Temple of the Three Sus,which was first established during the Yuan Dynasty,features a natural,unrestrained,and classically elegant garden architectural style.This paper discusses the multiple characteristics and mean...Temple of the Three Sus,which was first established during the Yuan Dynasty,features a natural,unrestrained,and classically elegant garden architectural style.This paper discusses the multiple characteristics and meanings of traditional architectural decorative patterns at Temple of the Three Sus from a semiotic perspective.First,it analyzes the denotative aspects of these patterns,including their stylistic forms,structural frameworks,and craftsmanship techniques.Second,the paper classifies the traditional architectural decorative patterns of the Temple of the Three Sus based on the types of sources of these patterns and interprets the implied meanings of each.Finally,the paper explores the application of these traditional decorative patterns in modern urban design,specifically in Meishan City,discussing the inheritance and innovation of these patterns in contemporary urban design and emphasizing the importance of integrating tradition with modernity.展开更多
At the beginning of the initial cholera outbreak in China,Wang Qingren(王清任),after years of clinical trials,became an early representative who discovered the infectious characteristics and observed the course of cho...At the beginning of the initial cholera outbreak in China,Wang Qingren(王清任),after years of clinical trials,became an early representative who discovered the infectious characteristics and observed the course of cholera in the field of traditional Chinesse medicine(TCM).Kou Langao(寇兰皋)and Xu Zimo(徐子默),both medical practitioners,constructed a diagnosis and treatment system for cholera with cold patterns under the theory of typhoid.They represented“School of Cholera with Cold Patterns”(SCCP).In the 1860s,with the influence of Wang Shixiong’s(王士雄)studies on the nature of cholera under the theory of epidemic febrile disease,the“School of Cholera with Heated Patterns”(SCHP)prevailed thereafter.The two schools complemented each other in theories and contributed to the integrity of TCM in cholera diagnosis and treatment.By reviewing previous literature,books,clinical cases,and historical materials in medical field,this article aims 1)to summarise the influence of TCM on the cognitive development towards cholera in the late Qing dynasty;2)to explore the origin of the controversy between SCCP and SCHP from historical evidence;3)to summarize the historical lessons from the debate over cholera in TCM based on the principle of treatment based on pattern identification,and offer suggestions for the current prevention and treatment of new diseases using TCM.展开更多
Medicinal plants are the primary material basis for disease prevention and treatment in traditional Chinese medicine(TCM).The conservation and sustainable utilization of these medicinal plants is critical for the deve...Medicinal plants are the primary material basis for disease prevention and treatment in traditional Chinese medicine(TCM).The conservation and sustainable utilization of these medicinal plants is critical for the development of the TCM industry.However,wild medicinal plant resources have sharply declined in recent decades.To ameliorate the shortage of medicinal plant resources,it is essential to explore the development potential of the TCM industry in different geographical regions.For this purpose,we examined the spatial distribution of commonly used medicinal plants in China,the number of Chinese medicinal material markets,and the number of TCM decoction piece enterprises.Specifically,multispecies superimposition analysis and Thiessen polygons were used to reveal the optimal range for planting bulk medicinal plants and the ideal regions for building Chinese medicinal material markets,respectively.Furthermore,we quantitatively analyzed mismatches between the spatial distribution of commonly used medicinal plant richness,Chinese medicinal material markets,and TCM decoction piece enterprises.We found that the areas suitable for growing commonly used medicinal plants in China were mainly distributed in Hengduan Mountain,Nanling Mountain,Wuling Mountain,and Daba Mountain areas.The Thiessen polygon network based on Chinese medicinal material market localities showed there are currently fewer markets in southwestern,northwestern,and northeastern China than in central and southern China.TCM decoction piece enterprises are concentrated in a few provinces,such as Hebei and Jiangxi.We found that the distribution of commonly used medicinal plants,Chinese medicinal material markets and TCM decoction piece enterprises are mismatched in Henan,Shaanxi,Hunan,Hubei,Zhejiang,Fujian,Chongqing,and Xizang.We recommend strengthening development of the TCM industry in Henan,Hunan,Zhejiang,Shaanxi,Hubei,Chongqing,Fujian,and Xizang;building more Chinese medicinal material markets in southwestern,northwestern,and northeastern China;and establishing medicinal plant nurseries in resource-rich provinces to better protect and domesticate local medicinal plants.展开更多
The traditional villages in the Tujia area of southwest Hubei are comprehensive carriers of historical culture,architectural skills and landscape patterns.The traditional villages have formed a unique village landscap...The traditional villages in the Tujia area of southwest Hubei are comprehensive carriers of historical culture,architectural skills and landscape patterns.The traditional villages have formed a unique village landscape,which is an important part of China's national culture and landscape resources.Based on the classification of landscape characteristics of 86 traditional Tujia villages in southwest Hubei,the study explored the landscape spatial pattern characteristics of traditional villages by GIS spatial analysis method.展开更多
China traditional patterns are of various kinds,and the performance of the content is also very rich.In the development of traditional pattern evolvement process,it experienced a plurality of historical period change,...China traditional patterns are of various kinds,and the performance of the content is also very rich.In the development of traditional pattern evolvement process,it experienced a plurality of historical period change,and it has a certain period of time the representative style, so the traditional patterns have more cultural meaning.We can say that development track Of traditional pattern have a close relationship with the Chinese history and culture ,which reflects the aesthetic characteristics of different cultural background of each period.In this paper, from the analysis of Chinese traditional patterns of aesthetic characteristics in different periods,it researches the cultural meaning of traditional patterns.展开更多
