Objective: To explore the mechanism of treating endometriosis by tonifying Kidney and removing blood stasis with Neiyixiao recipe, ( , NYXR).Methods: One hundred and three patients of endometriosis were divided rando...Objective: To explore the mechanism of treating endometriosis by tonifying Kidney and removing blood stasis with Neiyixiao recipe, ( , NYXR).Methods: One hundred and three patients of endometriosis were divided randomly into the NYXR group (58 cases, treated with NYXR) and the control group (45 cases, treaed with danazol) and were reviewed for the improvement of clinical symptoms, serum level of FSH, LH, PRL, E2, P and T, humoral and cellular immunity (C3, C4, CD3, CD4, CD8), and plasma prostaglandin after treatment.Results: There was no significant difference in effect between the NYXR group and the control group in relief of dysmenorrhea and degradation of elevated plasma prostaglandin (x2 = 0.71,P >0.05). But there was significant difference between the two groups in curing infertility (x2 = 14.77, P<0. 01), and the effect of NYXR in regulating endocrine and immunity was significantly better than that of danazol.Conclusion: By tonifying Kidney and removing blood stasis, NYXR is multi-effective and being one of effective methods in clinical practice for treatment of endometriosis.展开更多
目的:整体评价清利化瘀类复方保留灌肠治疗慢性前列腺炎的临床疗效以及安全性,为临床应用提供客观依据及用药参考。方法:检索中文文献数据库中国生物医学文献数据库、中国知网、万方数据库、重庆维普中文科技期刊数据库,英文数据库Medl...目的:整体评价清利化瘀类复方保留灌肠治疗慢性前列腺炎的临床疗效以及安全性,为临床应用提供客观依据及用药参考。方法:检索中文文献数据库中国生物医学文献数据库、中国知网、万方数据库、重庆维普中文科技期刊数据库,英文数据库Medline、Embase、Cochrane Library、Web of Science与PubMed(时间至2022年2月),收集关于清利化瘀类复方保留灌肠单用或联合其他疗法治疗慢性前列腺炎的随机对照试验,采用RevMan 5.4软件对最终纳入的25篇文献研究进行Meta分析。结果:25项研究的总样本量为2879例。Meta分析结果显示:清利化瘀类复方灌肠治疗慢性前列腺炎的有效率[OR=4.61,95%CI(3.64,5.84)]、美国国立卫生研究院慢性前列腺炎症状指数(National Institutes of Health Chronic Prostatitis Index,NIH-CPSI)[MD=-6.02,95%CI为(-6.27,-5.78)]均优于非清利化瘀类中药灌肠治疗的对照组。结论:清利化瘀法复方灌肠参与干预的试验组比对照组总有效率高、NIP-CPSI评分降低更明显,且安全性好。展开更多
目的探讨温补脾肾、化瘀利水法治疗脾肾阳虚夹湿瘀型糖尿病肾病水肿的疗效和机制。方法本研究采用随机对照研究,选择长春中医药大学附属医院门诊和住院脾肾阳虚夹湿瘀型糖尿病肾病水肿患者进行随机分组。对照组给予降糖、降压、降脂等...目的探讨温补脾肾、化瘀利水法治疗脾肾阳虚夹湿瘀型糖尿病肾病水肿的疗效和机制。方法本研究采用随机对照研究,选择长春中医药大学附属医院门诊和住院脾肾阳虚夹湿瘀型糖尿病肾病水肿患者进行随机分组。对照组给予降糖、降压、降脂等对症治疗;治疗组在对照组治疗基础上,给予温补脾肾、化瘀利水法治疗,口服中药汤剂,以金匮肾气丸、大黄虫丸为基础方加减。结果数据经统计分析显示,治疗后治疗组24 h UTP、Cr、BUN明显下降,与治疗前相比,差异有统计学意义(P<0.05),且ALB、尿量均较前明显增加,差异有统计学意义(P<0.05);对照组治疗后24 h UTP、Cr、BUN有所下降,与治疗前相比,差异有统计学意义(P<0.05),但ALB、尿量均较前减少,组间比较,治疗组明显优于对照组(P<0.05)。治疗组的总有效率96.67%(29/30)高于对照组66.67%(20/30),差异有统计学意义(P<0.05)。结论温补脾肾、化瘀利水法能减轻脾肾阳虚夹湿瘀型糖尿病肾病水肿,延缓进入血液透析的时间。展开更多
