The stability and reliability of a tilting index table should be considered at the design stage. A design method for the lightweight and improvement of the stability of the structure in a tilting index table was propo...The stability and reliability of a tilting index table should be considered at the design stage. A design method for the lightweight and improvement of the stability of the structure in a tilting index table was proposed using a commercial analysis program, ANSYS Workbench 12, by analyzing the static-thermal characteristics of the developed high-accuracy tilting index table at its design stage. The results of the performed structural analysis show that the maximum stress is generated at the stock tail part. An optimum design for the stock tail part was carried out to reduce the maximum stress and deformation. Also, the design variables were determined by considering the support of the stock tail part for the C-axis body. In the comparison of the results before and after the optimization, the maximum deformation and stress are improved by 2.8% and 8%, respectively.展开更多
Objective: to evaluate cilazapril in vasovagal syncope treatment. Method: eighty\|six cases of VVS patients found positive in TTT tilt were medicated with 2.5 mg cilazapril daily for three months and followed up by TT...Objective: to evaluate cilazapril in vasovagal syncope treatment. Method: eighty\|six cases of VVS patients found positive in TTT tilt were medicated with 2.5 mg cilazapril daily for three months and followed up by TTT. Results: seven cases quit due to cough or unexplained reason; 79 VVS patients had no more fainting spells; 75.95% of TTT results of patients changed to negative after 3 months therapy. The before and after cilazapril treatment average blood pressures (taken in lying position) were 121/73 mm Hg (1 mm Hg= 0.133kPa) and 120/76 mm Hg respectively ( P > 0.05); and mean heart rates were 68.63±12.37/min and 70.13±13.15/min respectively with no significant changes ( P > 0.05). Conclusion: Cilazapril was effective in treatment of VVS; did not affect normal blood pressure and heart rate; was safe; and had little side effect.展开更多
<strong>Aim</strong><span><span><span style="font-family:;" "=""><strong>:</strong> To describe post-infectious neurological aspects of COVID-19 in a ...<strong>Aim</strong><span><span><span style="font-family:;" "=""><strong>:</strong> To describe post-infectious neurological aspects of COVID-19 in a patient with progressive post-infectious peripheral (PNS), autonomic (ANS) and central nervous system (CNS) involvement due to SARS-CoV-2 infection. <b>Background</b> <b>and</b> <b><strong>Purpose</strong></b><strong>:</strong> A variety of neurological manifestations have been described in association with Covid-19, however</span></span></span><span><span><span style="font-family:;" "="">,</span></span></span><span><span><span style="font-family:;" "=""> progressive multisystem neurological aspects have not been described. <b><strong>Methods</strong></b><strong>:</strong> A case report detailing the history, examination, and infectious serology associated with SARS-CoV-2, and subsequent neurodiagnostic laboratory testing and treatment. <b><strong>Results</strong></b><strong>:</strong> Neurodiagnostic laboratory studies showed large-fiber demyelinating sensorimotor and painful small fiber sensory polyneuropathy, orthostatic hypotension, and hypometabolism of bilateral anterior and mesial temporal lobes with a possible frontal seizure focus. Treatment was initiated with high-dose immune globulin therapy. <b><strong>Conclusions</strong></b><strong>:</strong> The combination of PNS, ANS <span>and</span> CNS involvement in this patient was associated with post-infectious acquired immunity to SARS-CoV-2.</span></span></span>展开更多
Postural orthostatic tachycardia syndrome(POTS)is a disabling condition characterized by orthostatic intolerance with tachycardia in the absence of drop-in blood pressure.A custom-built near-infrared spectroscopy devi...Postural orthostatic tachycardia syndrome(POTS)is a disabling condition characterized by orthostatic intolerance with tachycardia in the absence of drop-in blood pressure.A custom-built near-infrared spectroscopy device(NIRS)is applied to monitor the muscle oxygenation,noninvasively in patients undergoing incremental head-up tilt table(HUT).Subjects(6 POTS patients and 6 healthy controls)underwent 30 mins of 70on a HUT.The results showed a signicant difference in deoxyhemoglobin(Hb),change-in-oxygenation(△Oxy)and blood volume(△BV)between patients and healthy controls.However,oxyhemoglobin(HbO_(2))showed a significantly faster rate of change in the healthy controls during the first 10 mins of the tilt and during the recovery.This NIRS muscle oximetry tool provides quantitative measurements of blood oxygenation monitoring in diseases such as POTS.展开更多
To investigate age and sex distribution of vasovagal syncope (VVS) patients undergoing head-up tilt table test (HUTT) at a tertiary hospital. The details of syncope patients who underwent HUTT at our department of...To investigate age and sex distribution of vasovagal syncope (VVS) patients undergoing head-up tilt table test (HUTT) at a tertiary hospital. The details of syncope patients who underwent HUTT at our department of cardiac function from January 2004 to December 2010 were reviewed. Of the 1 799 patients who underwent the HUTT, 854 tested positive, of which 558 (65.3%) were women, which were more than the women in the negative group (450, 47.6%) (p〈0.05). VVS patients showed a bimodal age distribution between 11 and 20 years of age and in the fourth decade. In almost all age groups, mixed response was the highest compared with vasodepressor and cardioinhibitory. VVS patients who underwent HUTT indicate bimodal distribution peaking before the second decade and the fourth decade. The incidence of females was twice that of males before the sixth decade, and old age occupies a small percentage of VVS with no other comorbidities.展开更多
基金Project(70004782) supported by the Regional Strategic Technology Development Program of the Ministry of Knowledge Economy(MKE) of KoreaProject(2011-0017407) supported by the National Research Foundation of Korea (NRF) Funded by the Korea Government (MEST)
文摘The stability and reliability of a tilting index table should be considered at the design stage. A design method for the lightweight and improvement of the stability of the structure in a tilting index table was proposed using a commercial analysis program, ANSYS Workbench 12, by analyzing the static-thermal characteristics of the developed high-accuracy tilting index table at its design stage. The results of the performed structural analysis show that the maximum stress is generated at the stock tail part. An optimum design for the stock tail part was carried out to reduce the maximum stress and deformation. Also, the design variables were determined by considering the support of the stock tail part for the C-axis body. In the comparison of the results before and after the optimization, the maximum deformation and stress are improved by 2.8% and 8%, respectively.
