermally synthesized and structur...A new metal-organic coordination polymer [Zn1.5(PDB)(bix)0.5(μ2-OH)]2n 1 (H2PDB = pyridine-3,4-dicarboxylic acid, bix = 1,4-bis(imidazol-1-ylmethyl)-benzene) has been hydrothermally synthesized and structurally characterized by elemental analysis, IR, TG and single-crystal X-ray diffraction. The title compound crystallizes in the monoclinic system, space group P2/c with a = 7.411(2), b = 7.848(3), c = 25.048(8), V = 1451.8(8)3, C28H22N6O10Zn3, Mr = 798.63, Dc = 1.827 g/cm3, μ(MoKα) = 2.529 mm-1, F(000) = 804, Z = 2, the final R = 0.0440 and wR = 0.1035 for 1952 observed reflections (I 2σ(I)). It exhibits a three-dimensional framework structure. Moreover, its luminescent property has been investigated in the solid state.展开更多
A new metal-organic coordination polymer [Ni2(NIPH)2(bimb)2.5(H2O)] n·3nH2O 1 (H2NIPH = 5-nitroisophthalic acid, bimb = 1,4-bis(imidazol-1-yl)-butane) has been hydrothermally synthesized and structurall...A new metal-organic coordination polymer [Ni2(NIPH)2(bimb)2.5(H2O)] n·3nH2O 1 (H2NIPH = 5-nitroisophthalic acid, bimb = 1,4-bis(imidazol-1-yl)-butane) has been hydrothermally synthesized and structurally characterized by elemental analysis, IR, TG and single-crystal X-ray diffraction. The title complex crystallizes in the orthorhombic system, space group P4(1)2(1)2 with a = 17.3533(16), b = 17.3533(16), c = 30.802(6)A, V= 9275(2)A^3, C41HagN12Ni2O16, Mr = 1083.34, Dc = 1.552 g/cm^3, p(MoKa) = 0.897 mm^-1, F(000) = 4504, Z = 8, the final R = 0.0383 and wR = 0.0952 for 7343 observed reflections (I〉 2σ(I)). It exhibits a three-dimensional network structure.展开更多
A new coordination polymer, [Zn2(m-bix)(p-bdc)2] (1), was synthesized under hydrothermal conditions by a reaction of 1,3-bis(imidazol-l-ylmethyl)benzene (m-bix), 1,3-benzene- dicarboxylic acid (H2p-bdc) an...A new coordination polymer, [Zn2(m-bix)(p-bdc)2] (1), was synthesized under hydrothermal conditions by a reaction of 1,3-bis(imidazol-l-ylmethyl)benzene (m-bix), 1,3-benzene- dicarboxylic acid (H2p-bdc) and Zn(NO3)2. The colorless block crystals of complex 1 (C30H22N408Zn2) belong to the triclinic system, space group P1 with a = 10.213(2), b = 12.052(2), c = 12.392(3) A, a = 82.97(3), β = 76.04(3), y = 78.02(3)°, V= 1443.8(5) A3, Z = 2, Dc = 1.604 g/cm3, Mr = 697.26, F(000) = 708, R = 0.0403 and wR = 0.0907 for 4886 observed reflections (1 〉 2σ(I)). In 1, the tetrahedral Zn11 cations are linked by [p-bdc]2- anions into 2D sql networks, which are further connected by bix ligands forming an interesting 2-fold 4,4-connected mog-type 3D network with a point symbol of {4·6^4·8}^2{4^2·6^2·8^2}. Complex 1 was characterized by elemental, IR spectroscopy, powder X-ray diffractions and thermalgravimetric analysis. In addition, complex 1 exhibits coordination induced photoluminescent property.展开更多
Two three-dimensional lanthanide(Ⅲ) coordination polymers with the formula [Ln(PYDC)(NA)(H2O)]n [Ln=Gd(1), Eu(2), H2PYDC=pyridine-2,5-bicarboxylic acid, HNA=nicotinic acid] have been hydrothermally synthe...Two three-dimensional lanthanide(Ⅲ) coordination polymers with the formula [Ln(PYDC)(NA)(H2O)]n [Ln=Gd(1), Eu(2), H2PYDC=pyridine-2,5-bicarboxylic acid, HNA=nicotinic acid] have been hydrothermally synthesized and characterized by elemental analysis, IR, and single crystal X-ray diffraction. The NA came from in situ decarboxylation of the part of PYDC. X-ray single crystal structural analyses reveal that complexes 1 and 2 are isomorphous, they possess the 43.63 topology assembled by Gd^3+/Eu^3+ and two different multidentate carboxylate ligands Magnetic measurements show that antiferromagnetic coupling exists between adjacent Gd^3+ ions in complex 1. The complex 2 exhibits the corresponding characteristic luminescence in the visible region under an excitation at 305 nm.展开更多
