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Regulating and tonifying spleen and kidney traditional Chinese medicine in the treatment of chronic uric acid nephropathy: A systematic review
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作者 Yuan-Ping Jia Xuan-Zhi Wang +2 位作者 Shi-Xiang Niu Yan-Tong Deng Hong-Chun Zhang 《Journal of Hainan Medical University》 2021年第22期52-52,共1页
Objective:To systematically evaluate the efficacy and safety of traditional Chinese medicine for regulating spleen and kidney.Methods:We developed a search strategy and then retrieved the database including CNKI,Wanfa... Objective:To systematically evaluate the efficacy and safety of traditional Chinese medicine for regulating spleen and kidney.Methods:We developed a search strategy and then retrieved the database including CNKI,Wanfang data knowledge service platform,VIP journals resource integration service platform,PubMed,Embasefor randomized controlled trial of regulating spleen and kidney traditional Chinese medicine compared with conventional western medicine in the treatment of chronic uric acid nephropathy.The search deadline was set to June 30,2020.For the included literature,we applied the cochrane collaboration network risk bias assessment tool to evaluate the methodological quality,and evaluated the level of evidence according to GRADE standards.Quantitative data was analyzed by RevMan5.3 software,and trial sequential analysis method was used to analyze its efficiency.Results:A total of 709 cases in 10 articles were included.Compared with the control group,the related traditional Chinese medicine group improved the effective rate[RR=1.45,95%CI(1.32,1.58)],reduced the level of UA[MD=-36.24,95%CI(-41.03,-31.45)],BUN[SMD=-1.27,95%CI(-1.47,-1.07)]and SCR[MD=-36.33,95%CI(-55.79,-16.87),P=0.0003],the difference between the two groups was statistically significant(P<0.05).There was no evidence that a significant adverse reaction occurred.The results of TSA analysis showed that the Chinese medicine group had definite evidence for improving the efficiency.According to the GRADE evaluation criteria,the efficiency,UA,BUN and SCR outcome indicators were extremely low-quality evidence.Conclusions:Traditional Chinese medicine for regulating spleen and kidney in the treatment of chronic uric acid nephropathy improved efficiency,reduced the level of UA,BUN,SCR.Meanwhile,the therapy was proved to be safe.Nevertheless,the conclusions need further high-quality evidence to support. 展开更多
关键词 Regulating and tonifying spleen and kidney therapy TCM Uric acid nephropathy GRADE classification
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Theoretical Discussion on Treatment of Cubital Tunnel Syndrome Based on Theory of Liver,Spleen and Kidney
