Comprehensive effects of traditional Chinese medicine treatment on heart failure and changes in B-type natriuretic peptide levels: A meta-analysis

BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,systematic evalua-tions of its impact on clinical outcomes,TCM syndrome scores,and B-type natriuretic peptide(BNP)levels are lacking.This study fills this gap through a comprehensive analysis of randomized controlled trials(RCTs)focusing on TCM for HF treatment.It encompasses an assessment of methodological quality,a meta-analysis,and an evaluation of evidence quality based on established standards.The results offer crucial insights into the potential advantages and constraints of TCM in HF management.RCTs on TCM for HF treatment published since the establishment of the database were searched in four Chinese and English databases,including China National Knowledge Infrastructure,Wanfang,VIP Information Chinese Science and Technology Journal,and PubMed.Methodological quality was assessed for the included studies with the Cochrane risk-of-bias assessment tool,and the meta-analysis and publication bias assessment was performed with the RevMan5.3 software.Finally,the quality of evidence was rated according to the GRADE criteria.RESULTS A total of 1098 RCTs were initially retrieved.After screening,16 RCTs were finally included in our study,which were published between 2020 and 2023.These RCTs involved 1660 HF patients,including 832 in the TCM group[TCM combined with conventional Western medicine(CMW)treatment]and 828 in the CWM group(CWM treatment).The course of treatments varied from 1 wk to 3 months.TCM syndrome differentiation was analyzed in 11 of the included RCTs.In all included RCTs,outcome indicators included comprehensive clinical outcomes,TCM syndrome scores,and BNP levels.The meta-analysis results showed significant differences between the TCM and CWM groups in terms of comprehensive clinical outcomes[risk ratio=-0.54;95%confidence interval(CI)=-0.61,-0.47;P<0.00001],TCM syndrome scores[weighted mean difference(WMD)=-142.07;95%CI=-147.56,-136.57;P<0.00001],and BNP levels(WMD=-142.07;95%CI=-147.56,-136.57;P<0.00001).According to the GRADE criteria,RCTs where"TCM improves clinical comprehensive outcomes"were rated as low-quality evidence,and RCTs where"TCM reduces TCM syndrome scores"or"TCM decreases BNP levels"were rated as medium-quality evidence.CONCLUSION TCM combined with CWM treatment effectively improves comprehensive clinical outcomes and diminishes TCM syndrome scores and BNP levels in HF patients.Given the low and medium quality of the included RCTs,the application of these results should be cautious.

Comprehensive Rehabilitation Therapy of Traditional Chinese Medicine Combined with Modern Rehabilitation Training Improves the Spasticity and Motor Function of Hemiplegia after Stroke

Objective:To analyze the impact of comprehensive rehabilitation therapy of traditional Chinese medicine(TCM)(based on modern rehabilitation training)on the spasticity and motor function in stroke patients with hemiplegia.Methods:Seventy-nine stroke and hemiplegia patients admitted to the hospital from June 2021 to June 2023 were selected and randomly divided into a control group(39 cases)using modern rehabilitation training,and an observation group combined with comprehensive TCM rehabilitation therapy(40 cases),over 1 month.The clinical index data of the two groups were compared.Results:There were differences in the clinical index data between the two groups.The total effective rate after 2 treatment in the observation group(92.50%)was higher than that of the control group(74.36%)(χ^(2)=4.727,P<0.05).All central sensitization inventory(CSI)and stroke quality of life(PRO)scores in both groups were lower after treatment,with the observation group having lower scores as compared to the control group(P<0.05).The scores of FMA(upper limbs,lower limbs),Barthel index scores,and Functional Ambulation Categories(FAC)scores of both groups increased after treatment,with the observation group having higher scores as compared to the control group(P<0.05).Conclusion:Comprehensive TCM rehabilitation therapy had a significant therapeutic effect on patients with hemiplegia after stroke.It improved the patient’s spasticity,limb movement,and walking function.Their daily living abilities and quality of life were also enhanced.

