Comparison of the body pain and trauma degree between uni-portal and three-portal video-assisted thoracoscopic surgery for the treatment of lung cancer

Objective:To study the differences in the body pain and trauma degree between uniportal and three-portal video-assisted thoracoscopic surgery for the treatment of lung cancer.Methods:A total of 108 patients with non-small cell lung cancer who received radical operation in our hospital between February 2013 and February 2016 were selected and divided into the uniportal group (n=52) who received uniportal video-assisted thoracoscopic surgery and the three-portal group (n=56) who received three-portal video-assisted thoracoscopic surgery after the operation methods and related laboratory results were reviewed. Before operation and 24 h after operation, the differences in serum levels of pain mediators, oxidative stress indexes and inflammation indexes were compared between the two groups of patients.Results: Before operation, the differences in serum levels of pain mediators, oxidative stress indexes and inflammation indexes were not statistically significant between the two groups of patients. 24 h after operation, serum pain mediators NE, DA and 5-HT levels of observation group were lower than those of control group;oxidative stress indexes MDA and O2- levels were lower than those of control group while SOD and GSH-Px levels were higher than those of control group;inflammation indexes IL-6, IL-8, CRP and TNF-α levels were lower than those of control group.Conclusion: Uniportal video-assisted thoracoscopic surgery for the treatment of lung cancer causes less surgery trauma, and patients' postoperative pain and systemic inflammatory stress response are lighter.

自发性气胸患者应用单孔胸腔镜肺大疱切除术的治疗效果观察

目的探究单孔胸腔镜肺大疱切除术在自发性气胸患者中的治疗效果。方法回顾性分析2020年1月至2023年6月期间成都大学附属医院收治的94例自发性气胸患者,按照治疗方式不同将其分为A组(50例)与B组(44例)。A组行单孔胸腔镜下肺大刨切除术,B组行双孔胸腔镜下肺大疱切除术。对比2组手术指标,术后12、24、48、72 h疼痛情况,术前与术后1周血清指标、血气指标、术后并发症及术后6个月复发情况。结果A组手术时长高于B组,术中出血量、置管时长、胸腔引流量及住院时长均短于B组;术后12、24、48 h时,2组视觉模拟评分量表(VAS)评分均呈现降低趋势,且A组术后24 h和48 h VAS评分均低于B组;术后1周,2组TGF-β1、IL-1β、FGF-10、PaCO_(2)水平均降低,且A组均低于B组(P<0.05);术后1周,2组PaO_(2)均升高,且A组高于B组(P<0.05);2组并发症比较(8%和16%)差异无统计学意义(P>0.05);术后随访6个月,2组总复发率比较(2%与7%)差异无统计学意义(P>0.05)。结论相较于双孔胸腔镜技术,单孔胸腔镜肺大疱切除术用于自发性气胸治疗更具优势,可减少术中出血量,降低术后疼痛程度,改善炎症反应与血气状态,安全可靠。

单孔胸腔镜肺大疱切除术治疗老年自发性气胸合并肺大疱的效果

目的:观察单孔胸腔镜肺大疱切除术治疗老年自发性气胸合并肺大疱的效果。方法:选取2016年8月—2023年8月张掖市甘州区人民医院收治的老年自发性气胸合并肺大疱患者60例作为研究对象,使用随机数字法分为观察组与对照组,各30例。对照组行三孔胸腔镜肺大疱切除术,观察组行单孔胸腔镜肺大疱切除术。比较两组围术期指标、肺功能、术后并发症发生情况。结果:观察组引流管留置时间、术后住院时间短于对照组,差异有统计学意义(P<0.001);术后,两组第1秒用力呼气容积占预计值的百分比、肺总量、肺残气量升高,观察组高于对照组,差异有统计学意义(P<0.05);观察组术后并发症发生率低于对照组,差异有统计学意义(P=0.028)。结论:单孔胸腔镜肺大疱切除术治疗老年自发性气胸合并肺大疱的效果显著,可加速术后恢复,改善肺功能,降低术后并发症发生率。