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作者 ZHANG Xiao-li SU Xiao-lei +3 位作者 DU Xuan-xuan WANG Zi-yu LI Jun-jie YU Hang 《World Journal of Integrated Traditional and Western Medicine》 2022年第4期22-28,共7页
Cubital tunnel syndrome is a disease in which ulnar nerve is compressed by its surrounding tissues,and its main clinical manifestations are pain,sensory disturbance and dyskinesia.Its incidence rate is the second high... Cubital tunnel syndrome is a disease in which ulnar nerve is compressed by its surrounding tissues,and its main clinical manifestations are pain,sensory disturbance and dyskinesia.Its incidence rate is the second highest among peripheral nerve entrapment diseases,and it is one of the common clinical diseases.The theory of liver,spleen and kidney can guide the treatment of cubital tunnel syndrome with traditional Chinese medicine and acupuncture.By discussing the traditional Chinese medicine(TCM)pathogenesis and treatment principles of cubital tunnel syndrome,it provides modern medical theoretical support for TCM treatment of cubital tunnel syndrome. 展开更多
关键词 Cubital tunnel syndrome Soothing the liver Regulating the spleen kidney tonifying
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Research Progress on Chemical Constituents and Pharmacological Effect of Semen Cuscutae
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作者 Zhuola Chunhui LIU 《Medicinal Plant》 CAS 2021年第1期12-15,共4页
In this paper,by summarizing the literature in recent years,it is considered that the chemical constituents of S.cuscutae are mainly flavonoids.The main pharmacological effects include improving osteoporosis,improving... In this paper,by summarizing the literature in recent years,it is considered that the chemical constituents of S.cuscutae are mainly flavonoids.The main pharmacological effects include improving osteoporosis,improving ovarian function,improving drug-induced reproductive toxicity,regulating spermatogenic cell apoptosis,resisting liver fibrosis,resisting inflammation,improving cardiovascular function,protecting fetus,protecting synapses and so on.By summarizing the chemical constituents and pharmacological effects of S.cuscutae,this study aims to better study the mechanism of anti-osteoporosis based on the fact that S.cuscutae has the function of tonifying liver and kidney. 展开更多
关键词 Semen Cuscutae Flavonoids from S.cuscutae Pharmacological effect tonifying liver and kidney
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Effectiveness of tonifying-kidney and regulating-liver therapy on diminished ovarian reserve: a systematic review and Meta-analysis of randomized controlled trials 被引量:6
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作者 Liu Liuqing Liu Yanfeng +5 位作者 Yang Ming Xu Guiqin Li Ruiqi Xu Xiuli Pan Xue Liang Jialing 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2020年第3期343-354,共12页