Application and Practice of Traditional Chinese Medicine Characteristic Technology Inheritance in Research and Development of Traditional Chinese Medicine Preparations in Medical Institutions

Medical institution preparations play an important role in the development of hospitals,being one of the main forms of traditional Chinese medicine clinical characteristic medication,as well as an important carrier for the inheritance and innovation of traditional Chinese medicine.In recent years,the research and development of traditional Chinese medicine preparations has become a hot spot in the research and development of preparations by medical institutions.Traditional Chinese medicine preparations prepared by traditional processes and their entrusted preparation matters have changed from the current licensing management to filing management.The registration model of traditional Chinese medicine preparations has undergone significant changes,emphasizing more on real data and evaluation results from the objective world,respecting traditional medication experience,and emphasizing the inheritance and innovative development of traditional technological experience.In the process of following teachers in the inheritance project of traditional Chinese medicine,we combined the inheritance of traditional Chinese medicine characteristic technology with the research and development practice of traditional Chinese medicine preparations in medical institutions,and focused on the analysis and discussion of technical problems such as prescription screening,dosage form selection,process route design and clinical observation of traditional Chinese medicine preparations,hoping to provide reference for scholars in the same field of traditional Chinese medicine.

Research on Technology Development of Traditional Chinese Medicine Extraction Based on Patent Information

Objective To understand the development status of traditional Chinese medicine extraction technology,so as to provide a reference for enterprises and scientific research institutions to determine the direction of technological innovation.Besides,the government can formulate scientific and technological innovation strategies.Methods Based on patent information,statistical methods were applied to analyze the development of traditional Chinese medicine extraction technology.Then,the core technology was identified by constructing a patent citation network.Finally,the main path analysis method was applied to discover the technological evolution path.Results and Conclusion The extraction technology of traditional Chinese medicine is still in the growth stage.At present,its R&D is based on enterprises,supplemented by scientific research institutions.The core technologies are ultrasonic extraction and enzymatic extraction.The main path represented by enzymatic extraction technology reveals the evolution process of traditional Chinese medicine extraction technology.Based on this,relevant suggestions are put forward.Firstly,technological innovation cooperation should be strengthened to explore new models of achievement transformation and cooperation.Secondly,key enterprises of technology clusters should be cultivated to accelerate breakthroughs in core technologies.Thirdly,combined technologies can achieve high-efficiency enzyme-assisted extraction and open up new ways of extracting traditional Chinese medicine.Fourthly,traditional techniques should be improved to develop innovative modern techniques.

Machine learning models for stroke detection by observing the eye-movement features under five-color visual stimuli in traditional Chinese medicine

Objective:To develop a novel diagnostic modality to identify and diagnose stroke in daily life scenarios for improving the therapeutic effects and prognoses of patients.Methods:In this study,16 stroke patients and 24 age-matched healthy participants as controls were recruited for comparative analysis.Leveraging a portable eye-tracking device and integrating traditional Chinese medicine theory with modern color psychology principles,we recorded the eye movement signals and calculated eye movement features.Meanwhile,the stroke recognition models based on eye movement features were further trained by using random forest(RF),k-nearest neighbors(KNN),decision tree(DT),gradient boosting classifier(GBC),XGBoost,and CatBoost.Results:The stroke group and the healthy group showed significant differences in some eye movement features(P<.05).The models trained based on eye movement characteristics had good performances in recognizing stroke individuals,with accuracies ranging from 77.40%to 88.45%.Under the red stimulus,the eye movement model trained by RF became the best machine learning model with a recall of 84.65%,a precision of 86.48%,a F1 score of 85.47%.Among the six algorithms,RF and CatBoost performed better in classification.Conclusion:This study pioneers the application of traditional Chinese medicine's five-color stimuli to visual observation tasks.On the basis of the combined design,the eye-movement models can accurately identify stroke,and the developed high-performance models may be used in daily life scenarios.

Hospital-based health technology assessment:The next frontier for traditional Chinese medicine hospitals

Hospital-based health technology assessment(HB-HTA)is highly valuable in the application of hospital medical technology,cost control,improvement of medical quality,and protection of medical safety,and its use is increasing daily globally.However,in China,HB-HTA is still in its infancy,and it is yet to be adopted in traditional Chinese medicine(TCM).Therefore,this article introduces the application and development of HB-HTA,as well as discusses the current situation of TCM and related future development strategies to provide ideas and references for the development of HB-HTA in TCM.We conclude and recommend that all major stakeholders,including the state,health departments,and hospital leaders,support and promote the exploration and development of HB-HTA in TCM hospitals and integrative medicine hospitals.We also suggest the utilization of existing talents and introduction of other necessary talents to promote better and faster organizational development,as well as suggest the formation of a national and internationally recognized HB-HTA guidance manual and toolkit for TCM hospitals based on both the national HTA guidelines and the evaluation of TCM hospitals pilot projects.Moreover,we recommend that HB-HTA pilot study should be executed with Chinese patent medicine as the starting point to form the implementation process and framework in the TCM arena.