A toroidal soft x-ray imaging(T-SXRI)system has been developed to investigate threedimensional(3D)plasma physics on J-TEXT.This T-SXRI system consists of three sets of SXR arrays.Two sets are newly developed and locat...A toroidal soft x-ray imaging(T-SXRI)system has been developed to investigate threedimensional(3D)plasma physics on J-TEXT.This T-SXRI system consists of three sets of SXR arrays.Two sets are newly developed and located on the vacuum chamber wall at toroidal positionsφof 126.4°and 272.6°,respectively,while one set was established previously atφ=65.50.Each set of SXR arrays consists of three arrays viewing the plasma poloidally,and hence can be used separately to obtain SXR images via the tomographic method.The sawtooth precursor oscillations are measured by T-SXRI,and the corresponding images of perturbative SXR signals are successfully reconstructed at these three toroidal positions,hence providing measurement of the 3D structure of precursor oscillations.The observed 3D structure is consistent with the helical structure of the m/n=1/1 mode.The experimental observation confirms that the T-SXRI system is able to observe 3D structures in the J-TEXT plasma.展开更多
基金supported by Project of the National Natural Science Foundation of China (No.62073256, 61773305)the Key Science and Technology Program of Shaanxi Province (No.2020GY-125)Xi’an Science and Technology Innovation talent service enterprise project (No.2020KJRC0041)。
文摘To objectively obtain the three-dimensional coordinates of the projectile fuze proximity explosion when projectile intersects the head of missile target, we propose a dynamic seven photoelectric detection screen test method, which is made up of six plane detection screens and a flash photoelectric dynamic detection screen. The three-dimensional coordinates calculation model of the projectile proximity explosion position based on seven plane detection screens with dynamic characteristics is established.According to the relation of the dynamic seven photoelectric detection screen planes and the time values,the analytical function of the projectile proximity explosion position parameters under non-linear motion is derived. The projectile signal filtering method based on discrete wavelet transform is explored in this work. Additionally, the projectile signal recognition algorithm using an improved particle swarm is proposed. Based on the characteristics of the time duration and the signal peak error for the projectile passing through the detection screen, the signals attribution of the same projectile passing through six detection screens are analyzed for obtaining precise time values of the same projectile passing through the detection screens. On the basis of the projectile fuze proximity explosion test, the linear motion model and the proposed non-linear motion model are used to calculate and compare the same group of projectiles proximity explosion position parameters. The comparison of test results verifies that the proposed test method and calculation model in this work accurately obtain the actual projectile proximity explosion position parameters.
基金National Natural Science Foundation under Grant No.51574201Opening Fund of State Key Laboratory of Geohazard Prevention and Geoenvironment Protection(Chengdu University of Technology)under Grant No.SKLGP2016K017+2 种基金Open Research Fund by Sichuan Engineering Research Center for Emergency Mapping&Disaster Reduction under Grant No.K2015B008The State Administration of Work Safety under Grant No.2014_3335Soft Science Research Projects in Sichuan Province under Grant No.2015zr0049
文摘This study explores the quasi-real time inversion principle and precision estimation of three-dimensional coordinates of the epicenter, trigger time and magnitude of earthquakes with the aim to improve traditional methods, which are flawed due to missing information or distortion in the seismograph records. The epicenter, trigger time and magnitude from the Lushan earthquake are inverted and analyzed based on high-frequency GNSS data. The inversion results achieved a high precision, which are consistent with the data published by the China Earthquake Administration. Moreover, it has been proven that the inversion method has good theoretical value and excellent application prospects.
