Antidiastole Value of Three-dimensional Ultrasonography and Power Doppler between Uterine Parenchyma Lumps and Endometrial Cancer:A Retrospective Study

Sometimes endometrial polyps,submucosal myomas,and endometrial cancer show similar findings under ultrasonography.The aim of this study was to assess the antidiastole value of blood flow parameters using three-dimensional(3D)power Doppler ultrasonography angiography(PDA)between endometrial cancer and uterine parenchyma lumps.The data of the blood flow indices in 3D-PDA including the vascularization index(VI),flow index(FI),and vascularization flow index(VFI)in 40 patients with endometrial cancer and 41 patients with uterine parenchyma lumps(endometrial polyps and submucosal myomas)were retrospectively analysed and compared utilizing Virtual Organ Computer-aided AnaLysis(VOCAL)software.The results showed that all the blood flow parameters(VI,FI,VFI)were significantly higher in women with endometrial cancer than in those with uterine parenchyma lumps(P<0.001).The area under the curve of ROC of VI,FI,and VFI was 0.98,0.84,and 0.97,respectively.Thus,the best predictor of endometrial carcinoma was VI with a sensitivity of 97.0% and a specificity of 91.0%.The optimal cutoff value of VI was 4.06%.Our data demonstrated that all of the blood flow signal parameters(including VI,FI,and VFI)in 3D power Doppler ultrasonography had significant antidiastole values between endometrial cancer and uterine parenchyma lumps to assist clinicians in properly diagnosing patients.

Real-time Three-Dimensional Color Doppler Flow Imaging： An Improved Technique for Quantitative Analysis of Aortic Regurgitation

The recently introduced real-time three-dimensional color Doppler flow imaging （RT-3D CDFI） technique provides a quick and accurate calculation of regurgitant jet volume （RJV） and fraction. In order to evaluate RT-3D CDFI in the noninvasive assessment of aortic RJV and regurgitant jet fraction （RJF） in patients with isolated aortic regurgitation, real-time three-dimensional echocardiographic studies were performed on 23 patients with isolated aortic regurgitation to obtain LV end-diastolic volumes （LVEDV）, end-systolic volumes （LVESV） and RJV, and then RJF could be calculated. The regurgitant volume （RV） and regurgitant fraction （RF） calculated by two-dimensional pulsed Doppler （2D-PD） method served as reference values. The results showed that aortic RJV measured by the RT-3D CDFI method showed a good correlation with the 2D-PD measurements （r= 0.93, Y=0.89X＋ 3.9, SEE= 8.6 mL, P〈0.001 ）; the mean （SD） difference between the two methods was - 1.5 （9.8） mL. % RJF estimated by the RT-3D CDFI method was also correlated well with the values obtained by the 2D-PD method （r=0.88, Y=0.71X＋ 14.8, SEE= 6.4 %, P〈0. 001）; the mean （SD） difference between the two methods was -1.2 （7.9） %. It was suggested that the newly developed RT-3D CDFI technique was feasible in the majority of patients. In patients with eccentric aortic regurgitation, this new modality provides additional information to that obtained from the two-dimensional examination, which overcomes the inherent limitations of two-dimensional echocardiography by depicting the full extent of the jet trajectory. In addition, the RT-3D CDFI method is quick and accurate in calculating RJV and RJF.

Implementation of a particle-in-cell method for the energy solver in 3D spherical geodynamic modeling

The thermal evolution of the Earth’s interior and its dynamic effects are the focus of Earth sciences.However,the commonly adopted grid-based temperature solver is usually prone to numerical oscillations,especially in the presence of sharp thermal gradients,such as when modeling subducting slabs and rising plumes.This phenomenon prohibits the correct representation of thermal evolution and may cause incorrect implications of geodynamic processes.After examining several approaches for removing these numerical oscillations,we show that the Lagrangian method provides an ideal way to solve this problem.In this study,we propose a particle-in-cell method as a strategy for improving the solution to the energy equation and demonstrate its effectiveness in both one-dimensional and three-dimensional thermal problems,as well as in a global spherical simulation with data assimilation.We have implemented this method in the open-source finite-element code CitcomS,which features a spherical coordinate system,distributed memory parallel computing,and data assimilation algorithms.

