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An Improved Method for the Sy nthesis of Optically Active Tomoxetines and Fluoxetines
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作者 徐成富 袁承业 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2004年第8期775-778,共4页
A chemoenzymatic approach was applied to the preparation of chiral 3-hydroxy-3-arylpropionates and 3-hydroxy-4,4,4-trifluorobutanoate that are potential precursors for certain chiral pharmaceuticals including chiral ... A chemoenzymatic approach was applied to the preparation of chiral 3-hydroxy-3-arylpropionates and 3-hydroxy-4,4,4-trifluorobutanoate that are potential precursors for certain chiral pharmaceuticals including chiral tomoxetines and fluoxetines. 展开更多
关键词 hydroxy-3-arylpropionate 3-hydroxy-4 4 4-trifluorobutanoate Candia rugosa lipase (CRL) tomoxetine FLUOXETINE
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