BACKGROUND: The accurate measurements of various data of the bone diameters of foramen ovale of living person can change the methods of puncturing trigeminal gasserian ganglion via foramen ovale for treating trifacia...BACKGROUND: The accurate measurements of various data of the bone diameters of foramen ovale of living person can change the methods of puncturing trigeminal gasserian ganglion via foramen ovale for treating trifacial neuralgia from the experience of puncture operator only to puncture by taking the objective data of measurement as the evidence, which is good for improving the accuracy of puncturing trigeminal ganglion and reducing side effects. OBJECTIVE : To observe the forms of foramen ovales in healthy adults displayed by volume rendering and multi-planar reconstruction after three-dimensional spiral CT thin-slice scan of skull base, and measure the longitudinal diameter and transverse diameter. DESIGN : A repetitive observation and measurement SETTINGS : Department of Neurosurgery and Department of Medical Imaging, Foshan Hospital of Traditional Chinese Medicine. PARTICIPANTS: Fifty healthy adults (100 sides), who were examined with three-dimensional spiral CT scan, were randomly selected from the Department of Medical Imaging, Foshan Hospital of Traditional Chinese Medicine from January 2005 to January 2006, including 26 males and 24 females, aged 25-68 years with an average of 48 years old. They were all informed and agreed with the examination. METHODS : The subjects were examined with the Philips 16-slice spiral CT-Mx 8000 IDT CT apparatus (Philips Company, Holland), the scanning ranged from 2 cm below the canthomeatal line to the level of suprasellar cistem. The width of collimator was 0.75 mm, pitch was 0.663; tube current was 350 mA, voltage was 120 kV, resolution was 512×512 matrix; slice thickness of reconstruction was 1 mm, and interval was 0.5 mm. After the three-dimensional spiral CT thin-slice scan of skull base, the image post-processing techniques including volume rendering and multi-planar reconstruction were applied to observe the forms of foramen ovales, and measure the size, longitudinal diameter and transverse diameter of the foramen ovales. The figures of the foramen ovales were drawn with mouse along the boundary of bone porous margin and soft tissue. According to the indications, the diameters were measured with computer to observe the forms of foramen ovales. MAIN OUTCOME MEASURES : The longitudinal diameter, transverse diameter and form of foramen ovales were observed. RESULTS: All the 50 healthy adults (100 sides) were involved in the analysis of results. (1) It was observed in the volume rendering images that foramen ovales had four forms of oval shape (77 sides), kidney shape (12 sides), round shape (7 sides), ribbon shape (4 sides). (2) The longitudinal diameters of left and right foramen ovales were (7.67±1.32) and (7.98±1.45) mm, and the transverse diameters were (4.04±0.83), (4.09±1.07) mm; There was no obvious difference between left and right longitudinal diameters (t = 1.63, P = 0.11 ), and left and right transverse diameters were close (t = 0.45, P= 0.65). CONCLUSION : The non-invasive techniques of volume rendering and multi-planar reconstruction after three-dimensional spiral CT thin-slice scan can clearly display the formand size of foramen ovale in healthy adults.展开更多
In order to improve the diagnosis and analysis ability of 3D spiral CT and to reconstruct the contour of 3D spiral CT damage image,a contour reconstruction method based on sharpening template enhancement for 3D spiral...In order to improve the diagnosis and analysis ability of 3D spiral CT and to reconstruct the contour of 3D spiral CT damage image,a contour reconstruction method based on sharpening template enhancement for 3D spiral CT damage image is proposed.This method uses the active contour LasSO model to extract the contour feature of the 3D spiral CT damage image and enhances the information by sharpening the template en.hancement technique and makes the noise separation of the 3D spiral CT damage image.The spiral CT image was procesed with ENT,and the statistical shape model of 3D spiral CT damage image was established.The.gradient algorithm is used to decompose the feature to realize the analysis and reconstruction of the contour feature of the 3D spiral CT damage image,so as to improve the adaptive feature matching ability and the ability to locate the abnormal feature points.The simulation results show that in the 3D spiral CT damage image contour reconstruction,the proposed method performs well in the feature matching of the output pixels,shortens the contour reconstruction time by 20/ms,and provides a strong ability to express the image information.The normalized reconstruction error of CES is 30%,which improves the recognition ability of 3D spiral CT damage image,and increases the signal-to noise ratio of peak output by 40 dB over other methods.展开更多
目的基于Markov模型评价肺结节低剂量螺旋CT(LDCT)筛查的卫生经济学。方法利用2021年—2023年北京市某三甲医院的肺结节LDCT筛查数据和部分国外临床研究数据,采用成本效用分析方法,通过增量成本效用比(ICUR)确定优势筛查策略;使用R语言...目的基于Markov模型评价肺结节低剂量螺旋CT(LDCT)筛查的卫生经济学。方法利用2021年—2023年北京市某三甲医院的肺结节LDCT筛查数据和部分国外临床研究数据,采用成本效用分析方法,通过增量成本效用比(ICUR)确定优势筛查策略;使用R语言获得转移概率参数,利用TreeAge Pro 2011软件构建Markov模型。假设以我国10万名55岁及以上人群为肺结节筛查对象,模拟其疾病发展情况,并通过敏感性分析评价该模型的稳定性。结果成本效用分析显示,该模型经20次循环后,LDCT筛查策略的总成本为3543088618元,相较于不筛查策略的总成本增加了784130651元,额外获得了7996个质量调整生命年(QALY),每获得一个QALY需多花费98059.77元。采用WHO卫生经济学评价标准,LDCT筛查策略的ICUR大于1倍人均国内生产总值(GDP)但小于3倍人均GDP,为优势策略。敏感性分析显示,各变量在其敏感性分析范围内无论如何变化,都不会对ICUR产生较大影响,表明该模型具有较好的稳定性。结论在55岁及以上人群中开展每年一次肺结节LDCT筛查的ICUR小于3倍人均GDP,具有一定的经济学效用,该筛查策略有利于肺癌的“早发现、早诊断、早治疗”。展开更多
