电针听会、本神穴联合康复训练治疗精神发育迟滞患儿的临床效果

目的观察电针听会、本神穴联合康复训练治疗精神发育迟滞患儿的临床效果。方法选取2022年6月至2023年6月龙岩市中医院收治的60例精神发育迟滞患儿作为研究对象,按照随机数字法分为观察组(30例)与对照组(30例)。观察组采用先予电针听会、本神穴后予康复训练方法,对照组采用康复训练方法。比较两组韦氏幼儿智力量表、S-S语言发育迟缓检查量表,Gesell发育量表评分,并评价疗效。结果治疗后,观察组总智商、言语理解评分高于对照组,差异有统计学意义(P<0.05)。治疗后,观察组语言能力及基本学习能力正常例数、交流态度良好例数均高于对照组,差异有统计学意义(P<0.05)。治疗后,观察组适应性行为、精细动作、大运动、语言行为、个人-社交发育商评分均高于对照组,差异有统计学意义(P<0.05)。观察组总有效率高于对照组,差异有统计学意义(P<0.05)。结论电针听会、本神穴可有效提高精神发育迟滞患儿语言功能,改善认知水平,促进神经发育,值得临床推广。

调神复聪针法治疗桥小脑区梗死致感音神经性耳聋

目的评价调神复聪针法治疗桥小脑区梗死致感音神经性耳聋的临床疗效。方法选取桥小脑区梗死致感音神经性耳聋患者60例,将其随机分为治疗组和对照组,各30例,治疗组采用调神复聪针法治疗,对照组施以传统针刺治疗,疗程为14 d,采用听力测定及BAEP为主要评价指标,于治疗前后进行组内比较和疗后组间比较。结果 2组患者经不同针法治疗后,治疗组总有效率为88.89%,优于对照组总有效率65.38%(P<0.05);2组患者治疗后BAEP中各分项评分均有改善,而治疗组对听力及脑干听觉诱发电位的改善程度明显优于对照组(P<0.05)。结论调神复聪针法治疗桥小脑区梗死致感音神经性耳聋疗效确切,可明显改善脑干听觉诱发电位,提高患者的听力水平。

庄礼兴教授针灸治疗感音神经性耳聋经验

介绍庄礼兴教授针灸治疗感音神经性耳聋的经验。感音神经性耳聋是临床常见难治性疾病,主要表现为单侧或双侧耳部不同程度的渐进性听力减退直至耳聋,目前本病病因及发病机制尚不明确。庄礼兴教授提出对本病的论治应以局部开通气闭、循经畅通气机为主,强调深刺听会穴以得气;衷中参西,针刺晕听区刺激听觉中枢;辨经取穴与局部取穴相结合,灵活运用多种针法,临床疗效显著,经验值得借鉴。

针刺治疗椎-基底动脉供血不足疗效观察

目的观察针刺项后9穴为主治疗椎-基底动脉供血不足的临床疗效。方法将100例椎-基底动脉供血不足患者随机分为治疗组和对照组,每组50例。治疗组采用针刺风府、风池、完骨、天柱、C3夹脊穴治疗,对照组采用口服尼莫地平片治疗。观察两组治疗前后TCD各项指标及眩晕评定量表的评分系统(DARS)平均评分,并比较两组临床疗效。结果治疗组治疗后TCD各项指标与同组治疗前比较,差异均具有统计学意义(P<0.05)。对照组治疗后TCD相关指标[Vs(RVA)、Vd(BA、LVA)、Vm(BA、RVA)、PI(BA)]与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗后TCD相关指标[Vs(BA、LVA、RVA)、Vd(BA、RVA)、Vm(BA、LVA)、PI(BA)]与对照组比较,差异均具有统计学意义(P<0.05)。两组治疗7 d后DARS平均评分与同组治疗前比较,差异均具有统计学意义(P<0.01)。两组治疗后DARS平均评分与同组治疗7 d后比较,差异均具有统计学意义(P<0.01)。治疗组治疗7 d后及治疗后DARS平均评分与对照组比较,差异均具有统计学意义(P<0.01)。治疗组愈显率和总有效率分别为76.0%和98.0%,对照组分别为44.0%和96.0%。两组愈显率比较,差异具有统计学意义(P<0.05)。结论针刺项后9穴是一种治疗椎-基底动脉供血不足的有效方法。

Influence of acupoint-injection on TXB_2 and 6-keto-PGF_(1a) in patients with pseudobulbar palsy: a randomized controlled trial

Objective： To prove the feasibility and validity of Xing Nao Jing acupoint-injection （XNJ-AI） at Fengchi （GB 20） for pseudobulbar palsy caused by ischemic stroke （PBP-IS）. Methods： An assessor-blinded, two-parallel-group, randomized controlled trial was conducted, and the patients with PBP-IS were recruited and randomly divided into two groups. Patients in the control group received oral aspirin （100 mg per day for 2 weeks）. In addition to oral aspirin; patients in the treatment group received XNJ-AI at Fengchi （GB 20）, once a day, for two weeks. The primary outcome was assessed by the water-swallowing test （WST）. Thromboxane B2 （TXB2） and 6-keto-prostaglandin F1α （6-keto-PGF1α） in plasma were measured before and after the treatment. Results： In the treatment group, the percentage of swallowing function no less than grade 3 before and after the treatment was 32% and 88%, respectively; in the control group, it was 28% and 76% before and after the treatment, respectively; the difference after the treatment between the two groups was statistically significant （P〈0.05）. There were statistical differences between pre- and post-treatment levels of plasma TXB2 and 6-keto-PGF1α in the two groups （both P〈0.05）. After the treatment, there were significant differences in the levels of plasma TXB2 and 6-keto-PGF1α between the two groups （both P〈0.05）. Conclusion： XNJ-AI at Fengchi （GB 20） can improve the patients＇ swallowing function and balance the levels of TXB2 and 6-keto-PGF1α in plasma.