OBJECTIVE: To evaluate the effectiveness of the Traditional Chinese Medicine tonifying-kidney and regulating-liver therapy on diminished ovarian reserve(DOR).METHODS: The literature was comprehensively searched up to ... OBJECTIVE: To evaluate the effectiveness of the Traditional Chinese Medicine tonifying-kidney and regulating-liver therapy on diminished ovarian reserve(DOR).METHODS: The literature was comprehensively searched up to August 2019 using four Chinese and three English electronic databases to extract randomized clinical trials(RCTs) comparing Traditional Chinese Medicine tonifying-kidney and regulating-liver prescriptions(combined with hormone therapy or not) with Western Medicine. Data quality evaluation was conducted using the Cochrane risk of bias tool. Meta-analysis was conducted using Revman 5.3 software with effect estimates presented as mean difference(MD), risk ratio(RR), and95% confidence interval(CI).RESULTS: A total of nine RCTs with 512 participants were extracted and eligible for Meta-analysis.There were no significant differences between Chinese medicine and Western Medicine on basal serum follicle-stimulating hormone(FSH) level(MD0.11, 95% CI-0.52 to 0.74, 392 participants, seven trials), anti-Müllerian hormone level(MD 0.48, 95%CI-0.62 to 1.58, 95 participants, two trials), and the FSH and luteinizing hormone ratio(MD 0.01,95% CI-0.95 to 0.96, 115 participants, two trials).Chinese medicine was more effective at improving Traditional Chinese Medicine symptom scores(TCMSS)(MD-2.39, 95% CI-3.83 to-0.94, 160 participants, three trials), effective rate of TCMSS(RR1.18, 95% CI 1.02 to 1.36, 160 participants, three trials), antral follicle count(AFC)(MD 0.55, 95% CI 0.05 to 1.04, 155 participants, three trials), and FSH levels at 3 months post-treatment(MD-4.77, 95% CI-6.09 to-3.45, 137 participants, two trials).CONCLUSION: Compared with Western Medicine,tonifying-kidney and regulating-liver therapy is more effective at relieving symptoms and improving AFC and FSH at 3 months post-treatment. 展开更多
关键词 Ovarian reserve tonifying kidney and regulating liver Randomized controlled trial Systematic review META-ANALYSIS
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Determining the Electrical Conductivity of Rat Cadaveric Liver,Spleen,and Kidney to Estimate Early Postmortem Interval 被引量:3
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作者 Zhe Zheng Xiandun Zhai +1 位作者 Zhiyuan Xia Yaonan Mo 《Journal of Forensic Science and Medicine》 2017年第3期111-114,共4页