基金a grant fromTackle Key Problems in Sci-ence and Technology of FoshanCity, No. 200505075
文摘BACKGROUND: The accurate measurements of various data of the bone diameters of foramen ovale of living person can change the methods of puncturing trigeminal gasserian ganglion via foramen ovale for treating trifacial neuralgia from the experience of puncture operator only to puncture by taking the objective data of measurement as the evidence, which is good for improving the accuracy of puncturing trigeminal ganglion and reducing side effects. OBJECTIVE : To observe the forms of foramen ovales in healthy adults displayed by volume rendering and multi-planar reconstruction after three-dimensional spiral CT thin-slice scan of skull base, and measure the longitudinal diameter and transverse diameter. DESIGN : A repetitive observation and measurement SETTINGS : Department of Neurosurgery and Department of Medical Imaging, Foshan Hospital of Traditional Chinese Medicine. PARTICIPANTS: Fifty healthy adults (100 sides), who were examined with three-dimensional spiral CT scan, were randomly selected from the Department of Medical Imaging, Foshan Hospital of Traditional Chinese Medicine from January 2005 to January 2006, including 26 males and 24 females, aged 25-68 years with an average of 48 years old. They were all informed and agreed with the examination. METHODS : The subjects were examined with the Philips 16-slice spiral CT-Mx 8000 IDT CT apparatus (Philips Company, Holland), the scanning ranged from 2 cm below the canthomeatal line to the level of suprasellar cistem. The width of collimator was 0.75 mm, pitch was 0.663; tube current was 350 mA, voltage was 120 kV, resolution was 512×512 matrix; slice thickness of reconstruction was 1 mm, and interval was 0.5 mm. After the three-dimensional spiral CT thin-slice scan of skull base, the image post-processing techniques including volume rendering and multi-planar reconstruction were applied to observe the forms of foramen ovales, and measure the size, longitudinal diameter and transverse diameter of the foramen ovales. The figures of the foramen ovales were drawn with mouse along the boundary of bone porous margin and soft tissue. According to the indications, the diameters were measured with computer to observe the forms of foramen ovales. MAIN OUTCOME MEASURES : The longitudinal diameter, transverse diameter and form of foramen ovales were observed. RESULTS: All the 50 healthy adults (100 sides) were involved in the analysis of results. (1) It was observed in the volume rendering images that foramen ovales had four forms of oval shape (77 sides), kidney shape (12 sides), round shape (7 sides), ribbon shape (4 sides). (2) The longitudinal diameters of left and right foramen ovales were (7.67±1.32) and (7.98±1.45) mm, and the transverse diameters were (4.04±0.83), (4.09±1.07) mm; There was no obvious difference between left and right longitudinal diameters (t = 1.63, P = 0.11 ), and left and right transverse diameters were close (t = 0.45, P= 0.65). CONCLUSION : The non-invasive techniques of volume rendering and multi-planar reconstruction after three-dimensional spiral CT thin-slice scan can clearly display the formand size of foramen ovale in healthy adults.
文摘In order to improve the diagnosis and analysis ability of 3D spiral CT and to reconstruct the contour of 3D spiral CT damage image,a contour reconstruction method based on sharpening template enhancement for 3D spiral CT damage image is proposed.This method uses the active contour LasSO model to extract the contour feature of the 3D spiral CT damage image and enhances the information by sharpening the template en.hancement technique and makes the noise separation of the 3D spiral CT damage image.The spiral CT image was procesed with ENT,and the statistical shape model of 3D spiral CT damage image was established.The.gradient algorithm is used to decompose the feature to realize the analysis and reconstruction of the contour feature of the 3D spiral CT damage image,so as to improve the adaptive feature matching ability and the ability to locate the abnormal feature points.The simulation results show that in the 3D spiral CT damage image contour reconstruction,the proposed method performs well in the feature matching of the output pixels,shortens the contour reconstruction time by 20/ms,and provides a strong ability to express the image information.The normalized reconstruction error of CES is 30%,which improves the recognition ability of 3D spiral CT damage image,and increases the signal-to noise ratio of peak output by 40 dB over other methods.
文摘目的基于Markov模型评价肺结节低剂量螺旋CT(LDCT)筛查的卫生经济学。方法利用2021年—2023年北京市某三甲医院的肺结节LDCT筛查数据和部分国外临床研究数据,采用成本效用分析方法,通过增量成本效用比(ICUR)确定优势筛查策略;使用R语言获得转移概率参数,利用TreeAge Pro 2011软件构建Markov模型。假设以我国10万名55岁及以上人群为肺结节筛查对象,模拟其疾病发展情况,并通过敏感性分析评价该模型的稳定性。结果成本效用分析显示,该模型经20次循环后,LDCT筛查策略的总成本为3543088618元,相较于不筛查策略的总成本增加了784130651元,额外获得了7996个质量调整生命年(QALY),每获得一个QALY需多花费98059.77元。采用WHO卫生经济学评价标准,LDCT筛查策略的ICUR大于1倍人均国内生产总值(GDP)但小于3倍人均GDP,为优势策略。敏感性分析显示,各变量在其敏感性分析范围内无论如何变化,都不会对ICUR产生较大影响,表明该模型具有较好的稳定性。结论在55岁及以上人群中开展每年一次肺结节LDCT筛查的ICUR小于3倍人均GDP,具有一定的经济学效用,该筛查策略有利于肺癌的“早发现、早诊断、早治疗”。