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肝脏转移瘤的CT分析
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作者 祝玉芬 薛春华 +1 位作者 国平英 李成明 《解放军医药杂志》 CAS 1995年第3期167-168,242,共3页
本文分析65例肝转移瘤的CT表现,其中25例为坏死性肝转移瘤。指出肝转移瘤CT表现以病灶多发及部分瘤体中心圆形坏死为特点,此特征亦是肝转移瘤与原发性肝癌的主要鉴别点。下文还讨论了肝转移瘤与原发灶的关系及其与肝脓肿的鉴别诊断问题。
关键词 肝Liver 肿瘤转移Metastases X线计算机断层摄影术X-ray COMPUTED tomograpby
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Procoagulant activity of circulating microparticles is associated with the presence of moderate calcified plaque burden detected by multislice computed tomography 被引量:1
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作者 Serena Del Turco Giuseppina Basta +6 位作者 Alessandro Mazzarisi Debora Battaglia Teresa Navarra Michele Coceani Massimiliano Bianchi Mathis Schlueter Paolo Marraccini 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2014年第1期13-19,共7页
Background Circulating microparticles (MPs) have been reported to be associated with coronary artery disease (CAD). In this study, we explored the relationship between MPs procoagulant activity and characteristics... Background Circulating microparticles (MPs) have been reported to be associated with coronary artery disease (CAD). In this study, we explored the relationship between MPs procoagulant activity and characteristics of atherosclerotic plaque detected by 64-slice computed tomography angiography (CTA). Methods In 127 consecutive patients with CAD but without acute coronary syndrome and who under went 64-slice CTA, MPs procoagulant activity in plasma Coy a thrombin generation test), soluble form of lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1) and N(epsilon)-(carboxymethyl) lysine (CML) circulating levels (by ELISA) were measured. A quantitative volumetric analysis of the lumen and plaque burden of the vessel wall (soft and calcific components), for the three major coronary vessels, was performed. The patients were classified in three groups according to the presence of calcium volume: non-calcified plaque (NCP) group (calcium volume (%) = 0), moderate calcified plaque (MCP) group (0 〈 calcium volume (%) 〈 1), and calcified plaque (CP) group (calcium volume (%) 〉 1). Results MPs procoagulant activity and CML levels were higher in MCP group than in CP or NCP group (P = 0.009 and P = 0.027, respectively). MPs procoagulant activity was positively associated with CML (r = 0.317, P 〈 0.0001) and sLOX-1 levels (r = 0.216, P = 0.0025). Conclusions MPs procoagulant activity was higher in the MCP patient group and correlated positively with sLOX-1 and CML levels, suggesting that it may characterize a state of blood vulnerability that may locally precipitate plaque instability and increase the risk of subsequent major cardiovascular events. 展开更多
关键词 Computed tomograpby Micropanicles Low density lipoprotein LYSINE Coronary artery disease
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