文摘Objective: to evaluate cilazapril in vasovagal syncope treatment. Method: eighty\|six cases of VVS patients found positive in TTT tilt were medicated with 2.5 mg cilazapril daily for three months and followed up by TTT. Results: seven cases quit due to cough or unexplained reason; 79 VVS patients had no more fainting spells; 75.95% of TTT results of patients changed to negative after 3 months therapy. The before and after cilazapril treatment average blood pressures (taken in lying position) were 121/73 mm Hg (1 mm Hg= 0.133kPa) and 120/76 mm Hg respectively ( P > 0.05); and mean heart rates were 68.63±12.37/min and 70.13±13.15/min respectively with no significant changes ( P > 0.05). Conclusion: Cilazapril was effective in treatment of VVS; did not affect normal blood pressure and heart rate; was safe; and had little side effect.
文摘<strong>Aim</strong><span><span><span style="font-family:;" "=""><strong>:</strong> To describe post-infectious neurological aspects of COVID-19 in a patient with progressive post-infectious peripheral (PNS), autonomic (ANS) and central nervous system (CNS) involvement due to SARS-CoV-2 infection. <b>Background</b> <b>and</b> <b><strong>Purpose</strong></b><strong>:</strong> A variety of neurological manifestations have been described in association with Covid-19, however</span></span></span><span><span><span style="font-family:;" "="">,</span></span></span><span><span><span style="font-family:;" "=""> progressive multisystem neurological aspects have not been described. <b><strong>Methods</strong></b><strong>:</strong> A case report detailing the history, examination, and infectious serology associated with SARS-CoV-2, and subsequent neurodiagnostic laboratory testing and treatment. <b><strong>Results</strong></b><strong>:</strong> Neurodiagnostic laboratory studies showed large-fiber demyelinating sensorimotor and painful small fiber sensory polyneuropathy, orthostatic hypotension, and hypometabolism of bilateral anterior and mesial temporal lobes with a possible frontal seizure focus. Treatment was initiated with high-dose immune globulin therapy. <b><strong>Conclusions</strong></b><strong>:</strong> The combination of PNS, ANS <span>and</span> CNS involvement in this patient was associated with post-infectious acquired immunity to SARS-CoV-2.</span></span></span>
基金UWM RGI 101×290(M.Ranji)the Bleser Endowed Chair in Neurology(H.Whelan)+1 种基金the Baumann Research Endowment(H.Whelan)Advancing Healthier Wisconsin grant #5520298(T.Chelimsky–PI)。
文摘Postural orthostatic tachycardia syndrome(POTS)is a disabling condition characterized by orthostatic intolerance with tachycardia in the absence of drop-in blood pressure.A custom-built near-infrared spectroscopy device(NIRS)is applied to monitor the muscle oxygenation,noninvasively in patients undergoing incremental head-up tilt table(HUT).Subjects(6 POTS patients and 6 healthy controls)underwent 30 mins of 70on a HUT.The results showed a signicant difference in deoxyhemoglobin(Hb),change-in-oxygenation(△Oxy)and blood volume(△BV)between patients and healthy controls.However,oxyhemoglobin(HbO_(2))showed a significantly faster rate of change in the healthy controls during the first 10 mins of the tilt and during the recovery.This NIRS muscle oximetry tool provides quantitative measurements of blood oxygenation monitoring in diseases such as POTS.
基金Supported by the National Natural Science Foundation of China (30972954)
文摘To investigate age and sex distribution of vasovagal syncope (VVS) patients undergoing head-up tilt table test (HUTT) at a tertiary hospital. The details of syncope patients who underwent HUTT at our department of cardiac function from January 2004 to December 2010 were reviewed. Of the 1 799 patients who underwent the HUTT, 854 tested positive, of which 558 (65.3%) were women, which were more than the women in the negative group (450, 47.6%) (p〈0.05). VVS patients showed a bimodal age distribution between 11 and 20 years of age and in the fourth decade. In almost all age groups, mixed response was the highest compared with vasodepressor and cardioinhibitory. VVS patients who underwent HUTT indicate bimodal distribution peaking before the second decade and the fourth decade. The incidence of females was twice that of males before the sixth decade, and old age occupies a small percentage of VVS with no other comorbidities.