To assess the role of oxidative metabolism and nitric oxide synthesis for elucid a ting their pathophysiological mechanisms in a Tibetan patient with essential hyp ertension Methods The serum levels of total supero...To assess the role of oxidative metabolism and nitric oxide synthesis for elucid a ting their pathophysiological mechanisms in a Tibetan patient with essential hyp ertension Methods The serum levels of total superoxide dismutase (T SOD), malondialdehyde (MDA), total antioxidant capacity (T AOC), nitric oxide (NO) and nitric oxide synthase (NOS) were assayed in sixty native Tibetans (thirty hypertensive patients and t hirty healthy volunteers as control) Results The levels of T SOD, T AOC, NO and NOS were significantly lower in the patien t group than in the control group ( P <0 01); MDA was significantly higher in the patient group than in the control group ( P <0 01) The level of MDA ha d a strong negative correlation with T SOD, T AOC, NO and NOS ( r =-0 82, -0 76, -0 79, -0 73, respectively, P <0 001 for all) Conclusion Tibetan patients with essential hypertension (EH) may have underlying oxidative metabolism dysfunction and depressed NO synthesis, both responsible for the hype rtensive process展开更多
In Garze Tibetan autonomous prefecture inSichuan province, China, 41 echinococciasis patientswho had received surgical treatment were recruitedin the study, and 82 health persons who had livedin Garze for at least 10 ...In Garze Tibetan autonomous prefecture inSichuan province, China, 41 echinococciasis patientswho had received surgical treatment were recruitedin the study, and 82 health persons who had livedin Garze for at least 10 years were selected ascontrols. The serum levels of Zn, Se and Cu of thecases and controls were detected. The resultsshowed that most echinococciasis cases weredistributed in Shiqu county （17.1%, 7/41）, and only1 case was distributed in Yajiang county （2.4%）. Themale to female ratio of the cases was 1：1.56. Theechinococciasis patients were mainly aged 30-39years （36.59%, 15/41）. And, the cases aged 20-49years accounted for 68.29% （28/41）. Comparedwith health controls, the serum levels of Zn and Seof the cases significantly declined. However, theserum level of Cu of the cases had no significantlychange. It was confirmed that the serum levels ofZn and Se were interrelated with the prevalence ofechinococciasis.展开更多
目的探讨对接受经尿道前列腺电切除术（transurethral resection of prostate,TURP）的藏区老年患者实施心理干预的方法,以解除其因语言沟通困难等产生的心理障碍,从而提高就医依从性。方法选取我院2013年1-6月行TURP术的36名藏区老年...目的探讨对接受经尿道前列腺电切除术（transurethral resection of prostate,TURP）的藏区老年患者实施心理干预的方法,以解除其因语言沟通困难等产生的心理障碍,从而提高就医依从性。方法选取我院2013年1-6月行TURP术的36名藏区老年患者（对照组）,2013年7-12月行TURP术的43名藏区老年患者（实验组）,对照组实施常规护理服务模式,实验组实施心理干预服务模式,比较两组的相关指标。结果实施心理干预后,患者手术焦虑紧张程度明显减轻,疾病健康相关知识知晓程度和护理服务质量满意度大幅提高,与对照组比较差异有统计学意义（P〈0.05）。结论对藏区老年患者实施灵活的个性化心理干预,能减轻藏区患者对手术的恐惧感及手术所致的痛苦,增加信任感,提高其对治疗的依从性,从而促进患者疾病的好转和康复。展开更多
文摘To assess the role of oxidative metabolism and nitric oxide synthesis for elucid a ting their pathophysiological mechanisms in a Tibetan patient with essential hyp ertension Methods The serum levels of total superoxide dismutase (T SOD), malondialdehyde (MDA), total antioxidant capacity (T AOC), nitric oxide (NO) and nitric oxide synthase (NOS) were assayed in sixty native Tibetans (thirty hypertensive patients and t hirty healthy volunteers as control) Results The levels of T SOD, T AOC, NO and NOS were significantly lower in the patien t group than in the control group ( P <0 01); MDA was significantly higher in the patient group than in the control group ( P <0 01) The level of MDA ha d a strong negative correlation with T SOD, T AOC, NO and NOS ( r =-0 82, -0 76, -0 79, -0 73, respectively, P <0 001 for all) Conclusion Tibetan patients with essential hypertension (EH) may have underlying oxidative metabolism dysfunction and depressed NO synthesis, both responsible for the hype rtensive process
基金financially supported by the Grant for the National Major Science and Technology Project(grant No.2012ZX10004-220,No.2008ZX10004-011)
文摘In Garze Tibetan autonomous prefecture inSichuan province, China, 41 echinococciasis patientswho had received surgical treatment were recruitedin the study, and 82 health persons who had livedin Garze for at least 10 years were selected ascontrols. The serum levels of Zn, Se and Cu of thecases and controls were detected. The resultsshowed that most echinococciasis cases weredistributed in Shiqu county （17.1%, 7/41）, and only1 case was distributed in Yajiang county （2.4%）. Themale to female ratio of the cases was 1：1.56. Theechinococciasis patients were mainly aged 30-39years （36.59%, 15/41）. And, the cases aged 20-49years accounted for 68.29% （28/41）. Comparedwith health controls, the serum levels of Zn and Seof the cases significantly declined. However, theserum level of Cu of the cases had no significantlychange. It was confirmed that the serum levels ofZn and Se were interrelated with the prevalence ofechinococciasis.
文摘目的探讨对接受经尿道前列腺电切除术（transurethral resection of prostate,TURP）的藏区老年患者实施心理干预的方法,以解除其因语言沟通困难等产生的心理障碍,从而提高就医依从性。方法选取我院2013年1-6月行TURP术的36名藏区老年患者（对照组）,2013年7-12月行TURP术的43名藏区老年患者（实验组）,对照组实施常规护理服务模式,实验组实施心理干预服务模式,比较两组的相关指标。结果实施心理干预后,患者手术焦虑紧张程度明显减轻,疾病健康相关知识知晓程度和护理服务质量满意度大幅提高,与对照组比较差异有统计学意义（P〈0.05）。结论对藏区老年患者实施灵活的个性化心理干预,能减轻藏区患者对手术的恐惧感及手术所致的痛苦,增加信任感,提高其对治疗的依从性,从而促进患者疾病的好转和康复。