Previous research has found that electrical conductivity(EC),an important index to predict meat freshness and shelflife,is very promising for estimating the late postmortem interval(PMI).However,whether it has potenti... Previous research has found that electrical conductivity(EC),an important index to predict meat freshness and shelflife,is very promising for estimating the late postmortem interval(PMI).However,whether it has potential use in the early PMI has not been fully studied yet.To test this possibility in the present study,EC of three internal organs of rat liver,spleen,and kidney were determined within 24 postmortem hows,and then,EC changes at different PMIs were carefully analyzed.The overall results showed that EC of liver and spleen increased significantly with PMI while EC of kidney had minor changes during the same period.Specifically,significant linear positive correlations between EC of liver and spleen and PMI were found and the coefficients of their regression functions were R^(2)=0.98 and R^(2)=0.95,respectively.It can be concluded that determination of EC in certain internal organs such as liver and spleen may be a potential tool in the early PMI estimation.However,more researches on its influencing factors are needed to facilitate its final use in practice. 展开更多
关键词 Early postmortem interval electrical conductivity forensic science kidney liver spleen
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Tonifying Kidney, Lung, and Spleen Combined with Western Medicine for Stable Chronic Obstructive Pulmonary Disease: A Systematic Review 被引量:1
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作者 Ying-Ying Liu Zhen Gao 《World Journal of Traditional Chinese Medicine》 2019年第4期202-213,共12页
Introduction:This study aimed to evaluate the clinical effectiveness and safety of tonifying kidney,lung,and spleen(TKLS)combined with Western medicine for stable chronic obstructive pulmonary disease(COPD).Materials ... Introduction:This study aimed to evaluate the clinical effectiveness and safety of tonifying kidney,lung,and spleen(TKLS)combined with Western medicine for stable chronic obstructive pulmonary disease(COPD).Materials and Methods:Randomized controlled trials(RCTs)of TKLS for stable COPD were searched from four databases including Pub Med,the Cochrane Library,China Biology Medicine,and China National Knowledge Infrastructure from inception to December 2017.Two reviewers independently screened the literature,extracted the data,and assessed the risk of bias in the included studies.Rev Man5.3 software was used for meta-analysis.Results:Fourteen RCTs involving 1339 patients with stable COPD were included.Five of the included articles described the specific method of randomization,1 of them was double-blind method research,and 1 of them was single-blind method research.Compared with the conventional Western medicine(CWM)group,the use of TKLS,if combined with CWM