Quantitative Assessment of Coronary Flow Reserve by the Variables of Time-Intensity Curve with Myocardial Contrast Echocardiography

The reliability and reliable indexes of q ua ntitative assessment of coronary flow reserve (CFR) by using time intensity cur ve (TIC) via myocardial contrast echocardiography were investigated. The TIC var iables were obtained by employing acoustic densitometry (AD) technique before an d after acetylcholine (Ach) injection in 12 dogs. Meanwhile, the correlation be tween these variables and CFR was analyzed. Among the variables derived from TIC , peak intensity (PI), area under the curve (AUC) and descending slope (DS) were increased significantly ( P <0.05) with the increase of coronary blood flow a fter Ach injection. Conversely, time to peak (TP), half time of descent (HT) , and mean transit time (MTT) were decreased remarkably ( P <0.0001). Th e P I and AUC ratios from post to pre Ach injection were strongly associated with CFR with the correlation coefficient (r) being 0.8366 and 0.8824, respectively. It is reliable by using the variables derived from TIC with myocardial contrast echocardiography to quantitatively evaluate regional myocardial CFR. The PI an d AUC ratios from post to pre Ach injection are the reliable indexes for quan titative assessment of CFR.

Effect on Intensity Correlation Time by Input Signal in a Single-Mode Laser with Bias Signal Modulation

The effect on intensity correlation time T by input signal is studied for gain-noise model of a single-mode laser driven by colored pump noise and colored quantum noise with colored cross-correlation with a bias signal modulation in this paper. By using the linear approximation method, we detect that there exists maximum （i.e., resonance） in the curve of the intensity correlation time T upon bias current io when the noise correlation coefficient λ is positive; and there exists minimum （i.e., suppression） in the T-io curve when λ is negative. And whenλ is zero, T increases monotonously with increasing io. Furthermore, the curve of T upon the signal frequency Ω is also studied. Our study shows that no matter what the value of λ is, there exists minimum （i.e., suppression） in the T-Ω curve.

Discussion on the feature of strong earthquake: Orderly distribution in time, space and intensity before the Western Kunlun Mountain Pass M=8.1 earthquake

In the paper, the feature of strong earthquake orderly distribution in time, space and intensity before the Western Kunlun Mountain Pass M=8.1 earthquake is preliminarily studied. The modulation and triggering factors such as the earth rotation, earth tides are analyzed. The results show that: the giant earthquakes with the magnitude more than 8 occurred about every 24 years and the earthquakes with the magnitude more than 7 about every 7 years in Chinese mainland. The Western Kunlun Mountain M=8.1 earthquake exactly occurred at the expected time; The spatial distance show approximately the same distances between each two swarms. The earth rotation, earth tide, sun tide and sun magnetic field have played a role of modulation and triggering in the intensity. At last, the condi-tions for earthquake generation and occurrence are also discussed.

Semiclassical and Quantum-Mechanical Formalism Applied in Calculating the Emission Intensity of the Atomic Hydrogen

The energy spectrum of the hydrogen atom has been applied in calculating the time rate of energy transitions between the quantum states of the atom. The formal basis of the approach has been provided by the quantum properties of energy and time deduced from the Joule-Lenz law. The rates of the energy transitions obtained in this way were compared with the quantum-mechanical probabilities of transitions calculated earlier by Bethe and Condon and Shortley for the same pairs of the quantum states.

Usefulness of dynamic contrast-enhanced MR imaging in the evaluation of pulmonary isolated lesions

Objective： The aim of our study was to investigate the value of dynamic contrast-enhanced MRI for evaluating differential diagnosis of pulmonary isolated lesions. Methods： Twenty-nine consecutive patients enrolled in this study, all of whom underwent DCE-MRI examinations and received a histologic and clinical diagnosis. Among these, lung tuberculoma 7 cases, harmatoma 3 cases, peripheral lung cancer 19 cases. DCE-MRI was acquired with 3D LAVA technique, total 18 phases were acquired, scanner time of per phase was 5-7″. After contrasting agent, twice successive scanning was acquired at 10″ and 50″. Then 1′30″, 2′, 2′30″, 3′, 3′30″, 4′, 5′, 6′, 7′, 8′, 9′, 10′, 11′, 12′ performed scanning. Region of interest was placed on the Maximum level in the tumors. According to Schaefer＇s standard, four types of time signal intensity curve （TIC） were classified, which were A, B, C and D. Compared the dynamic parameters between benign and malignant nodules. Results： Lung tuberculoma may display three curves： A type 1 case, ring-shaped enhancement 4 cases （periphery ring A type, central region D type）, D type 2 cases. Harmatoma may display three curves： A type 1 case, C type 2 case. Peripheral lung cancer may display A type. Except 2 cases D type lung tuberculoma, we compared curve data of 8 cases benign nodules （including tuberculoma Atype and periphery ring Atype, harmatoma Atype and C type） and lung cancer. SlEP%： benign nodules 0.7885 ±0.5543, lung cancer 1.2623 ±0.3059, P 〈 0.05; MER： benign nodules 1.0007 ± 0.4251, lung cancer 1.3694 ±0.2740, P 〈 0.05; washout： P 〉 0.05. Conclusion： Lung MR imaging is helpful to diagnosis and differential diagnosis of isolated benign and malignant nodules. SIEP% and MER could offer valuable information. The evolution of global tuberculosis may be from A type to ring-shaped ennoblement to D type. It was easy to do right diagnosis to lung tuberculoma with ring-shaped ennoblement and D type. Peripheral lung cancer commonly displayed A type and needed identification with acute inflammation. So, it is important to anti-inflammatory follow-up for a few A type nodules.

