In order to explore the difference of intraocular pressure（IOP） at different points of cornea before and after laser in situ keratomileusis（LASIK）,IOP was measured by Tono-Pen Tonometer at central cornea,pericentr...In order to explore the difference of intraocular pressure（IOP） at different points of cornea before and after laser in situ keratomileusis（LASIK）,IOP was measured by Tono-Pen Tonometer at central cornea,pericentral cornea and limbus respectively and analyzed statistically.After LASIK,IOP was dropped significantly at central cornea and pericentral cornea（P〈0.05）,while no statistically significant change occurred at limbus（P〉0.05）.There was no statistically significant difference in IOP at different points before LASIK（F=0.110,P=0.896）,but statistically significant difference was found after LASIK（F=7.375,P=0.001）.It was suggested that reliable IOP after LASIK could be obtained from the limbus by Tono-Pen tonometer.展开更多
AIM: Tono-pen measurement of intraocular pressure(IOP) under topical anaesthesia in full term normal newborns. ·METHODS: The IOP measurements were taken using Tono-pen XL tonometer under topical anaesthesia in 15...AIM: Tono-pen measurement of intraocular pressure(IOP) under topical anaesthesia in full term normal newborns. ·METHODS: The IOP measurements were taken using Tono-pen XL tonometer under topical anaesthesia in 150 newborns(300 eyes) within 24h after birth,over a period of three months,in a university hospital. Gender,gestation period,mode of delivery and birth weight of newborns were noted from medical records. ·RESULTS: There were 70 males and 80 females. All babies were Malays. The IOP measurements were taken between 12 and 24h after birth. The gestation period of babies ranged between 37 and 41 weeks; 118 babies were delivered by spontaneous vaginal delivery and 32 by caesarian section. The birth weight of babies ranged between 2.1 and 4.3kg. The mean IOP of 300 eyes was 15.99±2.79mmHg(range 8-22). There was no statistically significant difference of mean IOP and gender,laterality of eye,type of delivery,gestation age,or birth weight of newborns. ·CONCLUSION: The IOP in full term normal newborns was 16mmHg. Tono-Pen appears to be ideal instrument for taking IOP in newborns because of its small size and easy handling.展开更多
Purpose: The accuracy of Goldmann applanation tonometry (GAT) has been shown to depend on several biomechanical properties of the cornea. Newer tonometry devices (e.g., the Dynamic Contour Tonometer PASCAL? [DCT] and ...Purpose: The accuracy of Goldmann applanation tonometry (GAT) has been shown to depend on several biomechanical properties of the cornea. Newer tonometry devices (e.g., the Dynamic Contour Tonometer PASCAL? [DCT] and the Tono-Pen? XL [TP]) have been designed to accurately measure intraocular pressure (IOP) independent of corneal thickness (CCT) and pathology. This study investigates the influence of corneal pathologies on the accuracy of these IOP measuring devices, and compares this accuracy to that of direct intracameral IOP measurement. Methods: 8 eyes of 8 patients suffering from corneal pathologies scheduled for penetrating keratoplasty, and 10 eyes of 10 patients scheduled for cataract surgery (control group) were examined. Before surgery, the anterior chamber was cannulated at the temporal corneal limbus. In a closed system, the intraocular pressure (IOP) was directly set to 10, 20, and 30 mmHg with a manometric water column. Intraocular pressure measurements taken by GAT, DCT, and TP were compared to intracameral measurements obtained by a precision reference pressure sensor. Results: Control group: All three methods showed good agreement with the intracameral readings (mean deviation of all three devices, -0.9 mmHg). Group with corneal pathologies: The TP yielded the most exact IOP values in the group with corneal pathologies when taking all diagnoses into account. The mean deviations from the intracameral IOP measurements were -0.9 mmHg ± 3.2 mmHg (mean ± SD) for TP, -2.9 mmHg ± 3.3 mmHg for GAT, and -5.0 mmHg ± 7.9 mmHg for DCT. For bullous keratopathy, the most exact IOP readings were obtained by the TP (mean deviation -0.2 mmHg ± 3.5 mmHg). The TP and GAT devices underestimated IOP in the patients with Fuchs’ endothelial dystrophy;all 3 devices underestimated adjusted IOP after keratoplasty. DCT showed the greatest deviations from adjusted IOP in the case of non-herpetic scars. In the control group, none of the devices showed a statistically relevant dependency on CCT. Nevertheless, in the group with corneal pathologies, only TP showed no dependency on CCT. Conclusion: Our results suggest that the Tono-Pen XL? is the most accurate measurement device to determine IOP in patients with corneal pathologies, especially in patients suffering from corneal edema (bullous keratopathy). GAT yielded surprisingly exact IOP values in patients suffering from irregular corneal surface. DCT showed a high degree of deviation from the adjusted IOP, and should not be used to determine IOP in corneas with the disorders listed here.展开更多