demonstrated significantly improved effective rate(relative risk=1.25,95%confidence interval[CI]:1.18–1.33,P<0.00001),decreased traditional Chinese medicine syndrome score(mean difference[MD]-5.72,95%CI:-8.31 to-3.14,P<0.0001),Decreased St George's Respiratory Questionnaire total score(MD-7.39,95%CI:-10.46 to-4.31,P<0.00001),increased 6-min walk distance in meters(MD 78.46,95%CI:60.18–96.73,P<0.00001),increased forced expiratory volume 1%(MD 6.49,95%CI:3.64–9.33,P<0.00001),increased CD4(MD 9.84,95%CI:6.73–12.94,P<0.00001),CD8(MD-1.84,95%CI:-3.62 to-0.06,P=0.04)and CD4/CD8(MD 0.26,95%CI:0.20–0.32,P<0.0001),and increased immunoglobulin M(MD 0.15,95%CI:0.10–0.20 P<0.00001)..Conclusions:For stable COPD,TKLS combined with CWM is superior to CWM alone with regard to clinical effectiveness,symptoms,and quality of life.The above conclusion needs to be validated by further well-designed,multicentric,large-scale,double-blinded RCTs. 展开更多
关键词 Chronic obstructive pulmonary disease traditional Chinese medicine tonifying kidney LUNG and spleen systematic review META-ANALYSIS randomized controlled trial
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Study of Different Patterns of Immuno-Modulatory Mechanism byTonifying Kidney and Invigorating Spleen Drugs
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作者 沈自尹 蔡定芳 +2 位作者 张玲娟 陈晓红 钟历勇 《Chinese Journal of Integrative Medicine》 SCIE CAS 1998年第4期278-281,共4页
Objective: To observe the acting pattern on the immune system by Kidney tonifying (KT) drugs. Methods: Three composite recipes were used on the 7- and 14-day corticosterone rat model to study the effect of recipes on... Objective: To observe the acting pattern on the immune system by Kidney tonifying (KT) drugs. Methods: Three composite recipes were used on the 7- and 14-day corticosterone rat model to study the effect of recipes on the different patterns of immuno-modulatory and neuro- endocrinological systems. Results:The immune system of Spleen Invigorating(SI) group was well protected in either 7- or 14-day experiments,with the SI recipe showing no effect on the neuroendocrine system. It suggested that SI recipe might have direct action on immune system. On the other hand, KT group with no effect on neuroendocrine-immune (NEI) system in 7-day experiment, but showed a remarkable protective effect of the whole NEI system in 14-day experiment. Conclusion: The results indicated that KT recipe acts on the neuroendocrine system first, and then influence the immune system. It means that the action took place through down pathway of NEI network. 展开更多
关键词 kidney tonifying spleen invigorating corticosterone rat Youguiyin
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从“虚瘀劫肝”论原发性肝癌中医药防治思路 被引量:1