A Double Shot Noise Process and Its Application in Insurance

The authors consider a compound Cox model of insurance risk with the additional economic assumption of a positive interest rate. As the authors note a duality result relating a compound Cox model of insurance risk with a positive interest rate and a double shot noise process, the authors analyze a double shot noise process systematically for its theoretical distributional properties, based on the piecewise deterministic Markov process theory, and the martingale methodology. The authors also obtain the moments of aggregate accumulated/discounted claims where the claim arrival process follows a Cox process with shot noise intensity. Removing the parameters in a double shot noise process gradually, the authors show that it becomes a compound Cox process with shot noise intensity, a single shot noise process and a compound Poisson process. Numerical comparisons are shown between the moments （i.e. means and variances） of a compound Poisson model and their counterparts of a compound Cox model with/without considering a positive interest rate. For that purpose, the authors assume that claim sizes and primary event sizes follow an exponential distribution, respectively.

The statistical fluctuation of a single-mode laser system driven by coloured pump noise with signal modulation and the quantum noise with cross-correlation between its real and imaginary parts

Using the linear approximation method, this paper studies the statistical property of a single-mode laser driven by both coloured pump noise with signal modulation and the quantum noise with cross-correlation between its real and imaginary parts, and calculates the steady-state mean normalized intensity fluctuation and intensity correlation time. It analyses the influences of the modulation signal, the net gain coefficient, the noise and its correlation form on the statistical fluctuation of the laser system respectively. It is found that the coloured pump noise modulated by the signal has a great suppressing action on the statistical fluctuation of the laser system; the pump noise self-correlation time and the specific frequency of modulation signal have the result that the statistical fluctuation tends to zero. Furthermore, the ＇colour＇ correlation of pump noise has much influences on the statistical fluctuation of the laser system. Increasing the intensity of pump noise will augment the statistical fluctuation of the laser system, but the intensity of quantum noise and the coefficient of cross-correlation between its real and imaginary parts have less influence on the statistical fluctuation of the laser system. Therefore, from the conclusions of this paper the statistical property can be known and a theoretical basis for steady operation and output of the laser system can be provided.

On the refracted patterns produced by liquid vortices

A theoretical analysis of the refracted shadows produced by steady and time-decaying liquid vortices under uniform illumination from above is given in this article. An expression for the induced shadow intensity is derived and found to be a function of the vortex＇s free surface profile, i.e., function of the static pressure distribution. The patterns for different focusing depth are given and compared with previous visualization results from the literature. The phenomenon is examined and illustrated as a bench mark case by using both steady and time-decaying algebraic vortex models. However, this study can be extended to check the feasibility of recovering the main flow properties by analyzing the luminous image intensity of the refracted patterns. The present analysis is valid only when the swirl velocity is order of magnitude higher than the meridional flow components and the vorticity is concentrated within the core region and of intense conditions.

A Novel Criterion of Mixing Time in Gas-Stirred Ladle Systems

A novel criterion of mixing time in gas-stirred ladle systems was proposed in this paper. The essential difference between the previous criterion and the present one is that the former is based on the concentration itself while the latter is based on the variation rate of the concentration, which reflects the mixing efficiency directly. Experiment was carried out in an acrylic glass vessel with bottom blowing, and the tracer concentration was monitored by electrical conductivity probes. The mixing time obtained through the new criterion is approximately 20% less than that obtained through the 95% criterion, and the deviations of mixing times calculated from the new criterion are smaller than that from the previous one under the same conditions.

Time development of surface enhanced Raman intensities of the adsorbed pyrazine molecules on the silver electrode as the applied voltage varies

In this work,the time development of surface enhanced Raman intensities of the vibrational modes involving the ring skeleton and the C—H motions of the pyrazine molecule as the applied voltage on the silver electrode is shifted between -0.2 V and -0.5 V (vs.saturated calomel electrode)is reported.The observation shows that there are two processes of enhancement involved during this shift of applied voltage.One is vibrational mode dependent while the other is not.The detailed behavior of these two processes of enhancement is discussed along with the retarded response of the Helmholtz double layer structure to the change of the applied voltage on the electrode.