<strong>Objectives:</strong> In many articles, gastroesophageal reflux has been identified as a strong underlying factor in laryngeal and extra-laryngeal disorders. But the exact mechanism of these complic...<strong>Objectives:</strong> In many articles, gastroesophageal reflux has been identified as a strong underlying factor in laryngeal and extra-laryngeal disorders. But the exact mechanism of these complications is still controversial. The present study was designed to investigate the association of gastroesophageal acid reflux to ear, nose and throat diseases in children. <strong>Materials and Methods:</strong> The present study is a descriptive cross-sectional study and its statistical population includes children with gastroesophageal reflux disease over a period of 18 months visited Salmaniya Medical Complex, Kingdom of Bahrain. The diagnosis of GERD (Gastroesophageal reflux disease) was recorded based on symptoms, radiological and endoscopic findings and ESPGHAN guidelines. The ear, nose and throat were examined and problems recorded followed by initiation of medical treatment. After one and six months of follow up post treatment all clinical findings were recorded. <strong>Results:</strong> 26.4% of the children were under one year old. In 78% of children, a family history of GERD was reported to be negative. Cough was the most common clinical complaint. After one month of treatment, 15% of gastrointestinal symptoms and 40% of ENT symptoms completely improved. After six months of treatment 72% percentage of gastrointestinal symptoms and ENT symptoms completely improved. <strong>Conclusion:</strong> This study showed that gastroesophageal reflux disease should be considered, diagnosed and treated in all children with refractory ear, nose and throat symptoms.展开更多
目的:探讨奥美拉唑联合四君子汤治疗咽喉反流的临床疗效。方法:经反流症状指数量表(The recux find ing Score.RSI)和反流检查计分量表(The reflux fingd ing score,RFS)诊断为咽喉反流的72例患者,随机分为观察组和对照组。观察组应用...目的:探讨奥美拉唑联合四君子汤治疗咽喉反流的临床疗效。方法:经反流症状指数量表(The recux find ing Score.RSI)和反流检查计分量表(The reflux fingd ing score,RFS)诊断为咽喉反流的72例患者,随机分为观察组和对照组。观察组应用奥美拉唑联合四君子汤治疗,对照组应用奥美拉唑和胃动力药物治疗,以4周为一疗程,治疗结束后进行临床疗效对比。结果:观察组38例,总有效率92.11(35/38例);对照组34例,总有效率52.94%(16/34例),两组差异有统计学意义(p<0.05)。结论:奥美拉唑联合四君子汤可有效缓解症状,疗效优于单纯奥美拉唑和胃动力药物治疗。展开更多
文摘<strong>Objectives:</strong> In many articles, gastroesophageal reflux has been identified as a strong underlying factor in laryngeal and extra-laryngeal disorders. But the exact mechanism of these complications is still controversial. The present study was designed to investigate the association of gastroesophageal acid reflux to ear, nose and throat diseases in children. <strong>Materials and Methods:</strong> The present study is a descriptive cross-sectional study and its statistical population includes children with gastroesophageal reflux disease over a period of 18 months visited Salmaniya Medical Complex, Kingdom of Bahrain. The diagnosis of GERD (Gastroesophageal reflux disease) was recorded based on symptoms, radiological and endoscopic findings and ESPGHAN guidelines. The ear, nose and throat were examined and problems recorded followed by initiation of medical treatment. After one and six months of follow up post treatment all clinical findings were recorded. <strong>Results:</strong> 26.4% of the children were under one year old. In 78% of children, a family history of GERD was reported to be negative. Cough was the most common clinical complaint. After one month of treatment, 15% of gastrointestinal symptoms and 40% of ENT symptoms completely improved. After six months of treatment 72% percentage of gastrointestinal symptoms and ENT symptoms completely improved. <strong>Conclusion:</strong> This study showed that gastroesophageal reflux disease should be considered, diagnosed and treated in all children with refractory ear, nose and throat symptoms.
文摘目的:探讨奥美拉唑联合四君子汤治疗咽喉反流的临床疗效。方法:经反流症状指数量表(The recux find ing Score.RSI)和反流检查计分量表(The reflux fingd ing score,RFS)诊断为咽喉反流的72例患者,随机分为观察组和对照组。观察组应用奥美拉唑联合四君子汤治疗,对照组应用奥美拉唑和胃动力药物治疗,以4周为一疗程,治疗结束后进行临床疗效对比。结果:观察组38例,总有效率92.11(35/38例);对照组34例,总有效率52.94%(16/34例),两组差异有统计学意义(p<0.05)。结论:奥美拉唑联合四君子汤可有效缓解症状,疗效优于单纯奥美拉唑和胃动力药物治疗。