Changes in three-dimensional power Doppler ultrasound features before and after neoadjuvant chemotherapy for cervical cancer and their relationship with malignant molecule expression

Objective:To study the changes in three-dimensional power Doppler ultrasound features before and after neoadjuvant chemotherapy for cervical cancer and their relationship with malignant molecule expression.Methods: The patients who were diagnosed with cervical cancer and received neoadjuvant chemotherapy in Wuhan Red Cross Hospital between March 2015 and October 2017 were selected as the cervical cancer group, and the patients who received cervical biopsy and were diagnosed with stage I cervical intraepithelial neoplasia by pathological findings during the same period were selected as the control group. Before biopsy, three-dimensional power Doppler ultrasonography was performed to measure VI, FI and VFI;the tissues of cervical cancer group before and after chemotherapy as well as the biopsy tissues of control group were collected to measure the expression of proliferation genes, invasion genes and angiogenesis genes.Results: The VI, FI and VFI levels as well as the Piwil2 gene (Piwil2), CyclinD1, N-Myc downstream regulated gene 3 (NDRG3), CXC chemokine ligand 5 (CXCL5), cathepsin-L (CAT-L), EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1), angiotensin (Ang)1, Ang2 and angiopoietin-like protein 4 (ANGPTL4) mRNA expression levels in the tissues of cervical cancer group before and after chemotherapy were all significantly higher than those of control group whereas the thrombospondin 2 (THBS2), Smac gene (Smac), large tumor suppressor kinase 1 (LATS1), reversion-inducing-cysteine-rich protein with kazal motifs (RECK) and plas minogen activator inhibitor 1 (PAI-1) mRNA expression levels in the tissues were all significantly lower than those of control group, and the VI, FI and VFI levels as well as the Piwil2, CyclinD1, NDRG3, CXCL5, CAT-L, EFEMP1, Ang1, Ang2 and ANGPTL4 mRNA expression levels in the tissues of cervical cancer group after chemotherapy were all significantly lower than those before chemotherapy whereas the THBS2, Smac, LATS1, RECK and PAI-1 mRNA expression levels were all significantly higher than those before chemotherapy;the VI, FI and VFI levels in cervical cancer tissues were positively correlated with the Piwil2, CyclinD1, NDRG3, CXCL5, CAT-L, EFEMP1, Ang1, Ang2 and ANGPTL4 mRNA expression levels, and negatively correlated with the THBS2, Smac, LATS1, RECK and PAI-1 mRNA expression levels.Conclusion: The changes in the three-dimensional power Doppler ultrasound parameters before and after neoadjuvant chemotherapy for cervical cancer can reflect the changes in proliferation, invasion and angiogenesis gene expression in the lesions.

The Study of Ovarian Artery Hemodynamics in Patients with Infertility by Color Doppler Energy

Seventy four cases of infertility were examined to study the hemodynamics of the bilateral ovarian arteries at 21st day during the corpus luteum phase by color Doppler energy(CDE) and color Doppler flow imaging (CDFI). All the patients were verified by laparoscopy, fallopian tube patency examination and ovarian function test. Twenty two healthy women served as controls. The results showed that the difference of resistance index(RI)and pulsatility index (PI) of bilateral ovarian arteries between the infertility and the normal controls had statistical significance ( P <0.01), and the PI showed negative correlation with the thickness of endometrium (left side: r =0.724, P <0.01; right side: r =0.756, P <0.01). The results also showed that CDE was more sensitive than CDFI in displaying the ovarian arteries. It could be concluded that the elevated resistance of ovarian artery during the corpus luteum phase was one of the important factors that resulted in infertility.