A total of 126 traditional villages in Guangdong were selected for research to analyze their spatial distribution pattern, spatial autocorrelation, and Han subgroup characteristics through the spatial analysis with GI...A total of 126 traditional villages in Guangdong were selected for research to analyze their spatial distribution pattern, spatial autocorrelation, and Han subgroup characteristics through the spatial analysis with GIS. The results showed that the traditional villages in Guangdong were distributed compactly, which was similar to that in other provinces; on the prefecture-level city scale, they were mainly distributed in Meizhou, Qingyuan, Zhanjiang, and Zhaoqing, showing a central distribution; on the regional scale, they were mainly distributed in northern Guangdong and the Pearl River Delta, indicating an unbalanced distribution; their density of spatial distribution showed a significant difference with a provincial distribution density of 0.59 per thousand km^2 and the highest distribution density of 2.14 per thousand km^2; there were four gathering areas accommodating many traditional villages, namely Meizhou-Chaoshan area, Guangfo-Dongguan area, Leizhou in Zhanjiang, and Lianzhou in Qingyuan; the spatial distribution of traditional villages, which presented a pattern of hot spot—sub-hot spot—sub-cold spot—cold spot, had a significant global spatial autocorrelation, and areas in similar sizes were tending towards gathering; traditional villages in Guangdong belonged to the Cantonese-speaking group and Hakka-speaking group with a density of 0.59 per thousand km^2 and 0.48 per thousand km^2 respectively, and Han subgroup with the highest distribution density was the minority areas of 1.31 per thousand km^2, followed by Shaozhou dialect area with a density of 1.00 per thousand km^2.展开更多
Artificial intelligence(AI) aims to mimic human cognitive functions and execute intellectual activities like that performed by humans dealing with an uncertain environment. The rapid development of AI technology provi...Artificial intelligence(AI) aims to mimic human cognitive functions and execute intellectual activities like that performed by humans dealing with an uncertain environment. The rapid development of AI technology provides powerful tools to analyze massive amounts of data, facilitating physicians to make better clinical decisions or even replace human judgment in healthcare.Advanced AI technology also creates novel opportunities for exploring the scientific basis of traditional Chinese medicine(TCM) and developing the standardization and digitization of TCM pulse diagnostic methodology. In the present study, we review and discuss the potential application of AI technology in TCM pulse diagnosis. The major contents include the following aspects:(1) a brief introduction of the general concepts and knowledge of TCM pulse diagnosis or palpation,(2) landmark developments in AI technology and the applications of common AI deep learning algorithms in medical practice,(3) the current progress of AI technology in TCM pulse diagnosis,(4) challenges and perspectives of AI technology in TCM pulse diagnosis. In conclusion, the pairing of TCM with modern AI technology will bring novel insights into understanding the scientific principles underlying TCM pulse diagnosis and creating opportunities for the development of AI deep learning technology for the standardization and digitalization of TCM pulse diagnosis.展开更多
Study on the relationship between landscape beauty and ecological beauty is an important scientifi c problem that refl ects the nature of man-land relation, and current academic researches on this topic are most based...Study on the relationship between landscape beauty and ecological beauty is an important scientifi c problem that refl ects the nature of man-land relation, and current academic researches on this topic are most based on a single perspective. Therefore, this paper took the Confucius Temple–Qinhuai River Scenic Area in Nanjing City as a typical case of urban traditional cultural tourism destination, adopted landscape pattern indexes and balanced incomplete block comparison and evaluation method as the evaluation standards of ecological beauty and landscape beauty, and analyzed the coupling characteristics and rules of landscape pattern and landscape aesthetics. The results showed that(a) The overall landscape of the study area had higher fragmentation degree, but different landscape groups were infl uenced by different human interventions, landscape patches showed moderate diversity and heterogeneity, patch area, spatial distribution and spatial aggregation degree showed structural differences.(b) The locals and visitors had aesthetic perception of the study area, but preferred the beautiful natural scenery of the Qinhuai River, as well as the historical buildings and cultural landscapes that contain rich memories of the city.(c) Landscape pattern and landscape aesthetics showed coupled complementation and harmonious coexistence. The Confucius Temple–Qinhuai River Scenic Area has profound historical and cultural background, but it has witnessed gradual loss of cultural characteristics and fast "delocalization" against the background of rapid urbanization. As an urban traditional cultural tourism destination, it carries the responsibility of protecting city memories and inheriting regional cultures.展开更多
With the rapid development of animation design and other computer science techniques, the application of computer based design pattern is urgently appreciated. In this paper, we conduct research on the similarities an...With the rapid development of animation design and other computer science techniques, the application of computer based design pattern is urgently appreciated. In this paper, we conduct research on the similarities and differences between Flash ActionScript based animation design technique and traditional design pattern. Current computer animation technology has developed rapidly at home and abroad, in the production of 2D and 3D animation, creating many new methods, new technology, using the computer aided animation in different degree to replace the manual animation technology, computerized gradually. We could significantly conclude from the user interface and the sample example of the pattern of computer based animation design. In the future, we plan to research more to touch the latest techniques related to flash technique.展开更多