文摘In this paper, a transformation model named SARC(static-filter adjustment with restricted condition) is presented, which is more practical and more rigorous in theory and fitting any angle of rotation parameter. The transformation procedure is divided into 4 steps: ① the original and object coordinates can be regarded as observations with errors; ② rigorous formula is firstly deduced in order to compute the first approximation of the transformation parameters by use of four common points and the transformation equation is linearized; ③ calculate the most probable values and variances of the seven transformation parameters by SARC model; ④ to demonstrate validity of SARC , an example is given.
文摘A new three-dimensional fundamental solution to the Stokes flow was proposed by transforming the solid harmonic functions in Lamb's solution into expressions in terms Of the oblate spheroidal coordinates. These fundamental solutions are advantageous in treating flows past an arbitrary number of arbitrarily positioned and oriented oblate spheroids. The least squares technique was adopted herein so that the convergence difficulties often encountered in solving three-dimensional problems were completely avoided. The examples demonstrate that present approach is highly accurate, consistently stable and computationally efficient. The oblate spheroid may be used to model a variety of particle shapes between a circular disk and a sphere. For the first time, the effect of various geometric factors on the forces and torques exerted on two oblate spheroids were systematically studied by using the proposed fundamental solutions. The generality of this approach was illustrated by two problems of three spheroids.
文摘Starting from the finite rotation group,the author makes a penetrating study of 4 to 7-dimensional hypercube so that we have acquired the projection models of 4 to 7-dimeneional spatial rectangular coordinate systems into the three-dimensional space to have the 4 to 7-dimensional geometric figures demonstrated correctly.
基金Project supported by the National Natural Science Foundation of China (No. 12072337)。
文摘Through combined applications of the transfer-matrix method and asymptotic expansion technique,we formulate a theory to predict the three-dimensional response of micropolar plates.No ad hoc assumptions regarding through-thickness assumptions of the field variables are made,and the governing equations are two-dimensional,with the displacements and microrotations of the mid-plane as the unknowns.Once the deformation of the mid-plane is solved,a three-dimensional micropolar elastic field within the plate is generated,which is exact up to the second order except in the boundary region close to the plate edge.As an illustrative example,the bending of a clamped infinitely long plate caused by a uniformly distributed transverse force is analyzed and discussed in detail.
基金supported by the National Natural Science Foundation of China (No. 52275291)the Fundamental Research Funds for the Central Universitiesthe Program for Innovation Team of Shaanxi Province,China (No. 2023-CX-TD-17)
文摘Hypoxia is a typical feature of the tumor microenvironment,one of the most critical factors affecting cell behavior and tumor progression.However,the lack of tumor models able to precisely emulate natural brain tumor tissue has impeded the study of the effects of hypoxia on the progression and growth of tumor cells.This study reports a three-dimensional(3D)brain tumor model obtained by encapsulating U87MG(U87)cells in a hydrogel containing type I collagen.It also documents the effect of various oxygen concentrations(1%,7%,and 21%)in the culture environment on U87 cell morphology,proliferation,viability,cell cycle,apoptosis rate,and migration.Finally,it compares two-dimensional(2D)and 3D cultures.For comparison purposes,cells cultured in flat culture dishes were used as the control(2D model).Cells cultured in the 3D model proliferated more slowly but had a higher apoptosis rate and proportion of cells in the resting phase(G0 phase)/gap I phase(G1 phase)than those cultured in the 2D model.Besides,the two models yielded significantly different cell morphologies.Finally,hypoxia(e.g.,1%O2)affected cell morphology,slowed cell growth,reduced cell viability,and increased the apoptosis rate in the 3D model.These results indicate that the constructed 3D model is effective for investigating the effects of biological and chemical factors on cell morphology and function,and can be more representative of the tumor microenvironment than 2D culture systems.The developed 3D glioblastoma tumor model is equally applicable to other studies in pharmacology and pathology.