Reflection of three-dimensional plane waves at the free surface of a rotating triclinic half-space under the context of generalized thermoelasticity

The reflection of three-dimensional(3D) plane waves in a highly anisotropic(triclinic) medium under the context of generalized thermoelasticity is studied. The thermoelastic nature of the 3D plane waves in an anisotropic medium is investigated in the perspective of the three-phase-lag(TPL), dual-phase-lag(DPL), Green-Naghdi-III(GNIII), Lord-Shulman(LS), and classical coupled(CL) theories. The reflection coefficients and energy ratios for all the reflected waves are obtained in a mathematical form. The rotational effects on the reflection characteristics of the 3D waves are discussed under the context of generalized thermoelasticity. Comparative analyses for the reflection coefficients of the waves among these generalized thermoelastic theories are performed. The energy ratios for each of the reflected waves establish the energy conservation law in the reflection phenomena of the plane waves. The highly anisotropic materials along with the rotation may have a significant role in the phenomenon of the reflection behavior of the 3D waves. Numerical computations are performed for the graphical representation of the study.

Simulation study on reconstruction model of three-dimensional temperature distribution within visible range in furnace

This paper presents a reconstruction model of three-dimensional temperature distribution in furnace based on radiative energy images captured by charge-coupled device （CCD） cameras within the visible wavelength range. Numerical simulation case was used in this study and a zigzag eccentric temperature distribution was assumed to verify the model. Least square QR-factorization （LSQR） method was introduced to deal with reconstruction equation. It is found that the reconstructed temperature distributions in low-temperature areas had some fluctuations and high-temperature areas were reconstructed well. The whole reconstruction relative error was mainly due to errors in low-temperature areas and the relative error for highest-temperature reconstruction was quite small.

Cosmology Should Directly Use the Doppler’s Formula to Calculate the Red Shift of Ia Supernova<br />—The Proofs That Metric Red Shift Is Inapplicable and Dark Energy Does Not Exist

The Doppler formula should be used directly to calculate red shift of Cosmology. The first is gravity, the second is the Doppler’s effect and the third is the Compton scattering. The red shift of cosmology is considered to be caused by the receding motions of celestial bodies, of which essence is the Doppler’s effect. However, the basic formula used to calculate the relationship between red shift and distance for Ia supernova in cosmology is z+1= R(t0)/R(t1)which is based on the R-W metric and related to the scalar factor R(t). This is different from the Doppler formula which is related to speed factor R(t). Because the R-W metric is only a mathematical structure of space, the metric red shift is not an independent law of physics, this inconsistence is not allowed in physics. It is proved strictly in this paper that the formula of metric red shift is only the result of the first order approximation. If higher order approximations are considered, we can obtain a restrict condition R(t). It indicates that if the formula of metric red shift holds, it can only be suitable to describe the spatial uniform expansion, unsuitable for the practical universal process with acceleration. The further study reveals that the R-W metric violates the invariability principle of light’s speed in vacuum. The time delay caused by

High-precision three-dimensional atom localization via probe absorption at room temperature

A scheme is used to explore the behavior of three-dimensional(3D)atom localization in a Y-type hot atomic system.We can obtain the position information of the atom due to the position-dependent atom–field interaction.We study the influences of the system parameters and the temperature on the atom localization.More interestingly,the atom can be localized in a subspace when the temperature is equal to 323 K.Moreover,a method is proposed to tune multiparameter for localizing the atom in a subspace.The result is helpful to achieve atom nanolithography,photonic crystal and measure the center-of-mass wave function of moving atoms.

Three-Dimensional Velocity Distribution Measurement Using Ultrasonic Velocity Profiler with Developed Transducer

This study describes an ultrasonic velocity profiler that uses a new ultrasonic array transducer with unique 5-element configuration, with all five elements acting as transmitters and four elements as receivers. The receivers are designed to reduce the amount of uncertainty. As the fluid moves through this setup, four Doppler frequencies are obtained. The multi-dimensional velocity information along the measurement line can be reconstructed. The transducer has a compact geometry suitable for a wide range of applications, including narrow flow areas. The transducer’s basic frequency and sound pressure are selected and evaluated to be compatible with the application. First, to confirm the measurement ability, the measurement of the developed system in two-dimensional flow is validated by comparing it to the theoretical data. The uncertainty of measurement was within 15%. Second, the three-dimensional measurement in turbulent and swirling flow is proved experimentally to check the applicability of the proposed technique.