Zhongjing Zhang’s Shang Han Lun(Treatise on Cold-induced Diseases,an ancient Chinese medical book written by Zhongjing Zhang in the Eastern Han Dynasty)was pioneering to conduct the Six-Meridian Pattern Identificatio...Zhongjing Zhang’s Shang Han Lun(Treatise on Cold-induced Diseases,an ancient Chinese medical book written by Zhongjing Zhang in the Eastern Han Dynasty)was pioneering to conduct the Six-Meridian Pattern Identification,which provided later generations with a theoretical basis for the treatment of Exogenous Febrile Diseases.The coronavirus disease 2019 belongs to the category of“Pestilence”(the general term for virulent infectious epidemic diseases)in“Febrile Diseases”(the general term for acute externally contracted diseases caused by Warm Pathogens,with fever as the chief manifestation,also known as Warm Diseases)and the treatment of coronavirus disease 2019 is mostly based on the Triple Energizer Pattern Identification(the a categorization of Pattern Identification according to the theory of the Triple Energizer)or Defense,Qi,Nutrient and Blood Pattern Identification(the categorization of Febrile Diseases Pattern Identification according to the theory of Defense,Qi,Nutrient and Blood which indicates the stages of the clinical course with corresponding pathological changes).Although the theory of Cold-induced Diseases(the condition caused by Cold,manifested as chills and fever,absence of sweating,headache and floating-tense pulse)and the theory of Febrile Disease seem to be entirely distinct with each other,Zhongjing Zhang’s theory contained Triple Energizer Pattern Identification or Defense,Qi,Nutrient and Blood Pattern Identification,and Triple Energizer Pattern Identification or Defense Qi,Nutrient and Blood Pattern Identification also contained Zhongjing Zhang’s Six-Meridian Pattern Identification(the categorization of Pattern Identification according to the theory of the Six Meridians,applied to the diagnosis of acute Febrile Diseases at different stages,and also useful for the Pattern Identification of other diseases).The basic principles and therapeutic methods of Cold-induced Diseases and Febrile Diseases are intertwined.Therefore,this paper will combine the two theories to analyze the traditional Chinese medicine syndromes of coronavirus disease 2019,and try to use Six-Meridian Pattern Identification to guide the treatment of this disease.展开更多
Background:Traditional Chinese medicine(TCM)syndrome,also named syndrome,are comprehensive and integral analyses of clinical information which helps to guide different individualized treatment prescriptions.Methods:Th...Background:Traditional Chinese medicine(TCM)syndrome,also named syndrome,are comprehensive and integral analyses of clinical information which helps to guide different individualized treatment prescriptions.Methods:Thirty healthy controls and 80 colorectal cancer(CRC)patients(including 33 Spleen Qi Deficiency syndrome,23 Dampness Heat syndrome,17 Blood Stasis syndrome and 7 other syndrome)were enrolled into this study.Human mRNAs were extracted from peripheral blood mononuclear cells.The gene expression for CRC patients with different TCM syndrome was determined by microarray and qRT-PCR.Results:Spleen Qi Deficiency,Dampness Heat and Blood Stasis were the most common syndromes in CRC patients.There is a significant difference was found in mRNA expression levels(especially for PIK3CA,STAT3,SOX9 and KDM5C)among Spleen Qi Deficiency,Dampness Heat and Blood Stasis syndrome groups.The higher mRNA levels of JNK1,TP53,MLH1,MSH6,PMS2,SOCS3,TCF7L2,FAM123B,PSAP,FBXW7,SALL4 and the lower expression of inflammatory cytokine IL-6 were found in Spleen Qi Deficiency group but not other syndrome types.The higher mRNA levels of KRAS,MUC16,EGFR,GRASP65,PIK3CA,MAPK7,CD24,STAT3,SLC11A1,Bcl-2,TXNDC17 and some inflammatory cytokines(IL-6,IL-23,TNF-a,CXCR4)were found in Dampness Heat group but not other syndrome types.Blood Stasis syndrome showed higher expression of SOX9,MLH1,MSH6,KDM5C,PCDH11X,PSAP and SALL4,and lower mRNA levels of PIK3CA,CD24,STAT3,CXCR4,TXNDC17 and TP53.The CRC patients with Dampness Heat syndrome might have a poor prognosis than other syndrome types.Conclusion:The identification of syndrome conditions had different impacts on CRC prognosis,and which might be related with different mRNA expression levels.Some oncogenes and pro-inflammatory cytokines were highly expressed in Dampness Heat group but not other syndrome types,suggesting that the CRC patients with Dampness Heat syndrome might have a poor prognosis.Our results prelimitarily uncovered the molecular basis of syndrome differences in CRC prognosis,a better understanding for TCM treatment of CRC.展开更多
In 2018,the 11^(th) Edition of the International Classification of Diseases(ICD-11)defined a diagnostic code list for standard traditional medicine(TM)conditions.The codes improve patient safety by providing more comp...In 2018,the 11^(th) Edition of the International Classification of Diseases(ICD-11)defined a diagnostic code list for standard traditional medicine(TM)conditions.The codes improve patient safety by providing more comprehensive and accurate medical records for hospitals in the Western Pacific Region.In these facilities,TM is often a standard of care for those populations.In several mainstream media sources,writers are circumventing evidence-based peer-reviewed medical literature by unduly influencing public opinion and,in this case,against the new ICD-11 codes.The dangers imposed by the transgression of popular writing onto the discipline of peer-reviewed works are present since best practices in medical record-keeping will fail without the inclusion of TM in the ICD-11 codes.Such failures directly affect the health of the patients and policymakers in regions where TM and conventional medicine are combined.This article investigates the boundaries between substantial evidence and popular opinion.In this era where media is used to manipulate evidence,the reader’s use of sound judgment and critical thought are thwarted.This article also challenges three controversial themes in pop literature,including the threat to endangered species,increased patient risk,and contaminants in the TM.These themes are made without evidence and are,in fact,of flawed logic.There is no reason to assume that improved medical record-keeping and knowledge of patient cases increase risks.展开更多