Health technology assessment in traditional Chinese medicine in China: current status, opportunities, and challenges

Objectives:The widespread usage of traditional Chinese medicine(TCM)and the government's emphasis on TCM in China have created a positive macro-environment and great opportunities to develop and strengthen health technology assessment(HTA)in TCM.Over the past ten years,a series of policies have been issued by the government to promote the application of HTA and the development of TCM in China.This study reviews the concepts and characteristics of TCM,summarizes the current status of HTA in TCM,and analyzes the opportunities and challenges faced by HTA development in TCM with respect to deepening of healthcare reforms.Methods:Literature review and website searches were used to acquire information regarding the basic theories of TCM and the current status,opportunities,and challenges for HTA in TCM.Results:The number of articles on HTA in TCM rose substantially,especially those published in China National Knowledge Infrastructure(CNKI).With the optimistic policy environment and huge market demand for TCM,the development of HTA in TCM is expected to flourish in China.However,HTA in TCM also faces numerous challenges such as the absence of a clinical efficacy evaluation system for TCM and insufficient basic research evidence and qualified personnel.Conclusions:TCM has unique characteristic that distinguishes it from Western medicine.Currently,it is important to take all measures to address the existing main challenges and thereby take advantage of the present opportunities to develop and improve HTA in TCM.

Bibliometrics and visual analysis for clinical research on intervention of traditional Chinese medicine nursing technology on rheumatoid arthritis

Objective:The objective of this study is to explore the current situation,clinical research hot spots,and trends of traditional Chinese medicine(TCM)nursing technology in rheumatoid arthritis(RA),to draw a panorama of clinical research,to provide the basis and clues for subsequent high-level evidence integration and further in-depth research.Materials and Methods:Seven databases including China National Knowledge Infrastructure,Chinese Scientific Journal Database(VIP),Wanfang Database,Chinese Biomedical Literature Database(Sino-Med),PubMed,Embase,and the Cochrane Library were searched.The bibliometric method and visualization software CiteSpace were used to conduct a multi-dimensional analysis of the included literature.Results:A total of 805 pieces of literature were included(of them,one was written in German and four in English),and the number of published literature showed an increasing trend year by year.There were only 30(3.73%)pieces of literature published in nursing journals.The hot spots of the co-occurrence map were concentrated in:(1)the nursing of fumigation in RA;(2)the efficacy evaluation of TCM nursing technology on pain,joint malformation,and joint dysfunction caused by RA.The included literature themes focused on five TCM technologies:fumigation,moxibustion,acupoint patching,acupoint injection,and Chinese herbal soaking.The beginning year and strength in TCM fumigation were 2012 and 5.2,and those in moxibustion were 2011 and 3.38.Conclusion:The related studies are on the rise.It has entered the field of international readers with clear research hot spots.However,there are still shortcomings such as little literature published in Chinese nursing core journals,few non-Chinese-related documents,and a lack of international exchanges and cooperation.The current research hot spots in this field are TCM fumigation,and the cutting-edge trend of future research may be fumigation and moxibustion technology.It is suggested that further research can focus on evidence integration and original research on the self-optimization of these two techniques.

Clinical Observation on the Prevention and Treatment of Juvenile Mild Myopia with Traditional Chinese Medicine Comprehensive Therapy

Objective:To observe the clinical effect of traditional Chinese medicine on the prevention and treatment ofjuvenile mild myopia.Methods:One hundred and twenty cases of juvenile mild myopia were randomly divided into six groups,with 20 cases in each group:western medicine group,ultrasonic group,acupuncture group,auricular point group,traditional Chinese oral decoction group,and traditional Chinese medicine comprehensive therapy group.The therapeutic effects of the treatment administered to the six groups were compared.Result:In the post-treatment and follow-up stages,the visual acuity of the traditional Chinese medicine comprehensive therapy group significantly improved along with reduced diopter compared to the other groups(p<0.05).However,the axial length of the six groups had no significant change compared with that before treatment(p>0.05).There were no adverse reactions in any of the patients.Conclusion:In the treatment of juvenile mild myopia,traditional Chinese medicine comprehensive therapy has good therapeutic effect without any adverse reactions;thus,it is worthy of clinical promotion.