A Three-Dimensional Prediction Method for Thermal Diffusion

A three-dimensional, first order turbulence closure, thermal diffusion model is described in this paper. The governing equations consist of an equation of continuity, three components of momentum, conservation equations for salt, temperature and subgridscale energy, and an equation of state. In the model, according to the hypothesis of Kolmogorov and Prandtl, the viscosity coefficient of turbulent flow of homogeneous fluid is related to the local turbulent energy, and the horizontal and vertical exchange coefficients of mass, heat and momentum are computed with the introduction of subgridscale turbulence energy. The governing equations are solved by finite difference techniques. This model is applied to the Jiaozhou bay to predict thermal pollution by the Huangdao power plant. An instantaneous tidal current field is computed, then the distribution of temperature increment is predicted, and finally the effect of wind stress on thermal discharge is discussed.

三维能量多普勒超声参数联合胎盘生长因子对早发型胎儿生长受限的预测价值

目的探讨三维能量多普勒超声参数联合胎盘生长因子(PLGF)对早发型胎儿生长受限(FGR)的预测价值。方法选取早发型FGR孕妇80例为FGR组,另选取同期产检健康孕妇50例为对照组。在孕11~13周+6对所有研究对象进行三维能量多普勒超声检查,收集胎盘容积(PV)、血管化指数(VI)、血流指数(FI)、血管化-血流指数(VFI)等指标。在孕14~16周+6检测所有研究对象血清PLGF水平。结果FGR组的PV、VI、FI、VFI以及血清PLGF水平均低于对照组,差异有统计学意义(P<0.05)。多元Logistic回归方程分析显示,PV、VI、FI、VFI以及血清PLGF水平过低是早发型FGR的危险因素(P<0.05)。受试者工作特征(ROC)曲线分析显示,PV、VI、VFI以及血清PLGF均对早发型FGR有一定的预测价值,曲线下面积分别为0.723(95%CI:0.629~0.817)、0.776(95%CI:0.693~0.860)、0746(95%CI:0.653~0.839)、0.799(95%CI:0.713~0.884),FI对早发型FGR的预测价值一般,曲线下面积为0.625(95%CI:0.524~0.725)。经分析显示,PLGF联合VI以及PLGF联合VFI对早发型FGR的预测价值较好,PLGF联合VI的敏感度、特异度和约登指数分别为86.25%、76.00%、0.623,PLGF联合VFI的敏感度、特异度和约登指数分别为81.25%、80.00%、0.613。结论三维能量多普勒超声参数联合PLGF对早发型FGR有一定的预测价值,可用于临床筛查早发型FGR高风险人群。