On the basis of analysis on both the typical characteristics of Chinese traditional clothing and trendy fashion on present market that is inspired from it,this paper illustrates several re-creation methods of Chinese ...On the basis of analysis on both the typical characteristics of Chinese traditional clothing and trendy fashion on present market that is inspired from it,this paper illustrates several re-creation methods of Chinese traditional clothing.These suggestions would push this oriental traditional clothing to a new high in world fashion field and adopted by more and more common people.展开更多
Objective: To describe patterns of utilization of traditional Chinese medicine(TCM) in the treatment of patients with coronavirus disease 2019(COVID-19).Methods: Adult patients with COVID-19 who received TCM treatment...Objective: To describe patterns of utilization of traditional Chinese medicine(TCM) in the treatment of patients with coronavirus disease 2019(COVID-19).Methods: Adult patients with COVID-19 who received TCM treatment were divided into a non-serious group(mild and moderate types) and a serious group(severe and critical types) according to their admission conditions. The medical records and prescriptions of these patients were investigated to determine their TCM utilization patterns.Results: In all, 3,872 COVID-19 patients were included. Oral Chinese traditional patent medicine(CPM) was the most commonly used type of TCM(83.2%), fol owed by decoction(64.4%). As for medication pattern, the proportion of multi-drug combinations was higher than single drug use(55.0% vs. 45.0%). Decoction combined with oral CPM was the most common combination(39.1%,1,514/3,872). Oral y administered, injected, and external y applied CPM were significantly more common in the serious group than in the non-serious, while decoction and non-drug TCM treatments were more common in the non-serious than in the serious group.Multi-drug combinations were used for the majority of patients in both groups, mainly in the form of decoction combined with oral CPM.Serious patients were analysed by three groups of different prognoses and outcomes, including discharged after improvement,discharged after relapse and improvement, died final y. The two most common medication patterns were decoction combined with oral CPM and oral CPM alone in the two final y discharged groups. Oral CPM alone or used in combination with injected CPM were seen most commonly in the death group. Significant differences were established in medication patterns among patients in these three groups.Conclusions: Oral CPM was the mainly used TCM for COVID-19 patients, followed by decoction. More common medication pattern was multi-drug combination, especially decoction combined with oral CPM. The treatment measures and medication patterns of TCM commonly used in COVID-19 patients with the range of conditions found in this study should be further explored in the future to provide a more complete reference for COVID-19 treatment.展开更多
To analyze the herbal medicine prescribing patterns of contemporary famous old traditional Chinese medicine doctors in treating coronary heart disease,based on data mining technology,so as to provide useful insights i...To analyze the herbal medicine prescribing patterns of contemporary famous old traditional Chinese medicine doctors in treating coronary heart disease,based on data mining technology,so as to provide useful insights into the clinical practice.Methods:Databases,including Medline(January 1966 to December 2019),Wanfang(January 1982 to December 2019),VIP Database(January 1989 to December 2019),CNKI(January 1979 to December 2019),CBMdisc(January 1978 to December 2019),and Classic Case Collection from Contemporary Famous Old Traditional Chinese Medicine Doctors were searched,and 224 eligible studies involving 416 patients were entered into the case study database after data processing.Frequency analysis and association rule analysis were used to investigate the prescribing patterns of contemporary famous old traditional Chinese medicine doctors in treating coronary heart disease.Results:In total 290 kinds of Chinese herbal drugs and 19 core drugs were used in the cases studied.The most commonly used categories were“Qi-Tonifying Drugs”,“Blood-Activating Drugs”,and“Phlegm-Eliminating Drugs”.The association rule analysis identified 14 commonly used herbal pairs,19 three-drug combinations,and 1 four-drug combination.Conclusion:Contemporary famous old traditional Chinese medicine doctors considered warming heart yang as an extremely important approach to treat coronary heart disease based on Zhang Zhongjing’s treatment for chest painful obstruction caused by“Inactivity of Chest Yang”(blockade of phlegm turbidity).Both symptoms and root causes were addressed in the formulas prescribed by these doctors.“Tonifying Qi,Nourishing Yin,Activating Blood,and Eliminating Phlegm”were the most commonly used therapeutic methods for patients with coronary heart disease.展开更多
文摘Temple of the Three Sus,which was first established during the Yuan Dynasty,features a natural,unrestrained,and classically elegant garden architectural style.This paper discusses the multiple characteristics and meanings of traditional architectural decorative patterns at Temple of the Three Sus from a semiotic perspective.First,it analyzes the denotative aspects of these patterns,including their stylistic forms,structural frameworks,and craftsmanship techniques.Second,the paper classifies the traditional architectural decorative patterns of the Temple of the Three Sus based on the types of sources of these patterns and interprets the implied meanings of each.Finally,the paper explores the application of these traditional decorative patterns in modern urban design,specifically in Meishan City,discussing the inheritance and innovation of these patterns in contemporary urban design and emphasizing the importance of integrating tradition with modernity.
