Allowable levels for pesticide residues in foods,known as tolerances in the US and as maximum residue limits(MRLs) in much of the world,are widely yet inappropriately perceived as levels of safety concern. A novel app...Allowable levels for pesticide residues in foods,known as tolerances in the US and as maximum residue limits(MRLs) in much of the world,are widely yet inappropriately perceived as levels of safety concern. A novel approach to develop scientifically defensible levels of safety concern is presented and an example to determine acute and chronic pesticide food safety standard(PFSS) levels for the fungicide captan on strawberries is provided. Using this approach,the chronic PFSS level for captan on strawberries was determined to be 2 000 mg kg–1 and the acute PFSS level was determined to be 250 mg kg–1. Both levels are far above the existing tolerance and MRLs that commonly range from 3 to 20 mg kg–1,and provide evidence that captan residues detected at levels greater than the tolerance or MRLs are not of acute or chronic health concern even though they represent violative residues. The benefits of developing the PFSS approach to serve as a companion to existing tolerances/MRLs include a greater understanding concerning the health significance,if any,from exposure to violative pesticide residues. In addition,the PFSS approach can be universally applied to all potential pesticide residues on all food commodities,can be modified by specific jurisdictions to take into account differences in food consumption practices,and can help prioritize food residue monitoring by identifying the pesticide/commodity combinations of the greatest potential food safety concern and guiding development of field level analytical methods to detect pesticide residues on prioritized pesticide/commodity combinations.展开更多
Despite the large size of most communication and transportation systems,there are short paths between nodes in these networks which guarantee the efficient information,data and passenger delivery;furthermore these net...Despite the large size of most communication and transportation systems,there are short paths between nodes in these networks which guarantee the efficient information,data and passenger delivery;furthermore these networks have a surprising tolerance under random errors thanks to their inherent scale-free topology.However,their scale-free topology also makes them fragile under intentional attacks,leaving us a challenge on how to improve the network robustness against intentional attacks without losing their strong tolerance under random errors and high message and passenger delivering capacity.Here we propose two methods (SL method and SH method) to enhance scale-free network's tolerance under attack in different conditions.展开更多
基金the Chilean Government and the National Commission for Scientific and Technological Research (CONICYT) for supporting this work through the Becas Chile Scholarships
文摘Allowable levels for pesticide residues in foods,known as tolerances in the US and as maximum residue limits(MRLs) in much of the world,are widely yet inappropriately perceived as levels of safety concern. A novel approach to develop scientifically defensible levels of safety concern is presented and an example to determine acute and chronic pesticide food safety standard(PFSS) levels for the fungicide captan on strawberries is provided. Using this approach,the chronic PFSS level for captan on strawberries was determined to be 2 000 mg kg–1 and the acute PFSS level was determined to be 250 mg kg–1. Both levels are far above the existing tolerance and MRLs that commonly range from 3 to 20 mg kg–1,and provide evidence that captan residues detected at levels greater than the tolerance or MRLs are not of acute or chronic health concern even though they represent violative residues. The benefits of developing the PFSS approach to serve as a companion to existing tolerances/MRLs include a greater understanding concerning the health significance,if any,from exposure to violative pesticide residues. In addition,the PFSS approach can be universally applied to all potential pesticide residues on all food commodities,can be modified by specific jurisdictions to take into account differences in food consumption practices,and can help prioritize food residue monitoring by identifying the pesticide/commodity combinations of the greatest potential food safety concern and guiding development of field level analytical methods to detect pesticide residues on prioritized pesticide/commodity combinations.
基金Project supported in part by the China Scholarships Council (Grant No. 2007103794)the Defence Threat Reduction Agency Award HDTRA1-08-1-0027+5 种基金the James S. McDonnell Foundation 21st Century Initiative in Studying Complex Systems,the National Science Foundation within the DDDAS (CNS-0540348)ITR (DMR-0426737)IIS-0513650 programsthe US Office of Naval Research Award N00014-07-Cthe National Natural Science Foundation of China (Grant Nos. 80678605 and 60903157)the National High Technology Research and Development Program of China (Grant No. 2009AA01Z422)
文摘Despite the large size of most communication and transportation systems,there are short paths between nodes in these networks which guarantee the efficient information,data and passenger delivery;furthermore these networks have a surprising tolerance under random errors thanks to their inherent scale-free topology.However,their scale-free topology also makes them fragile under intentional attacks,leaving us a challenge on how to improve the network robustness against intentional attacks without losing their strong tolerance under random errors and high message and passenger delivering capacity.Here we propose two methods (SL method and SH method) to enhance scale-free network's tolerance under attack in different conditions.