血清PLGF/sFlt-1联合胎盘3D-PDI对子痫前期的预测价值

目的探讨血清胎盘生长因子(PLGF)/可溶性血管内皮生长因子受体-1(sFlt-1)联合胎盘三维能量多普勒指数(3D-PDI)对子痫前期(PE)的预测价值。方法选取2021年1月至2022年12月于我院就诊且有PE高危因素的孕妇120例,随访至分娩后1周。于孕14~20周常规产检时检测血清PLGF和sFlt-1水平,并计算PLGF/sFlt-1比值,同时超声检测胎盘3D-PDI,包括血管化指数(VI)、血流指数(FI)、血管化-血流指数(VFI)。根据孕20周后是否发生PE,分为PE组(55例)和对照组(65例),根据病情轻重将PE组进一步分为非重度PE组(35例)和重度PE组(20例)。比较各组PLGF/sFlt-1及3D-PDI,并分析PLGF、sFlt-1与3D-PDI的相关性,绘制受试者操作特征(ROC)曲线,分析各指标单独或联合预测PE的价值。结果2组孕妇年龄、检测孕周、妊娠高血压史及生育史等均无差异(P>0.05)。PE组收缩压(SBP)、舒张压(DBP)、24 h尿蛋白水平、早产率、新生儿重症监护室入住率及孕前体质量指数均高于对照组(P<0.05),新生儿体质量低于对照组(P<0.05)。PE组血清PLGF/sFlt-1、3D-PDI均低于对照组,重度PE组血清PLGF/sFlt-1、3D-PDI均低于非重度PE组(均P<0.05)。PLGF与VFI呈显著正相关(P<0.01),sFlt-1与VFI呈显著负相关(P<0.01)。ROC曲线分析显示,PLGF/sFlt-1、VI、FI、VFI对PE均有预测价值,VI、FI、VFI联合预测PE的价值高于各参数指标[曲线下面积(AUC)=0.951],血清PLGF/sFlt-1、VI、FI、VFI四者联合预测价值最高(AUC=0.987)。结论PE患者孕早期血清PLGF、sFlt-1与胎盘VFI均具有显著相关性,且孕早期血清PLGF/sFlt-1及胎盘VI、FI、VFI均减低,4种指标联合应用预测PE的效能最高,可为临床早期筛查或预测PE提供参考。

超声弹性成像与彩色多普勒超声鉴别三阴性乳腺癌与纤维腺瘤的对比研究

目的:探讨超声弹性成像(UE)技术与彩色多普勒超声(CDFI)对三阴性乳腺癌(TNBC)与纤维腺瘤的鉴别诊断价值。方法:选取2021年1月至2022年1月万宁市人民医院收治并经手术病理确诊的50例TNBC患者,将其纳入TNBC组,另选取同期经手术病理证实为纤维腺瘤的50例患者纳入纤维腺瘤组。所有患者在行超声检查前均未经任何临床干预,且分别采用UE和CDFI检测,评价其病变区组织软硬程度、彩色血流及弹性评分等。以病理结果为“金标准”,分析UE和CDFI对TNBC和纤维腺瘤的诊断效能。结果:超声影像学特征显示,TNBC组多表现为病灶区域边缘毛刺征,后方回声衰减和高回声晕,且存在腋窝淋巴结转移;纤维腺瘤组多表现为病灶区域边界清晰,病灶形态规则,无微小钙化。UE检测诊断灵敏度为90.91%,特异度为82.14%,准确率为86.00%;CDFI诊断灵敏度为73.08%,特异度为75.00%,准确率为74.00%;联合检测灵敏度为94.23%,特异度为95.83%,准确率为96.00%,其检测效能高于单项检测。结论:UE鉴别诊断TNBC与纤维腺瘤的灵敏度较高,但特异度不高,与CDFI联合检测可以提高鉴别诊断特异度和准确率。

Maximum initial primary wave model for low-Froude-number reservoir landslides based on wave theory

The impulse waves induced by large-reservoir landslides can be characterized by a low Froude number.However,systematic research on predictive models specifically targeting the initial primary wave is lacking.Taking the Shuipingzi 1#landslide that occurred in the Baihetan Reservoir area of the Jinsha River in China as an engineering example,this study established a large-scale physical model(with dimensions of 30 m×29 m×3.5 m at a scale of 1:150)and conducted scaled experiments on 3D landslide-induced impulse waves.During the process in which a sliding mass displaced and compressed a body of water to generate waves,the maximum initial wave amplitude was found to be positively correlated with the sliding velocity and the volume of the landslide.With the increase in the water depth,the wave amplitude initially increased and then decreased.The duration of pressure exertion by the sliding mass at its maximum velocity directly correlated with an elevated wave amplitude.Based on the theories of low-amplitude waves and energy conservation,while considering the energy conversion efficiency,a predictive model for the initial wave amplitude was derived.This model could fit and validate the functions of wavelength and wave velocity.The accuracy of the initial wave amplitude was verified using physical experiment data,with a prediction accuracy for the maximum initial wave amplitude reaching 90%.The conversion efficiency(η)directly determined the accuracy of the estimation formula.Under clear conditions for landslide-induced impulse wave generation,estimating the value ofηthrough analogy cases was feasible.This study has derived the landslide-induced impulse waves amplitude prediction formula from the standpoints of wave theory and energy conservation,with greater consideration given to the intrinsic characteristics in the formation process of landslide-induced impulse waves,thereby enhancing the applicability and extensibility of the formula.This can facilitate the development of empirical estimation methods for landslide-induced impulse waves toward universality.