文摘Objective: To explore the mechanism of treating endometriosis by tonifying Kidney and removing blood stasis with Neiyixiao recipe, ( , NYXR).Methods: One hundred and three patients of endometriosis were divided randomly into the NYXR group (58 cases, treated with NYXR) and the control group (45 cases, treaed with danazol) and were reviewed for the improvement of clinical symptoms, serum level of FSH, LH, PRL, E2, P and T, humoral and cellular immunity (C3, C4, CD3, CD4, CD8), and plasma prostaglandin after treatment.Results: There was no significant difference in effect between the NYXR group and the control group in relief of dysmenorrhea and degradation of elevated plasma prostaglandin (x2 = 0.71,P >0.05). But there was significant difference between the two groups in curing infertility (x2 = 14.77, P<0. 01), and the effect of NYXR in regulating endocrine and immunity was significantly better than that of danazol.Conclusion: By tonifying Kidney and removing blood stasis, NYXR is multi-effective and being one of effective methods in clinical practice for treatment of endometriosis.
文摘目的:整体评价清利化瘀类复方保留灌肠治疗慢性前列腺炎的临床疗效以及安全性,为临床应用提供客观依据及用药参考。方法:检索中文文献数据库中国生物医学文献数据库、中国知网、万方数据库、重庆维普中文科技期刊数据库,英文数据库Medline、Embase、Cochrane Library、Web of Science与PubMed(时间至2022年2月),收集关于清利化瘀类复方保留灌肠单用或联合其他疗法治疗慢性前列腺炎的随机对照试验,采用RevMan 5.4软件对最终纳入的25篇文献研究进行Meta分析。结果:25项研究的总样本量为2879例。Meta分析结果显示:清利化瘀类复方灌肠治疗慢性前列腺炎的有效率[OR=4.61,95%CI(3.64,5.84)]、美国国立卫生研究院慢性前列腺炎症状指数(National Institutes of Health Chronic Prostatitis Index,NIH-CPSI)[MD=-6.02,95%CI为(-6.27,-5.78)]均优于非清利化瘀类中药灌肠治疗的对照组。结论:清利化瘀法复方灌肠参与干预的试验组比对照组总有效率高、NIP-CPSI评分降低更明显,且安全性好。
文摘目的探讨温补脾肾、化瘀利水法治疗脾肾阳虚夹湿瘀型糖尿病肾病水肿的疗效和机制。方法本研究采用随机对照研究,选择长春中医药大学附属医院门诊和住院脾肾阳虚夹湿瘀型糖尿病肾病水肿患者进行随机分组。对照组给予降糖、降压、降脂等对症治疗;治疗组在对照组治疗基础上,给予温补脾肾、化瘀利水法治疗,口服中药汤剂,以金匮肾气丸、大黄虫丸为基础方加减。结果数据经统计分析显示,治疗后治疗组24 h UTP、Cr、BUN明显下降,与治疗前相比,差异有统计学意义(P<0.05),且ALB、尿量均较前明显增加,差异有统计学意义(P<0.05);对照组治疗后24 h UTP、Cr、BUN有所下降,与治疗前相比,差异有统计学意义(P<0.05),但ALB、尿量均较前减少,组间比较,治疗组明显优于对照组(P<0.05)。治疗组的总有效率96.67%(29/30)高于对照组66.67%(20/30),差异有统计学意义(P<0.05)。结论温补脾肾、化瘀利水法能减轻脾肾阳虚夹湿瘀型糖尿病肾病水肿,延缓进入血液透析的时间。