目的探讨六味地黄汤加减对肝肾阴虚型2型糖尿病绝经后女性患者骨密度影响。方法选取某院2022年5月~2023年5月收治的204例肝肾阴虚型2型糖尿病绝经后女性患者,随机分为两组。对照组102例使用常规控制血糖及补钙对症治疗,观察组102例患者...目的探讨六味地黄汤加减对肝肾阴虚型2型糖尿病绝经后女性患者骨密度影响。方法选取某院2022年5月~2023年5月收治的204例肝肾阴虚型2型糖尿病绝经后女性患者,随机分为两组。对照组102例使用常规控制血糖及补钙对症治疗,观察组102例患者在对照组基础上联合使用六味地黄汤加减治疗。两组患者均治疗6个月。比较两组患者治疗前后血糖情况[糖化血红蛋白(glycosylated hemoglobin,HbA1c)、空腹血糖(fasting plasma glucose,FPG)]、腰椎L2~4及左侧股骨颈骨密度(bone mineral density,BMD)、骨代谢标志物[总型胶原氨基酸延长肽(Total type I collagen amino terminal lengthening peptide,PINP)、β-胶原特殊序列(β-Crosslaps,β-CTX)]、中医证候积分。结果两组患者入院时血糖情况、腰椎及股骨颈骨密度、骨代谢标志物及中医证候积分差异无统计学意义(P>0.05)。治疗后,两组患者各指标均有好转(P<0.05),观察组患者HbA1c、FPG、PINP、β-CTX水平、中医证候积分较低(P<0.05),腰椎L2~4及左侧股骨颈骨BMD值较高(P<0.05)。结论肝肾阴虚型2型糖尿病绝经后女性患者使用常规治疗联合六味地黄汤加减可改善患者中医证型积分,有效控制患者血糖控制情况,提升患者骨密度,改善骨代谢标志物水平。展开更多
With the popularization of clinical ultrasound technology,small follicular ovulation infertility is gradually being recognized in clinical practice.Low follicle ovulation refers to the phenomenon that the average valu...With the popularization of clinical ultrasound technology,small follicular ovulation infertility is gradually being recognized in clinical practice.Low follicle ovulation refers to the phenomenon that the average value of the three diameter lines of the dominant follicle is less than 14mm-18mm under continuous ultrasound monitoring.The dominant follicle ovulates before it develops to maturity,which is a kind of ovulation disorder and one of the leading causes of unexplained infertility[1],accounting for 25%-30%of the total number of patients with infertility[2].At present,Western medicine mostly uses ovulation,stimulating drugs to treat this disease.Still,due to the clinical result of“high ovulation but low pregnancy”,there are certain obstacles in treatment.The purpose of this article is to discuss Zhang Xiaofeng’s understanding of TCM of this disease.The tutor believes that the location of the disease is in the kidney,and the mechanism of the disease is kidney yin deficiency and blood heat.The treatment principle is sequential therapy,nourishing yin and clearing heat,taking into account the protection of the spleen and stomach,and the therapeutic effect is perfect.展开更多
目的通过文献研究,分析原发性开角型青光眼(primary open angle glaucoma,POAG)证型分布特点及其证候、证素特点,为临床POAG的诊治提供依据。方法检索CNKI(中国知网数据库)、VIP(维普数据库)、CBM(中国生物医学文献数据库)和Wanfang数据...目的通过文献研究,分析原发性开角型青光眼(primary open angle glaucoma,POAG)证型分布特点及其证候、证素特点,为临床POAG的诊治提供依据。方法检索CNKI(中国知网数据库)、VIP(维普数据库)、CBM(中国生物医学文献数据库)和Wanfang数据库(万方数据库),采用EpiData3.1软件建立POAG证候文献数据库,应用统计软件SPSS 19.0进行统计分析。结果最终纳入文献11篇,包括644例不同证型的患者,规范后的POAG证型11种,最常见的4种证型为:肝肾亏虚证(26.55%)、肝郁化火证(23.45%)、痰湿泛目证(18.94%)、肝郁气滞证(13.20%),与POAG相关的病位证素为肝,病性证素主要与阴虚、血虚、阳亢、气滞相关。结论本研究初步反映了POAG常见证型、证候分布特点,并对其证素特点进行了概括,为临床POAG的诊疗提供依据。展开更多