基金This work was supported by grants fromthe Sichuan Science and Technology Program(2023NSFSC1877).
文摘Liver regeneration and the development of effective therapies for liver failure remain formidable challenges in modern medicine.In recent years,the utilization of 3D cell-based strategies has emerged as a promising approach for addressing these urgent clinical requirements.This review provides a thorough analysis of the application of 3D cell-based approaches to liver regeneration and their potential impact on patients with end-stage liver failure.Here,we discuss various 3D culture models that incorporate hepatocytes and stem cells to restore liver function and ameliorate the consequences of liver failure.Furthermore,we explored the challenges in transitioning these innovative strategies from preclinical studies to clinical applications.The collective insights presented herein highlight the significance of 3D cell-based strategies as a transformative paradigm for liver regeneration and improved patient care.
基金the financial support from the Natural Science Foundation of China(Grant No.52172106)Anhui Provincial Natural Science Foundation(Grant Nos.2108085QB60 and 2108085QB61)China Postdoctoral Science Foundation(Grant Nos.2020M682057 and 2023T160651).
文摘Electrocatalytic nitrate reduction reaction has attracted increasing attention due to its goal of low carbon emission and environmental protection.Here,we report an efficient NitRR catalyst composed of single Mn sites with atomically dispersed oxygen(O)coordination on bacterial cellulose-converted graphitic carbon(Mn-O-C).Evidence of the atomically dispersed Mn-(O-C_(2))_(4)moieties embedding in the exposed basal plane of carbon surface is confirmed by X-ray absorption spectroscopy.As a result,the as-synthesized Mn-O-C catalyst exhibits superior NitRR activity with an NH_(3)yield rate(RNH_(3))of 1476.9±62.6μg h^(−1)cm^(−2)at−0.7 V(vs.reversible hydrogen electrode,RHE)and a faradaic efficiency(FE)of 89.0±3.8%at−0.5 V(vs.RHE)under ambient conditions.Further,when evaluated with a practical flow cell,Mn-O-C shows a high RNH_(3)of 3706.7±552.0μg h^(−1)cm^(−2)at a current density of 100 mA cm−2,2.5 times of that in the H cell.The in situ FT-IR and Raman spectroscopic studies combined with theoretical calculations indicate that the Mn-(O-C_(2))_(4)sites not only effectively inhibit the competitive hydrogen evolution reaction,but also greatly promote the adsorption and activation of nitrate(NO_(3)^(−)),thus boosting both the FE and selectivity of NH_(3)over Mn-(O-C_(2))_(4)sites.
基金supported by the National Natural Science Foundation of China,No.82171380(to CD)Jiangsu Students’Platform for Innovation and Entrepreneurship Training Program,No.202110304098Y(to DJ)。
文摘Spinal cord injury is considered one of the most difficult injuries to repair and has one of the worst prognoses for injuries to the nervous system.Following surgery,the poor regenerative capacity of nerve cells and the generation of new scars can make it very difficult for the impaired nervous system to restore its neural functionality.Traditional treatments can only alleviate secondary injuries but cannot fundamentally repair the spinal cord.Consequently,there is a critical need to develop new treatments to promote functional repair after spinal cord injury.Over recent years,there have been seve ral developments in the use of stem cell therapy for the treatment of spinal cord injury.Alongside significant developments in the field of tissue engineering,three-dimensional bioprinting technology has become a hot research topic due to its ability to accurately print complex structures.This led to the loading of three-dimensional bioprinting scaffolds which provided precise cell localization.These three-dimensional bioprinting scaffolds co uld repair damaged neural circuits and had the potential to repair the damaged spinal cord.In this review,we discuss the mechanisms underlying simple stem cell therapy,the application of different types of stem cells for the treatment of spinal cord injury,and the different manufa cturing methods for three-dimensional bioprinting scaffolds.In particular,we focus on the development of three-dimensional bioprinting scaffolds for the treatment of spinal cord injury.