空间通信载波多普勒频偏捕获的两阶段稀疏算法

在空间通信中,信号面临远距离传输和高动态相对运动,其中,远距离传输带来很低信噪比(SNR,signal-to-noise ratio),而高动态相对运动则引起载波高动态多普勒频偏。为解决低信噪比问题,传统捕获方法需要长时间累积很多接收信号。但是,在长时间累积过程中,高动态多普勒频偏会导致严重的能量扩散问题。针对上述问题,提出了一种两阶段稀疏(TSS, two-stage-sparse)算法来捕获载波多普勒频偏。该算法首先利用粗捕获结果构造粗稀疏搜索范围,然后选择若干个较大元素来构建精稀疏搜索范围,最后搜索最大元素作为捕获结果。由于稀疏范围仅覆盖很窄的频率区间,该算法能够滤除更多的噪声干扰,从而辅助信号元素成为最大元素。理论分析和仿真结果也表明,所提TSS算法能够显著提高多普勒频偏的捕获概率。

超微血流显像技术在评估肠道克罗恩病病变活动性中的应用价值

目的:探讨超微血流显像技术(SMI)在评估肠道克罗恩病(CD)病变活动性方面的应用价值。方法:选取2022年4月-2023年8月在江门市中心医院消化内科及儿内科门诊或住院治疗确诊为克罗恩病的患者60例。根据随机数字表法将其随机分为参照组和对照组各30例。参照组患者接受SMI技术评估病变肠管肠壁的血流情况,对照组患者接受PDI技术评估病变肠管肠壁的血流情况。结果:参照组中CD病变肠管形态分级显著高于对照组(t=4.762,P<0.05),病变肠管大小显著小于参照组(t=5.192,P<0.05)。参照组肠壁血流灌注度评分和肠管完整性评分方面高于对照组(χ^(2)=4.702,3.852,P<0.05),在血流峰值速度和血流体积流量方面,参照组也高于对照组(t=4.376,5.376,P<0.05)。参照组的病变肠管活动程度(CDAI评分)和炎症程度(SES-CD评分)低于对照组(t=4.269,4.059,P<0.05)。参照组的肠道血管密度显著高于对照组(t=12.127,P<0.05)。结论:本研究结果表明,在评估肠道克罗恩病病变活动性方面,超微血流显像技术(SMI)比能量多普勒技术(PDI)更为准确和可靠,能够提供更具有临床应用价值的病变活动性评估。

三维能量多普勒血管化参数在胎儿生长受限中的预测效能分析

目的 分析探究三维能量多普勒血管化参数在胎儿生长受限(FGR)中的预测效能。方法选取2021年12月至2022年12月期间在我院进行孕检及分娩的单胎妊娠孕妇162例作为研究对象,所有孕妇均在产检时接受三维能量多普勒超声检测。根据分娩后胎儿诊断结果,将有生长受限胎儿设为FGR组(110例),将生长未受限胎儿设为对照组(52例)。对比2组胎儿临床生长指标(头围、胎盘商、胎盘体积、股骨长度、腹围、头顶径)、血管化参数[血流指数(FI)、血管化指数(VI)、血管化-血流指数(VFI)]、分析胎儿临床生长指标与血管化参数相关性,通过受试者工作特征(ROC)曲线评估血管化参数对FGR的预测效能。结果FGR组头围、胎盘商、胎盘体积、股骨长度、腹围、头顶径明显低于对照组,差异均有统计学意义(P<0.05);对照组FI、VI、VFI均显著高于FGR组,差异均有统计学意义(P<0.05);Pearson相关分析显示,FI、VI、VFI与头围、胎盘商、胎盘体积、股骨长度、腹围、头顶径均呈正相关(P均<0.05);ROC曲线分析显示,对于FGR的预测,FI、VI、VFI均有较高效能,且联合检测的ROC曲线下面积(AUC)以及灵敏度、特异度均高于各单项预测价值(P<0.05)。结论 三维能量多普勒超声检查显示血管化参数与FGR具有一定关系,血管化参数对临床预测FGR有较高的效能,有助于早期诊断并及时采取干预措施,值得临床推广应用。