Development of chromatographic technologies for the quality control of Traditional Chinese Medicine in the Chinese Pharmacopoeia

As an important branch of medicine, Traditional Chinese Medicine(TCM) has been applied for the treatment of diseases for thousands of years in China and other countries in East Asia. The Chinese Pharmacopoeia(ChP) is a drug code formulated by the Chinese government, and it includes a special volume for the monographs of TCM, which plays an important role in ensuring the quality of drugs. The use of quality control technology has always been a complex and important factor in TCM. Owing to the chemical diversity of TCM, chromatography technology has been proven to be a comprehensive strategy for the assessment of the overall quality of TCM and has become the main analytical method in the ChP.This article provides an overview of the classical and modern chromatographic technologies applied in the ChP, and summarizes the advantages and disadvantages of each technique in the TCM monographs.In 2020, the new edition of the Ch P(the 2020 edition) has been implemented at the end of 2020. This paper also contains a brief introduction about the application of chromatographic technologies in the new edition of the ChP.

Research progress in the treatment of diabetic foot with traditional Chinese medicine

Diabetic foot is one of the chronic complications of diabetes,which is serious and expensive to treat.As an effective method for treating diabetic foot,Chinese medicine plays an important role in improving the clinical symptoms and reducing the suffering of diabetic foot patients.The methods of traditional Chinese medicine to treat diabetic foot include internal treatment method,external treatment method and comprehensive therapy.This article reviews the research results of traditional Chinese medicine treatment of diabetic foot in order to provide reference for the treatment of diabetic foot.

Analysis of the application of Chinese medicine nursing technology in obstetrics

目的:分析中医护理技术在产科的应用价值。方法:以产科的204 例患者为研究,将其随机分为中医组与参照组(n = 102)。参照组患者接受常规护理,中医组患者接受中医护理,比较两组患者的焦虑抑郁评分及患者对护理的满意状态评分。结果:护理前组间评分比较无差别,护理后,中医组在焦虑、抑郁评分改善方面,数值降低幅度显著高于参照组,具有统计学显著性(P < 0.05)。中医组患者的综合护理满意率为99.02%,参照组患者的综合护理满意率为80.39%,差异具有统计学意义(P < 0.05)。结论:中医护理技术在产科的应用,有助于改善患者的负性情绪,提升患者的总体满意率,护理干预价值较高。

Operating procedures of moxibustion technology

Moxibustion therapy is a treatment and health-care method that originated from China.It is a kind of therapy for preventing and treating diseases by stimulating meridians and acupoints using heat to regulate the viscera and enhance immunity.This article introduces the definition and mechanism of moxibustion technology,clinical operation technics,and precautions of moxibustion in practice,and demonstrates plenty of iconic cases of application of moxibustion in the treatment of insomnia,dysmenorrhea,urinary retention,knee arthritis,chronic eczema,etc.,so as to provide a reference for the wide application of moxibustion technology.

基于CiteSpace的慢性阻塞性肺疾病中医护理技术研究的可视化分析

目的:基于CiteSpace软件分析国内慢性阻塞性肺疾病(COPD)中医护理技术的研究概况和动态前沿,为该领域的研究提供参考依据。方法:检索中国知网中COPD中医护理技术的相关文献,使用CiteSpace 6.2.R3软件分析该研究领域作者、机构和关键词等文献特征,并结合图谱解读其含义。结果:最终纳入655篇文献,发文量整体呈先升后降趋势;已形成2个规模较大的合作团队,钱叶长是发文量最高(12篇)作者;安徽中医药大学和广州中医药大学是发文量最多(均为12篇)的研究机构;穴位敷贴等中医护理技术的应用及疗效观察是研究热点;血气指标、肺康复、子午流注、耳穴贴压、肺胀、肺功能等研究热度较高。结论:COPD中医护理技术已取得了阶段性发展,研究热点较为集中,但相关研究深度不足,建议不断丰富COPD病人中医护理研究内容,充分发挥中医护理技术在COPD人群健康管理中的独特优势。

新质生产力赋能中医药传承创新发展的策略与思考

文章探讨了新质生产力在推动中医药传承创新发展方面的策略与思考。科技创新交叉融合突破所产生的新质生产力,为中医药领域带来了前所未有的发展机遇。文章探讨了新质生产力在医药领域的潜力和发展方向,强调了其在推动中医药传承创新中的重要作用;分析了现代信息技术对中医药传承创新发展的影响,重点介绍了中药材大数据云服务平台、人工智能赋能、先进设备智能制造、大数据超算以及中医药循证研究证据库等方面的应用;展望了人工智能大模型在医药领域的发展方向,为未来中医药传承创新发展提供了新的视角和思路。