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作者 王明刚 蓝艳梅 +2 位作者 蒋祖玲 蒙健林 刘潇 《现代中医药》 CAS 2024年第2期31-36,共6页
理论创新是中医药发展的源泉,在新理论指导下形成的新方药或新诊治方案是中医药临床防治重大疑难疾病的新突破口。正邪交争,正不胜邪是慢性疾病持续进展的内在驱力和一般特性,慢性肝病持续恶性进展囊括了:肝纤维、肝硬化、肝癌等逐步恶... 理论创新是中医药发展的源泉,在新理论指导下形成的新方药或新诊治方案是中医药临床防治重大疑难疾病的新突破口。正邪交争,正不胜邪是慢性疾病持续进展的内在驱力和一般特性,慢性肝病持续恶性进展囊括了:肝纤维、肝硬化、肝癌等逐步恶化的病理进程。其在遵循中医“正不胜邪”基本病机的基础也必须有其特殊性和指向性,也可理解为在慢性肝病持续进展的病理状态下将一般性的病机进行指向性和特征性的阐发。肝正虚主要是指维持正常肝再生修复的相关机制和途径异常或紊乱,肝邪胜则是指肝损伤因素持续存在及其下游触发的恶性肝再生状态进行性亢进;而“瘀”作为正邪交争过程中产生的最主要病理产物也在不断推动疾病的恶性发展。在此基础上,从“虚瘀劫肝”论肝癌的病理新认识及补虚(补肾生髓、健脾)祛瘀(疏肝、柔肝、化肝)阻断慢性肝病持续恶性进展以防治肝癌的基本思路,期望有益于疑难肝脏病症的临床防治。 展开更多
关键词 原发性肝癌 正邪交争 补肾调肝治脾 虚瘀劫肝 肝再生 理论创新
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基于形气神三位一体生命观论治卵巢早衰性不孕 被引量:1
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作者 揭慧敏 马文君 +1 位作者 熊仪 韩霞 《广州中医药大学学报》 CAS 2024年第8期2189-2195,共7页
形气神三位一体生命观是古人对人体生命的基本认知。卵巢早衰(premature ovarian failure,POF)是卵巢功能丧失的终末阶段,是困扰当代育龄期妇女生活、生育的一大难题。中医认为,人是形、气、神三位一体的有机整体,形、气、神三者中的任... 形气神三位一体生命观是古人对人体生命的基本认知。卵巢早衰(premature ovarian failure,POF)是卵巢功能丧失的终末阶段,是困扰当代育龄期妇女生活、生育的一大难题。中医认为,人是形、气、神三位一体的有机整体,形、气、神三者中的任何一者发生异常都可能直接导致疾病的发生并影响另二者的功能。该文从肾精亏虚及脾失健运导致形体失常、少阳枢机不利而致气机失调、肝气郁结而致神机失守3个方面来认识卵巢早衰性不孕的发病机制,并基于恢复形气神三位一体正常态的治疗思想,采用补肾健脾以补形、运转枢机以理气、疏肝养血以安神之法指导卵巢早衰性不孕的中医治疗。基于“形气神三位一体生命观”论治卵巢早衰性不孕,可深化对卵巢早衰不孕的病因病机认识,充分发挥中医调经种子的优势。 展开更多
关键词 卵巢早衰 不孕 补肾健脾 运转枢机 疏肝养血
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基于数据挖掘的功能性消化不良中医证型分布及用药规律研究
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作者 朱正望 王琳琳 +2 位作者 赵静涵 朱平生 苗明三 《中药新药与临床药理》 CAS CSCD 北大核心 2024年第9期1437-1444,共8页
目的探究功能性消化不良的中医辨证分型及用药规律,为该病的中医治疗提供参考。方法检索中国知网(CNKI)、万方数据库(Wangfang)、维普数据库(VIP)、PubMed、Web of Science数据库中有关中医药治疗功能性消化不良的临床研究文献,收集中... 目的探究功能性消化不良的中医辨证分型及用药规律,为该病的中医治疗提供参考。方法检索中国知网(CNKI)、万方数据库(Wangfang)、维普数据库(VIP)、PubMed、Web of Science数据库中有关中医药治疗功能性消化不良的临床研究文献,收集中药复方,建立数据库,使用Excel 2019、Clementine 12.0和SPSS 21.0对功能性消化不良的中医证型、中药使用频次、功效分类、性味归经进行频次统计,并对高频药物进行关联规则分析、因子分析和聚类分析。结果共纳入文献428篇,提取处方442首,涉及中药225味,高频药物24味,其中党参、茯苓、陈皮、柴胡的使用频次最多,功效分类以补虚药、理气药最为常见,药性以温为主,药味以苦、辛、甘为主,多归脾、肺、胃经;关联规则分析得到20种药物组合,因子分析提取了9个公因子,聚类分析可将药物分为4类。功能性消化不良肝胃不和证最多,对其进行关联规则分析得到12种药物组合,因子分析提取了3个公因子,聚类分析可将药物分为2类。结论中医临床治疗功能性消化不良以益气健脾、疏肝行气药为主,甘温补虚、辛开苦降,辨证配伍化湿、解表、清热等药物。 展开更多
关键词 功能性消化不良 中医证型 肝胃不和证 用药规律 关联规则 因子分析 聚类分析 益气健脾 疏肝行气
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王济华治疗风湿病经验 被引量:1
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作者 孙芳 傅文 +1 位作者 冯福海 王济华 《河南中医》 2024年第7期1055-1060,共6页
王济华教授认为,风湿病的基本病机为人体阴阳失调,正气亏虚,外感风寒湿邪,表邪入里郁而化热,导致痹阻关节、肌肉、筋骨,病情日久多见肝肾不足、气血亏虚、脾虚湿胜、痰瘀交阻等。王教授治疗风湿病常个体化分辨患者风寒湿之偏重、阴阳气... 王济华教授认为,风湿病的基本病机为人体阴阳失调,正气亏虚,外感风寒湿邪,表邪入里郁而化热,导致痹阻关节、肌肉、筋骨,病情日久多见肝肾不足、气血亏虚、脾虚湿胜、痰瘀交阻等。王教授治疗风湿病常个体化分辨患者风寒湿之偏重、阴阳气血之盛衰,遵循轻微解表发汗,兼顾温经止痛,重视健脾化湿、热痹当清、调补气血、虫类药化瘀剔络、滋补肝肾等治痹要点,组方精妙、配伍严谨、疗效肯定,可有效缓解关节炎症,减轻症状,改善患者生活质量。王济华教授强调,对于沉寒痼冷痹阻络脉,一般温药不能奏效,必用附子、乌头之品,用药时需要注重辨证准确、炮制方法得当、用量适度,且需在正确配伍的前提下间断运用,密切观察,以防蓄积中毒,而达到增效减毒的目的。 展开更多
