目的分析基于超声乳腺影像报告和数据系统(Breast Imaging Reporting and Data System,BI-RADS)分类对不同病理类型乳腺肿块诊断的结果。方法方便选取2022年3月—2023年8月在枣庄市台儿庄区人民医院和济南市平阴县中医医院进行检查的74...目的分析基于超声乳腺影像报告和数据系统(Breast Imaging Reporting and Data System,BI-RADS)分类对不同病理类型乳腺肿块诊断的结果。方法方便选取2022年3月—2023年8月在枣庄市台儿庄区人民医院和济南市平阴县中医医院进行检查的74例女性患者为研究对象。以病理检查为金标准,经病理证实乳腺肿块共80个,采用kappa检验分析超声检查与病理结果的一致性。结果病理结果显示,良性肿块61个,恶性肿块19个(kappa值为0.710,P<0.01)。超声BI-RADS分类诊断的灵敏度、特异度、准确度分别为96.72%、84.21%、93.75%。超声BI-RADS对良性肿瘤的诊断符合率均≥85.71%,而对恶性肿瘤诊断中,符合率最低时为75.00%。结论虽然不同病理类型乳腺肿块的超声诊断符合率较高,但在实际操作过程中仍然存在漏诊误诊等情况,故需要临床医师了解超声检查的不足,对超声诊断质量做好把控。展开更多
Background Accurate evaluation of response following chemotherapy treatment is essential for surgical decision making in patients with breast cancer. Modalities that have been used to monitor response to neo-adjuvant ...Background Accurate evaluation of response following chemotherapy treatment is essential for surgical decision making in patients with breast cancer. Modalities that have been used to monitor response to neo-adjuvant chemotherapy （NAC） include physical examination （PE）, ultrasound （US）, and magnetic resonance imaging （MRI）. The purpose of this study was to evaluate the accuracy of PE, US, and MRI in predicting the response to NAC in patients with breast cancer. Methods According to the response evaluation criteria in solid tumors guidelines, the largest unidimensional measurement of the tumor diameter evaluated by PE, US, and MRI before and after NAC was classified into four grades, including clinical complete response, clinical partial response, clinical progressive disease, clinical stable disease, and compared with the final histopathological examination. Results Of the 64 patients who received NAC, the pathologic complete response （pCR） was shown in 13 of 64 patients （20%）. The sensitivity of PE, US, and MRI in predicting the major pathologic response was 73%, 75%, and 80%, respectively, and the specificity was 45%, 50%, and 50% respectively. For predicting a pCR, the sensitivity of PE, US, and MRI was 46%, 46%, and 39%, respectively, and the specificity was 65%, 98%, and 92% respectively. Conclusions Compared with final pathologic findings, all these three clinical and imaging modalities tended to obviously underestimate the pCR rate. A more appropriate, universal, and practical standard by clinical and imaging modalities in predicting the response to neo-adjuvant chemotherapy in vivo is essential.展开更多
BACKGROUND Sweat glands belong to skin appendages.Sweat gland tumors are uncommon,especially when they occur as malignant tumors in the breast.We report a case of malignant sweat gland tumor of the breast,including im...BACKGROUND Sweat glands belong to skin appendages.Sweat gland tumors are uncommon,especially when they occur as malignant tumors in the breast.We report a case of malignant sweat gland tumor of the breast,including imaging and pathological findings.CASE SUMMARY A 47-year-old woman visited our hospital with a non-tender palpable lesion in her left breast.The lesion had not shown changes for 10 years.However,it recently increased in size.Sonography showed a well circumscribed cystic lesion with internal debris and fluid-fluid level.Magnetic resonance imaging showed a well circumscribed oval mass with T1 hyper-intensity compared to muscle and T2 high signal intensity.There was a small enhancing mural component in the inner wall of the mass.The tumor was resected.Its pathologic result was a malignant transformation of benign sweat gland tumor such as hidradenoma.The lesion was treated with excision and radiation therapy.At 1-year follow up,there was no local recurrence or metastasis in the patient.CONCLUSION In the case of a rapid growing cystic mass in the nipple and subareola,it is necessary to distinguish it from a malignant sweat gland tumor.展开更多
文摘目的分析基于超声乳腺影像报告和数据系统(Breast Imaging Reporting and Data System,BI-RADS)分类对不同病理类型乳腺肿块诊断的结果。方法方便选取2022年3月—2023年8月在枣庄市台儿庄区人民医院和济南市平阴县中医医院进行检查的74例女性患者为研究对象。以病理检查为金标准,经病理证实乳腺肿块共80个,采用kappa检验分析超声检查与病理结果的一致性。结果病理结果显示,良性肿块61个,恶性肿块19个(kappa值为0.710,P<0.01)。超声BI-RADS分类诊断的灵敏度、特异度、准确度分别为96.72%、84.21%、93.75%。超声BI-RADS对良性肿瘤的诊断符合率均≥85.71%,而对恶性肿瘤诊断中,符合率最低时为75.00%。结论虽然不同病理类型乳腺肿块的超声诊断符合率较高,但在实际操作过程中仍然存在漏诊误诊等情况,故需要临床医师了解超声检查的不足,对超声诊断质量做好把控。
文摘Background Accurate evaluation of response following chemotherapy treatment is essential for surgical decision making in patients with breast cancer. Modalities that have been used to monitor response to neo-adjuvant chemotherapy （NAC） include physical examination （PE）, ultrasound （US）, and magnetic resonance imaging （MRI）. The purpose of this study was to evaluate the accuracy of PE, US, and MRI in predicting the response to NAC in patients with breast cancer. Methods According to the response evaluation criteria in solid tumors guidelines, the largest unidimensional measurement of the tumor diameter evaluated by PE, US, and MRI before and after NAC was classified into four grades, including clinical complete response, clinical partial response, clinical progressive disease, clinical stable disease, and compared with the final histopathological examination. Results Of the 64 patients who received NAC, the pathologic complete response （pCR） was shown in 13 of 64 patients （20%）. The sensitivity of PE, US, and MRI in predicting the major pathologic response was 73%, 75%, and 80%, respectively, and the specificity was 45%, 50%, and 50% respectively. For predicting a pCR, the sensitivity of PE, US, and MRI was 46%, 46%, and 39%, respectively, and the specificity was 65%, 98%, and 92% respectively. Conclusions Compared with final pathologic findings, all these three clinical and imaging modalities tended to obviously underestimate the pCR rate. A more appropriate, universal, and practical standard by clinical and imaging modalities in predicting the response to neo-adjuvant chemotherapy in vivo is essential.
文摘BACKGROUND Sweat glands belong to skin appendages.Sweat gland tumors are uncommon,especially when they occur as malignant tumors in the breast.We report a case of malignant sweat gland tumor of the breast,including imaging and pathological findings.CASE SUMMARY A 47-year-old woman visited our hospital with a non-tender palpable lesion in her left breast.The lesion had not shown changes for 10 years.However,it recently increased in size.Sonography showed a well circumscribed cystic lesion with internal debris and fluid-fluid level.Magnetic resonance imaging showed a well circumscribed oval mass with T1 hyper-intensity compared to muscle and T2 high signal intensity.There was a small enhancing mural component in the inner wall of the mass.The tumor was resected.Its pathologic result was a malignant transformation of benign sweat gland tumor such as hidradenoma.The lesion was treated with excision and radiation therapy.At 1-year follow up,there was no local recurrence or metastasis in the patient.CONCLUSION In the case of a rapid growing cystic mass in the nipple and subareola,it is necessary to distinguish it from a malignant sweat gland tumor.