文摘目的探讨六味地黄汤加减对肝肾阴虚型2型糖尿病绝经后女性患者骨密度影响。方法选取某院2022年5月~2023年5月收治的204例肝肾阴虚型2型糖尿病绝经后女性患者,随机分为两组。对照组102例使用常规控制血糖及补钙对症治疗,观察组102例患者在对照组基础上联合使用六味地黄汤加减治疗。两组患者均治疗6个月。比较两组患者治疗前后血糖情况[糖化血红蛋白(glycosylated hemoglobin,HbA1c)、空腹血糖(fasting plasma glucose,FPG)]、腰椎L2~4及左侧股骨颈骨密度(bone mineral density,BMD)、骨代谢标志物[总型胶原氨基酸延长肽(Total type I collagen amino terminal lengthening peptide,PINP)、β-胶原特殊序列(β-Crosslaps,β-CTX)]、中医证候积分。结果两组患者入院时血糖情况、腰椎及股骨颈骨密度、骨代谢标志物及中医证候积分差异无统计学意义(P>0.05)。治疗后,两组患者各指标均有好转(P<0.05),观察组患者HbA1c、FPG、PINP、β-CTX水平、中医证候积分较低(P<0.05),腰椎L2~4及左侧股骨颈骨BMD值较高(P<0.05)。结论肝肾阴虚型2型糖尿病绝经后女性患者使用常规治疗联合六味地黄汤加减可改善患者中医证型积分,有效控制患者血糖控制情况,提升患者骨密度,改善骨代谢标志物水平。
文摘With the popularization of clinical ultrasound technology,small follicular ovulation infertility is gradually being recognized in clinical practice.Low follicle ovulation refers to the phenomenon that the average value of the three diameter lines of the dominant follicle is less than 14mm-18mm under continuous ultrasound monitoring.The dominant follicle ovulates before it develops to maturity,which is a kind of ovulation disorder and one of the leading causes of unexplained infertility[1],accounting for 25%-30%of the total number of patients with infertility[2].At present,Western medicine mostly uses ovulation,stimulating drugs to treat this disease.Still,due to the clinical result of“high ovulation but low pregnancy”,there are certain obstacles in treatment.The purpose of this article is to discuss Zhang Xiaofeng’s understanding of TCM of this disease.The tutor believes that the location of the disease is in the kidney,and the mechanism of the disease is kidney yin deficiency and blood heat.The treatment principle is sequential therapy,nourishing yin and clearing heat,taking into account the protection of the spleen and stomach,and the therapeutic effect is perfect.
文摘目的通过文献研究,分析原发性开角型青光眼(primary open angle glaucoma,POAG)证型分布特点及其证候、证素特点,为临床POAG的诊治提供依据。方法检索CNKI(中国知网数据库)、VIP(维普数据库)、CBM(中国生物医学文献数据库)和Wanfang数据库(万方数据库),采用EpiData3.1软件建立POAG证候文献数据库,应用统计软件SPSS 19.0进行统计分析。结果最终纳入文献11篇,包括644例不同证型的患者,规范后的POAG证型11种,最常见的4种证型为:肝肾亏虚证(26.55%)、肝郁化火证(23.45%)、痰湿泛目证(18.94%)、肝郁气滞证(13.20%),与POAG相关的病位证素为肝,病性证素主要与阴虚、血虚、阳亢、气滞相关。结论本研究初步反映了POAG常见证型、证候分布特点,并对其证素特点进行了概括,为临床POAG的诊疗提供依据。
