The fundamental aspects of The Timed-Release Analysis (TRA) and some problems are analysed. Having studied the attribute of optimum flotation test results and the way of optimum test conditions, the auther put forward...The fundamental aspects of The Timed-Release Analysis (TRA) and some problems are analysed. Having studied the attribute of optimum flotation test results and the way of optimum test conditions, the auther put forward a proposal to improve this test method by adding a new test step of scavenging flotation and using optimum test conditions varied with different fine coals instead of the given ones settled by the TRA norm. Comparison between test results of the two methods of TRA shows that the improved method is very good.展开更多
In this investigation, the effect of formulation variables on the release properties of timed- release press-coated tablets was studied using the Taguchi method of experimental design. Formulations were prepared based...In this investigation, the effect of formulation variables on the release properties of timed- release press-coated tablets was studied using the Taguchi method of experimental design. Formulations were prepared based on Taguchi orthogonal array design with different types of hydrophilic polymers (X1), varying hydrophilic polymer/ethyl cellulose ratio (X2), and addition of magnesium stearate (X3) as independent variables. The design was quantitatively evalu-ated by best fit mathematical model. The results from the statistical analysis revealed that factor X1, X3 and interaction factors between X1X2 and X1X3 were found to be significant on the re-sponse lag time (Y1), where as only factor X1 was found to be significant on the response percent drug release at 8 hrs (Y2). A numerical optimization technique by desirability function was used to optimize the response variables, each having a different target. Based on the re-sults of optimization study, HPC was identified as the most suitable hydrophilic polymer and incorporation of hydrophobic agent magnesium stearate, could significantly improve the lag time of the timed-release press-coated tablet.展开更多
Despite the benefits of EHRs (Electronic Health Records), there is a growing concern over the risks of privacy exposure associated with the technologies of EHR storing and transmission. To deal with this problem, a ti...Despite the benefits of EHRs (Electronic Health Records), there is a growing concern over the risks of privacy exposure associated with the technologies of EHR storing and transmission. To deal with this problem, a timeaware searchable encryption with designated server is proposed in this paper. It is based on Boneh's public key encryption with keyword search and Rivest's timed-release cryptology. Our construction has three features: the user cannot issue a keyword search query successfully unless the search falls into the specific time range;only the authorized user can generate a valid trapdoor;only the designated server can execute the search. Applying our scheme in a multi-user environment, the number of the keyword ciphertexts would not increase linearly with the number of the authorized users. The security and performance analysis shows that our proposed scheme is securer and more efficient than the existing similar schemes.展开更多
On the basis of the float-and-sink analysis and the timed-release analysis, a new theoretical floatability curve of coal has been advanced. By means of fitting to a lot of data, a model of theoretical floatability cur...On the basis of the float-and-sink analysis and the timed-release analysis, a new theoretical floatability curve of coal has been advanced. By means of fitting to a lot of data, a model of theoretical floatability curve has been set up. The characteristics of curve and how to achieve standardization were discussed.展开更多
文摘The fundamental aspects of The Timed-Release Analysis (TRA) and some problems are analysed. Having studied the attribute of optimum flotation test results and the way of optimum test conditions, the auther put forward a proposal to improve this test method by adding a new test step of scavenging flotation and using optimum test conditions varied with different fine coals instead of the given ones settled by the TRA norm. Comparison between test results of the two methods of TRA shows that the improved method is very good.
文摘In this investigation, the effect of formulation variables on the release properties of timed- release press-coated tablets was studied using the Taguchi method of experimental design. Formulations were prepared based on Taguchi orthogonal array design with different types of hydrophilic polymers (X1), varying hydrophilic polymer/ethyl cellulose ratio (X2), and addition of magnesium stearate (X3) as independent variables. The design was quantitatively evalu-ated by best fit mathematical model. The results from the statistical analysis revealed that factor X1, X3 and interaction factors between X1X2 and X1X3 were found to be significant on the re-sponse lag time (Y1), where as only factor X1 was found to be significant on the response percent drug release at 8 hrs (Y2). A numerical optimization technique by desirability function was used to optimize the response variables, each having a different target. Based on the re-sults of optimization study, HPC was identified as the most suitable hydrophilic polymer and incorporation of hydrophobic agent magnesium stearate, could significantly improve the lag time of the timed-release press-coated tablet.
基金This study was jointly supported by the National Natural Science Foundation of China (No. 61702067, No. 61472464)the Natural Science Foundation of Shangdong Province, China (No. ZR2015FL024).
文摘Despite the benefits of EHRs (Electronic Health Records), there is a growing concern over the risks of privacy exposure associated with the technologies of EHR storing and transmission. To deal with this problem, a timeaware searchable encryption with designated server is proposed in this paper. It is based on Boneh's public key encryption with keyword search and Rivest's timed-release cryptology. Our construction has three features: the user cannot issue a keyword search query successfully unless the search falls into the specific time range;only the authorized user can generate a valid trapdoor;only the designated server can execute the search. Applying our scheme in a multi-user environment, the number of the keyword ciphertexts would not increase linearly with the number of the authorized users. The security and performance analysis shows that our proposed scheme is securer and more efficient than the existing similar schemes.
文摘On the basis of the float-and-sink analysis and the timed-release analysis, a new theoretical floatability curve of coal has been advanced. By means of fitting to a lot of data, a model of theoretical floatability curve has been set up. The characteristics of curve and how to achieve standardization were discussed.