基金This study is financed by the grants from the Fundamental Research Funds for the Central Universities(No.23JNQMX48 and No.23JNSYS04)Major Project of the Key Research Bases of Humanities and Social Sciences of Ministry of Education(No.22JJD770054).
文摘At the beginning of the initial cholera outbreak in China,Wang Qingren(王清任),after years of clinical trials,became an early representative who discovered the infectious characteristics and observed the course of cholera in the field of traditional Chinesse medicine(TCM).Kou Langao(寇兰皋)and Xu Zimo(徐子默),both medical practitioners,constructed a diagnosis and treatment system for cholera with cold patterns under the theory of typhoid.They represented“School of Cholera with Cold Patterns”(SCCP).In the 1860s,with the influence of Wang Shixiong’s(王士雄)studies on the nature of cholera under the theory of epidemic febrile disease,the“School of Cholera with Heated Patterns”(SCHP)prevailed thereafter.The two schools complemented each other in theories and contributed to the integrity of TCM in cholera diagnosis and treatment.By reviewing previous literature,books,clinical cases,and historical materials in medical field,this article aims 1)to summarise the influence of TCM on the cognitive development towards cholera in the late Qing dynasty;2)to explore the origin of the controversy between SCCP and SCHP from historical evidence;3)to summarize the historical lessons from the debate over cholera in TCM based on the principle of treatment based on pattern identification,and offer suggestions for the current prevention and treatment of new diseases using TCM.
基金funded by the National Natural Science Foundation of China(31800178)the Strategic Priority Research Programme of the Chinese Academy of Sciences(XDB31000000)the Youth Innovation Promotion Association of the Chinese Academy of Sciences(2021077).
文摘Medicinal plants are the primary material basis for disease prevention and treatment in traditional Chinese medicine(TCM).The conservation and sustainable utilization of these medicinal plants is critical for the development of the TCM industry.However,wild medicinal plant resources have sharply declined in recent decades.To ameliorate the shortage of medicinal plant resources,it is essential to explore the development potential of the TCM industry in different geographical regions.For this purpose,we examined the spatial distribution of commonly used medicinal plants in China,the number of Chinese medicinal material markets,and the number of TCM decoction piece enterprises.Specifically,multispecies superimposition analysis and Thiessen polygons were used to reveal the optimal range for planting bulk medicinal plants and the ideal regions for building Chinese medicinal material markets,respectively.Furthermore,we quantitatively analyzed mismatches between the spatial distribution of commonly used medicinal plant richness,Chinese medicinal material markets,and TCM decoction piece enterprises.We found that the areas suitable for growing commonly used medicinal plants in China were mainly distributed in Hengduan Mountain,Nanling Mountain,Wuling Mountain,and Daba Mountain areas.The Thiessen polygon network based on Chinese medicinal material market localities showed there are currently fewer markets in southwestern,northwestern,and northeastern China than in central and southern China.TCM decoction piece enterprises are concentrated in a few provinces,such as Hebei and Jiangxi.We found that the distribution of commonly used medicinal plants,Chinese medicinal material markets and TCM decoction piece enterprises are mismatched in Henan,Shaanxi,Hunan,Hubei,Zhejiang,Fujian,Chongqing,and Xizang.We recommend strengthening development of the TCM industry in Henan,Hunan,Zhejiang,Shaanxi,Hubei,Chongqing,Fujian,and Xizang;building more Chinese medicinal material markets in southwestern,northwestern,and northeastern China;and establishing medicinal plant nurseries in resource-rich provinces to better protect and domesticate local medicinal plants.
文摘The traditional villages in the Tujia area of southwest Hubei are comprehensive carriers of historical culture,architectural skills and landscape patterns.The traditional villages have formed a unique village landscape,which is an important part of China's national culture and landscape resources.Based on the classification of landscape characteristics of 86 traditional Tujia villages in southwest Hubei,the study explored the landscape spatial pattern characteristics of traditional villages by GIS spatial analysis method.
文摘China traditional patterns are of various kinds,and the performance of the content is also very rich.In the development of traditional pattern evolvement process,it experienced a plurality of historical period change,and it has a certain period of time the representative style, so the traditional patterns have more cultural meaning.We can say that development track Of traditional pattern have a close relationship with the Chinese history and culture ,which reflects the aesthetic characteristics of different cultural background of each period.In this paper, from the analysis of Chinese traditional patterns of aesthetic characteristics in different periods,it researches the cultural meaning of traditional patterns.