三维能量多普勒血流定量技术联合常规超声对早期乳腺癌诊断价值

目的:探讨三维能量多普勒血流定量技术联合常规超声对早期乳腺癌诊断价值。方法:回顾性选取2020年12月—2022年10月仙桃市第四人民医院收治的50例早期乳腺癌患者作为早期乳腺癌组,30例癌前病变患者作为癌前病变组,另选取同期体检30例乳腺良性肿瘤患者作为良性组。三组均进行常规超声及三维能量多普勒血流定量技术检测。比较三组三维能量多普勒超声图像特征。比较三组三维能量多普勒超声血流定量参数。以病理穿刺活检为金标准,分析三维能量多普勒血流定量技术、常规超声单独检测与联合检测对早期乳腺癌的诊断价值。结果:早期乳腺癌组后方回声衰减、纵横比<1、有微钙化、边界不清晰、病灶形态不规则及血流分级2级、3级所占比例高于良性组和癌前病变组,差异有统计学意义(P<0.05)。早期乳腺癌组血管形成指数(vascularization index,VI)、血流指数(flow index,FI)、血管形成-血流指数(vascularity flow index,VFI)、彩色像素密度(color pixel density,CPD)均高于癌前病变组和良性组,癌前病变组VI、FI、VFI、CPD均高于良性组,差异有统计学意义(P<0.05)。联合检测的敏感度、准确度、阴性预测值均高于常规超声,差异有统计学意义(P<0.05)。常规超声与病理诊断的一致性一般(Kappa=0.526,P<0.05),三维能量多普勒血流定量技术、联合检测与病理诊断具有较高的一致性(Kappa=0.812、0.919,P<0.05)。结论:不同程度乳腺肿块患者其三维能量多普勒超声图像存在差异,三维能量多普勒血流定量技术联合常规超声具有较高的诊断价值。

经阴道常规超声联合三维能量多普勒超声在卵巢肿瘤鉴别诊断及预后评估中的应用研究

目的:探讨经阴道常规超声联合三维能量多普勒超声(3D-PDUS)在卵巢肿瘤鉴别诊断及预后评估中的应用价值。方法:回顾性分析2019年10月—2022年10月永城市妇幼保健院收治的104例卵巢肿瘤患者临床资料,根据病理诊断分为恶性组(33例)与良性组(71例)。比较两组患者经阴道常规超声、3D-PDUS诊断资料,探讨经阴道常规超声联合3D-PDUS在卵巢肿瘤鉴别诊断中的价值。结果:恶性组患者病灶形状不规则占比、内部回声实性/囊实性占比、有腹水占比均大于良性组,差异有统计学意义(χ^(2)=7.462、12.726、8.255,P<0.05);恶性组患者血管血流指数(VFI)、血流指数(FI)、内部血管指数(VI)高于良性组,差异有统计学意义(t=7.279、5.018、6.915,P<0.05)。logistic回归分析结果显示,经阴道常规超声征象病灶形状、内部回声、腹水和3D-PDUS参数VFI、FI、VI均与卵巢肿瘤良恶性质有关(OR>1,P<0.05);受试者工作曲线(ROC)显示,联合诊断回归模型鉴别卵巢肿瘤良恶性的曲线下面积(AUC)为0.905,有一定诊断价值。结论:经阴道常规超声征象和3D-PDUS参数均可用于鉴别卵巢肿瘤,两者联合在卵巢肿瘤鉴别诊断及预后评估中具有较高应用价值。