AIM：To analyze the correlation of Goldmann applanation tonometer（GAT）,I-Care tonometer and Tono-Pen tonometer results in young healthy persons,and to investigate the influence of central corneal thickness（CCT）on ...AIM：To analyze the correlation of Goldmann applanation tonometer（GAT）,I-Care tonometer and Tono-Pen tonometer results in young healthy persons,and to investigate the influence of central corneal thickness（CCT）on intraocular pressure（IOP）measurements recorded with these tonometers.·M ETHODS：We conducted a pilot clinical study in 78eyes of 78 subjects aged 22-28 years old（44 women and34 men;mean age 23.8±1.19y）.IOP was measured using GAT,I-Care and Tono-Pen tonometers,followed by measurements of CCT.Statistical analysis was performed using SPSS 20.0.·RESULTS：The mean IOPs and standard deviation（±SD）for GAT,I-Care and Tono-Pen were 15.62±2.281 mm Hg,16.29±2.726 mm Hg and 16.32±2.393 mm Hg,respectively.The mean CCT was 555.15±29.648μm.Clear positive correlations between GAT and I-Care,GAT and TonoPen,and I-Care and Tono-Pen tonometers were found（=0.867,〈0.001;=0.861,〈0.001;=0.915,〈0.001,respectively）.In comparison between devices,BlandAltman analysis showed a significant mean difference（MD）in the measurements by GAT and I-Care of-0.679 mm Hg and by GAT and Tono-Pen of-0.705 mm Hg（〈0.001）,but there was no significant difference between I-Care and Tono-Pe（〉0.05）.Both non-gold standard tonometers were affected by CCT;that is,both I-Care and Tono-Pen tonometer values were significantly higher with higher CCT means（〉555μm;MD=-1.282,〈0.001;MD=-0.949,〈0.001,respectively）compared with GAT.·CONCLUSION：Both I-Care and Tono-Pen tonometers overestimated IOP compared with the GAT values.Either the I-Care or Tono-Pen tonometer could be used instead of GAT because there was no significant difference between their results.Higher CCT values（〉555μm）were associated with overestimated IOP values.展开更多
基金supported by the grants from the Science Foundation of Hubei Province,China (No. 2008CDB214,No. 2010CDB09802)
文摘In order to explore the difference of intraocular pressure（IOP） at different points of cornea before and after laser in situ keratomileusis（LASIK）,IOP was measured by Tono-Pen Tonometer at central cornea,pericentral cornea and limbus respectively and analyzed statistically.After LASIK,IOP was dropped significantly at central cornea and pericentral cornea（P〈0.05）,while no statistically significant change occurred at limbus（P〉0.05）.There was no statistically significant difference in IOP at different points before LASIK（F=0.110,P=0.896）,but statistically significant difference was found after LASIK（F=7.375,P=0.001）.It was suggested that reliable IOP after LASIK could be obtained from the limbus by Tono-Pen tonometer.
文摘AIM: Tono-pen measurement of intraocular pressure(IOP) under topical anaesthesia in full term normal newborns. ·METHODS: The IOP measurements were taken using Tono-pen XL tonometer under topical anaesthesia in 150 newborns(300 eyes) within 24h after birth,over a period of three months,in a university hospital. Gender,gestation period,mode of delivery and birth weight of newborns were noted from medical records. ·RESULTS: There were 70 males and 80 females. All babies were Malays. The IOP measurements were taken between 12 and 24h after birth. The gestation period of babies ranged between 37 and 41 weeks; 118 babies were delivered by spontaneous vaginal delivery and 32 by caesarian section. The birth weight of babies ranged between 2.1 and 4.3kg. The mean IOP of 300 eyes was 15.99±2.79mmHg(range 8-22). There was no statistically significant difference of mean IOP and gender,laterality of eye,type of delivery,gestation age,or birth weight of newborns. ·CONCLUSION: The IOP in full term normal newborns was 16mmHg. Tono-Pen appears to be ideal instrument for taking IOP in newborns because of its small size and easy handling.
