研究了射频磁控溅射法制备的HA/Ti6Al4V复合材料种植体在模拟体液(Simulated body fluid,SBF)环境下的生物活性。利用扫描电镜(SEM)、能谱分析(EDS)、红外光谱(FTIR)及X-射线衍射(XRD)分析了该种植体涂层在模拟体液中浸泡前后的表面形...研究了射频磁控溅射法制备的HA/Ti6Al4V复合材料种植体在模拟体液(Simulated body fluid,SBF)环境下的生物活性。利用扫描电镜(SEM)、能谱分析(EDS)、红外光谱(FTIR)及X-射线衍射(XRD)分析了该种植体涂层在模拟体液中浸泡前后的表面形貌、界面结合状态、晶体结构和相组成的变化,结果表明:该种植体涂层在模拟体液中存在溶解和新生物质在其表面沉积相伴的过程。其中,HA涂层表面的新生物质是一种缺钙型且含有CO32-的类骨磷灰石,其n(Ca)/n(P)比值约为1.56,晶粒小,结晶度低,接近于非晶态,这与自然骨中无机相的结构成分相似,因此具有良好生物相容性和生物活性。展开更多
用化学沉淀法制备β-磷酸钙/羟基磷灰石双向陶瓷(β-TCP/HA)粉末。采用粉末冶金法,以(HA/β-TCP)粉末和Ti粉末为原料,经1050℃真空烧结60 min制备出含不同质量分数钛粉的(HA/β-TCP)/Ti复合材料:(β-TCP/HA)/60wt%Ti、(β-TCP/HA)/70wt...用化学沉淀法制备β-磷酸钙/羟基磷灰石双向陶瓷(β-TCP/HA)粉末。采用粉末冶金法,以(HA/β-TCP)粉末和Ti粉末为原料,经1050℃真空烧结60 min制备出含不同质量分数钛粉的(HA/β-TCP)/Ti复合材料:(β-TCP/HA)/60wt%Ti、(β-TCP/HA)/70wt%Ti、(β-TCP/HA)/80wt%Ti。用扫描电子显微镜(SEM)和X射线衍射仪(XRD)对复合材料进行了组织结构和物相成分表征,并采用维氏显微硬度计测试了复合材料的显微硬度。采用模拟体液浸泡(SPF)进行体外生物活性表征,结果表明:复合材料的物相主要为α-Ti、TiO_2、Ca5(PO4)3(OH)、β-Ca3(PO4)2和Ca Ti O3;块状陶瓷相沿富Ti相等形成的网状结构的孔隙中分布。(β-TCP/HA)/60wt%Ti复合材料中Ca5(PO4)3(OH)分解程度最小,显微硬度为HV539,最接近人体骨骼的硬度。经14天SPF溶液浸泡后,Ca5(PO4)3(OH)的衍射峰沿(211)晶面具有明显的择优取向,材料表面密布结晶度良好的棒状Ca5(PO4)3(OH)晶体。展开更多
This work aims at developing a new and reliable biomaterial for implant application by fabricating calcium phosphate/Al2O3 biocomposite coating on medical titanium using a hybrid technique of anodic oxidation and hydr...This work aims at developing a new and reliable biomaterial for implant application by fabricating calcium phosphate/Al2O3 biocomposite coating on medical titanium using a hybrid technique of anodic oxidation and hydrothermal treatment. The pre- and post-anodized samples were investigated by scanning electron microscopy (SEM), energy dispersive analysis of X-ray (EDAX), transmission electron microscopy (TEM), and X-ray diffraction (XRD) techniques. The results indicated that porous anodic alumina film containing Ca and P was obtained on the as-prepared Al-Ti substrate through anodization, and the subsequent hydrothermal treatment led to the formation of calcium phosphate crystals. SEM and TEM results showed that calcium phosphate crystals were in nanometer, in-situ embedded in the walls of the cylindrical structure of anodic alumina, and finally formed a thin and porous top layer on the anodic alumina layer. The nanometer effect of calcium phosphate top layer, the porous and cylindrical microstructure of calcium phosphate/Al2O3-Ti, and the in-situ growth effect are expect to possess a very good combination of bioactivity and mechanical integrity.展开更多
文摘研究了射频磁控溅射法制备的HA/Ti6Al4V复合材料种植体在模拟体液(Simulated body fluid,SBF)环境下的生物活性。利用扫描电镜(SEM)、能谱分析(EDS)、红外光谱(FTIR)及X-射线衍射(XRD)分析了该种植体涂层在模拟体液中浸泡前后的表面形貌、界面结合状态、晶体结构和相组成的变化,结果表明:该种植体涂层在模拟体液中存在溶解和新生物质在其表面沉积相伴的过程。其中,HA涂层表面的新生物质是一种缺钙型且含有CO32-的类骨磷灰石,其n(Ca)/n(P)比值约为1.56,晶粒小,结晶度低,接近于非晶态,这与自然骨中无机相的结构成分相似,因此具有良好生物相容性和生物活性。
文摘用化学沉淀法制备β-磷酸钙/羟基磷灰石双向陶瓷(β-TCP/HA)粉末。采用粉末冶金法,以(HA/β-TCP)粉末和Ti粉末为原料,经1050℃真空烧结60 min制备出含不同质量分数钛粉的(HA/β-TCP)/Ti复合材料:(β-TCP/HA)/60wt%Ti、(β-TCP/HA)/70wt%Ti、(β-TCP/HA)/80wt%Ti。用扫描电子显微镜(SEM)和X射线衍射仪(XRD)对复合材料进行了组织结构和物相成分表征,并采用维氏显微硬度计测试了复合材料的显微硬度。采用模拟体液浸泡(SPF)进行体外生物活性表征,结果表明:复合材料的物相主要为α-Ti、TiO_2、Ca5(PO4)3(OH)、β-Ca3(PO4)2和Ca Ti O3;块状陶瓷相沿富Ti相等形成的网状结构的孔隙中分布。(β-TCP/HA)/60wt%Ti复合材料中Ca5(PO4)3(OH)分解程度最小,显微硬度为HV539,最接近人体骨骼的硬度。经14天SPF溶液浸泡后,Ca5(PO4)3(OH)的衍射峰沿(211)晶面具有明显的择优取向,材料表面密布结晶度良好的棒状Ca5(PO4)3(OH)晶体。
文摘This work aims at developing a new and reliable biomaterial for implant application by fabricating calcium phosphate/Al2O3 biocomposite coating on medical titanium using a hybrid technique of anodic oxidation and hydrothermal treatment. The pre- and post-anodized samples were investigated by scanning electron microscopy (SEM), energy dispersive analysis of X-ray (EDAX), transmission electron microscopy (TEM), and X-ray diffraction (XRD) techniques. The results indicated that porous anodic alumina film containing Ca and P was obtained on the as-prepared Al-Ti substrate through anodization, and the subsequent hydrothermal treatment led to the formation of calcium phosphate crystals. SEM and TEM results showed that calcium phosphate crystals were in nanometer, in-situ embedded in the walls of the cylindrical structure of anodic alumina, and finally formed a thin and porous top layer on the anodic alumina layer. The nanometer effect of calcium phosphate top layer, the porous and cylindrical microstructure of calcium phosphate/Al2O3-Ti, and the in-situ growth effect are expect to possess a very good combination of bioactivity and mechanical integrity.