基金Sponsored by Guangdong Provincial Natural Science Foundation(2015A030313852)Guangdong Provincial Scientific and Technological Programs(2014A020219006,2015B070701020)
文摘A total of 126 traditional villages in Guangdong were selected for research to analyze their spatial distribution pattern, spatial autocorrelation, and Han subgroup characteristics through the spatial analysis with GIS. The results showed that the traditional villages in Guangdong were distributed compactly, which was similar to that in other provinces; on the prefecture-level city scale, they were mainly distributed in Meizhou, Qingyuan, Zhanjiang, and Zhaoqing, showing a central distribution; on the regional scale, they were mainly distributed in northern Guangdong and the Pearl River Delta, indicating an unbalanced distribution; their density of spatial distribution showed a significant difference with a provincial distribution density of 0.59 per thousand km^2 and the highest distribution density of 2.14 per thousand km^2; there were four gathering areas accommodating many traditional villages, namely Meizhou-Chaoshan area, Guangfo-Dongguan area, Leizhou in Zhanjiang, and Lianzhou in Qingyuan; the spatial distribution of traditional villages, which presented a pattern of hot spot—sub-hot spot—sub-cold spot—cold spot, had a significant global spatial autocorrelation, and areas in similar sizes were tending towards gathering; traditional villages in Guangdong belonged to the Cantonese-speaking group and Hakka-speaking group with a density of 0.59 per thousand km^2 and 0.48 per thousand km^2 respectively, and Han subgroup with the highest distribution density was the minority areas of 1.31 per thousand km^2, followed by Shaozhou dialect area with a density of 1.00 per thousand km^2.
基金We thank for the funding support form the Health and Medical Research Fund,Hong Kong SAR(No.17181811).
文摘Artificial intelligence(AI) aims to mimic human cognitive functions and execute intellectual activities like that performed by humans dealing with an uncertain environment. The rapid development of AI technology provides powerful tools to analyze massive amounts of data, facilitating physicians to make better clinical decisions or even replace human judgment in healthcare.Advanced AI technology also creates novel opportunities for exploring the scientific basis of traditional Chinese medicine(TCM) and developing the standardization and digitization of TCM pulse diagnostic methodology. In the present study, we review and discuss the potential application of AI technology in TCM pulse diagnosis. The major contents include the following aspects:(1) a brief introduction of the general concepts and knowledge of TCM pulse diagnosis or palpation,(2) landmark developments in AI technology and the applications of common AI deep learning algorithms in medical practice,(3) the current progress of AI technology in TCM pulse diagnosis,(4) challenges and perspectives of AI technology in TCM pulse diagnosis. In conclusion, the pairing of TCM with modern AI technology will bring novel insights into understanding the scientific principles underlying TCM pulse diagnosis and creating opportunities for the development of AI deep learning technology for the standardization and digitalization of TCM pulse diagnosis.
基金Sponsored by Youth Program of National Natural Science Foundation of China(41401152)Youth Program of Humanities and Social Sciences Foundation of the Ministry of Education(14YJCZH228)+1 种基金Domestic Senior Visiting Scholar Plan of Jiangsu Provincial Higher Vocational Colleges(2015FX036)Outstanding Young Teacher Cultivation Program of Jiangsu Universities and Colleges"Blue Project"
文摘Study on the relationship between landscape beauty and ecological beauty is an important scientifi c problem that refl ects the nature of man-land relation, and current academic researches on this topic are most based on a single perspective. Therefore, this paper took the Confucius Temple–Qinhuai River Scenic Area in Nanjing City as a typical case of urban traditional cultural tourism destination, adopted landscape pattern indexes and balanced incomplete block comparison and evaluation method as the evaluation standards of ecological beauty and landscape beauty, and analyzed the coupling characteristics and rules of landscape pattern and landscape aesthetics. The results showed that(a) The overall landscape of the study area had higher fragmentation degree, but different landscape groups were infl uenced by different human interventions, landscape patches showed moderate diversity and heterogeneity, patch area, spatial distribution and spatial aggregation degree showed structural differences.(b) The locals and visitors had aesthetic perception of the study area, but preferred the beautiful natural scenery of the Qinhuai River, as well as the historical buildings and cultural landscapes that contain rich memories of the city.(c) Landscape pattern and landscape aesthetics showed coupled complementation and harmonious coexistence. The Confucius Temple–Qinhuai River Scenic Area has profound historical and cultural background, but it has witnessed gradual loss of cultural characteristics and fast "delocalization" against the background of rapid urbanization. As an urban traditional cultural tourism destination, it carries the responsibility of protecting city memories and inheriting regional cultures.
文摘With the rapid development of animation design and other computer science techniques, the application of computer based design pattern is urgently appreciated. In this paper, we conduct research on the similarities and differences between Flash ActionScript based animation design technique and traditional design pattern. Current computer animation technology has developed rapidly at home and abroad, in the production of 2D and 3D animation, creating many new methods, new technology, using the computer aided animation in different degree to replace the manual animation technology, computerized gradually. We could significantly conclude from the user interface and the sample example of the pattern of computer based animation design. In the future, we plan to research more to touch the latest techniques related to flash technique.