基金supported by the National Natural Science Foundation of China (No.52374124)National Youth Science Foundation of China (No.52204135)+3 种基金Xing Liao Talent Plan (No.XLYC2202004)Young Elite Scientists Sponsorship Program by CAST (No.2023QNRC001)Liaoning Province International Science and Technology Cooperation Plan (No.2022JH2/1070004)Liaoning Natural Science Foundation Program (No.2022-BS-327)。
文摘The 2D limit equilibrium method is widely used for slope stability analysis.However,with the advancement of dump engineering,composite slopes often exhibit significant 3D mechanical effects.Consequently,it is of significant importance to develop an effective 3D stability calculation method for composite slopes to enhance the design and stability control of open-pit slope engineering.Using the composite slope formed by the mining stope and inner dump in Baiyinhua No.1 and No.2 open-pit coal mine as a case study,this research investigates the failure mode of composite slopes and establishes spatial shape equations for the sliding mass.By integrating the shear resistance and sliding force of each row of microstrip columns onto the bottom surface of the strip corresponding to the main sliding surface,a novel 2D equivalent physical and mechanical parameters analysis method for the strips on the main sliding surface of 3D sliding masses is proposed.Subsequently,a comprehensive 3D stability calculation method for composite slopes is developed,and the quantitative relationship between the coordinated development distance and its 3D stability coefficients is examined.The analysis reveals that the failure mode of the composite slope is characterized by cutting-bedding sliding,with the arc serving as the side interface and the weak layer as the bottom interface,while the destabilization mechanism primarily involves shear failure.The spatial form equation of the sliding mass comprises an ellipsoid and weak plane equation.The analysis revealed that when the coordinated development distance is 1500 m,the error rate between the 3D stability calculation result and the 2D stability calculation result of the composite slope is less than 8%,thereby verifying the proposed analytical method of equivalent physical and mechanical parameters and the 3D stability calculation method for composite slopes.Furthermore,the3D stability coefficient of the composite slope exhibits an exponential correlation with the coordinated development distance,with the coefficient gradually decreasing as the coordinated development distance increases.These findings provide a theoretical guideline for designing similar slope shape parameters and conducting stability analysis.
基金Supported by the Natural Science Foundation of Henan Province (No. 102300410021 and 102300410093)
文摘The title coordination polymer including two crystallographically independent Co2+ ions is hydrothermally synthesized, in which the Co(1) 2+ ion is four-coordinated by two carboxylate oxygen atoms from two different 5-(benzoic acid-4-yldiazenyl)isophthalate (byip3-) anions and two nitrogen atoms from two distinct 1,4-bis(imidazol-1-ylmethyl) benzene (bix) ligands displaying a tetrahedral geometry. The Co(2) 2+ ion is six-coordinated by two water molecules at the apical positions, and two carboxylate oxygen atoms and two nitrogen atoms at the equatorial positions, affording a slightly distorted octahedron. Two Co(1)2+ and two Co(2)2+ ions are linked together by four byip3- anions forming a 44-membered motif and these motifs are further arranged into a three-dimensional framework through bix ligands along the a axis with a larger channel (ca. 22.70×11.01). Each individual network interpenetrates with the other identical network in a parallel fashion to generate a 2-fold interpenetrating array with the {62.84}{63}2{64.82}2 topology.
基金Supported by the Science and technology development plan of Jilin province(20150520006JH)Science and technology research project of Education Department of Jilin province(2016219)
文摘A novel coordination polymer [Zn2(BTA)2(TDC)]n(HBTA = benzotriazole, H2TDC = thiophene-2,5-dicarboxylic acid) has been synthesized by the reaction of zinc(Ⅱ), H2TDC and HBTA. This compound is fully structurally characterized by elemental analysis, IR, and single-crystal X-ray crystallography. The bulk new materials were further identified by X-ray powder diffraction. Compound 1 crystallizes in the orthorhombic system, space group Pbcn, with a = 9.8825(8), b = 9.4047(8), c = 20.5567(17) , V = 1910.6(3) -3, C(18)H(10)N6O4SZn2, Mr = 537.12, Dc = 1.867 g/cm-3, μ(MoK α) = 2.662 mm-(-1), F(000) = 1072, Z = 4, S = 1.058, the final R = 0.0201 and w R = 0.0530 for 1700 observed reflections(I 2σ(I)). Its compositional stability and photoluminescence properties were further investigated to establish the structure-property relationships. Structural analysis reveals that this compound is a 3D(4, 4)-connected framework with the(6-6)(6-4·8-2) topology.