中医护理技术的应用及发展现状研究

国务院在2016年2月26日印发的《中医药发展战略规划纲要(2016-2030年)》中,明确提出到2020年要实现人人基本享有中医药服务。中医护理是中医药服务重要的组成部分。中医护理技术是中医护理的重要组成部分,其种类丰富并具有简、便、验、廉的特点,在临床疾病护理、治未病、慢性病防治和养生康复中发挥着重要作用。文章旨在总结近年来中医护理技术在临床中的应用及发展情况,发掘目前亟待解决的问题,并对其未来的发展进行展望,以期为中医护理技术的规范化发展提供客观的参考。

深圳市公立中医医院医疗服务价格改革历程与思考

通过梳理深圳市公立中医医院医疗服务价格改革历程,分析优势与难点,提出动态调整中医药服务价格,定价应体现中医劳务价值和技术价值,完善医疗服务价格目录,建立中医医疗技术评定指标体系等建议,以助推中医药综合改革,优化深圳中医医疗服务价格改革模式。

综合性医科大学中药学专业建设的实践与思考——以首都医科大学为例

首都医科大学中药学专业在长期办学实践中分析身处综合性医科大学的教育教学资源特点,结合生源及其就业趋向,逐步树立了院校教育与师承教育相结合培养中药专业人才的精品教育理念,实施一系列深化中药学专业教育教学综合改革的措施,使人才培养质量显著提升。通过专业认证更加明确自身存在的问题,并制定了持续推进国家级一流专业建设、进一步提升人才培养质量的具体措施。

糖尿病患者应用中医适宜技术预后不良的危险因素分析与路径

目的分析糖尿病患者应用中医适宜技术预后不良的危险因素与路径研究。方法纳入120例应用中医适宜技术干预的糖尿病患者为研究对象,并将其按预后情况分成预后良好组80例、预后不良组40例,统计分析糖尿病患者的临床基本资料。比较2组健康调查简表(SF-36)、血糖相关指标(空腹血糖、餐后2 h血糖及糖化血红蛋白)水平,应用单因素分析及多因素Logistic回归分析糖尿病患者预后不良情况的主要危险因素。结果良好组SF-36各项评分均高于不良组患者(P<0.05)。良好组空腹血糖、餐后2 h血糖及糖化血红蛋白水平均低于不良组(P<0.05)。单因素分析显示,糖尿病患者预后不良情况发生与性别、高血压、吸烟、文化程度无关,比较差异无统计学意义(P>0.05);主要与年龄、体质量指数(BMI)、血脂异常、病程、糖尿病家族史、治疗依从性、科学运动、丙氨酸氨基转移酶(ALT)水平有关,比较差异有统计学意义(P<0.05)。Logistic回归分析结果发现,年龄≥70岁、BMI肥胖或超重、病程长短、血脂异常、糖尿病家族史、未科学运动、治疗依从性差、ALT升高为糖尿病患者发生预后不良情况的主要危险因素(P<0.05)。以糖尿病患者预后是否发生预后不良为因变量,发现病程、BMI、年龄、血脂异常、科学运动、治疗依从性、ALT、糖尿病家族史对糖尿病患者发生预后不良情况具有间接的中介作用。结论通过使用中医适宜技术对糖尿病患者进行干预,可有效改善患者的血糖指标及生活质量,糖尿病患者预后不良情况主要与年龄、病程、BMI指数、糖尿病家族史、血脂异常、ALT相关,为临床改善患者预后情况提供了参考。

中医外科技术结合长皮膏在术后创面修复中的临床应用

目的观察中医外科技术结合长皮膏方案在术后创面修复中的临床疗效。方法回顾性收集临床术后创面病例65例,采用中医外科技术结合长皮膏的综合治疗方案,自身前后对照,观察临床效果。结果术后创面65例,其中肿瘤术后33例(口腔颌面肿瘤术后18例,乳腺肿瘤术后10例,阴部肿瘤术后3例,肺癌术后病例2例),跟腱断裂术后6例,心脏搭桥术后6例,下肢内固定取出术后3例,皮脂腺囊肿切排术后4例,肛旁脓肿术后3例,血管瘤切除术后2例,植皮术后5例,剖腹产术后3例。结果治愈62例,无效3例,无效病例中1例骨髓炎,2例肿瘤复发转移。治愈患者愈合时间最短6 d,最长时间184 d。结论中医外科技术结合长皮膏在术后创面修复中的临床疗效明显,能促进术后创面修复,避免再次手术。