关键词 风湿病 解表发汗 温经止痛 健脾化湿 热痹当清 调补气血 化瘀剔络 滋补肝肾 王济华
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从疏肝补肾健脾论治高泌乳素血症 被引量:1
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作者 车晓璐 曹振健 +1 位作者 杨金禄 朱晓玲 《基层中医药》 2024年第7期6-11,共6页
高泌乳素血症是一种内分泌紊乱性疾病,可影响男女的生殖功能,属中医“乳泣”等范畴。笔者导师曹振健认为,本病应以肝郁、肾虚、脾虚为辨证要点,采用疏肝、补肾、健脾为治疗原则,同时兼顾气滞、血瘀、痰湿等病理因素。其据此拟定清乳汤(... 高泌乳素血症是一种内分泌紊乱性疾病,可影响男女的生殖功能,属中医“乳泣”等范畴。笔者导师曹振健认为,本病应以肝郁、肾虚、脾虚为辨证要点,采用疏肝、补肾、健脾为治疗原则,同时兼顾气滞、血瘀、痰湿等病理因素。其据此拟定清乳汤(柴胡、炒白芍、生麦芽、香附、当归、黄芪、白术、茯苓、续断、桑寄生、菟丝子、女贞子、甘草),并归纳出肝气郁结、肝郁化火、气滞血瘀、肝肾阴虚、脾肾阳虚、肝郁脾虚、脾虚痰湿7种临床常见证型,治疗在主方基础上进行加减,探索中医药治疗高泌乳素血症的临床方法。 展开更多
关键词 高泌乳素血症 中医药疗法 疏肝 补肾 健脾
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国医大师潘敏求治疗脑瘤经验
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作者 曾瀚 唐蔚 潘敏求 《湖南中医药大学学报》 CAS 2024年第11期1937-1941,共5页
颅脑恶性肿瘤是发生在脑神经组织的恶性肿瘤,因其细胞分化不良,生长迅速,难以根治,因而预后不良。国医大师潘敏求教授认为本病发生的病机为肝脾不调、肾气亏虚、风挟痰瘀内阻于脑,病位在脑,与肝脾肾密切相关,病理因素多强调风、痰、瘀... 颅脑恶性肿瘤是发生在脑神经组织的恶性肿瘤,因其细胞分化不良,生长迅速,难以根治,因而预后不良。国医大师潘敏求教授认为本病发生的病机为肝脾不调、肾气亏虚、风挟痰瘀内阻于脑,病位在脑,与肝脾肾密切相关,病理因素多强调风、痰、瘀、毒。治以“疏肝健脾,补肾益精,祛风化痰散瘀”,辨证的重点在于辨虚实,强调根据病情轻重缓急,中西协同,重视情志疏导,根据不同证型及其阶段性变化,有所侧重和兼顾。总结潘敏求教授治疗脑瘤经验,另附验案一则,加以阐明。 展开更多
关键词 脑瘤 肝脾不调 肾气亏虚 风挟痰瘀 疏肝健脾 补肾益精 祛风化痰散瘀
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从发病机制探讨多囊卵巢综合征所致闭经
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作者 张国栋 孙欣 张兰 《实用中医内科杂志》 2024年第1期20-23,共4页
基于肝脾肾三脏,从肝郁气滞,脾虚痰湿,肾虚精亏及冲任二脉剖析多囊卵巢综合征所致闭经病机;此外,从遗传、环境污染、精神压力、胰岛素抵抗等因素简述现代医学发病机制;以肝气郁滞,疏泄不及,横逆己土作为切入点,浅析脾虚及肾,肾虚血瘀的... 基于肝脾肾三脏,从肝郁气滞,脾虚痰湿,肾虚精亏及冲任二脉剖析多囊卵巢综合征所致闭经病机;此外,从遗传、环境污染、精神压力、胰岛素抵抗等因素简述现代医学发病机制;以肝气郁滞,疏泄不及,横逆己土作为切入点,浅析脾虚及肾,肾虚血瘀的发展历程。此外,从五行生克制化方面阐明了肾在该病中的主导地位,从肝郁、脾虚、肾亏的中医理论探讨了多囊卵巢综合征致闭经发病过程和病变特点,确立了疏肝理气、健脾燥湿、补肾填精的主要治法,同时对兼有痰浊内生、瘀血阻络者,提出化痰降浊,通络化瘀的治法。 展开更多
关键词 多囊卵巢综合征 闭经 疏肝理气 健脾燥湿 补肾填精
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罕见外生型肝癌1例
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作者 马翠翠 施卫兵 郭锦晨 《中医药临床杂志》 2024年第11期2219-2222,共4页
外生型肝癌是一种特殊类型的肝细胞癌,属罕见病,易发生肿瘤破裂出血等致死性并发症,西医以手术、介入治疗为主。报告运用中西医结合治疗不能手术、介入治疗的外生型肝癌1例,该患者以血性腹水、甲胎蛋白升高为主要特征,西医以保肝利尿、... 外生型肝癌是一种特殊类型的肝细胞癌,属罕见病,易发生肿瘤破裂出血等致死性并发症,西医以手术、介入治疗为主。报告运用中西医结合治疗不能手术、介入治疗的外生型肝癌1例,该患者以血性腹水、甲胎蛋白升高为主要特征,西医以保肝利尿、支持对症治疗为主,中医治以益气健脾、化瘀止血、软坚散结为大法,配合中医外治。经治患者腹水消退、肿瘤指标下降,病情稳定。 展开更多
关键词 外生型肝癌 血性腹水 益气健脾 化瘀止血 软坚散结
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中医药防治化疗后骨髓抑制研究进展 被引量:1
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作者 秦沛怡 宋永蕾 谭兆峰 《河南中医》 2024年第8期1290-1296,共7页
中医药防治化疗后骨髓抑制的常用治法有补肾生髓法、健脾养血法、解毒活血法、益气养阴法、疏肝调肝法等,疗效确切,不良反应少,可改善患者生活质量。目前,研究仍存在以下不足:临床研究中符合循证医学原则的多中心随机双盲对照研究较少,... 中医药防治化疗后骨髓抑制的常用治法有补肾生髓法、健脾养血法、解毒活血法、益气养阴法、疏肝调肝法等,疗效确切,不良反应少,可改善患者生活质量。目前,研究仍存在以下不足:临床研究中符合循证医学原则的多中心随机双盲对照研究较少,中医辨证分型尚缺乏统一的标准和客观依据与规范;中医药防治化疗后骨髓抑制与西医治疗的结合应用还不够充分;关于中医药抗化疗后骨髓抑制在细胞、分子微观水平方面的研究有一定进展,但由于中药方剂成分复杂,明确具体机制存在较大困难,联合用药的协同效应以及治疗效果的科学证据还相对不足。今后,需进一步探索和研究中医药防治化疗后骨髓抑制的临床应用前景,提高临床研究质量,深入研究中医药抗化疗后骨髓抑制的作用机理。 展开更多