Effect of electroacupuncture on JAK2/STAT3 pathway in synovial tissues of rats with rheumatoid arthritis

Objective: To observe the effect of electroacupuncture (EA) on Janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) pathway in knee joint synovial tissues of rats with rheumatoid arthritis (RA) and to explore the action mechanism of EA on RA. Methods: Twelve of the 48 SPF male Sprague-Dawley (SD) rats were assigned to a normal group by the random number table method. The remaining 36 rats were subjected to RA model preparation by intradermal injection of the Freund's complete adjuvant into the right hind foot pad of each rat under sterile conditions. After the model was successfully prepared, rats were then divided into a model group, a drug group and an EA group according to a random number table method (n=12). Rats in the drug group were treated with 2 mL aqueous solution of tripterygium glycosides [8.1 mg/(kg?bw)];rats in the EA group were treated with EA at bilateral Yanglingquan (GB 34) and Zusanli (ST 36), for 30 min each time;rats in the normal group and the model group were placed in a special rat fixation tank for 30 min each time, and received the same dose of normal saline as those in the drug group. Rats in all groups received intervention once a day for 4 weeks. Diameter of rat ankle joint and rat arthritis index were measured before and after the intervention. At the end of the experiment, the expressions of phospho-JAK2 and phospho-STAT3 were determined by immunohistochemistry. Quantitative real-time polymerase chain reaction (RT-qPCR) was used to detect JAK2 and STAT3 mRNAs expressions. Results: After the model was produced, the arthritis index >2 was considered successful in model preparation. Compared with the model group, the ankle joint diameters and arthritis indexes of rats in the drug group and the EA group were significantly lower (all P<0.01);immunohistochemical staining cells with phospho-JAK2 and phospho-STAT3 were significantly decreased (all P<0.01);the expression levels of JAK2 and STAT3 mRNAs were decreased with statistical differences (all P<0.01). There were no significant differences between the EA group and the drug group (all P>0.05). Conclusion: EA can alleviate the inflammatory response of RA rats, improve their pathological conditions, reduce the expressions of phospho-JAK2 and phospho-STAT3 in the synovial tissue of knee joint, and decrease the expressions of JAK2 and STAT3 mRNAs. The therapeutic effect of EA is comparable to that of the tripterygium glycosides. The mechanism of EA treatment may be related to the inactivation of the JAK2/STAT3 pathway.

电针听会、本神对孤独症谱系障碍患儿听觉反应异常的影响

目的:比较电针听会、本神联合常规康复训练与单纯常规康复训练对孤独症谱系障碍(ASD)患儿听觉反应异常的影响。方法:将70例ASD患儿随机分为观察组和对照组,每组35例。对照组采用常规康复训练治疗;观察组在对照组基础上予电针听会、本神(疏密波,频率2 Hz/10 Hz)治疗,每次20 min,治疗6 d后休息1d,两组均连续治疗12周。比较两组患儿治疗前后听觉反应异常发生率及儿童孤独症评定量表(CARS)、孤独症行为量表(ABC)评分。结果:治疗后,两组患儿听觉反应异常总发生率及观察组患儿听觉反应迟钝、听觉反应过敏发生率均较治疗前降低(P<0.05),观察组患儿听觉反应异常总发生率及听觉反应过敏发生率低于对照组(P<0.05)。治疗后,两组患儿CARS、ABC评分均较治疗前降低(P<0.05),且观察组低于对照组(P<0.05)。结论:电针听会、本神联合常规康复训练可降低ASD患儿听觉反应异常发生率,改善ASD患儿核心症状,临床疗效优于单纯常规康复训练。

Observation on clinical effects of acupuncture plus cupping therapy for cervical radiculopathy

Objective：To observe the therapeutic effects of acupuncture plus cupping therapy and Western medication alone for cervical radiculopathy.Methods：A total of 139 patients with cervical radiculopathy were randomly divided based on the random digital table into an acupuncture-cupping group（70 cases） and a Western medication group（69 cases）.In the acupuncture-cupping group,Fengchi（GB 20）（bilateral）,Dazhui（GV 14）,Jianjing（GB 21）（bilateral） and Jiaji（EX-B 2） points of the neck [bilateral,midpoint between Fengchi（GB 20） and Dazhui（GV 14）] were punctured.After the arrival of the needling sensation,bilateral Fengchi（GB 20） and Jianjing（GB 21） were linked with electric stimulation and the rest acupoints were manipulated with the moderate needling technique.In the retaining of the needles,TDP lamp radiation was used.After acupuncture,the cupping therapy was applied to the local area.The treatment was given once every other day,20 d for a course.After one course,the therapeutic effects were observed.The Western medication group was treated by oral administration of Meloxicam（Mobic）,7.5 mg,once a day,with water and liquid after meal.The therapeutic effects were observed after 20 d.Results：The total effective rate was 92.8% in the acupuncture-cupping group and 73.9% in the Western medication group,with a statistical difference between the two groups（P〈0.05）.After treatment,the scores of the clinical symptoms of the two groups were obviously declined（P〈0.01）,and the score of the clinical symptoms of the acupuncture-cupping group was better than that of the Western medication group,with a statistical difference（P〈0.05）.Conclusion：Acupuncture plus cupping therapy was more effective than administration of Meloxicam tablets alone in the treatment of cervical radiculopathy.