文摘Zhongjing Zhang’s Shang Han Lun(Treatise on Cold-induced Diseases,an ancient Chinese medical book written by Zhongjing Zhang in the Eastern Han Dynasty)was pioneering to conduct the Six-Meridian Pattern Identification,which provided later generations with a theoretical basis for the treatment of Exogenous Febrile Diseases.The coronavirus disease 2019 belongs to the category of“Pestilence”(the general term for virulent infectious epidemic diseases)in“Febrile Diseases”(the general term for acute externally contracted diseases caused by Warm Pathogens,with fever as the chief manifestation,also known as Warm Diseases)and the treatment of coronavirus disease 2019 is mostly based on the Triple Energizer Pattern Identification(the a categorization of Pattern Identification according to the theory of the Triple Energizer)or Defense,Qi,Nutrient and Blood Pattern Identification(the categorization of Febrile Diseases Pattern Identification according to the theory of Defense,Qi,Nutrient and Blood which indicates the stages of the clinical course with corresponding pathological changes).Although the theory of Cold-induced Diseases(the condition caused by Cold,manifested as chills and fever,absence of sweating,headache and floating-tense pulse)and the theory of Febrile Disease seem to be entirely distinct with each other,Zhongjing Zhang’s theory contained Triple Energizer Pattern Identification or Defense,Qi,Nutrient and Blood Pattern Identification,and Triple Energizer Pattern Identification or Defense Qi,Nutrient and Blood Pattern Identification also contained Zhongjing Zhang’s Six-Meridian Pattern Identification(the categorization of Pattern Identification according to the theory of the Six Meridians,applied to the diagnosis of acute Febrile Diseases at different stages,and also useful for the Pattern Identification of other diseases).The basic principles and therapeutic methods of Cold-induced Diseases and Febrile Diseases are intertwined.Therefore,this paper will combine the two theories to analyze the traditional Chinese medicine syndromes of coronavirus disease 2019,and try to use Six-Meridian Pattern Identification to guide the treatment of this disease.
基金This research was supported by grants from National Natural Science Foundation of China(grant No.81874380,81672932,81730108 and 81973635)Zhejiang Provincial Natural Science Foundation of China for Distinguished Young Scholars(grant No.LR18H160001)+6 种基金Zhejiang Province Science and Technology Project of TCM(grant No.2019ZZ016)Zhejiang Province Medical Science and Technology Project(grant No.2017RC007)Talent Project of Zhejiang Association for Science and Technology(grant No.2017YCGC002)Key Project of Hangzhou Ministry of Science and Technology(grant No.20162013A07)Zhejiang Provincial Project for the Key Discipline of Traditional Chinese Medicine(grant No.2017-XK-A09)the Open Project Program of Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica(No.JKLPSE201807)the Project of the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
文摘Background:Traditional Chinese medicine(TCM)syndrome,also named syndrome,are comprehensive and integral analyses of clinical information which helps to guide different individualized treatment prescriptions.Methods:Thirty healthy controls and 80 colorectal cancer(CRC)patients(including 33 Spleen Qi Deficiency syndrome,23 Dampness Heat syndrome,17 Blood Stasis syndrome and 7 other syndrome)were enrolled into this study.Human mRNAs were extracted from peripheral blood mononuclear cells.The gene expression for CRC patients with different TCM syndrome was determined by microarray and qRT-PCR.Results:Spleen Qi Deficiency,Dampness Heat and Blood Stasis were the most common syndromes in CRC patients.There is a significant difference was found in mRNA expression levels(especially for PIK3CA,STAT3,SOX9 and KDM5C)among Spleen Qi Deficiency,Dampness Heat and Blood Stasis syndrome groups.The higher mRNA levels of JNK1,TP53,MLH1,MSH6,PMS2,SOCS3,TCF7L2,FAM123B,PSAP,FBXW7,SALL4 and the lower expression of inflammatory cytokine IL-6 were found in Spleen Qi Deficiency group but not other syndrome types.The higher mRNA levels of KRAS,MUC16,EGFR,GRASP65,PIK3CA,MAPK7,CD24,STAT3,SLC11A1,Bcl-2,TXNDC17 and some inflammatory cytokines(IL-6,IL-23,TNF-a,CXCR4)were found in Dampness Heat group but not other syndrome types.Blood Stasis syndrome showed higher expression of SOX9,MLH1,MSH6,KDM5C,PCDH11X,PSAP and SALL4,and lower mRNA levels of PIK3CA,CD24,STAT3,CXCR4,TXNDC17 and TP53.The CRC patients with Dampness Heat syndrome might have a poor prognosis than other syndrome types.Conclusion:The identification of syndrome conditions had different impacts on CRC prognosis,and which might be related with different mRNA expression levels.Some oncogenes and pro-inflammatory cytokines were highly expressed in Dampness Heat group but not other syndrome types,suggesting that the CRC patients with Dampness Heat syndrome might have a poor prognosis.Our results prelimitarily uncovered the molecular basis of syndrome differences in CRC prognosis,a better understanding for TCM treatment of CRC.
基金financed by grants from the National Major Science and Technology Projects of China (No. YB2019023)Independent Project of China Academy of Chinese Medical Sciences (No. ZZ12-002)
文摘In 2018,the 11^(th) Edition of the International Classification of Diseases(ICD-11)defined a diagnostic code list for standard traditional medicine(TM)conditions.The codes improve patient safety by providing more comprehensive and accurate medical records for hospitals in the Western Pacific Region.In these facilities,TM is often a standard of care for those populations.In several mainstream media sources,writers are circumventing evidence-based peer-reviewed medical literature by unduly influencing public opinion and,in this case,against the new ICD-11 codes.The dangers imposed by the transgression of popular writing onto the discipline of peer-reviewed works are present since best practices in medical record-keeping will fail without the inclusion of TM in the ICD-11 codes.Such failures directly affect the health of the patients and policymakers in regions where TM and conventional medicine are combined.This article investigates the boundaries between substantial evidence and popular opinion.In this era where media is used to manipulate evidence,the reader’s use of sound judgment and critical thought are thwarted.This article also challenges three controversial themes in pop literature,including the threat to endangered species,increased patient risk,and contaminants in the TM.These themes are made without evidence and are,in fact,of flawed logic.There is no reason to assume that improved medical record-keeping and knowledge of patient cases increase risks.