基金Supported by the NNSFC(21361011)the Provincial Natural Science Foundation of Jiangxi(20151BAB203002)+1 种基金the Project of Education Department of Jiangxi Province(GJJ14235)the Open Project Program of Key Laboratory of Functional Small Organic Molecule,Ministry of Education,Jiangxi Normal University(KLFS-KF-201412)
文摘Two coordination polymers with 1,4-benzenedicarboxylic acid(H2BDC) ligand, namely, [Tb3(BDC)(4.5)(H2O)(DMF)2]n (1) and [Tb2(BDC)3(H2O)2(DMF)2]n(2), have been synthesized and characterized. Both compounds crystallize in the triclinic system, space group P1. For compound 1, a = 10.8528(5), b = 12.2516(5), c = 16.9031(7) A, α = 104.462(1), β = 93.659(1), γ = 101.404(1)°, V = 2118.1(2) A^3, Z = 2, C(42)H(34)N2O(21)Tb3, Mr = 1379.47, Dc = 2.163 g/cm^3, μ = 5.045 mm^-1, F(000) = 1326, the final R = 0.0212 and wR = 0.0570 for 8592 observed reflections with I 〉 2σ(I). For compound 2, a = 8.547(1), b = 10.170(1), c = 11.192(1)A?, α = 65.531(1), β = 71.886(1), γ = 78.796(1)°, V = 839.2(2) A^3, Z = 1, C(30)H(30)N2O(16)Tb2, Mr = 992.40, Dc = 1.964 g/cm^3, μ = 4.257 mm^-1, F(000) = 482, the final R = 0.0220 and wR = 0.0649 for 3626 observed reflections with I 〉 2σ(I). The compounds exhibit different structural topologies depending on the nature of templating agents in the reactions though the templating agents are not incorporated in the final solids. Compound 1 exhibits a three-dimensional(3D) framework based on the rod-shaped terbium-carboxylate building blocks constructed from linear trinuclear Tb3 units. Compound 2 has a 3D framework containing two interpenetrating pcu topological networks based on the 6-connected dinuclear Tb2 secondary building units. Photoluminescence studies show both compounds exhibit typical Tb(Ⅲ) luminescence emissions. An efficient ligand-to-Tb(Ⅲ) energy transfer is observed in the emission spectra for both compounds.
基金Supported by the Science and Technology Development Project of Jilin Provincial Science&Technology Department(201205080)the Science and Technology Research Projects of the Education Department of Jilin Province(2012.358)
文摘A new metal-organic coordination polymer [Zn1.5(PDB)(bix)0.5(μ2-OH)]2n 1 (H2PDB = pyridine-3,4-dicarboxylic acid, bix = 1,4-bis(imidazol-1-ylmethyl)-benzene) has been hydrothermally synthesized and structurally characterized by elemental analysis, IR, TG and single-crystal X-ray diffraction. The title compound crystallizes in the monoclinic system, space group P2/c with a = 7.411(2), b = 7.848(3), c = 25.048(8), V = 1451.8(8)3, C28H22N6O10Zn3, Mr = 798.63, Dc = 1.827 g/cm3, μ(MoKα) = 2.529 mm-1, F(000) = 804, Z = 2, the final R = 0.0440 and wR = 0.1035 for 1952 observed reflections (I 2σ(I)). It exhibits a three-dimensional framework structure. Moreover, its luminescent property has been investigated in the solid state.