文摘Purpose: The accuracy of Goldmann applanation tonometry (GAT) has been shown to depend on several biomechanical properties of the cornea. Newer tonometry devices (e.g., the Dynamic Contour Tonometer PASCAL? [DCT] and the Tono-Pen? XL [TP]) have been designed to accurately measure intraocular pressure (IOP) independent of corneal thickness (CCT) and pathology. This study investigates the influence of corneal pathologies on the accuracy of these IOP measuring devices, and compares this accuracy to that of direct intracameral IOP measurement. Methods: 8 eyes of 8 patients suffering from corneal pathologies scheduled for penetrating keratoplasty, and 10 eyes of 10 patients scheduled for cataract surgery (control group) were examined. Before surgery, the anterior chamber was cannulated at the temporal corneal limbus. In a closed system, the intraocular pressure (IOP) was directly set to 10, 20, and 30 mmHg with a manometric water column. Intraocular pressure measurements taken by GAT, DCT, and TP were compared to intracameral measurements obtained by a precision reference pressure sensor. Results: Control group: All three methods showed good agreement with the intracameral readings (mean deviation of all three devices, -0.9 mmHg). Group with corneal pathologies: The TP yielded the most exact IOP values in the group with corneal pathologies when taking all diagnoses into account. The mean deviations from the intracameral IOP measurements were -0.9 mmHg ± 3.2 mmHg (mean ± SD) for TP, -2.9 mmHg ± 3.3 mmHg for GAT, and -5.0 mmHg ± 7.9 mmHg for DCT. For bullous keratopathy, the most exact IOP readings were obtained by the TP (mean deviation -0.2 mmHg ± 3.5 mmHg). The TP and GAT devices underestimated IOP in the patients with Fuchs’ endothelial dystrophy;all 3 devices underestimated adjusted IOP after keratoplasty. DCT showed the greatest deviations from adjusted IOP in the case of non-herpetic scars. In the control group, none of the devices showed a statistically relevant dependency on CCT. Nevertheless, in the group with corneal pathologies, only TP showed no dependency on CCT. Conclusion: Our results suggest that the Tono-Pen XL? is the most accurate measurement device to determine IOP in patients with corneal pathologies, especially in patients suffering from corneal edema (bullous keratopathy). GAT yielded surprisingly exact IOP values in patients suffering from irregular corneal surface. DCT showed a high degree of deviation from the adjusted IOP, and should not be used to determine IOP in corneas with the disorders listed here.
文摘AIM：To analyze the correlation of Goldmann applanation tonometer（GAT）,I-Care tonometer and Tono-Pen tonometer results in young healthy persons,and to investigate the influence of central corneal thickness（CCT）on intraocular pressure（IOP）measurements recorded with these tonometers.·M ETHODS：We conducted a pilot clinical study in 78eyes of 78 subjects aged 22-28 years old（44 women and34 men;mean age 23.8±1.19y）.IOP was measured using GAT,I-Care and Tono-Pen tonometers,followed by measurements of CCT.Statistical analysis was performed using SPSS 20.0.·RESULTS：The mean IOPs and standard deviation（±SD）for GAT,I-Care and Tono-Pen were 15.62±2.281 mm Hg,16.29±2.726 mm Hg and 16.32±2.393 mm Hg,respectively.The mean CCT was 555.15±29.648μm.Clear positive correlations between GAT and I-Care,GAT and TonoPen,and I-Care and Tono-Pen tonometers were found（=0.867,〈0.001;=0.861,〈0.001;=0.915,〈0.001,respectively）.In comparison between devices,BlandAltman analysis showed a significant mean difference（MD）in the measurements by GAT and I-Care of-0.679 mm Hg and by GAT and Tono-Pen of-0.705 mm Hg（〈0.001）,but there was no significant difference between I-Care and Tono-Pe（〉0.05）.Both non-gold standard tonometers were affected by CCT;that is,both I-Care and Tono-Pen tonometer values were significantly higher with higher CCT means（〉555μm;MD=-1.282,〈0.001;MD=-0.949,〈0.001,respectively）compared with GAT.·CONCLUSION：Both I-Care and Tono-Pen tonometers overestimated IOP compared with the GAT values.Either the I-Care or Tono-Pen tonometer could be used instead of GAT because there was no significant difference between their results.Higher CCT values（〉555μm）were associated with overestimated IOP values.