文摘On the basis of analysis on both the typical characteristics of Chinese traditional clothing and trendy fashion on present market that is inspired from it,this paper illustrates several re-creation methods of Chinese traditional clothing.These suggestions would push this oriental traditional clothing to a new high in world fashion field and adopted by more and more common people.
基金Special Project of Clinical Toxicology,Chinese Society of Toxicology(CST2020CT605,CST2021CT102)The second batch of Key Projects of Scientific Act for Drug Regulation of China,Grant/Award Number:[2021]3710+2 种基金Traditional Chinese Medicine Research Project,Health Commission of Hubei Province(ZY2021Z021)Special Project for Director,China Center for Evidence Based Traditional Chinese Medicine(2020YJSZX-2)National Science and Technology Major Project(2021YFC0863200)。
文摘Objective: To describe patterns of utilization of traditional Chinese medicine(TCM) in the treatment of patients with coronavirus disease 2019(COVID-19).Methods: Adult patients with COVID-19 who received TCM treatment were divided into a non-serious group(mild and moderate types) and a serious group(severe and critical types) according to their admission conditions. The medical records and prescriptions of these patients were investigated to determine their TCM utilization patterns.Results: In all, 3,872 COVID-19 patients were included. Oral Chinese traditional patent medicine(CPM) was the most commonly used type of TCM(83.2%), fol owed by decoction(64.4%). As for medication pattern, the proportion of multi-drug combinations was higher than single drug use(55.0% vs. 45.0%). Decoction combined with oral CPM was the most common combination(39.1%,1,514/3,872). Oral y administered, injected, and external y applied CPM were significantly more common in the serious group than in the non-serious, while decoction and non-drug TCM treatments were more common in the non-serious than in the serious group.Multi-drug combinations were used for the majority of patients in both groups, mainly in the form of decoction combined with oral CPM.Serious patients were analysed by three groups of different prognoses and outcomes, including discharged after improvement,discharged after relapse and improvement, died final y. The two most common medication patterns were decoction combined with oral CPM and oral CPM alone in the two final y discharged groups. Oral CPM alone or used in combination with injected CPM were seen most commonly in the death group. Significant differences were established in medication patterns among patients in these three groups.Conclusions: Oral CPM was the mainly used TCM for COVID-19 patients, followed by decoction. More common medication pattern was multi-drug combination, especially decoction combined with oral CPM. The treatment measures and medication patterns of TCM commonly used in COVID-19 patients with the range of conditions found in this study should be further explored in the future to provide a more complete reference for COVID-19 treatment.
基金This study was supported by Chongqing Young and Middle-aged Medical Senior Personnel Training Program[Grant no.1055]Inheritance Studio Construction Project of Famous Old Traditional Chinese Medicine Expert He Deying in Chongqing(YAY2020-20)+1 种基金Technology Innovation and Application Development Project of Chongqing Kewei Joint Traditional Chinese Medicine(No.:2020ZY023938)Special Project CSTC2020JXJL0052 of Chongqing Science and Technology Bureau for Performance Incentive and Guidance of Research Institutions.
文摘To analyze the herbal medicine prescribing patterns of contemporary famous old traditional Chinese medicine doctors in treating coronary heart disease,based on data mining technology,so as to provide useful insights into the clinical practice.Methods:Databases,including Medline(January 1966 to December 2019),Wanfang(January 1982 to December 2019),VIP Database(January 1989 to December 2019),CNKI(January 1979 to December 2019),CBMdisc(January 1978 to December 2019),and Classic Case Collection from Contemporary Famous Old Traditional Chinese Medicine Doctors were searched,and 224 eligible studies involving 416 patients were entered into the case study database after data processing.Frequency analysis and association rule analysis were used to investigate the prescribing patterns of contemporary famous old traditional Chinese medicine doctors in treating coronary heart disease.Results:In total 290 kinds of Chinese herbal drugs and 19 core drugs were used in the cases studied.The most commonly used categories were“Qi-Tonifying Drugs”,“Blood-Activating Drugs”,and“Phlegm-Eliminating Drugs”.The association rule analysis identified 14 commonly used herbal pairs,19 three-drug combinations,and 1 four-drug combination.Conclusion:Contemporary famous old traditional Chinese medicine doctors considered warming heart yang as an extremely important approach to treat coronary heart disease based on Zhang Zhongjing’s treatment for chest painful obstruction caused by“Inactivity of Chest Yang”(blockade of phlegm turbidity).Both symptoms and root causes were addressed in the formulas prescribed by these doctors.“Tonifying Qi,Nourishing Yin,Activating Blood,and Eliminating Phlegm”were the most commonly used therapeutic methods for patients with coronary heart disease.