基金supported by the Science and Technology Development Project of Jilin Provincial Science & Technology Department (201205080)
文摘A new metal-organic coordination polymer [Ni2(NIPH)2(bimb)2.5(H2O)] n·3nH2O 1 (H2NIPH = 5-nitroisophthalic acid, bimb = 1,4-bis(imidazol-1-yl)-butane) has been hydrothermally synthesized and structurally characterized by elemental analysis, IR, TG and single-crystal X-ray diffraction. The title complex crystallizes in the orthorhombic system, space group P4(1)2(1)2 with a = 17.3533(16), b = 17.3533(16), c = 30.802(6)A, V= 9275(2)A^3, C41HagN12Ni2O16, Mr = 1083.34, Dc = 1.552 g/cm^3, p(MoKa) = 0.897 mm^-1, F(000) = 4504, Z = 8, the final R = 0.0383 and wR = 0.0952 for 7343 observed reflections (I〉 2σ(I)). It exhibits a three-dimensional network structure.
基金Support by the National Natural Science Foundation of China(21371052)
文摘A new coordination polymer, [Zn2(m-bix)(p-bdc)2] (1), was synthesized under hydrothermal conditions by a reaction of 1,3-bis(imidazol-l-ylmethyl)benzene (m-bix), 1,3-benzene- dicarboxylic acid (H2p-bdc) and Zn(NO3)2. The colorless block crystals of complex 1 (C30H22N408Zn2) belong to the triclinic system, space group P1 with a = 10.213(2), b = 12.052(2), c = 12.392(3) A, a = 82.97(3), β = 76.04(3), y = 78.02(3)°, V= 1443.8(5) A3, Z = 2, Dc = 1.604 g/cm3, Mr = 697.26, F(000) = 708, R = 0.0403 and wR = 0.0907 for 4886 observed reflections (1 〉 2σ(I)). In 1, the tetrahedral Zn11 cations are linked by [p-bdc]2- anions into 2D sql networks, which are further connected by bix ligands forming an interesting 2-fold 4,4-connected mog-type 3D network with a point symbol of {4·6^4·8}^2{4^2·6^2·8^2}. Complex 1 was characterized by elemental, IR spectroscopy, powder X-ray diffractions and thermalgravimetric analysis. In addition, complex 1 exhibits coordination induced photoluminescent property.
基金Supported by the Education Department Science Foundation of Liaoning Province(No.2008581)the Doctor Foundation of Liaoning Province(No.20071016)+1 种基金SRF for ROCS,SEM(No.200908)Liaoning BaiQian Wan Talents Program
文摘Two three-dimensional lanthanide(Ⅲ) coordination polymers with the formula [Ln(PYDC)(NA)(H2O)]n [Ln=Gd(1), Eu(2), H2PYDC=pyridine-2,5-bicarboxylic acid, HNA=nicotinic acid] have been hydrothermally synthesized and characterized by elemental analysis, IR, and single crystal X-ray diffraction. The NA came from in situ decarboxylation of the part of PYDC. X-ray single crystal structural analyses reveal that complexes 1 and 2 are isomorphous, they possess the 43.63 topology assembled by Gd^3+/Eu^3+ and two different multidentate carboxylate ligands Magnetic measurements show that antiferromagnetic coupling exists between adjacent Gd^3+ ions in complex 1. The complex 2 exhibits the corresponding characteristic luminescence in the visible region under an excitation at 305 nm.
基金supported by the National Magnetic Confinement Fusion Energy R&D Program of China(Nos.2018YFE0309100 and 2019YFE03010004)National Natural Science Foundation of China(No.51821005)。
文摘A toroidal soft x-ray imaging(T-SXRI)system has been developed to investigate threedimensional(3D)plasma physics on J-TEXT.This T-SXRI system consists of three sets of SXR arrays.Two sets are newly developed and located on the vacuum chamber wall at toroidal positionsφof 126.4°and 272.6°,respectively,while one set was established previously atφ=65.50.Each set of SXR arrays consists of three arrays viewing the plasma poloidally,and hence can be used separately to obtain SXR images via the tomographic method.The sawtooth precursor oscillations are measured by T-SXRI,and the corresponding images of perturbative SXR signals are successfully reconstructed at these three toroidal positions,hence providing measurement of the 3D structure of precursor oscillations.The observed 3D structure is consistent with the helical structure of the m/n=1/1 mode.The experimental observation confirms that the T-SXRI system is able to observe 3D structures in the J-TEXT plasma.