关键词 骨髓抑制 化疗 恶性肿瘤 补肾生髓法 健脾养血法 解毒活血法 益气养阴法 疏肝调肝法
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平木法临证经验刍议
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作者 李永红 王丹 +6 位作者 杨文婷 陈响 于鑫 王惠敏 邱丽蓉 邹金芯 张俞 《中国中医药现代远程教育》 2024年第13期55-58,共4页
中医学理论认为,肝的主要生理功能是主疏泄、主藏血。肝疏泄功能的失调造成气机紊乱,可引发全身多种病证,临床常见的有肝旺侮肺、木旺乘土、水不涵木等。肝属中焦,其气机的紊乱会导致多个相关脏腑功能紊乱。运用“调中化湿”理论,通过... 中医学理论认为,肝的主要生理功能是主疏泄、主藏血。肝疏泄功能的失调造成气机紊乱,可引发全身多种病证,临床常见的有肝旺侮肺、木旺乘土、水不涵木等。肝属中焦,其气机的紊乱会导致多个相关脏腑功能紊乱。运用“调中化湿”理论,通过佐金平木、扶土抑木、滋水涵木等方法调理中焦,可治疗肝失疏泄所致的病证。 展开更多
关键词 佐金平木 扶土抑木 滋水涵木
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中医运用小儿退敏汤治疗儿童过敏性结膜炎经验
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作者 潘婷婷 王方 《中医眼耳鼻喉杂志》 2024年第3期167-169,共3页
王方教授总结儿童过敏性结膜炎的病因主要是先天不足、后天失养、外感邪气、饮食内伤,情志失调,其病机关键在于脾气不足、肝经风热;治疗主张从肝脾论治,临证确立以清肝补脾为基本治疗大法,兼以祛风止痒,方用小儿退敏汤随症加减,临床疗... 王方教授总结儿童过敏性结膜炎的病因主要是先天不足、后天失养、外感邪气、饮食内伤,情志失调,其病机关键在于脾气不足、肝经风热;治疗主张从肝脾论治,临证确立以清肝补脾为基本治疗大法,兼以祛风止痒,方用小儿退敏汤随症加减,临床疗效颇佳。 展开更多
关键词 儿童过敏性结膜炎 清肝补脾 中医药疗法
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健脾疏肝推拿六法结合加味二陈汤治疗小儿脾虚夹积型积滞的临床效果分析
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作者 张斌 《智慧健康》 2024年第15期56-59,63,共5页
目的探究健脾疏肝推拿六法与加味二陈汤联合治疗小儿脾虚夹积型积滞的治疗效果。方法选取2022年5月—2023年5月本院收治的60例小儿脾虚夹积型积滞患者为研究对象,以随机数字表法将患者分为参照组与联合组,每组30例。其中,参照组采用健... 目的探究健脾疏肝推拿六法与加味二陈汤联合治疗小儿脾虚夹积型积滞的治疗效果。方法选取2022年5月—2023年5月本院收治的60例小儿脾虚夹积型积滞患者为研究对象,以随机数字表法将患者分为参照组与联合组,每组30例。其中,参照组采用健脾疏肝推拿六法,联合组采用健脾疏肝推拿六法与加味二陈汤结合治疗。观察两组患者的疗效、中医症状积分、生活质量与胃肠激素水平。结果联合组的总有效率比参照组高(P<0.05)。干预后联合组的中医症状积分比参照组低,生活质量得分比参照组高(P<0.05)。干预后联合组GAS和MOT低于参照组,SS高于参照组(P<0.05)。结论在小儿脾虚夹积型积滞治疗过程中,采用健脾疏肝推拿六法结合加味二陈汤的治疗方案,能有效提高患儿的中医证候积分,同时调节胃肠道激素水平,从而显著提升患儿的生活质量。这一治疗方案体现了中医治疗的优势,对患儿的康复具有积极意义。 展开更多
关键词 健脾疏肝推拿六法 加味二陈汤 小儿脾虚夹积型积滞 临床症状
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调肝、补肾、健脾方药对慢性心理应激大鼠单胺类神经递质影响的比较研究 被引量:29
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作者 严灿 徐志伟 +4 位作者 李艳 史亚飞 邓中炎 潘毅 谭炳炎 《中国中西医结合杂志》 CAS CSCD 北大核心 2002年第12期925-928,共4页
目的:观察慢性心理应激反应大鼠血浆和下丘脑多巴胺(DA)、5-羟色胺(5-HT)、肾上腺素(E)、去甲肾上腺素(NE)的变化及调肝、补肾、健脾方药对其影响。方法:Wistar大鼠按体重随机分为6组,即对照组(C),模型组(M),调肝中药(加味四逆散)组(C1)... 目的:观察慢性心理应激反应大鼠血浆和下丘脑多巴胺(DA)、5-羟色胺(5-HT)、肾上腺素(E)、去甲肾上腺素(NE)的变化及调肝、补肾、健脾方药对其影响。方法:Wistar大鼠按体重随机分为6组,即对照组(C),模型组(M),调肝中药(加味四逆散)组(C1),人参总皂甙组(C2),补肾中药(肾气丸)组(C3),健脾中药(四君子汤)组(C4)。采用束缚限制活动空间的方法造成慢性心理应激大鼠模型,所有药物灌胃给药。采用电化学高效液相色谱分析方法检测血浆和下丘脑DA、5-HT、E、NE含量。结果:应激大鼠血浆和下丘脑DA、5-HT含量明显降低(均P<0.01),血浆NE、E含量明显升高(均P<0.01),而下丘脑NE含量无明显变化。血浆5-HT/NE、5-HT/E及下丘脑5-HT/NE均明显降低(均P<0.01)。加味四逆散可以升高应激大鼠下丘脑和血浆中DA、5-HT含量(均P<0.01),并能降低血浆中NE、E含量(均P<0.01),升高下丘脑和血浆5-HT/NE以及血浆5-HT/E(P<0.05或P<0.01)。肾气丸、四君子汤及人参总皂甙虽然对有些指标有影响,但对心理应激的整体调节作用不如加味四逆散。结论:加味四逆散对慢性心理应激大鼠血浆和下丘脑单胺类神经递质的代谢紊乱均有良好的调节作用,调肝、补肾、健脾治法方药中以调肝治法方药的综合调治作用最为显著。 展开更多
关键词 心理应激 单胺类神经递质 高效液相色谱分析 调肝 补肾 健脾 中药 药理
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